Glutamate microinjection at the medial preoptic area enhances slow wave sleep in rats

Behavioural Brain Research

Volumn 217, Issue 1, 2011, Pages 240-243

  Kaushik, Mahesh K ^a   Kumar, Velayudhan Mohan ^b   Mallick, Hruda Nanda ^a  

^a ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

^b SREE CHITRA TIRUNAL INSTITUTE FOR MEDICAL SCIENCES AND TECHNOLOGY   (India)

Author keywords

Glutamate; Medial preoptic area; Microinjection; Sleep wakefulness

Indexed keywords

GLUTAMATE SODIUM;

ANIMAL EXPERIMENT; CONTROLLED STUDY; ELECTROENCEPHALOGRAM; ELECTROMYOGRAM; ELECTROOCULOGRAM; HABITUATION; LETTER; MALE; MEDIAL PREOPTIC AREA; MICROINJECTION; NEUROMODULATION; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; RAT; REM SLEEP; SLEEP TIME; SLEEP WAKING CYCLE; SLOW WAVE SLEEP;

EID: 78650178106     PISSN: 01664328     EISSN: 18727549     Source Type: Journal    
DOI: 10.1016/j.bbr.2010.11.007     Document Type: Article

References (22)

1. Alam M.A., Mallick B.N. Glutamic acid stimulation of the perifornical-lateral hypothalamic area promotes arousal and inhibits non-REM/REM sleep. Neurosci Lett 2008, 439:281-286.
2. Azuma S., Kodama T., Honda K., Inoue S. State-dependent changes of extracellular glutamate in the medial preoptic area in freely behaving rats. Neurosci Lett 1996, 214:179-182.
3. Bagga N., Chhina G.S., Kumar V.M., Singh B. Mechanism of participation of medial preoptic area in the hippocampal inhibition of ovulation. Brain Res 1981, 216:444-448.
4. Brann D.W. Glutamate: a major excitatory transmitter in neuroendocrine regulation. Neuroendocrinology 1995, 61:213-225.
5. Datta S. Evidence that REM sleep is controlled by the activation of brain stem pedunculopontine tegmental kainate receptor. J Neurophysiol 2002, 87:1790-1798.
6. Datta S. Cellular and chemical neuroscience of mammalian sleep. Sleep Med 2010, 11:431-440.
7. Datta S., Maclean R.R. Neurobiological mechanisms for the regulation of mammalian sleep-wake behavior: reinterpretation of historical evidence and inclusion of contemporary cellular and molecular evidence. Neurosci Biobehav Rev 2007, 31:775-824.
8. Datta S., Spoley E.E., Mavanji V.K., Patterson E.H. A novel role of pedunculopontine tegmental kainate receptors: a mechanism of rapid eye movement sleep generation in the rats. Neuroscience 2002, 114:157-164.
9. Datta S., Spoley E.E., Patterson E.H. Microinjection of glutamate into the pedunculopontine tegmentum induces REM sleep and wakefulness in the rat. Am J Physiol Regul Integr Comp Physiol 2001, 280:R752-759.
10. DeGroot J. The rat forebrain in stereotaxic coordinates. Verh Konink Nederland Akad Wetenschap Natuurkunde 1959, 52:1-40.
11. John J., Kumar V.M. Effect of NMDA lesion of the medial preoptic neurons on sleep and other functions. Sleep 1998, 21:587-598.
12. John J., Kumar V.M., Gopinath G., Ramesh V., Mallick H. Changes in sleep-wakefulness after kainic acid lesion of the preoptic area in rats. Jpn J Physiol 1994, 44:231-242.
13. John J., Ramanathan L., Siegel J.M. Rapid changes in glutamate levels in the posterior hypothalamus across sleep-wake states in freely behaving rats. Am J Physiol Regul Integr Comp Physiol 2008, 295:R2041-2049.
14. Khubchandani M., Jagannathan N.R., Mallick H.N., Mohan Kumar V. Functional MRI shows activation of the medial preoptic area during sleep. Neuroimage 2005, 26:29-35.
15. Kodama T., Lai Y.Y., Siegel J.M. Enhanced glutamate release during REM sleep in the rostromedial medulla as measured by in vivo microdialysis. Brain Res 1998, 780:178-181.
16. Lena I., Parrot S., Deschaux O., Muffat-Joly S., Sauvinet V., Renaud B., et al. Variations in extracellular levels of dopamine, noradrenaline, glutamate, and aspartate across the sleep-wake cycle in the medial prefrontal cortex and nucleus accumbens of freely moving rats. J Neurosci Res 2005, 81:891-899.
17. Mahesh V.B., Brann D.W. Regulatory role of excitatory amino acids in reproduction. Endocrine 2005, 28:271-280.
18. McGinty D.J., Sterman M.B. Sleep suppression after basal forebrain lesions in the cat. Science 1968, 160:1253-1255.
19. Nauta W.J.H. Hypothalamic regulation of sleep in rats: an experimental study. J Neurophysiol 1946, 9:285-316.
20. Onoe H., Sakai K. Kainate receptors: a novel mechanism in paradoxical (REM) sleep generation. Neuroreport 1995, 6:353-356.
21. Vetrivelan R., Mallick H.N., Kumar V.M. Sleep induction and temperature lowering by medial preoptic alpha(1) adrenergic receptors. Physiol Behav 2006, 87:707-713.
22. Wigren H.K., Schepens M., Matto V., Stenberg D., Porkka-Heiskanen T. Glutamatergic stimulation of the basal forebrain elevates extracellular adenosine and increases the subsequent sleep. Neuroscience 2007, 147:811-823.