Synbiotics reduce allergen-induced T-helper 2 response and improve peak expiratory flow in allergic asthmatics

Allergy: European Journal of Allergy and Clinical Immunology

Volumn 66, Issue 1, 2011, Pages 39-47

  Van De Pol, M A ^a   Lutter, R ^a   Smids, B S ^a   Weersink, E J M ^a   Van Der Zee, J S ^a,b  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b Onze Lieve Vrouwe Gasthuis ^*  (Netherlands)

Author keywords

allergic asthma; IL 5; randomized placebo controlled trial; synbiotics; Th2 response

Indexed keywords

ALLERGEN; ANTIHISTAMINIC AGENT; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; BIFIDOBACTERIUM BREVE EXTRACT; CORTICOSTEROID; EOSINOPHIL CATIONIC PROTEIN; FRUCTOSE OLIGOSACCHARIDE; GALACTOSE OLIGOSACCHARIDE; IMMUNOFORTIS; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 5; MYELOPEROXIDASE; PLACEBO; UNCLASSIFIED DRUG;

ALLERGIC ASTHMA; ALLERGIC REACTION; ARTICLE; BIFIDOBACTERIUM BREVE; BLINDNESS; BLOOD SAMPLING; CLINICAL ARTICLE; CLINICAL TRIAL; CONSTIPATION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CYTOKINE PRODUCTION; DIARRHEA; DOUBLE BLIND PROCEDURE; DRUG EFFECT; ENZYME LINKED IMMUNOSPOT ASSAY; EOSINOPHIL; EOSINOPHIL COUNT; FEMALE; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; FORCED EXPIRATORY VOLUME; HOUSE DUST; HOUSE DUST ALLERGY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE TEST; LUNG FUNCTION; LUNG FUNCTION TEST; MALE; NEUTROPHIL; PEAK EXPIRATORY FLOW; PERIPHERAL BLOOD MONONUCLEAR CELL; PRICK TEST; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SCORING SYSTEM; SINGLE BLIND PROCEDURE; SKIN TEST; SPUTUM; TH2 CELL; TREATMENT DURATION; TREATMENT OUTCOME;

ADOLESCENT; ADULT; ALLERGENS; ANIMALS; ASTHMA; BIFIDOBACTERIUM; BRONCHIAL PROVOCATION TESTS; CYTOKINES; DOUBLE-BLIND METHOD; FEMALE; HUMANS; HYPERSENSITIVITY, IMMEDIATE; MALE; MIDDLE AGED; OLIGOSACCHARIDES; PEAK EXPIRATORY FLOW RATE; PREBIOTICS; PROBIOTICS; PYROGLYPHIDAE; SYNBIOTICS; TH2 CELLS; TREATMENT OUTCOME; YOUNG ADULT;

EID: 78649992810     PISSN: 01054538     EISSN: 13989995     Source Type: Journal    
DOI: 10.1111/j.1398-9995.2010.02454.x     Document Type: Article

References (39)

