Microwave tissue ablation: Biophysics, technology, and applications

Critical Reviews in Biomedical Engineering

Volumn 38, Issue 1, 2010, Pages 65-78

  Brace, Christopher L ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Hyperthermia; Microwave ablation; Thermal therapies

Indexed keywords

ABLATION; DISEASES; POWER CONTROL; TISSUE;

DESIGN AND OPERATIONS; ENGINEERING DESIGN; HYPERTHERMIA; MICROWAVE ABLATION; SYSTEM OPTIMIZATIONS; TECHNOLOGICAL DEVELOPMENT; THERMAL THERAPIES; TREATMENT DURATION;

MICROWAVES;

ABLATION THERAPY; ANGIOPLASTY; ANTENNA; DIELECTRIC CONSTANT; ELECTROMAGNETIC RADIATION; EQUIPMENT DESIGN; HEART ARRHYTHMIA; KIDNEY TUMOR; LIVER CELL CARCINOMA; LOW LEVEL LASER THERAPY; LUNG TUMOR; MEDICAL INSTRUMENTATION; MEDICAL TECHNOLOGY; METASTASIS; MICROWAVE COOKING; MICROWAVE THERAPY; OSTEOID OSTEOMA; PRIORITY JOURNAL; PROSTATE HYPERTROPHY; REVIEW; TISSUE; ULTRASOUND THERAPY; VARICOSIS;

EID: 78650079808     PISSN: 0278940X     EISSN: None     Source Type: Journal    
DOI: 10.1615/CritRevBiomedEng.v38.i1.60     Document Type: Review

References (121)

1. Bakker JF, Paulides MM, Westra AH, Schippers H, Van Rhoon GC. Design and test of a 434 MHz multi-channel amplifier system for targeted hyperthermia applicators. Int J Hyperthermia. 2010;26:158-70.
2. Converse M, Bond EJ, Van Veen BD, Hagness SC. A computational study of ultra-wideband versus narrowband microwave hyperthermia for breast cancer treatment. IEEE Trans Microw Theory Tech. 2006;54:2169-80. (Pubitemid 43746054)
3. Balanis CA. Advanced engineering electromagnetics. New York: John Wiley and Sons; 1989.
4. Pennes HH. Temperature of skeletal muscle in cerebral hemiplegia and paralysis agitans. Arch Neurol Psychiatry. 1949;62:269-79.
5. Gabriel S, Lau RW, Gabriel C. The dielectric properties of biological tissues: II. Measurements in the frequency range 10 Hz to 20 GHz. Phys Med Biol. 1996;41:2251-69.
6. Gabriel S, Lau RW, Gabriel C. The dielectric properties of biological tissues: III. Parametric models for the dielectric spectrum of tissues. Phys Med Biol. 1996;41:2271-93.
7. Schwan HP, Li K. Measurements of materials with high dielectric constant and conductivity at ultrahigh frequencies. AIEE Trans Comm Electronics. 1955;74:603-7.
8. Brady MM, Symons SA, Stuchly SS. Dielectric behavior of selected animal tissues in vitro at frequencies from 2 to 4 GHz. IEEE Trans Biomed Eng. 1981;28:305-7.
9. Stuchly MA, Athey TW, Stuchly SS, Samaras GM, Taylor G. Dielectric properties of animal tissues in vivo at frequencies 10 MHz-1 GHz. Bioelectromagnetics. 1981;2:93-103. (Pubitemid 12216259)
10. Duck FA. Physical properties of tissue: a comprehensive reference book. San Diego: Academic Press; 1990.
11. Lazebnik M, Converse MC, Booske JH, Hagness SC. Ultrawideband temperature-dependent dielectric properties of animal liver tissue in the microwave frequency range. Phys Med Biol. 2006;51:1941-55.
12. Schepps JL, Foster KR. The uhf and microwave dielectric properties of normal and tumour tissues: variation in dielectric properties with tissue water content. Phys Med Biol. 1980;25:1149-59.
13. Chin L, Sherar M. Changes in dielectric properties of ex vivo bovine liver at 915 MHz during heating. Phys Med Biol. 2001;46:197-211. (Pubitemid 32104879)
14. Brace CL. Temperature-dependent dielectric properties of liver tissue measured during thermal ablation: toward an improved numerical model. Conf Proc IEEE Eng Med Biol Soc. 2008;1:230-3.
