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Volumn 11, Issue 1, 2011, Pages 99-108

Immunotherapy for metastatic prostate cancer: Where are we at with sipuleucel-T?

Author keywords

APC8015; cancer vaccine; immunotherapy; prostate cancer; provenge; sipuleucel T

Indexed keywords

ACID PHOSPHATASE PROSTATE ISOENZYME; ACID PHOSPHATASE PROSTATE ISOENZYME ANTIBODY; ANDROGEN; ANTINEOPLASTIC AGENT; BEVACIZUMAB; CANCER VACCINE; CD14 ANTIGEN; CD19 ANTIGEN; DOCETAXEL; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HYBRID PROTEIN; HYDRAZINE SULFATE; INTERCELLULAR ADHESION MOLECULE 1; KETOCONAZOLE; LACTATE DEHYDROGENASE; PA 2024; PLACEBO; PREDNISONE; PROSTATE SPECIFIC ANTIGEN; PROTEIN ANTIBODY; PROVENGE; SURAMIN; UNCLASSIFIED DRUG;

EID: 78650055750     PISSN: 14712598     EISSN: None     Source Type: Journal    
DOI: 10.1517/14712598.2011.538677     Document Type: Review
Times cited : (6)

References (28)
  • 1
    • 78650041098 scopus 로고    scopus 로고
    • SEER stat fact sheets - cancer of the prostate. National Cancer Institute, Bethesda, MD;Available from:[Last accessed 8 November 2010]
    • SEER stat fact sheets - cancer of the prostate. National Cancer Institute, Bethesda, MD; 2010. Available from: Http://seer.cancer.gov/statfacts/ html/ prost.html. [Last accessed 8 November 2010]
    • (2010)
  • 2
    • 78650047109 scopus 로고    scopus 로고
    • CancerStats key facts on cancer. Cancer research UK, London, UK,Available from:[Last accessed 8 November 2010]
    • CancerStats key facts on cancer. Cancer research UK, London, UK; 2010. Available from: Http://info. cancerresearchuk.org/cancerstats/keyfacts/ index.htm. [Last accessed 8 November 2010]
    • (2010)
  • 3
    • 78650042079 scopus 로고    scopus 로고
    • Canadian cancer statistics. Canadian Cancer Society, Toronto: Ontario 2010. Available from:[Last accessed 8 November 2010]
    • Canadian cancer statistics. Canadian Cancer Society, Toronto: Ontario 2010. Available from: Http://www.cancer. ca/canada-wide/about cancer/cancer statistics/Canadian cancer statistics.aspx? sc-lang=en. [Last accessed 8 November 2010]
  • 4
    • 0032497522 scopus 로고    scopus 로고
    • Bilateral orchiectomy with or without flutamide for metastatic prostate cancer
    • Eisenberger MA, Blumenstein BA, Crawford ED, et al. Bilateral orchiectomy with or without flutamide for metastatic prostate cancer. N Engl J Med 1998;339:1036-42
    • (1998) N Engl J Med , vol.339 , pp. 1036-1042
    • Eisenberger, M.A.1    Blumenstein, B.A.2    Crawford, E.D.3
  • 5
    • 4744337716 scopus 로고    scopus 로고
    • Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer
    • Petrylak DP, Tangen CM, Hussain MH, et al. Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer. N Engl J Med 2004;351:1513-20
    • (2004) N Engl J Med , vol.351 , pp. 1513-1520
    • Petrylak, D.P.1    Tangen, C.M.2    Hussain, M.H.3
  • 6
    • 4744366279 scopus 로고    scopus 로고
    • Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer
    • Tannock IF, de Wit R, Berry WR, et al. Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer. N Engl J Med 2004;351:1502-12
    • (2004) N Engl J Med , vol.351 , pp. 1502-1512
    • Tannock, I.F.1    De Wit, R.2    Berry, W.R.3
  • 8
    • 0034554863 scopus 로고    scopus 로고
    • Immunotherapy of hormone-refractory prostate cancer with antigen-loaded dendritic cells
    • Small EJ, Fratesi P, Reese DM, et al. Immunotherapy of hormone-refractory prostate cancer with antigen-loaded dendritic cells. J Clin Oncol 2000;18:3894-903
    • (2000) J Clin Oncol , vol.18 , pp. 3894-3903
    • Small, E.J.1    Fratesi, P.2    Reese, D.M.3
  • 9
    • 0034043167 scopus 로고    scopus 로고
    • Priming tissue-specific cellular immunity in a Phase I trial of autologous dendritic cells for prostate cancer
    • Burch PA, Breen JK, Buckner JC, et al. Priming tissue-specific cellular immunity in a Phase I trial of autologous dendritic cells for prostate cancer. Clin Cancer Res 2000;6:2175-82
    • (2000) Clin Cancer Res , vol.6 , pp. 2175-2182
    • Burch, P.A.1    Breen, J.K.2    Buckner, J.C.3
  • 10
    • 2342576353 scopus 로고    scopus 로고
    • Route of administration influences the antitumor effects of bone marrow-derived dendritic cells engineered to produce interleukin-12 in a metastatic mouse prostate cancer model