1. Bateman ED, Hurd SS, Barnes PJ, Bousquet J, Drazen JM, FitzGerald M, et al. Global strategy for asthma management and prevention: GINA executive summary. Eur Respir J 2008; 31: 143-178.
2. Robinson DS,. The role of the mast cell in asthma: induction of airway hyperresponsiveness by interaction with smooth muscle? J Allergy Clin.Immunol 2004; 114: 58-65.
3. Hogan SP, Rosenberg HF, Moqbel R, Phipps S, Foster PS, Lacy P, et al. Eosinophils: biological properties and role in health and disease. Clin Exp Allergy 2008; 38: 709-750.
4. Larche M, Robinson DS, Kay AB,. The role of T lymphocytes in the pathogenesis of asthma. J Allergy Clin Immunol 2003; 111: 450-463.
5. Busse WW, Lemanske RF Jr,. Asthma. N Engl J Med 2001; 344: 350-362.
6. Yoo J, Tcheurekdjian H, Lynch SV, Cabana M, Boushey HA,. Microbial manipulation of immune function for asthma prevention: inferences from clinical trials. Proc Am Thorac Soc 2007; 4: 277-282.
7. Karlsson H, Hessle C, Rudin A,. Innate immune responses of human neonatal cells to bacteria from the normal gastrointestinal flora. Infect Immun 2002; 70: 6688-6696.
8. Nagler-Anderson C, Terhoust C, Bhan AK, Podolsky DK,. Mucosal antigen presentation and the control of tolerance and immunity. Trends Immunol 2001; 22: 120-122.
9. Sudo N, Yu XN, Aiba Y, Oyama N, Sonoda J, Koga Y, et al. An oral introduction of intestinal bacteria prevents the development of a long-term Th2-skewed immunological memory induced by neonatal antibiotic treatment in mice. Clin Exp Allergy 2002; 32: 1112-1116.
10. Bjorksten B, Naaber P, Sepp E, Mikelsaar M,. The intestinal microflora in allergic Estonian and Swedish 2-year-old children. Clin Exp Allergy 1999; 29: 342-346.
11. Ouwehand AC, Isolauri E, He F, Hashimoto H, Benno Y, Salminen S,. Differences in Bifidobacterium flora composition in allergic and healthy infants. J Allergy Clin Immunol 2001; 108: 144-145.
12. Ng SC, Hart AL, Kamm MA, Stagg AJ, Knight SC,. Mechanisms of action of probiotics: recent advances. Inflamm Bowel Dis 2009; 15: 300-310.
13. Borchers AT, Selmi C, Meyers FJ, Keen CL, Gershwin ME,. Probiotics and immunity. J Gastroenterol 2009; 44: 26-46.
14. Karimi K, Inman MD, Bienenstock J, Forsythe P,. Lactobacillus reuteri-induced regulatory T cells protect against an allergic airway response in mice. Am J Respir Crit Care Med 2009; 179: 186-193.
15. Kalliomaki M, Salminen S, Poussa T, Arvilommi H, Isolauri E,. Probiotics and prevention of atopic disease: 4-year follow-up of a randomised placebo-controlled trial. Lancet 2003; 361: 1869-1871.
16. Rosenfeldt V, Benfeldt E, Nielsen SD, Michaelsen KF, Jeppesen DL, Valerius NH, et al. Effect of probiotic Lactobacillus strains in children with atopic dermatitis. J Allergy Clin Immunol 2003; 111: 389-395.
17. Viljanen M, Savilahti E, Haahtela T, Juntunen-Backman K, Korpela R, Poussa T, et al. Probiotics in the treatment of atopic eczema/dermatitis syndrome in infants: a double-blind placebo-controlled trial. Allergy 2005; 60: 494-500.
18. Wheeler JG, Shema SJ, Bogle ML, Shirrell MA, Burks AW, Pittler A, et al. Immune and clinical impact of Lactobacillus acidophilus on asthma. Ann Allergy Asthma Immunol 1997; 79: 229-233.
19. Helin T, Haahtela S, Haahtela T,. No effect of oral treatment with an intestinal bacterial strain, Lactobacillus rhamnosus (ATCC 53103), on birch-pollen allergy: a placebo-controlled double-blind study. Allergy 2002; 57: 243-246.
20. Prescott SL, Bjorksten B,. Probiotics for the prevention or treatment of allergic diseases. J Allergy Clin Immunol 2007; 120: 255-262.
21. Gibson GR, Roberfroid MB,. Dietary modulation of the human colonic microbiota: introducing the concept of prebiotics. J Nutr 1995; 125: 1401-1412.
22. Noverr MC, Huffnagle GB,. The 'microflora hypothesis' of allergic diseases. Clin Exp Allergy 2005; 35: 1511-1520.
23. Moro GE, Mosca F, Miniello V, Fanaro S, Jelinek J, Stahl B, et al. Effects of a new mixture of prebiotics on faecal flora and stools in term infants. Acta Paediatr Suppl 2003; 91: 77-79.