15. Epstein BR, Foster KR. Anisotropy in the dielectric properties of skeletal muscle. Med Biol Eng Comput. 1983;21:51-5.
16. Bircan C, Barringer S. Determination of protein denaturation of muscle foods using the dielectric properties. J Food Sci. 2002;67:202-5. (Pubitemid 34190803)
17. Turner PF, Tumeh A, Schaefermeyer T. Bsd-2000 approach for deep local and regional hyperthermia: physics and technology. Strahlenther Onkol. 1989;165:738-41.
18. Feldberg I, Cronin N. A 9.2 GHz microwave applicator for the treatment of menorrhagia. IEEE MTT-S. 1998;2:755-8.
19. Bertram JM, Yang D, Converse MC, Webster JG, Mahvi DM. Antenna design for microwave hepatic ablation using an axisymmetric electromagnetic model. Biomed Eng Online. 2006;5:15.
20. Ahmed M, Liu Z, Afzal KS, Weeks D, Lobo SM, Kruskal JB, Lenkinski RE, Goldberg SN. Radiofrequency ablation: effect of surrounding tissue composition on coagulation necrosis in a canine tumor model. Radiology. 2004;230:761-7. (Pubitemid 38252874)
21. Lee JM, Youk JH, Kim YK, Han YM, Chung GH, Lee SY, Kim CS. Radio-frequency thermal ablation with hypertonic saline solution injection of the lung: ex vivo and in vivo feasibility studies. Eur Radiol. 2003;13:2540-7.
22. Goldberg SN, Gazelle GS, Solbiati L, Rittman WJ, Mueller PR. Radiofrequency tissue ablation: increased lesion diameter with a perfusion electrode. Acad Radiol. 1996;3:636-44.
23. Livraghi T, Goldberg SN, Monti F, Bizzini A, Lazzaroni S, Meloni F, Pellicanò S, Solbiati L, Gazelle GS. Saline-enhanced radio-frequency tissue ablation in the treatment of liver metastases. Radiology. 1997;202:205-10. (Pubitemid 27024128)
24. Goldberg SN, Stein MC, Gazelle GS, Sheiman RG, Kruskal JB, Clouse ME. Percutaneous radiofrequency tissue ablation: optimization of pulsed-radiofrequency technique to increase coagulation necrosis. J Vasc Interv Radiol. 1999;10:907-16.
25. Orth K, Russ D, Duerr J, Hibst R, Steiner R, Beger HG. Thermo-controlled device for inducing deep coagulation in the liver with the nd:yag laser. Lasers Surg Med. 1997;20:149-56.
26. Roberts WW, Hall TL, Ives K, Wolf JSJ, Fowlkes JB, Cain CA. Pulsed cavitational ultrasound: a noninvasive technology for controlled tissue ablation (histotripsy) in the rabbit kidney. J Urol. 2006;175:734-8.
27. Lu DSK, Raman SS, Vodopich DJ, Wang M, Sayre J, Lassman C. Effect of vessel size on creation of hepatic radiofrequency lesions in pigs: assessment of the "heat sink" effect. AJR Am J Roentgenol. 2002;178:47-51.
28. Yu NC, Raman SS, Kim YJ, Lassman C, Chang X, Lu DSK. Microwave liver ablation: influence of hepatic vein size on heat-sink effect in a porcine model. J Vasc Interv Radiol. 2008;19:1087-92.
29. Bhardwaj N, Strickland AD, Ahmad F, Atanesyan L, West K, Lloyd DM. A comparative histological evaluation of the ablations produced by microwave, cryotherapy and radiofrequency in the liver. Pathology. 2009;41:168-72.
30. Laeseke PF, Lee FT Jr, Sampson LA, van der Weide DW, Brace CL. Microwave ablation versus radiofrequency ablation in the kidney: high-power triaxial antennas create larger ablation zones than similarly sized internally cooled electrodes. J Vasc Interv Radiol. 2009;20:1224-9.
31. Brace CL, Hinshaw JL, Laeseke PF, Sampson LA, Lee FT Jr. Pulmonary thermal ablation: comparison of radiofrequency and microwave devices by using gross pathologic and CT findings in a swine model. Radiology. 2009;251:705-11.
