Alcohol Levels Do Not Accurately Predict Physical or Mental Impairment in Ethanol-Tolerant Subjects: Relevance to Emergency Medicine and Dram Shop Laws

Journal of Medical Toxicology

Volumn 6, Issue 4, 2010, Pages 438-442

  Roberts, James R ^a   Dollard, Denis ^b  

^a MERCY CATHOLIC MEDICAL CENTER   (United States)

^b Mercy Hospital of Philadelphia   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; AMYLASE; HEMOGLOBIN; LIVER ENZYME; OXAZEPAM; PHENYTOIN; POTASSIUM; TRIACYLGLYCEROL LIPASE;

ABDOMINAL PAIN; ADULT; ALCOHOL BLOOD LEVEL; ALCOHOL INTOXICATION; ALCOHOL TOLERANCE; ALCOHOL WITHDRAWAL; ANEMIA; ARTICLE; BLOOD PRESSURE; BREATH ANALYSIS; CASE REPORT; CLINICAL EXAMINATION; COGNITION; CONFUSION; CRANIAL NERVE; EMERGENCY PHYSICIAN; EMERGENCY WARD; FOOD INTAKE; GAIT; GLASGOW COMA SCALE; GRAND MAL SEIZURE; HUMAN; LABORATORY TEST; LOADING DRUG DOSE; MALE; MENTAL HEALTH; NEUROLOGIC EXAMINATION; NYSTAGMUS; ORIENTATION; PATIENT COMPLIANCE; POTASSIUM BLOOD LEVEL; PREDICTION; PROPHYLAXIS; REPEAT PROCEDURE; SENSORY EVALUATION; SLURRED SPEECH; VITAL SIGN;

ADULT; ALCOHOL DRINKING; ALCOHOLIC INTOXICATION; CENTRAL NERVOUS SYSTEM DEPRESSANTS; DRUG TOLERANCE; EMERGENCY MEDICAL SERVICES; ETHANOL; HUMANS; LEGISLATION, DRUG; MALE; PREDICTIVE VALUE OF TESTS;

EID: 78650069082     PISSN: 15569039     EISSN: 19376995     Source Type: Journal    
DOI: 10.1007/s13181-010-0048-z     Document Type: Article

References (32)

