A modern miasma hypothesis and back-to-school asthma exacerbations

Medical Hypotheses

Volumn 76, Issue 1, 2011, Pages 113-116

  Tovey, E R ^a,b   Rawlinson, W D ^c,d  

^a WOOLCOCK INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b UNIVERSITY OF SYDNEY   (Australia)

^c PRINCE OF WALES HOSPITAL   (Australia)

^d UNIVERSITY OF NEW SOUTH WALES   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGEN; MONTELUKAST;

ARTICLE; ASTHMA; DISEASE ASSOCIATION; DISEASE EXACERBATION; ENVIRONMENTAL EXPOSURE; HERD IMMUNITY; HOST SUSCEPTIBILITY; HUMAN; IMMUNOLOGICAL TOLERANCE; RHINOVIRUS INFECTION; SCHOOL REENTRY; SENSITIZATION; VIRUS TRANSMISSION;

ASTHMA; CHILD; HUMANS; MODELS, THEORETICAL; SCHOOLS;

HUMAN RHINOVIRUS SP.;

EID: 78650173975     PISSN: 03069877     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mehy.2010.08.045     Document Type: Article

References (59)

1. Sears M.R. Epidemiology of asthma exacerbations. J Allergy Clin Immunol 2008, 122(4):662-668.
2. Khetsuriani N., Kazerouni N.N., Erdman D.D., et al. Prevalence of viral respiratory tract infections in children with asthma. J Allergy Clin Immunol 2007, 119(2):314-321.
3. Tregoning J.S., Schwarze J. Respiratory viral infections in infants: causes, clinical symptoms, virology, and immunology. Clin Microbiol Rev 2010, 23(1):74.
4. Tapparel C., Junier T., Gerlach D., et al. New respiratory enterovirus and recombinant rhinoviruses among circulating picornaviruses. Emerg Infect Dis 2009, 15(5):719-726.
5. Arden K., Mackay I. Human rhinoviruses: coming in from the cold. Genome Med 2009, 1(4):44-45.
6. Silverman R.A., Ito K., Stevenson L., Hastings H.M. The relationship of fall school opening and emergency department asthma visits in a large metropolitan area. Arch Pediatr Adolesc Med 2005, 159(9):818-823.
7. Van Dole K.B., Swern A.S., Newcomb K., Nelsen L. Seasonal patterns in health care use and pharmaceutical claims for asthma prescriptions for preschool- and school-aged children. Ann Allergy Asthma Immunol 2009, 102(3):198-204.
8. Monteil M.A., Juman S., Hassanally R., et al. Descriptive epidemiology of asthma in Trinidad, West Indies. J Asthma 2000, 37(8):677-684.
9. Harju T., Keistinen T., Tuuponen T., Kivela S.L. Seasonal variation in childhood asthma hospitalisations in Finland, 1972-1992. Eur J Pediatr 1997, 156(6):436-439.
10. Johnston N.W., Johnston S.L., Duncan J.M., et al. The September epidemic of asthma exacerbations in children: a search for etiology. J Allergy Clin Immunol 2005, 115(1):132-138.
11. Lincoln D., Morgan G., Sheppeard V., Jalaludin B., Corbett S., Beard J. Childhood asthma and return to school in Sydney, Australia. Public Health 2006, 120(9):854-862.
12. Johnston N.W., Johnston S.L., Norman G.R., Dai J., Sears M.R. The September epidemic of asthma hospitalization: school children as disease vectors. J Allergy Clin Immunol 2006, 117(3):557-562.
13. Storr J., Lenney W. School holidays and admissions with asthma. Arch Dis Child 1989, 64(1):103-107.
14. Scheuerman O., Meyerovitch J., Marcus N., Hoffer V., Batt E., Garty B.Z. The September epidemic of asthma in Israel. J Asthma 2009, 46(7):652-655.
15. Yoon H., Kim W. Effect of vitamin D and respiratory virus infection in asthmatic children. Allergy 2010, 65(Suppl. 92):109. Abs 252.
16. Weiss K., Gern J., Johnston N., et al. The back to school asthma study: the effect of montelukast on asthma burden when initiated prophylactically at the start of the school year. Ann Allergy Asthma Immunol. 2010, 105:174-181.
17. Im W., Schneider D. Effect of weed pollen on children's hospital admissions for asthma during the fall season. Arch Environ Occup Health 2005, 60(5):257-265.
18. Pulimood T.B., Corden J.M., Bryden C., Sharpies L., Nasser S.M. Epidemic asthma and the role of the fungal mold Alternaria alternata. J Allergy Clin Immunol 2007, 120(3):610-617.