32. Wright AS, Sampson LA, Warner TF, Mahvi DM, Lee FT Jr. Radiofrequency versus microwave ablation in a hepatic porcine model. Radiology. 2005;236:132-9.
33. Andreano A, Huang Y, Meloni F, Lee FT Jr, Brace CL. Microwaves create larger ablations than radiofrequency when controlled for power in ex vivo tissue. Med Phys. 2009;37:2967-73.
34. Brace CL, Laeseke PF, Sampson LA, Frey TM, van der Weide DW, Lee FT Jr. Microwave ablation with a single small-gauge triaxial antenna: in vivo porcine liver model. Radiology. 2007;242:435-40.
35. Brace CL, Laeseke PF, Sampson LA, Frey TM, van der Weide DW, Lee FT Jr. Microwave ablation with multiple simultaneously powered small-gauge triaxial antennas: results from an in vivo swine liver model. Radiology. 2007;244:151-6.
36. Strickland AD, Clegg PJ, Cronin NJ, Swift B, Festing M, West KP, Robertson GS, Lloyd DM. Experimental study of large-volume microwave ablation in the liver. Br J Surg. 2002;89:1003-7.
37. Hines-Peralta AU, Pirani N, Clegg P, Cronin N, Ryan TP, Liu Z, Goldberg SN. Microwave ablation: results with a 2.45-GHz applicator in ex vivo bovine and in vivo porcine liver. Radiology. 2006;239:94-102.
38. Skinner MG, Iizuka MN, Kolios MC, Sherar MD. A theoretical comparison of energy sources - microwave, ultrasound and laser - for interstitial thermal therapy. Phys Med Biol. 1998;43:3535-47.
39. Kuang M, Lu MD, Xie XY, Xu HX, Mo LQ, Liu GJ, Xu ZF, Zheng YL, Liang JY. Liver cancer: increased microwave delivery to ablation zone with cooled-shaft antenna - experimental and clinical studies. Radiology. 2007;242:914-24.
40. Sun Y, Wang Y, Ni X, Gao Y, Shao Q, Liu L, Liang P. Comparison of ablation zone between 915- and 2,450-MHz cooled-shaft microwave antenna: results in in vivo porcine livers. AJR Am J Roentgenol. 2009;192:511-14.
41. Tse HF, Liao S, Siu CW, Yuan L, Nicholls J, Leung G, Ormsby T, Feld GK, Lau CP. Determinants of lesion dimensions during transcatheter microwave ablation. Pacing Clin Electrophysiol. 2009;32:201-8.
42. Brace CL. Microwave ablation technology: what every user should know. Curr Probl Diagn Radiol. 2009;38:61-7.
43. Geraghty PR, Kee ST, McFarlane G, Razavi MK, Sze DY, Dake MD. CT-guided transthoracic needle aspiration biopsy of pulmonary nodules: needle size and pneumothorax rate. Radiology. 2003;229:475-81.
44. Brace CL, Laeseke PF, van der Weide DW, Lee FT. Microwave ablation with a triaxial antenna: results in ex vivo bovine liver. IEEE Trans Microw Theory Tech. 2005;53:215-20.
45. Liang P, Wang Y, Yu X, Dong B. Malignant liver tumors: treatment with percutaneous microwave ablation - complications among cohort of 1136 patients. Radiology. 2009 Jun;251(3):933-40.
46. Wolf FJ, Grand DJ, Machan JT, Dipetrillo TA, Mayo-Smith WW, Dupuy DE. Microwave ablation of lung malignancies: effectiveness, CT findings, and safety in 50 patients. Radiology. 2008;247:871-9.
47. Sato M, Watanabe Y, Ueda S, Iseki S, Abe Y, Sato N, Kimura S, Okubo K, Onji M. Microwave coagulation therapy for hepatocellular carcinoma. Gastroenterology. 1996;110:1507-14.
48. Seki T, Wakabayashi M, Nakagawa T, Itho T, Shiro T, Kunieda K, Sato M, Uchiyama S, Inoue K. Ultrasonically guided percutaneous microwave coagulation therapy for small hepatocellular carcinoma. Cancer. 1994;74:817-25.
49. Gu Z, Rappaport CM, Wang PJ, VanderBrink BA. A 2 1/4-turn spiral antenna for catheter cardiac ablation. IEEE Trans Biomed Eng. 1999;46:1480-2.
