The American Heart Association advisory on n-6 fatty acids: Evidence based or biased evidence?

British Journal of Nutrition

Volumn 104, Issue 11, 2010, Pages 1575-1576

  Calder, Philip C ^a  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARACHIDONIC ACID; CHOLESTEROL; LINOLEIC ACID; LOW DENSITY LIPOPROTEIN; OMEGA 3 FATTY ACID; OMEGA 6 FATTY ACID; POLYUNSATURATED FATTY ACID;

ATHEROSCLEROTIC PLAQUE; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CHOLESTEROL BLOOD LEVEL; CONGENITAL HEART DISEASE; DIETARY INTAKE; DIETARY REFERENCE INTAKE; EVIDENCE BASED MEDICINE; FAT INTAKE; FATTY ACID METABOLISM; HUMAN; MEDICAL SOCIETY; NONHUMAN; NOTE; RISK FACTOR; RISK REDUCTION; SYSTEMATIC ERROR;

AMERICAN HEART ASSOCIATION; CORONARY DISEASE; DIETARY FATS; EVIDENCE-BASED MEDICINE; FATTY ACIDS, OMEGA-3; FATTY ACIDS, OMEGA-6; GUIDELINES AS TOPIC; HUMANS; LINOLEIC ACID; UNITED STATES;

EID: 78650029111     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1017/S0007114510004253     Document Type: Note

References (18)

1. Burr GO & Burr MM (1929) A new deficiency disease produced by the rigid exclusion of fat from the diet. J Biol Chem 82, 345-367.
2. Burr GO & Burr MM (1930) The nature and role of the fatty acids essential in nutrition. J Biol Chem 86, 587-621.
3. Pudelkewicz C, Seufert J & Holman RT (1968) Requirements of the female rat for linoleic and linolenic acids. J Nutr 94, 138-146.
4. Holman RT, Johnson SB & Hatch TF (1982) A case of human linolenic acid deficiency involving neurological abnormalities. Am J. Clin Nutr 35, 617-623.
5. Katan MB, Zock PL & Mensink RP (1995) Dietary oils, serum lipoproteins, and coronary heart disease. Am J. Clin Nutr 61, 1368S-1373S.
6. Report of the Panel on DRVs of the Committee on Medical Aspects of Food Policy (COMA) of the Department of Health (1991) Dietary Reference Values (DRVs) for Food Energy and Nutrients for the UK. Report on Health and Social Subjects no. 41. London: The Stationery Office.
7. Mosfegh A, Goldman J & Cleveland L (2005) What We Eat in America, NHANES 2001-2002. Usual Nutrient Intake from Foods as Compared to Dietary Reference Intakes. Washington, DC: US Department of Agriculture, Agricultural Research Service.
8. Henderson L, Gregory J, Irving K, et al. (2003) The National Diet and Nutrition Survey: Adults Aged 19 to 64 Years - Energy, Protein, Carbohydrate, Fat and Alcohol Intake. London: The Stationery Office.
9. Tsimikas S, Philis-Tsimikas A, Alexopoulos S, et al. (1999) LDL isolated from Greek subjects on a typical diet or from American subjects on an oleate-supplemented diet induces less monocyte chemotaxis and adhesion when exposed to oxidative stress. Arterioscler Thromb Vasc Biol 19, 122-130.
10. Welsch CW (1992) Relationship between dietary fat and experimental mammary tumorigenesis: A review and critique. Cancer Res 52, 2040s-2048s.
11. Report of the Cardiovascular Review Group of the Committee on Medical Aspects of Food Policy (COMA) of the Department of Health (1994) Nutritional Aspects of Cardiovascular Disease. Report on Health and Social Subjects no. 46. London: The Stationery Office.
12. Calder PC (2004) n-3 Fatty acids and cardiovascular disease: Evidence explained and mechanisms explored. Clin Sci 107, 1-11.
13. Saravanan P, Davidson NC, Schmidt EB, et al. (2010) Cardiovascular effects of marine omega-3 fatty acids. Lancet 376, 540-550.
14. Calder PC & Yaqoob P (2009) Understanding omega-3 polyunsaturated fatty acids. Postgrad Med 121, 148-157.
15. Simopoulos AP (2002) The importance of the ratio of omega- 6/omega-3 essential fatty acids. Biomed Pharmacother 56, 365-379.
16. Lands WE (2003) Primary prevention in cardiovascular disease: Moving out of the shadows of the truth about death. Nutr Metab Cardiovasc Dis 13, 154-164.
17. Harris WS, Mozaffarian D, Rimm E, et al. (2009) n-6 fatty acids and risk for cardiovascular disease: A science advisory from the American Heart Association Nutrition Subcommittee of the Council on Nutrition. Physical Activity, and Metabolism; Council on Cardiovascular Nursing; and Council on Epidemiology and Prevention. Circulation 119, 902-907.
18. Ramsden CE, Hibbeln JR, Majchrzak SF, et al. (2010) n-6 Fatty acid-specific and mixed polyunsaturate dietary interventions have different effects on CHD risk: A meta-analysis of randomised controlled trials. Br J Nutr 104, 1586-1600.