Association between subclinical hypothyroidism and proliferative diabetic retinopathy in type 2 diabetic patients: A case-control study

Tohoku Journal of Experimental Medicine

Volumn 222, Issue 4, 2010, Pages 303-310

  Yang, Guang Ran ^a   Yang, Jin Kui ^a   Zhang, Lin ^a   An, Yan Hua ^a   Lu, Jing Kai ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

Egf; Glioma; Meta analysis; Polymorphism; Risk

Indexed keywords

ALBUMIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; THYROTROPIN;

ADULT; ARTICLE; BLOOD PRESSURE MEASUREMENT; CASE CONTROL STUDY; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DIABETIC RETINOPATHY; DISEASE ASSOCIATION; DISEASE DURATION; FEMALE; HUMAN; HYPOTHYROIDISM; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; RISK ASSESSMENT; THYROID FUNCTION TEST; URINARY EXCRETION;

CASE-CONTROL STUDIES; CHINA; DIABETES MELLITUS, TYPE 2; DIABETIC RETINOPATHY; FEMALE; HUMANS; HYPOTHYROIDISM; MALE; MIDDLE AGED; ODDS RATIO; PREVALENCE;

EID: 78650040533     PISSN: 00408727     EISSN: 13493329     Source Type: Journal    
DOI: 10.1620/tjem.222.303     Document Type: Article

References (38)