50. Brace CL, van der Weide DW, Lee FT, Laeseke PF, Sampson L. Analysis and experimental validation of a triaxial antenna for microwave tumor ablation. IEEE MTTS Int Microw Symp. 2004;3:1437-40.
51. Labonte S, Blais A, Legault S, Ali H, Roy L. Monopole antennas for microwave catheter ablation. IEEE Trans Microwave Theory Tech. 1996;44:1832-40.
52. de Sieyes DC, Douple EB, Strohbehn JW, Trembly BS. Some aspects of optimization of an invasive microwave antenna for local hyperthermia treatment of cancer. Med Phys. 1981;8:174-83.
53. Hurter W, Reinbold F, Lorenz W. A dipole antenna for interstitial microwave hyperthermia. IEEE Trans Microwave Theory Tech. 1991;39:1048-54.
54. Schaller G, Erb J, Engelbrecht R. Field simulation of dipole antennas for interstitial microwave hyperthermia. IEEE Trans Microwave Theory Tech. 1996;44:887-95.
55. Ahn H, Lee K. Interstitial antennas tipped with reactive load. IEEE Microwave Wireless Comp Lett. 2005;15:215-20.
56. Hamada L, Saito K, Yoshimura H, Ito K. Dielectric-loaded coaxial-slot antenna for interstitial microwave hyperthermia: longitudinal control of heating patterns. Int J Hyperthermia. 2000;16:219-29.
57. Ito K, Hyodo M, Shimura M, Kasai H. Thin applicator having coaxial ring slots for interstitial microwave hyperthermia. Ant Prop Soc Int Sym. 1990;3:1233-6.
58. Longo I, Gentili G, Cerretelli M, Tosoratti N. A coaxial antenna with miniaturized choke for minimally invasive interstitial heating. IEEE Trans Microwave Theory Tech. 2003;50:82-8.
59. Pisa S, Cavagnaro M, Bernardi P, Lin JC. A 915-MHz antenna for microwave thermal ablation treatment: physical design, computer modeling and experimental measurement. IEEE Trans Biomed Eng. 2001;48:599-601.
60. Lin JC, Wang YJ. The cap-choke catheter antenna for microwave ablation treatment. IEEE Trans Biomed Eng. 1996;43:657-60.
61. Wong TZ, Trembly BS. A theoretical model for input impedance of interstitial microwave antennas with choke. Int J Radiat Oncol Biol Phys. 1994;28:673-82.
62. Yang D, Bertram JM, Converse MC, O'Rourke AP, Webster JG, Hagness SC, Will JA, Mahvi DM. A floating sleeve antenna yields localized hepatic microwave ablation. IEEE Trans Biomed Eng. 2006;53:533-7.
63. Liu P, Rappaport CM. A helical microwave antenna for welding plaque during balloon angioplasty. IEEE Trans Microw Theory Tech. 1996;44:1819-31.
64. Shock SA, Meredith K, Warner TF, Sampson LA, Wright AS, Winter TC 3rd, Mahvi DM, Fine JP, Lee FT Jr. Microwave ablation with loop antenna: in vivo porcine liver model. Radiology. 2004;231:143-9.
65. Yeh MM, Trembly BS, Douple EB, Ryan TP, Hoopes PJ, Jonsson E, Heaney JA. Theoretical and experimental analysis of air cooling for intracavitary microwave hyperthermia applicators. IEEE Trans Biomed Eng. 1994;41:874-82.
66. Knavel EM, Sampson LA, Lubner M, Hinshaw JL, Andreano A, Lee FT Jr, Brace CL. High-powered gas-cooled microwave ablation: Shaft cooling creates an effective stich zone without preserving peri-antenna tissue. World Conference on Interventional Oncology, Philadelphia, PA, 2010 Jun 9-12.
67. Steinke K, King J, Glenn DW, Morris DL. Percutaneous radiofrequency ablation of lung tumors with expandable needle electrodes: tips from preliminary experience. AJR Am J Roentgenol. 2004;183:605-11.
68. Laeseke P, Sampson L, Lee FJ, Brace C. Spatially distributing power improves thermal profiles and reduces invasiveness. J Intervent Oncol. 2009;2:13-8.
