Lactate dehydrogenase as prognostic factor in limited and extensive disease stage small cell lung cancer - A retrospective single institution analysis

Respiratory Medicine

Volumn 104, Issue 12, 2010, Pages 1937-1942

  Hermes, Andreas ^a   Gatzemeier, Ulrich ^a   Waschki, Benjamin ^a   Reck, Martin ^a  

^a KRANKENHAUS GROSSHANSDORF   (Germany)

Author keywords

LDH; Prognostic factor; Small cell lung cancer; Survival

Indexed keywords

ANTINEOPLASTIC AGENT; LACTATE DEHYDROGENASE;

ADULT; AGED; ARTICLE; BRONCHOSCOPY; CANCER CHEMOTHERAPY; CANCER STAGING; COMPUTER ASSISTED TOMOGRAPHY; CYTOLOGY; FACTUAL DATABASE; FEMALE; HISTOLOGY; HUMAN; LACTATE DEHYDROGENASE BLOOD LEVEL; LUNG SMALL CELL CANCER; MAJOR CLINICAL STUDY; MALE; OVERALL SURVIVAL; PRIORITY JOURNAL; PROGNOSIS; PROPORTIONAL HAZARDS MODEL; RETROSPECTIVE STUDY; TREATMENT RESPONSE;

ADULT; AGED; AGED, 80 AND OVER; BIOLOGICAL MARKERS; CARCINOMA, SMALL CELL; FEMALE; HUMANS; L-LACTATE DEHYDROGENASE; LUNG NEOPLASMS; MALE; MIDDLE AGED; NEOPLASM STAGING; PROGNOSIS; RETROSPECTIVE STUDIES;

EID: 78649986923     PISSN: 09546111     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.rmed.2010.07.013     Document Type: Article

References (29)

1. A. Jemal, R. Siegel, and E. Ward Cancer statistics 2008 CA Cancer J Clin 58 2008 71 96
2. B. Slotman, C. Faivre-Finn, and G. Kramer Prophylactic cranial irradiation in extensive small-cell lung cancer N Engl J Med 357 2007 664 672
3. L. Hyde, J. Wolf, and S. Mc Cracken Natural course of inoperable lung cancer Chest 64 1973 309 312
4. K.E. Stanley Prognostic factors in lung cancer J. Aisner, Lung cancer 1985 Churchill Livingstone New York, NY 41 66
5. T. Ohnoshi, S. Hiraki, and Y. Nakata Pretreatment serum albumin concentration and lactic dehydrogenase activity as prognostic factors in patients with small cell lung cancer Acta Med Okayama 36 1982 487 490
6. J.P. Sculier, R. Feld, and W.K. Evans Carcinoembryonic antigen: a useful prognostic marker in small cell lung cancer J Clin Oncol 3 1985 1349 1354
7. D.N. Carney, D.C. Ihde, and M.H. Cohen Serum neuron specific enolase: a marker for disease extent and response to therapy of small cell carcinoma Lancet 1 1982 583 585
8. T. Wang, R. Feld, and U. Sagman The combined use of LDH and CEA as independent prognostic markers for small cell lung cancer Proc Am Assoc Cancer Res 27 1986 162 abstr 641
9. H. Hagberg, and A. Siegbahn Prognostic level of serum lactic dehydrogenase in non-Hodgkin's lymphoma Scand J Haematol 31 1983 49 65
10. H.D. Brereton, R. Simon, and T.C. Pomeroy Pretreatment lactate dehydrogenase predicting metastatic spread in Ewing's sarcoma Ann Intern Med 83 1975 352 354
11. B. Simonsson, G. Grenning, and C. Kallander Prognostic level of serum lactic dehydrogenase (S-LDH) in multiple myeloma Eur J Clin Invest 17 1987 336 339
12. B. Barlogie, L. Smallwood, and T. Smith High serum levels of lactic dehydrogenase identify a high-grade lymphoma-like myeloma Ann Intern Med 110 1989 521 525
13. R.F. Schilling, B. McKnight, and J.J. Crowley Prognostic level of serum lactate dehydrogenase level in Hodgkin's disease J Lab Clin Med 99 1982 382 387
14. R.L. Souhami, J. Bradbury, and D.M. Geddes Prognostic significance of laboratory parameters measured at diagnosis in small cell carcinoma of the lung Cancer Res 45 1985 2878 2882
15. M.H. Cohen, R. Makuch, and A. Johnston-Early Laboratory parameters as an alternative to performance status in prognostic stratification of patients with small cell lung cancer Cancer Treat Rep 65 1981 187 195
16. L.H. Maurer, and T.F. Pajak Prognostic factors in small cell carcinoma of the lung: a cancer and leukemia group B study Cancer Treat Rep 65 1981 767 774
17. K. Osterlind, and P.K. Andersen Prognostic factors in small cell lung cancer: multivariate model based on 778 patients treated with chemotherapy with or without irradiation Cancer Res 46 1986 4189 4194
18. T. Cerney, V. Blair, and H. Anderson Pretreatment prognostic factors and scoring system in 407 small cell lung cancer patients Int J Cancer 39 1987 146 149
19. K.S. Albain, J.J. Crowley, and M. Le Blanc Determinants of improved outcome in small-cell lung cancer: an analysis of the 2,580-patient southwest oncology group data base J Clin Oncol 8 1990 1563 1574
20. R.W. Byhardt, A. Hartz, and J.A. Libnoch Prognostic influence of TNM staging and LDH levels in small cell carcinoma of the lung (SCCL) Int J Radiat Oncol Biol Phys 12 1986 771 777
21. M.A. Vezzoni, R. Lucchini, and R. Giardini Lactate dehydrogenase levels in cellular extracts of human malignant lymphomas Tumori 69 1983 279 282
22. P.A. Ganz, P.Y. Ma, and H.J. Wang Evaluation of three biochemical markers for serially monitoring the therapy of small cell lung cancer J Clin Oncol 5 1987 472 479
23. M.D. Vincent, S.E. Ashley, and I.A. Smith Prognostic factors in small cell lung cancer: a simple prognostic index is better than conventional staging Eur J Cancer Clin Oncol 23 1987 1589 1599
24. J.D. Hainsworth, D.H. Johnson, and R.V. Farese Limited stage small cell lung cancer: analysis of clinical prognostic factors Southampt Med J 80 1987 1518 1522
25. P. Therasse, S. Arbuck, and E.A. Eisenhauer New guidelines to evaluate the response to treatment in solid tumors J Natl Cancer Inst 92 3 2000 205 216 (Pubitemid 30099779)
26. K. Osterlind, F.R. Hirsch, and A.G. Pedersen Serum lactate dehydrogenase and bone marrow metastasis in small cell carcinoma of the lung N Engl J Med 313 1985 759
27. D.H. Johnson, and A.F. Greco Serum lactate dehydrogenase and bone marrow metastasis in small cell carcinoma of the lung N Engl J Med 313 1985 759
28. U. Sagman, R. Feld, and W.K. Evans the prognostic significance of pretreatment serum lactate dehydrogenase in patients with small cell lung cancer J Clin Oncol 9 1991 954 961
29. E.L. Kaplan, and P. Meier Non parametric estimation from incomplete observations J Am Stat Assoc 53 1958 457 481