    • Saika T, Satoh T, Kusaka N, et al. Route of administration influences the antitumor effects of bone marrow-derived dendritic cells engineered to produce interleukin-12 in a metastatic mouse prostate cancer model. Cancer Gene Ther 2004;11:317-24
    • (2004) Cancer Gene Ther , vol.11 , pp. 317-324
    • Saika, T.1    Satoh, T.2    Kusaka, N.3
  • 11
    • 33745304967 scopus 로고    scopus 로고
    • Combination immunotherapy with prostatic acid phosphatase pulsed antigen-presenting cells (provenge) plus bevacizumab in patients with serologic progression of prostate cancer after definitive local therapy
    • Rini BI, Weinberg V, Fong L, et al. Combination immunotherapy with prostatic acid phosphatase pulsed antigen-presenting cells (provenge) plus bevacizumab in patients with serologic progression of prostate cancer after definitive local therapy. Cancer 2006;107:67-74
    • (2006) Cancer , vol.107 , pp. 67-74
    • Rini, B.I.1    Weinberg, V.2    Fong, L.3
  • 12
    • 0028289244 scopus 로고
    • Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha
    • Sallusto F, Lanzavecchia A. Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha. J Exp Med 1994;179:1109-18
    • (1994) J Exp Med , vol.179 , pp. 1109-1118
    • Sallusto, F.1    Lanzavecchia, A.2
  • 13
    • 0034658319 scopus 로고    scopus 로고
    • Comparative analysis of genetically modified dendritic cells and tumor cells as therapeutic cancer vaccines
    • Klein C, Bueler H, Mulligan RC. Comparative analysis of genetically modified dendritic cells and tumor cells as therapeutic cancer vaccines. J Exp Med 2000;191:1699-708
    • (2000) J Exp Med , vol.191 , pp. 1699-1708
    • Klein, C.1    Bueler, H.2    Mulligan, R.C.3
  • 14
    • 3242747658 scopus 로고    scopus 로고
    • Immunotherapy (APC8015, provenge) targeting prostatic acid phosphatase can induce durable remission of metastatic androgen-independent prostate cancer: A Phase 2 trial
    • Burch PA, Croghan GA, Gastineau DA, et al. Immunotherapy (APC8015, provenge) targeting prostatic acid phosphatase can induce durable remission of metastatic androgen-independent prostate cancer: A Phase 2 trial. Prostate 2004;60:197-204
    • (2004) Prostate , vol.60 , pp. 197-204
    • Burch, P.A.1    Croghan, G.A.2    Gastineau, D.A.3
  • 15
    • 0015835236 scopus 로고
    • Induction of hapten-specific B cell tolerance by low doses of hapten-carrier conjugate
    • Taussig MJ. Induction of hapten-specific B cell tolerance by low doses of hapten-carrier conjugate. Nature 1973;245:34-6
    • (1973) Nature , vol.245 , pp. 34-36
    • Taussig, M.J.1
  • 16
    • 22544458183 scopus 로고    scopus 로고
    • Antigen-presenting cells 8015 (provenge) in patients with androgen-dependent, biochemically relapsed prostate cancer
    • Beinart G, Rini BI, Weinberg V, Small EJ. Antigen-presenting cells 8015 (provenge) in patients with androgen-dependent, biochemically relapsed prostate cancer. Clin Prostate Cancer 2005;4:55-60
    • (2005) Clin Prostate Cancer , vol.4 , pp. 55-60
    • Beinart, G.1    Rini, B.I.2    Weinberg, V.3    Small, E.J.4
  • 17
    • 33746012881 scopus 로고    scopus 로고
    • Placebo-controlled Phase III trial of immunologic therapy with sipuleucel-T (APC8015) in patients with metastatic, asymptomatic hormone refractory prostate cancer
    • Small EJ, Schellhammer PF, Higano CS, et al. Placebo-controlled Phase III trial of immunologic therapy with sipuleucel-T (APC8015) in patients with metastatic, asymptomatic hormone refractory prostate cancer. J Clin Oncol 2006;24:3089-94
    • (2006) J Clin Oncol , vol.24 , pp. 3089-3094
    • Small, E.J.1    Schellhammer, P.F.2    Higano, C.S.3
  • 18
    • 68549135290 scopus 로고    scopus 로고
    • Integrated data from 2 randomized, double-blind, placebo-controlled, Phase 3 trials of active cellular immunotherapy with sipuleucel-T in advanced prostate cancer
    • Higano CS, Schellhammer PF, Small EJ, et al. Integrated data from 2 randomized, double-blind, placebo-controlled, Phase 3 trials of active cellular immunotherapy with sipuleucel-T in advanced prostate cancer. Cancer 2009;115:3670-9
    • (2009) Cancer , vol.115 , pp. 3670-3679
    • Higano, C.S.1    Schellhammer, P.F.2    Small, E.J.3
  • 20
    • 77955066199 scopus 로고    scopus 로고
    • Sipuleucel-T immunotherapy for castration-resistant prostate cancer
