Epstein-Barr Virus-Associated Smooth Muscle Tumor of the Larynx: Report of a Rare Case Mimicking Leiomyosarcoma

Head and Neck Pathology

Volumn 4, Issue 4, 2010, Pages 300-304

  Huang, Jingxiang ^a   Loh, Kwok Seng ^a   Petersson, Fredrik ^a  

^a NATIONAL UNIVERSITY HEALTH SYSTEM   (Singapore)

Author keywords

EBV; Epstein Barr Virus associated smooth muscle tumour; Larynx; Leiomyosarcoma

Indexed keywords

ARTICLE; BIOPSY; CASE REPORT; COMPUTER ASSISTED TOMOGRAPHY; DIFFERENTIAL DIAGNOSIS; EPSTEIN BARR VIRUS INFECTION; HUMAN; KIDNEY TRANSPLANTATION; LARYNX; LARYNX TUMOR; LEIOMYOSARCOMA; MALE; MIDDLE AGED; PATHOLOGY; RADIOGRAPHY; SMOOTH MUSCLE; VIROLOGY;

BIOPSY; DIAGNOSIS, DIFFERENTIAL; EPSTEIN-BARR VIRUS INFECTIONS; HUMANS; KIDNEY TRANSPLANTATION; LARYNGEAL NEOPLASMS; LARYNX; LEIOMYOSARCOMA; MALE; MIDDLE AGED; MUSCLE, SMOOTH; TOMOGRAPHY, X-RAY COMPUTED;

EID: 78650065724     PISSN: 1936055X     EISSN: 19360568     Source Type: Journal    
DOI: 10.1007/s12105-010-0201-7     Document Type: Article

References (17)

1. McKiernan DC, Watters GW. Smooth muscle tumours of the larynx. J Laryngol Otol. 1995; 109: 77-9.
2. Goda JS, Saravanan K, Vashistha RK, et al. Leiomyosarcoma of the larynx: case report and review of the literature. Ear Nose Throat J. 2008; 87: 283-7.
3. Rimmer J, Giddings CE, Mady S. Leiomyosarcoma of the larynx. J Laryngol Otol. 2006; 120: e3.
4. Xu Y, Zhou S, Wang S. Vascular leiomyoma of the larynx: a rare entity. Three case reports and literature review. ORL J Otorhinolaryngol Relat Spec. 2008; 70: 264-7.
5. Gan EC, Lau DP, Chuah KL. Epstein-Barr virus-associated smooth muscle tumour mimicking bilateral vocal process granuloma. J Laryngol Otol. 2008; 122: 100-4.
6. Deyrup AT, Lee VK, Hill CE, et al. Epstein-Barr virus-associated smooth muscle tumors are distinctive mesenchymal tumors reflecting multiple infection events: a clinicopathologic and molecular analysis of 29 tumors from 19 patients. Am J Surg Pathol. 2006; 30: 75-82.
7. Rezk SA, Weiss LM. Epstein-Barr virus-associated lymphoproliferative disorders. Hum Pathol. 2007; 38: 1293-304.
8. Klein G, Giovanella BC, Lindahl T, et al. Direct evidence for the presence of Epstein-Barr virus DNA and nuclear antigen in malignant epithelial cells from patients with poorly differentiated carcinoma of the nasopharynx. Proc Natl Acad Sci USA. 1974; 71: 4737-41.
9. Pathmanathan R, Prasad U, Sadler R, et al. Clonal proliferations of cells infected with Epstein-Barr virus in preinvasive lesions related to nasopharyngeal carcinoma. N Engl J Med. 1995; 333: 693-8.
10. Lee ES, Locker J, Nalesnik M, et al. The association of Epstein-Barr virus with smooth-muscle tumors occurring after organ transplantation. N Engl J Med. 1995; 332: 19-25.
11. McClain KL, Leach CT, Jenson HB, et al. Association of Epstein-Barr virus with leiomyosarcomas in children with AIDS. N Engl J Med. 1995; 332: 12-8.
12. Rogatsch H, Bonatti H, Menet A, et al. Epstein-Barr virus-associated multicentric leiomyosarcoma in an adult patient after heart transplantation: case report and review of the literature. Am J Surg Pathol. 2000; 24: 614-21.
13. Fernandez MP, Krejci-Manwaring J, Davis TL. Epstein-Barr virus is not associated with angioleiomyomas, or other cutaneous smooth muscle tumors in immunocompetent individuals. J Cutan Pathol. 2010; 37: 507-10.
14. Volker HU, Scheich M, Zettl A, et al. Laryngeal inflammatory myofibroblastic tumors: different clinical appearance and histomorphologic presentation of one entity. Head Neck. 2009. doi: 10. 1002/hed. 21232.
15. Marioni G, Staffieri C, Marino F, et al. Leiomyosarcoma of the larynx: critical analysis of the diagnostic role played by immunohistochemistry. Am J Otolaryngol. 2005; 26: 201-6.
16. Coffin CM, Watterson J, Priest JR, et al. Extrapulmonary inflammatory myofibroblastic tumor (inflammatory pseudotumor). A clinicopathologic and immunohistochemical study of 84 cases. Am J Surg Pathol. 1995; 19: 859-72.
17. Griffin CA, Hawkins AL, Dvorak C, et al. Recurrent involvement of 2p23 in inflammatory myofibroblastic tumors. Cancer Res. 1999; 59: 2776-80.