19. Olenec J., Kim W., Lee W., et al. Weekly monitoring of children with asthma for infections and illness during common cold seasons. J Allergy Clin Immunol 2010, 125(5):1001-1006.
20. Rakes C.P., Arruda E., Ingram J.M., et al. Rhinovirus and respiratory syncytial virus in wheezing children requiring emergency care - IgE and eosinophil analyses. Am J Respir Crit Care Med 1999, 159(3):785-790.
21. Heymann P.W., Carper H.T., Murphy D.D., et al. Viral infections in relation to age, atopy, and season of admission among children hospitalized for wheezing. J Allergy Clin Immunol 2004, 114(2):239-247.
22. Sly P.D., Boner A.L., Bjorksten B., et al. Early identification of atopy in the prediction of persistent asthma in children. Lancet 2008, 372(9643):1100-1106.
23. Green R.M., Cusotvic A., Sanderson G., Hunter J., Johnston S.L., Woodcock A. Synergism between allergens and viruses and risk of hospital admission with asthma: case-control study. Br Med J 2002, 324(7340):763-766.
24. Murray C.S., Poletti G., Kebadze T., et al. Study of modifiable risk factors for asthma exacerbations: virus infection and allergen exposure increase the risk of asthma hospital admissions in children. Thorax 2006, 61(5):376-382.
25. Monto A.S., Bryan E.R., Ohmit S. Rhinovirus infections in Tecumseh, Michigan - frequency of illness and number of serotypes. J Infect Dis 1987, 156(1):43-49.
26. Fox J.P., Cooney M.K., Hall C.E., Foy H.M. Rhinoviruses in Seattle families, 1975-1979. Am J Epidemiol 1985, 122(5):830-846.
27. Peltola V., Waris M., Osterback R., Susi P., Ruuskanen O., Hyypia T. Rhinovirus transmission within families with children: incidence of symptomatic and asymptomatic infections. J Infect Dis 2008, 197(3):382-389.
28. Winther B., Hayden F.G., Hendley J.O. Picornavirus infections in children diagnosed by RT-PCR during longitudinal surveillance with weekly sampling: association with symptomatic illness and effect of season. J Med Virol 2006, 78(5):644-650.
29. Cauchemez S., Valleron A.J., Boelle P.Y., Flahault A., Ferguson N.M. Estimating the impact of school closure on influenza transmission from Sentinel data. Nature 2008, 452:750-756.
30. Miasma. Merriam-Webster online dictionary. Merriam-Webster online. 2010 [accessed 27.05.10]. http://www.merriam-webster.com/dictionary/miasma.
31. Huynh K.N., Oliver B.G., Stelzer S., Rawlinson W.D., Tovey E.R. A new method for sampling and detection of exhaled respiratory virus aerosols. Clin Infect Dis 2008, 46(1):93-95.
32. Stelzer-Braid S., Oliver B.G., Blazey A.J., et al. Exhalation of respiratory viruses by breathing, coughing, and talking. J Med Virol 2009, 81(9):1674-1679.
33. Blachere F., Lindsley W., Pearce T., et al. Measurement of airborne influenza virus in a hospital emergency department. Clin Infect Dis 2009, 48(4):438-440.
34. Lindsley W., Blachere F., Davis K., et al. Distribution of airborne influenza virus and respiratory syncytial virus in an urgent care medical clinic. Clin Infect Dis 2010, 50(5):693-698.
35. Korant B.D., Lonbergh K., Stasny J.T., Noble J. Naturally occurring and artificially produced components of 3 rhinoviruses. Virology 1972, 48(1):71.
36. Korant B.D., Lonbergholm K., Yin F.H., Nobleharvey J. Fractionation of biologically-active and inactive populations of human rhinovirus type 2. Virology 1975, 63(2):384-394.
37. Bukreyev A., Yang L.J., Fricke J., Cheng L., et al. The secreted form of respiratory syncytial virus G glycoprotein helps the virus evade antibody-mediated restriction of replication by acting as an antigen decoy and through effects on Fc receptor-bearing leukocytes. J Virol 2008, 82(24):12191-12204.