1. Yip L (2006) Ethanol. In: Flomenbaum N, Goldfrank L, Hoffman R, Howland MA, Lewin N, Nelson L (eds) Goldfrank's toxicologic emergencies, 8th edn. McGraw-Hill, New York, pp 1153-1154.
2. Garriott JC (2008) In: Garriott JC (ed) Garriott's medicolegal aspects of alcohol, 5th edn. Lawyers & Judges, Tucson, p 28.
3. USDHHS, National Institute on Alcohol Abuse and Alcoholism (1998) Fourth special report to Congress on alcohol and health. In: Goldfrank LR, Flomenbaum NE, Lewin NA, Weisman RS, Howland MA, Hoffman RS (eds) Goldfrank's toxicologic emergencies, 6th edn. Appleton & Lange, Norwalk, p 1027.
4. Finnell JT, McMicken DB (2009) In: Marx J, Hockberger R, Walls R, Adams JG et al (eds) Rosen's emergency medicine: concepts and clinical practice, 7th edn. Mosby/Elsevier, Philadelphia, p 2372.
5. Redmond AD (1986) Central nervous system depression and high blood ethanol levels. Lancet 327(8484): 805.
6. Redmond AD (1983) Blood alcohol concentrations and conscious level. Alcohol Alcoholism 18: 89-91.
7. Goldberg L (1943) Quantitative studies on alcohol tolerance in man. Acta Physiol Scand 5(suppl 16): 1.
8. deWit H, Uhlenhuth EH, Pierri J et al (1987) Individual differences in behavior and subjective responses to alcohol. Alcohol Clin Exp Res 11: 51-59.
9. Brick J, Erickson CK (2009) Intoxication is not always visible: an unrecognized prevention challenge. Alcohol Clin Exper Res 33: 1489-1507.
10. Jones AW (1999) The drunkest drinking driver in Sweden: blood alcohol concentration 0. 545% w/v. J Stud Alc 60: 400-406.
11. Hammond KB, Rumack BH, Rodgerson DO (1973) Blood ethanol: a report of unusually high levels in a living patient. JAMA 226: 63-64.
12. Bennett RH, Cherek DR, Spiga R (1993) Acute and chronic alcohol tolerance in humans: effect of dose and consecutive days of exposure. Alcohol Clin Exp Res 17: 740-745.
13. Hiltunen AJ (1997) Acute alcohol tolerance in cognitive and psychomotor performance: influence of the alcohol dose and prior alcohol experience. Alcohol 14: 125-130.
14. Marczinski CA, Fillmore MT (2009) Acute alcohol tolerance on subjective intoxication and simulated driving performance in binge drinkers. Psychol Addict Behav 2: 238-247.
15. Evans S, Levin FR (2004) Differential response to alcohol in light and moderate drinkers. Behav Pharmcol 15: 167-181.
16. Brumback T, Cao D, King A (2007) Effects of alcohol on psychomotor performance and perceived impairment in heavy binge social drinkers. Drug Alcohol Depend 9: 10-17.
17. Fillmore MT, Vogel-Sprott M (1996) Social drinking history, behavioral tolerance and the expectation of alcohol. Psychopharmacology (Berl) 127: 359-365.
18. Fillmore MT, Sprott-Vogel M (1995) Behavioral effects of alcohol in novice and experienced drinkers: alcohol expectancies and impairment. Psychopharmacology (Berl) 122: 175-184.
19. Johnson RA, Noll EC, Rodney WM (1982) Survival after a serum ethanol concentration of 1 1/2%. Lancet 2: 1394.
20. Sullivan JB Jr, Hauptman M, Bronstein AC (1987) Lack of observable intoxication in humans with high plasma alcohol concentration. J Forensic Sci 32: 1660-1665.
21. Wantanabe A, Kobayash M, Hobara BS et al (1985) A report of unusually high blood ethanol and acetaldehyde levels in two surviving patients. Alcoholism Clin Exp Res 9: 14-16.
22. Urso T, Gavaler JS, van Thiel DH (1981) Blood ethanol levels in sober alcohol users seen in an emergency room. Life Sci 28: 1053-1056.
23. Perper JA, Twerski A, Wienand JW (1986) Tolerance at high blood alcohol concentrations: a study of 110 cases and review of the literature. J Forensic Sci 31: 212-221.
24. Lindbald B, Olsson R (1976) Unusually high levels of blood alcohol. JAMA 236: 1600-1602.
25. Davis AR, Lipson AH (1986) Central nervous system tolerance to high blood alcohol levels. Med J Aust 144: 9-12.
26. Langenbucher JW, Nathan PE (1983) Psychology, public policy, and the evidence for alcohol intoxication. Am Psychol 38: 1070-1077.
27. Brick J, Carpenter JA (2001) The identification of alcohol intoxication by police. Alcohol Clin Exp Res 25: 850-855.
28. Moskowitz H, Burns M, Ferguson S (1999) Police officers' detection of breath odors from alcohol ingestion. Accid Anal Preven 31: 175-180.
29. Carroll N, Rosenberg H, Funke S (1988) Recognition of intoxication by alcohol counselors. J Subs Abuse Treat 5: 239-246.
30. Galbraith S, Murray WR, Patel AR (1976) The relationship between alcohol and head injury and its effect on the conscious level. Br J Surg 63: 128-130.
31. Dubowski KM (1980) Alcohol determination in the clinical laboratory. Am J Clin Pathol 74: 747.
32. Yost DA (2002) Acute care for alcohol intoxication. Postgrad Med 112: 14-26.