ELPylated anti-human TNF therapeutic single-domain antibodies for prevention of lethal septic shock

Plant Biotechnology Journal

Volumn 9, Issue 1, 2011, Pages 22-31

  Conrad, Udo ^a   Plagmann, Ingo ^b   Malchow, Sven ^b   Sack, Markus ^c   Floss, Doreen M ^b   Kruglov, Andrei A ^d   Nedospasov, Sergei A ^d,e   Rose John, Stefan ^b   Scheller, Jürgen ^b  

^a LEIBNIZ INSTITUTE OF PLANT GENETICS AND CROP PLANT RESEARCH IPK   (Germany)

^b UNIVERSITY OF KIEL   (Germany)

^c RWTH AACHEN UNIVERSITY   (Germany)

^d DEUTSCHES RHEUMA FORSCHUNGSZENTRUM   (Germany)

^e ENGELHARDT INSTITUTE OF MOLECULAR BIOLOGY   (Russian Federation)

Author keywords

Elastin like polypeptides; Nanobody; Sepsis; Transgenic plants; Tumour necrosis factor; VHH

Indexed keywords

ELASTIN; GALACTOSE; HYBRID PROTEIN; LIPOPOLYSACCHARIDE; MONOCLONAL ANTIBODY; PEPTIDE; TNF PROTEIN, HUMAN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL; ARTICLE; CHEMICALLY INDUCED DISORDER; DISEASE MODEL; DRUG ANTAGONISM; ESCHERICHIA COLI; GENE EXPRESSION; GENETICS; HUMAN; IMMUNOLOGY; ISOLATION AND PURIFICATION; L CELL; MOUSE; SEPTIC SHOCK; TOBACCO; TRANSGENIC PLANT;

ANIMALS; ANTIBODIES, MONOCLONAL; DISEASE MODELS, ANIMAL; ELASTIN; ESCHERICHIA COLI; GALACTOSE; GENE EXPRESSION; HUMANS; L CELLS (CELL LINE); LIPOPOLYSACCHARIDES; MICE; PEPTIDES; PLANTS, GENETICALLY MODIFIED; RECOMBINANT FUSION PROTEINS; SHOCK, SEPTIC; TOBACCO; TUMOR NECROSIS FACTOR-ALPHA;

CAMELIDAE; MUS; NICOTIANA OBTUSIFOLIA;

EID: 78650043042     PISSN: 14677644     EISSN: 14677652     Source Type: Journal    
DOI: 10.1111/j.1467-7652.2010.00523.x     Document Type: Article

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