69. Lee JM, Han JK, Kim HC, Kim SH, Kim KW, Joo SM, Choi BI. Multiple-electrode radiofrequency ablation of in vivo porcine liver: comparative studies of consecutive monopolar, switching monopolar versus multipolar modes. Invest Radiol. 2007;42:676-83.
70. Laeseke PF, Sampson LA, Frey TM, Mukherjee R, Winter TC3, Lee FT Jr, Brace CL. Multiple-electrode radiofrequency ablation: comparison with a conventional cluster electrode in an in vivo porcine kidney model. J Vasc Interv Radiol. 2007;18:1005-10.
71. Laeseke PF, Sampson LA, Haemmerich D, Brace CL, Fine JP, Frey TM, Winter TC 3rd, Lee FT Jr. Multiple-electrode radiofrequency ablation creates confluent areas of necrosis: in vivo porcine liver results. Radiology. 2006;241:116-24.
72. Wright AS, Lee FT Jr, Mahvi DM. Hepatic microwave ablation with multiple antennae results in synergistically larger zones of coagulation necrosis. Ann Surg Oncol. 2003;10:275-83.
73. Simon CJ, Dupuy DE, Iannitti DA, Lu DS, Yu NC, Aswad BI, Busuttil RW, Lassman C. Intraoperative triple antenna hepatic microwave ablation. AJR Am J Roentgenol. 2006;187:W333-40.
74. Jones KM, Mechling JA, Strohbehn JW, Trembly BS. Theoretical and experimental SAR distributions for interstitial dipole antenna arrays used in hyperthermia. IEEE Trans Microw Theory Tech. 1989;37:1200-9.
75. Furse CM, Iskander MF. Three-dimensional electromagnetic power deposition in tumors using interstitial antenna arrays. IEEE Trans Biomed Eng. 1989;36:977-86.
76. Lyons BE, Britt RH, Strohbehn JW. Localized hyperthermia in the treatment of malignant brain tumors using an interstitial microwave antenna array. IEEE Trans Biomed Eng. 1984;31:53-62.
77. Turner PF. Regional hyperthermia with an annular phased array. IEEE Trans Biomed Eng. 1984;31:106-14.
78. Magin RL, Peterson AF. Noninvasive microwave phased arrays for local hyperthermia: a review. Int J Hyperthermia. 1989;5:429-50.
79. Trembly BS. The effects of driving frequency and antenna length on power deposition within a microwave antenna array used for hyperthermia. IEEE Trans Biomed Eng. 1985;32:152-7.
80. Turner PF. Interstitial equal-phased arrays for EM hyperthermia. IEEE Trans Microw Theory Tech. 1986;34:572-8.
81. Trembly BS, Wilson AH, Sullivan MJ, Stein AD, Wong TZ, Strohbehn JW. Control of the SAR pattern within an interstitial microwave array through variation of antenna driving phase. IEEE Trans Microw Theory Tech. 1986;34:568-71.
82. Brace C, Laeseke P, Sampson L, van der Weide D, Lee FT Jr. Switched-mode microwave ablation: less dependence on tissue properties leads to more consistent ablations than phased arrays. Presented at the Radiological Society of North America Annual Meeting, Chicago, IL; 9-14 Jun 2007.
83. Oshima F, Yamakado K, Nakatsuka A, Takaki H, Makita M, Takeda K. Simultaneous microwave ablation using multiple antennas in explanted bovine livers: relationship between ablative zone and antenna. Radiat Med. 2008;26:408-14.
84. Hope WW, Schmelzer TM, Newcomb WL, Heath JJ, Lincourt AE, Norton HJ, Heniford BT, Iannitti DA. Guidelines for power and time variables for microwave ablation in an in vivo porcine kidney. J Surg Res. 2009 May 15;153(2):263-7.
85. Simon CJ, Dupuy DE, Mayo-Smith WW. Microwave ablation: principles and applications. Radiographics. 2005;25 Suppl 1:S69-83.
86. Duan YQ, Gao YY, Ni XX, Wang Y, Feng L, Liang P. Changes in peripheral lymphocyte subsets in patients after partial microwave ablation of the spleen for secondary splenomegaly and hypersplenism: a preliminary study. Int J Hyperthermia. 2007;23:467-72.
87. Lin J, Hirai S, Chiang C, Hsu W, Su J, Wang Y. Computer simulation and experimental studies of sar distributions of interstitial arrays of sleeved-slot microwave antennas for hyperthermia treatment of brain tumors. IEEE Trans Microw Theory Tech. 2000;48:2191-8.