24. Van Der Aa LB, Heymans HS, Van Aalderen WM, Sillevis Smitt JH, Knol J, Ben AK, et al. Effect of a new synbiotic mixture on atopic dermatitis in infants: a randomized-controlled trial. Clin Exp Allergy 2010; 40: 795-804.
25. Fanaro S, Boehm G, Garssen J, Knol J, Mosca F, Stahl B, et al. Galacto-oligosaccharides and long-chain fructo-oligosaccharides as prebiotics in infant formulas: a review. Acta Paediatr Suppl 2005; 94: 22-26.
26. Hougee S, Vriesema AJ, Wijering SC, Knippels LM, Folkerts G, Nijkamp FP, et al. Oral treatment with probiotics reduces allergic symptoms in ovalbumin-sensitized mice: a bacterial strain comparative study. Int Arch Allergy Immunol 2009; 151: 107-117.
27. Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease (COPD) and asthma. This official statement of the American Thoracic Society was adopted by the ATS Board of Directors, November 1986. Am Rev Respir Dis 1987; 136: 225-244.
28. Sterk PJ, Fabbri LM, Quanjer PH, Cockcroft DW, O'Byrne PM, Anderson SD, et al. Airway responsiveness. Standardized challenge testing with pharmacological, physical and sensitizing stimuli in adults. Report Working Party Standardization of Lung Function Tests, European Community for Steel and Coal. Official Statement of the European Respiratory Society. Eur Respir J Suppl 1993; 16: 53-83.
29. Van Der Veen MJ, Van Der Zee JS,. Aerosol recovery from large-volume reservoir delivery systems is highly dependent on the static properties of the reservoir. Eur Respir J 1999; 13: 668-672.
30. Nocker RE, Out TA, Weller FR, De Riemer MJ, Jansen HM, Van Der Zee JS,. Induced sputum and bronchoalveolar lavage as tools for evaluating the effects of inhaled corticosteroids in patients with asthma. J Lab Clin Med 2000; 136: 39-49.
31. Reimert CM, Venge P, Kharazmi A, Bendtzen K,. Detection of eosinophil cationic protein (ECP) by an enzyme-linked immunosorbent assay. J Immunol Methods 1991; 138: 285-290.
32. Bresser P, Out TA, Van AL, Jansen HM, Lutter R,. Airway inflammation in nonobstructive and obstructive chronic bronchitis with chronic haemophilus influenzae airway infection. Comparison with noninfected patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2000; 162: 947-952.
33. McNamee LA, Fattah DI, Baker TJ, Bains SK, Hissey PH,. Production, characterisation and use of monoclonal antibodies to human interleukin-5 in an enzyme-linked immunosorbent assay. J Immunol Methods 1991; 141: 81-88.
34. Lopuhaa CE, Out TA, Jansen HM, Aalberse RC, Van Der Zee JS,. Allergen-induced bronchial inflammation in house dust mite-allergic patients with or without asthma. Clin Exp Allergy 2002; 32: 1720-1727.
35. Kukkonen K, Savilahti E, Haahtela T, Juntunen-Backman K, Korpela R, Poussa T, et al. Probiotics and prebiotic galacto-oligosaccharides in the prevention of allergic diseases: a randomized, double-blind, placebo-controlled trial. J Allergy Clin Immunol 2007; 119: 192-198.
36. Van Der Veen MJ, Van Neerven RJ, De Jong EC, Aalberse RC, Jansen HM, Van Der Zee JS,. The late asthmatic response is associated with baseline allergen-specific proliferative responsiveness of peripheral T lymphocytes in vitro and serum interleukin-5. Clin Exp Allergy 1999; 29: 217-227.
37. Prescott SL, Dunstan JA, Hale J, Breckler L, Lehmann H, Weston S, et al. Clinical effects of probiotics are associated with increased interferon-gamma responses in very young children with atopic dermatitis. Clin Exp Allergy 2005; 35: 1557-1564.
38. Lammers KM, Brigidi P, Vitali B, Gionchetti P, Rizzello F, Caramelli E, et al. Immunomodulatory effects of probiotic bacteria DNA: IL-1 and IL-10 response in human peripheral blood mononuclear cells. FEMS Immunol Med Microbiol 2003; 38: 165-172.
39. Smits HH, Engering A, Van Der KD, De Jong EC, Schipper K, Van Capel TM, et al. Selective probiotic bacteria induce IL-10-producing regulatory T cells in vitro by modulating dendritic cell function through dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin. J Allergy Clin Immunol 2005; 115: 1260-1267.