NMR solution structure of a DNA-actinomycin D complex containing a non-hydrogen-bonding pair in the binding site

Journal of the American Chemical Society

Volumn 132, Issue 49, 2010, Pages 17588-17598

  Cravens, Shannen L ^a   Navapanich, Alyssa C ^a   Geierstanger, Bernhard H ^b   Tahmassebi, Deborah C ^a   Dwyer, Tammy J ^a  

^a UNIVERSITY OF SAN DIEGO   (United States)

^b Genomics Institute   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTINOMYCIN D; BASE PAIRS; DNA BINDING; DNA DUPLEXES; HIGH AFFINITY; HYDROGEN BONDINGS; HYDROGEN-BONDING PATTERNS; INTERCALATORS; MOLECULAR DYNAMICS SIMULATIONS; PEPTIDE ANTIBIOTICS; SOLUTION STRUCTURES;

ANTIBIOTICS; DNA; MOLECULAR DYNAMICS; MOLECULAR ORIENTATION; PEPTIDES;

HYDROGEN;

AROMATIC COMPOUND; DACTINOMYCIN; DOUBLE STRANDED DNA; GUANINE; INTERCALATING AGENT; QUINONE DERIVATIVE;

ARTICLE; BINDING AFFINITY; BINDING SITE; CHEMICAL BOND; DNA SEQUENCE; DRUG DNA BINDING; FLUORINE NUCLEAR MAGNETIC RESONANCE; MOLECULAR DYNAMICS;

ANTI-BACTERIAL AGENTS; BASE PAIRING; BASE SEQUENCE; BINDING SITES; DACTINOMYCIN; DNA; HYDROGEN BONDING; INTERCALATING AGENTS; MOLECULAR DYNAMICS SIMULATION; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; NUCLEIC ACID CONFORMATION;

EID: 78650148250     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja107575f     Document Type: Article

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