88. Tsutsui H, Usuda J, Kubota M, Yamada M, Suzuki A, Shibuya H, Miyajima K, Tanaka K, Sugino K, Ito K, Kato H. Endoscopic tumor ablation for laryngotracheal intraluminal invasion secondary to advanced thyroid cancer. Acta Otolaryngol. 2008;128:799-807.
89. Singletary SE. Minimally invasive ablation techniques in breast cancer treatment. Ann Surg Oncol. 2002;9:319-20.
90. Abe T, Shinzawa H, Wakabayashi H, Aoki M, Sugahara K, Iwaba A, Haga H, Miyano S, Terui Y, Mitsuhashi H, Watanabe H, Matsuo T, Saito K, Saito T, Togashi H, Takahashi T. Value of laparoscopic microwave coagulation therapy for hepatocellular carcinoma in relation to tumor size and location. Endoscopy. 2000;32:598-603.
91. Liang P, Wang Y. Microwave ablation of hepatocellular carcinoma. Oncology. 2007;72 Suppl 1:124-31.
92. Shibata T, Iimuro Y, Yamamoto Y, Maetani Y, Ametani F, Itoh K, Konishi J. Small hepatocellular carcinoma:comparison of radio-frequency ablation and percutaneous microwave coagulation therapy. Radiology. 2002;223:331-7.
93. Seki T, Wakabayashi M, Nakagawa T, Imamura M, Tamai T, Nishimura A, Yamashiki N, Inoue K. Percutaneous microwave coagulation therapy for solitary metastatic liver tumors from colorectal cancer: a pilot clinical study. Am J Gastroenterol. 1999;94:322-7.
94. Shibata T, Niinobu T, Ogata N, Takami M. Microwave coagulation therapy for multiple hepatic metastases from colorectal carcinoma. Cancer. 2000;89:276-84.
95. Shiomi H, Naka S, Sato K, Demura K, Murakami K, Shimizu T, Morikawa S, Kurumi Y, Tani T. Thoracoscopy-assisted magnetic resonance guided microwave coagulation therapy for hepatic tumors. Am J Surg. 2008;195:854-60.
96. Lu MD, Xu HX, Xie XY, Yin XY, Chen JW, Kuang M, Xu ZF, Liu GJ, Zheng YL. Percutaneous microwave and radiofrequency ablation for hepatocellular carcinoma: a retrospective comparative study. J Gastroenterol. 2005;40:1054-60.
97. Yu NC, Lu DS, Raman SS, Dupuy DE, Simon CJ, Lassman C, Aswad BI, Ianniti D, Busuttil RW. Hepatocellular carcinoma:microwave ablation with multiple straight and loop antenna clusters - pilot comparison with pathologic findings. Radiology. 2006;239:269-75.
98. Yin XY, Xie XY, Lu MD, Xu HX, Xu ZF, Kuang M, Liu GJ, Liang JY, Lau WY. Percutaneous thermal ablation of medium and large hepatocellular carcinoma: long-term outcome and prognostic factors. Cancer. 2009;115:1914-23.
99. Furukawa K, Miura T, Kato Y, Okada S, Tsutsui H, Shimatani H, Kajiwara N, Taira M, Saito M, Kato H. Microwave coagulation therapy in canine peripheral lung tissue. J Surg Res. 2005;123:245-50.
100. Durick NA, Laeseke PF, Broderick LS, Lee FT Jr, Sampson LA, Frey TM, Warner TF, Fine JP, van der Weide DW, Brace CL. Microwave ablation with triaxial antennas tuned for lung:results in an in vivo porcine model. Radiology. 2008;247:80-7.
101. Pandharipande PV, Gervais DA, Mueller PR, Hur C, Gazelle GS. Radiofrequency ablation versus nephron-sparing surgery for small unilateral renal cell carcinoma: cost-effectiveness analysis. Radiology. 2008;248:169-78.
102. Kigure T, Harada T, Yuri Y, Fujieda N, Satoh Y. Experimental study of microwave coagulation of a VX-2 carcinoma implanted in rabbit kidney. Int J Urol. 1994;1:23-7.