1. American Diabetes Association. (2008) Standards of medical care in diabetes-2008. Diabetes Care, 31 suppl 1, S12-S54.
2. Baloch, Z., Carayon, P., Conte-Devolx, B., Demers, L.M., Feldt-Rasmussen, U., Henry, J.F., LiVosli, V.A., Niccoli-Sire, P., John, R., Ruf, J., Smyth, P.P., Spencer, C.A. & Stockigt, J.R. Guidelines Committee, National Academy of Clinical Bio-chemi stry (2003) Laboratory medicine practice guidelines. Laboratory support for the diagnosis and monitoring of thyroid disease. Thyroid, 13, 3-126.
3. Barnett, A.H., Dixon, A.N., Bellary, S., Hanif, M.W., O'hare, J.P., Raymond, N.T. & Kumar, S. (2006) Type 2 diabetes and cardiovascular risk in the UK south Asian community. Diabeto-logia, 49, 2234-2246.
4. Beeram, M.R. & Wilson, D.P. (2000) Hypothyroxinemia of prematurity: rite of passage or therapeutic necessity? Tex. Med., 96, 60-63.
5. Berkowitz, B.A., Luan, H. & Roberts, R.L. (2004) Effect of methylimidazole-induced hypothyroidism in a model of low retinal neovascular incidence. Invest. Ophthalmol. Vis. Sci., 45, 919-921.
6. Bindels, A.J., Westendorp, R.G., Frölich, M., Seidell, J.C., Blokstra, A. & Smelt, A.H. (1999) The prevalence of subclin-ical hypothyroidism at different total plasma cholesterol levels in middle aged men and women: a need for case-finding? Clin. Endocrinol. (Oxf), 50, 217-220.
7. Biondi, B., Palmieri, E.A., Lombardi, G. & Fazio, S. (2002) Effects of subclinical thyroid dysfunction on the heart. Ann. Intern. Med., 137, 904-914.
8. Canaris, G.J., Manowitz, N.R., Mayor, G. & Ridgway, E.C. (2000) The Colorado thyroid disease prevalence study. Arch. Intern. Med., 160, 526-534.
9. Caraccio, N., Ferrannini, E. & Monzani, F. (2002) Lipoprotein profile in subclinical hypothyroidism: response to levothy-roxine replacement, a randomized placebo- controlled study. J. Clin. Endocrinol. Metab., 87, 1533-1538.
10. Chen, H.S., Wu, T.E., Jap, T.S., Lu, R.A., Wang, M.L., Chen, R.L. & Lin, H.D. (2007) Subclinical hypothyroidism is a risk factor for nephropathy and cardiovascular diseases in Type 2 diabetic patients. Diabet. Med., 24, 1336-1344.
11. Chubb, S.A., Davis, W.A. & Davis, T.M. (2005) Interactions among thyroid function, insulin sensitivity, and serum lipid concentrations: the Fremantle diabetes study. J. Clin. Endo-crinol. Metab., 90, 5317-5320.
12. Efstathiadou, Z., Bitsis, S., Milionis, H.J., Kukuvitis, A., Bairaktari, E.T., Elisaf, M.S. & Tsatsoulis, A. (2001) Lipid profle in sub-clinical hypothyroidism: is L-thyroxine substitution benefcial? Eur. J. Endocrinol., 145, 705-710.
13. Feely, J. & Isles, T.E. (1979) Screening for thyroid dysfunction in diabetics. Br. Med. J., 1, 1678.
14. Fisher, D.A. (1990) Euthyroid low thyroxine (T4) and tri iod othy-ronine (T3) states in prematures and sick neonates. Pediatr. Clin. North Am., 37, 1297-1312.
15. Gilles, R., den Heijer, M., Ross, A.H., Sweep, F.C., Hermus, A.R. & Wetzels, J.F. (2008) Thyroid function in patients with pro-teinuria. Neth. J. Med., 66, 483-485.
16. Hak, A.E., Pols, H.A., Visser, T.J., Drexhage, H.A., Hofman, A. & Witteman, J.C. (2000) Subclinical hypothyroidism is an independent risk factor for atherosclerosis and myocardial infarction in elderly women: the Rotterdam Study. Ann. Intern. Med., 132, 270-278.
17. Helfand, M. & Redfern, C.C. (1998) Clinical guideline, part 2. Screening for thyroid disease: an update. American College of Physicians. Ann. Intern. Med., 129, 144-158.
18. Helfand, M.; U.S. Preventive Services Task Force (2004) Screening for subclinical thyroid dysfunction in nonpregnant adults: a summary of the evidence for the U.S. Preventive Services Task Force. Ann. Intern. Med., 140, 128-141.
19. Hollowell, J.G., Staehling, N.W., Flanders, W.D., Hannon, W.H., Gunter, E.W., Spencer, C.A. & Braverman, L.E. (2002) Serum TSH, T(4), and thyroid antibodies in the United States population (1988 to 1994): National Health and Nutrition Examination Survey (NHANES III). J. Clin. Endocrinol. Metab., 87, 489-499.
20. Kanaya, A.M., Harris, F., Volpato, S., Pérez-Stable, E.J., Harris, T. & Bauer, D.C. (2002) Association between thyroid dysfunction and total cholesterol level in an older biracial population: the health, aging and body composition study. Arch. Intern. Med., 162, 773-779.
