The low-pH stability discovered in neuraminidase of 1918 pandemic influenza A virus enhances virus replication

PLoS ONE

Volumn 5, Issue 12, 2010, Pages

  Takahashi, Tadanobu ^a,b   Kurebayashi, Yuuki ^a   Ikeya, Kumiko ^a,b   Mizuno, Takashi ^a   Fukushima, Keijo ^a   Kawamoto, Hiroko ^a,b   Kawaoka, Yoshihiro ^b,c,d   Suzuki, Yasuo ^b,e   Suzuki, Takashi ^a,b  

^a UNIVERSITY OF SHIZUOKA   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c THE UNIVERSITY OF TOKYO   (Japan)

^d UNIVERSITY OF WISCONSIN MADISON   (United States)

^e CHUBU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; HEMAGGLUTININ; THREONINE; VIRUS SIALIDASE; SIALIDASE;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME STABILITY; GENE DELETION; GENE FUNCTION; GENE SEQUENCE; HUMAN; HUMAN CELL; INFLUENZA VIRUS; NONHUMAN; NUCLEOTIDE SEQUENCE; PANDEMIC INFLUENZA VIRUS A; PH; SPANISH INFLUENZA; VIRUS GENE; VIRUS MUTANT; VIRUS REPLICATION; VIRUS VIRULENCE; ANIMAL; BIOLOGICAL MODEL; CELL LINE; CHEMISTRY; DOG; ENZYMOLOGY; FLOW CYTOMETRY; INFLUENZA VIRUS A; METABOLISM; METHODOLOGY; PANDEMIC; PHYSIOLOGY; PLASMID; PROTEIN CONFORMATION;

AVES; INFLUENZA A VIRUS; ORTHOMYXOVIRIDAE;

AMINO ACIDS; ANIMALS; CELL LINE; DOGS; FLOW CYTOMETRY; HUMANS; HYDROGEN-ION CONCENTRATION; INFLUENZA A VIRUS; MODELS, GENETIC; NEURAMINIDASE; PANDEMICS; PLASMIDS; PROTEIN CONFORMATION; VIRUS REPLICATION;

EID: 78650125730     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0015556     Document Type: Article

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