    • Kantoff PW, Higano CS, Shore N, et al. Sipuleucel-T immunotherapy for castration-resistant prostate cancer. N Engl J Med 2010;363:411-22
    • (2010) N Engl J Med , vol.363 , pp. 411-422
    • Kantoff, P.W.1    Higano, C.S.2    Shore, N.3
  • 21
    • 78650062374 scopus 로고    scopus 로고
    • Dendreon Announces FDA Advisory Committee Reviewed Provenge® for Hormone Refractory Prostate Cancer. Seattle, Denderon Corp., Washington;Available from:[Last accessed 8 November 2010]
    • Dendreon Announces FDA Advisory Committee Reviewed Provenge® for Hormone Refractory Prostate Cancer. Seattle, Denderon Corp., Washington; 2007. Available from: Http://investor. dendreon.com/phoenix.zhtml? c=120739&p=irol-newsArticle&ID=1369743&highlight=Provenge [Last accessed 8 November 2010]
    • (2007)
  • 22
    • 78650050299 scopus 로고    scopus 로고
    • Provenge (sipuleucel-T) active cellular immunotherapy treatment of metastatic prostate cancer after failing hormone therapy. ClinicalTrials.gov, Bethesda, MD;Available from:[Last accessed 8 November 2010]
    • Provenge (sipuleucel-T) active cellular immunotherapy treatment of metastatic prostate cancer after failing hormone therapy. ClinicalTrials.gov, Bethesda, MD; 2010. Available from: Http:// clinicaltrials.gov/ct2/show/ NCT00065442?term= NCT00065442&rank=1 [Last accessed 8 November 2010]
    • (2010)
  • 23
    • 78650050086 scopus 로고    scopus 로고
    • Open label study of sipuleucel-T. ClinicalTrials.gov, Bethesda, MD,Available from:[Last accessed 8 November 2010]
    • Open label study of sipuleucel-T. ClinicalTrials.gov, Bethesda, MD; 2010. Available from: Http://www. clinicaltrials.gov/ct2/show/ NCT00901342?term= dendreon&rank=5. [Last accessed 8 November 2010]
    • (2010)
  • 24
    • 78650040875 scopus 로고    scopus 로고
    • To evaluate sipuleucel-T manufactured with different concentrations of PA2024 antigen. ClinicalTrials.gov, Bethesda, MD,Available from:[Last accessed 8 November 2010]
    • To evaluate sipuleucel-T manufactured with different concentrations of PA2024 antigen. ClinicalTrials.gov, Bethesda, MD; 2010. Available from: Http://clinicaltrials. gov/ct2/show/NCT00715078. [Last accessed 8 November 2010]
    • (2010)
  • 25
    • 78650052819 scopus 로고    scopus 로고
    • Sipuleucel-T as neoadjuvant treatment in prostate cancer. ClinicalTrials.gov, Bethesda, MD;Available from:[Last accessed 8 November 2010]
    • Sipuleucel-T as neoadjuvant treatment in prostate cancer. ClinicalTrials.gov, Bethesda, MD; 2010. Available from: Http://clinicaltrials. gov/ct2/show/NCT00715104? term=NCT00715104&rank=1 [Last accessed 8 November 2010]
    • (2010)
  • 26
    • 78650047525 scopus 로고    scopus 로고
    • Provenge (TM) for the treatment of hormone sensitive prostate cancer. ClinicalTrials.gov, Bethesda, MD,Available from
    • Provenge (TM) for the treatment of hormone sensitive prostate cancer. ClinicalTrials.gov, Bethesda, MD; 2010. Available from: Http://clinicaltrials. gov/ct2/show/NCT00779402? term=Provenge+%28TM%29+for+the +treatment+of+hormone+sensitive +prostate+cancer.&rank=1
    • (2010)
  • 27
    • 58849123742 scopus 로고    scopus 로고
    • Randomized trial of active cellular immunotherapy with sipuleucel-T in androgen dependent prostate cancer (ADPC)
    • 2007 ASCO Annual Meeting Proceedings
    • Beer TM, Bernstein GT, Corman JM, et al. Randomized trial of active cellular immunotherapy with sipuleucel-T in androgen dependent prostate cancer (ADPC). 2007 ASCO Annual Meeting Proceedings. J Clin Oncol 2007;25(18S):5059
    • (2007) J Clin Oncol , vol.25 , Issue.18 S , pp. 5059
    • Beer, T.M.1    Bernstein, G.T.2    Corman, J.M.3
  • 28
    • 78650060278 scopus 로고    scopus 로고
    • Dendreon Presents Updated IMPACT Results Confirming PROVENGE Improves Overall Survival in Patients With Metastatic Castrate-Resistant Prostate Cancer. Seattle, Denderon Corp., Washington;Available from:[Last accessed 8 November 2010]
    • Dendreon Presents Updated IMPACT Results Confirming PROVENGE Improves Overall Survival in Patients With Metastatic Castrate-Resistant Prostate Cancer. Seattle, Denderon Corp., Washington; 2007. Available from: Http://investor. dendreon.com/phoenix.zhtml? c=120739&p=irolnewsArticle&ID= 1398598&highlight=. [Last accessed 8 November 2010]
    • (2007)


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