21. Kirsten, D. (2000) The thyroid gland: physiology and patho physiology. Neonatal Netw., 19, 11-26.
22. Maratou, E., Hadjidakis, D.J., Kollias, A., Tsegka, K., Peppa, M., Alevizaki, M., Mitrou, P., Lambadiari, V., Boutati, E., Nikzas, D., Tountas, N., Economopoulos, T., Raptis, S.A. & Dimitriadis, G. (2009) Studies of insulin resistance in patients with clinical and subclinical hypothyroidism. Eur. J. Endo- crinol., 160, 785-790.
23. Meier, C., Staub, J.J., Roth, C.B., Guglielmetti, M., Kunz, M., Miserez, A.R., Drewe, J., Huber, P., Herzog, R. & Müller, B. (2001) TSH-controlled L-thyroxine therapy reduces cholesterol levels and clinical symptoms in subclinical hypothy-roidism: a double blind, placebo-controlled trial (Basel Thyroid Study). J. Clin. Endocrinol. Metab., 86, 4860-4866.
24. Monzani, F., Caraccio, N., Kozàkowà, M., Dardano, A., Vittone, F., Virdis, A., Taddei, S., Palombo, C. & Ferrannini, E. (2004) Effect of levothyroxine replacement on lipid profile and intima-media thickness in subclinical hypothyroidism: a double-blind, placebo-controlled study. J. Clin. Endocrinol. Metab., 89, 2099-2106.
25. Mookadam, M., Leske, D.A., Fautsch, M.P., Lanier, W.L. & Holmes, J.M. (2004) The anti-thyroid drug methimazole induces neovascularization in the neonatal rat analogous to ROP. Invest. Ophthalmol. Vis. Sci., 45, 4145-4150.
26. Mutapcic, L., Wren, S.M., Leske, D.A., Fautsch, M.P. & Holmes, J.M. (2005) The effect of L-thyroxine supplementation on retinal vascular development in neonatal rats. Curr. Eye Res., 30, 1035-1040.
27. Perros, P., McCrimmon, R.J., Shaw, G. & Frier, B.M. (1995) Frequency of thyroid dysfunction in diabetic patients: value of annual screening. Diabet. Med., 12, 622-627.
28. Pirich, C., Müllner, M. & Sinzinger, H. (2000) Prevalence and relevance of thyroid dysfunction in 1922 cholesterol screening participants. J. Clin. Epidemiol., 53, 623-629.
29. Rodondi, N., den Elzen, W.P., Bauer, D.C., Cappola, A.R., Razvi, S., Walsh, J.P., Asvold, B.O., Iervasi, G., Imaizumi, M., Collet, T.H., Bremner, A., Maisonneuve, P., Sgarbi, J.A., Khaw, K.T., Vanderpump, M.P., Newman, A.B., Cornuz, J., Franklyn, J.A., Westendorp, R.G., Vittinghoff, E. & Gussekloo, J.; Thyroid Studies Collaboration. (2010) Subclinical hypothyroidism and the risk of coronary heart disease and mortality. JAMA, 304, 1365-1374.
30. Smithson, M.J. (1998) Screening for thyroid dysfunction in a community population of diabetic patients. Diabet. Med., 15, 148-150.
31. Stratton, I.M., Kohner, E.M., Aldington, S.J., Turner, R.C., Holman, R.R., Manley, S.E. & Matthews, D.R. (2001) UKPDS 50: risk factors for incidence and progression of retinopathy in Type II diabetes over 6 years from diagnosis. Diabetologia, 44, 156-163.
32. Taddei, S., Caraccio, N., Virdis, A., Dardano, A., Versari, D., Ghiadoni, L., Salvetti, A., Ferrannini, E. & Monzani, F. (2003) Impaired endothelium-dependent vasodilatation in subclinical hypothyoidism: benefcial effect of levothyroxine therapy. J. Clin. Endocrinol. Metab., 88, 3731-3737.
33. Tilton, R.G., Pugliese, G., Chang, K., Speedy, A., Province, M.A., Kilo, C. & Williamson, J.R. (1989) Effects of hypothyroidism on vascular 125I-albumin permeation and blood fow in rats. Metabolism, 38, 471-478.
34. Tsimihodimos, V., Bairaktari, E., Tzallas, C., Miltiadus, G., Liberopoulos, E. & Elisaf, M. (1999) The incidence of thyroid function abnormalities in patients attending an outpatient lipid clinic. Thyroid, 9, 365-368.
35. Tzotzas, T., Krassas, G.E., Konstantinidis, T. & Bougoulia, M. (2000) Changes in lipoprotein (a) levels in overt and subclin-ical hypothyroidism before and during treatment. Thyroid, 10, 803-808.
36. Uzunlulu, M., Yorulmaz, E. & Oguz, A. (2007) Prevalence of sub-clinical hypothyroidism in patients with metabolic syndrome. Endocr. J., 54, 71-76.
37. Vierhapper, H., Nardi, A., Grösser, P., Raber, W. & Gessl, A. (2000) Low-density lipoprotein cholesterol in subclinical hypothy-roidism. Thyroid, 10, 981-984.
38. Yang, J.K., Liu, W., Shi, J. & Li, Y.B. (2010) An association between subclinical hypothyroidism and sight-threatening diabetic retinopathy in type 2 diabetic patients. Diabetes Care, 33, 1018-1020.