Synthesis, characterization, antibacterial, antifungal, and immunomodulating activities of gatifloxacin derivatives

Medicinal Chemistry Research

Volumn 19, Issue 9, 2010, Pages 1210-1221

  Sultana, Najma ^a   Naz, Asia ^a,b   Khan, Bushra ^a   Arayne, M Saeed ^a   Mesaik, M Ahmed ^a  

^a UNIVERSITY OF KARACHI   (Pakistan)

^b ZIAUDDIN UNIVERSITY   (Pakistan)

Author keywords

Antibacterial activity; Antifungal activity; Derivatives; Gatifloxacin; Immunomodulatory activity

Indexed keywords

1 CYCLOPROPYL 6 FLUORO 8 METHOXY 7 (3 METHYL 4 OCTANOYLPIPERAZIN 1 YL) 4 OXO 1,4 DIHYDROQUINOLINE 3 CARBOXYLIC ACID; 7 (4 ACETYL 3 METHYLPIPERAZIN 1 YL) 1 CYCLOPROPYL 6 FLUORO 8 METHOXY 4 OXO 1,4 DIHYDROQUINOLINE 3 CARBOXYLIC ACID; 7 (4 BENZOYL 3 METHYLPIPERAZIN 1 YL) 1 CYCLOPROPYL 6 FLUORO 8 METHOXY 4 OXO 1,4 DIHYDROQUINOLINE 3 CARBOXYLIC ACID; ANTIFUNGAL AGENT; ANTIINFECTIVE AGENT; ANTIINFLAMMATORY AGENT; DIMETHYL SULFOXIDE; GATIFLOXACIN; GEMIFLOXACIN; IMMUNOMODULATING AGENT; SPARFLOXACIN; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DISK DIFFUSION; DRUG POTENCY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; ELECTROSPRAY MASS SPECTROMETRY; HETERONUCLEAR NUCLEAR MAGNETIC RESONANCE; IC 50; IMMUNOMODULATION; IN VITRO STUDY; INFRARED RADIATION; KLEBSIELLA PNEUMONIAE; NONHUMAN; PSEUDOMONAS AERUGINOSA; SHIGELLA FLEXNERI;

EID: 78650175033     PISSN: 10542523     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00044-009-9264-y     Document Type: Article

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