38. Miller E., Hoschler K., Hardelid P., Stanford E., Andrews N., Zambon M. Incidence of 2009 pandemic influenza A H1N1 infection in England: a cross-sectional serological study. Lancet 2010, 375:1100-1108.
39. De Lucca S.D., O'Meara T.J., Tovey E.R. Exposure to mite and cat allergens on a range of clothing items at home and the transfer of cat allergen in the workplace. J Allergy Clin Immunol 2000, 106(5):874-879.
40. Patchett K., Lewis S., Crane J., Fitzharris P. Cat allergen (Fel d 1) levels on school children's clothing and in primary school classrooms in Wellington, New Zealand. J Allergy Clin Immunol 1997, 100(6):755-759.
41. Tovey E.R., Mahmic A., McDonald L.G. Clothing - an important source of mite allergen exposure. J Allergy Clin Immunol 1995, 96(6):999-1001.
42. Salo P.M., Sever M.L., Zeldin D.C. Indoor allergens in school and day care environments. J Allergy Clin Immunol 2009, 124(2):185-192.
43. Amr S., Bollinger M.E., Myers M., et al. Environmental allergens and asthma in urban elementary schools. Ann Allergy Asthma Immunol 2003, 90(1):34-40.
44. Fromme H., Heitmann D., Dietrich S., et al. Air quality in schools - classroom levels of carbon di oxide (CO2), volatile organic compounds (VOC), aldehydes, endotoxins and cat allergen. Gesundheitswesen 2008, 70(2):88-97.
45. Instanes C., Hetland G., Berntsen S., Lovik M., Nafstad P. Allergens and endotoxin in settled dust from day-care centers and schools in Oslo, Norway. Indoor Air 2005, 15(5):356-362.
46. Raja S., Xu Y., Ferro A.R., Jaques P.A., Hopke P.K. Resuspension of indoor aeroallergens and relationship to lung inflammation in asthmatic children. Environ Int 2010, 36(1):8-14.
47. Rabinovitch N., Liu A.H., Zhang L.N., et al. Importance of the personal endotoxin cloud in school-age children with asthma. J Allergy Clin Immunol 2005, 116(5):1053-1057.
48. Reed C.E., Milton D.K. Endotoxin-stimulated innate immunity: a contributing factor for asthma. J Allergy Clin Immunol 2001, 108(2):157-166.
49. Lu L.F., Lind E.F., Gondek D.C., et al. Mast cells are essential intermediaries in regulatory T-cell tolerance. Nature 2006, 442:997-1002.
50. Litvinova E.A., Goncharova E.P., Zaydman A.M., Zenkova M.A., Moshkin M.P. Female scent signals enhance the resistance of male mice to influenza. PLos One 2010 Mar, 5. (3).
51. Cate T., Rossen R., Douglas R.J., Butler W., RB C. The role of nasal secretion and serum antibody in HTE rhinovirus common cold. Am J Epidemiol 1966, 84(2):352-363.
52. Dreschers S., Dumitru C.A., Adams C., Gulbins E. The cold case: are rhinoviruses perfectly adapted pathogens?. Cell Mol Life Sci 2007, 64(2):181-191.
53. Almqvist C., Wickman M., Perfetti L., et al. Worsening of asthma in children allergic to cats, after indirect exposure to cat at school. Am J Respir Crit Care Med 2001, 163(3):694-698.
54. Lonnkvist K., Hallden G., Dahlen S.E., et al. Markers of inflammation and bronchial reactivity in children with asthma, exposed to animal dander in school dust. Pediatr Allergy Immunol 1999, 10(1):45-52.
55. Linneberg A. Are we getting enough allergens?. Int Arch Allergy Immunol 2008, 147(2):93-100.
56. Biswas S.K., Lopez-Collazo E. Endotoxin tolerance. New mechanisms, molecules and clinical significance. Trends Immunol 2009, 30(10):475-487.
57. Expert panel report 3 (EPR-3): guidelines for the diagnosis and management of asthma. NIH Publication No. 08-5846. ; 2010 [accessed 13.08.10]. http://www.nhlbi.nih.gov.
58. Johnston N.W., Mandhane P.J., Dai J., et al. Attenuation of the September epidemic of asthma exacerbations in children: a randomized, controlled trial of montelukast added to usual therapy. Pediatrics 2007, 120(3):E702-E712.
59. Erwin E.A., Satinover S.M., Reefer A.J., Woodfolk J.A., Platts-Mills T.A.E. Changes in IgE and IgG antibody responses to cat with decreased exposure to cat allergen. J Allergy Clin Immunol 2007, 119(1):1213.