103. Clark PE, Woodruff RD, Zagoria RJ, Hall MC. Microwave ablation of renal parenchymal tumors before nephrectomy: phase I study. AJR Am J Roentgenol. 2007;188:1212-4.
104. Simon CJ, Dupuy DE. Image-guided ablative techniques in pelvic malignancies: radiofrequency ablation, cryoablation, microwave ablation. Surg Oncol Clin N Am. 2005;14:419-31.
105. Carrafiello G, Laganà D, Pellegrino C, Fontana F, Mangini M, Nicotera P, Petullà M, Bracchi E, Genovese E, Cuffari S, Fugazzola C. Percutaneous imaging-guided ablation therapies in the treatment of symptomatic bone metastases: preliminary experience. Radiol Med. 2009;114:608-25.
106. Fan Q, Ma B, Zhou Y, Zhang M, Hao X. Bone tumors of the extremities or pelvis treated by microwave-induced hyperthermia. Clin Orthop Relat Res. 2003 Jan;(406):165-75.
107. Bolmsjö M, Wagrell L, Hallin A, Eliasson T, Erlandsson BE, Mattiasson A. The heat is on - but how? a comparison of TUMT devices. Br J Urol. 1996;78:564-72.
108. Blute ML, Patterson DE, Segura JW, Tomera KM, Hellerstein DK. Transurethral microwave thermotherapy v sham treatment: double-blind randomized study. J Endourol. 1996;10:565-73.
109. Armstrong N, Vale L, Deverill M, Nabi G, McClinton S, N'Dow J, Pickard R. Surgical treatments for men with benign prostatic enlargement:cost effectiveness study. BMJ. 2009;338:b1288.
110. Yu X, Elliott SP, Wilt TJ, McBean AM. Practice patterns in benign prostatic hyperplasia surgical therapy:the dramatic increase in minimally invasive technologies. J Urol. 2008;180:241-5.
111. Ellis DS, Manny TB Jr, Rewcastle JC. Focal cryosurgery followed by penile rehabilitation as primary treatment for localized prostate cancer: initial results. Urology. 2007;70:9-15.
112. Barqawi AB, Crawford ED. The current use and future trends of focal surgical therapy in the management of localized prostate cancer. Cancer J. 2007;13:313-7.
113. Melby SJ, Zierer A, Kaiser SP, Schuessler RB, Damiano RJJ. Epicardial microwave ablation on the beating heart for atrial fibrillation:the dependency of lesion depth on cardiac output. J Thorac Cardiovasc Surg. 2006;132:355-60.
114. Molloy TA. Midterm clinical experience with microwave surgical ablation of atrial fibrillation. Ann Thorac Surg. 2005;79:2115-8.
115. Comas GM, Imren Y, Williams MR. An overview of energy sources in clinical use for the ablation of atrial fibrillation. Semin Thorac Cardiovasc Surg. 2007;19:16-24.
116. Bakir I, Casselman FP, Brugada P, Geelen P, Wellens F, Degrieck I, Van Praet F, Vermeulen Y, De Geest R, Vanermen H. Current strategies in the surgical treatment of atrial fibrillation:review of the literature and Onze Lieve Vrouw Clinic's strategy. Ann Thorac Surg. 2007;83:331-40.
117. Vicol C, Kellerer D, Petrakopoulou P, Kaczmarek I, Lamm P, Reichart B. Long-term results after ablation for long-standing atrial fibrillation concomitant to surgery for organic heart disease:is microwave energy reliable?. J Thorac Cardiovasc Surg. 2008;136:1156-9.
118. Sharma B, Preston J, Ray C. Microwave endometrial ablation for menorrhagia:outcome at 2 years - experience of a district general hospital. J Obstet Gynaecol. 2004;24:916-9.
119. Nardone DT, Smith DL, Martinez-Hernandez A, Consigny PM, Kosman Z, Rosen A, Walinsky P. Microwave thermal balloon angioplasty in the atherosclerotic rabbit. Am Heart J. 1994;127:198-203.
120. Richards RG, Kääb MJ. Microwave-enhanced fixation of rabbit articular cartilage. J Microsc. 1996;181:269-76.
121. Subwongcharoen S, Praditphol N, Chitwiset S. Endovenous microwave ablation of varicose veins:in vitro, live swine model, and clinical study. Surg Laparosc Endosc Percutan Tech. 2009;19:170-4.