Teaching an Old Drug New Tricks: Metformin as a Targeted Therapy for Lung Cancer

Seminars in Thoracic and Cardiovascular Surgery

Volumn 22, Issue 3, 2010, Pages 195-196

  Antonoff, Mara B ^a   D'cunha, Jonathan ^a  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 (METHYLNITROSAMINO) 1 (3 PYRIDYL) 1 BUTANONE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INSULIN; MAMMALIAN TARGET OF RAPAMYCIN; METFORMIN; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR;

ARTICLE; CELL GROWTH; CELL PROLIFERATION; CIGARETTE SMOKING; DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG RESEARCH; DRUG TARGETING; ENZYME ACTIVATION; GROWTH INHIBITION; HUMAN; IN VIVO STUDY; INDIVIDUALIZATION; LUNG CANCER; NONHUMAN; TREATMENT OUTCOME; TREATMENT PLANNING; TUMOR VOLUME;

ANTINEOPLASTIC AGENTS; HUMANS; HYPOGLYCEMIC AGENTS; LUNG NEOPLASMS; METFORMIN; SIROLIMUS; SMOKING; TOR SERINE-THREONINE KINASES;

EID: 78650156203     PISSN: 10430679     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.semtcvs.2010.10.015     Document Type: Article

References (2)

1. Memmott R.M., Mercado J.R., Maier C.R., et al. Metformin prevents tobacco carcinogen-induced lung tumorigenesis. Cancer Prev Res (Phila) 2010, 3:1066-1076.
2. Engelman J.A., Cantley L.C. Chemoprevention meets glucose control. Cancer Prev Res (Phila) 2010, 3:1049-1052.