-
1
-
-
70449503814
-
The RE-LY study: Randomized evaluation of longterm anticoagulant therapy: Dabigatran vs. warfarin
-
Camm AJ. The RE-LY study: Randomized evaluation of longterm anticoagulant therapy: Dabigatran vs. warfarin. Eur Heart J 2009; 30(21): 2554-5.
-
(2009)
Eur Heart J
, vol.30
, Issue.21
, pp. 2554-2555
-
-
Camm, A.J.1
-
2
-
-
71849117615
-
Dabigatran versus warfarin in the treatment of acute venous thromboembolism
-
Schulman S, Kearon C, Kakkar AK. Dabigatran versus warfarin in the treatment of acute venous thromboembolism. N Engl J Med 2009; 361(24): 2342-52.
-
(2009)
N Engl J Med
, vol.361
, Issue.24
, pp. 2342-2352
-
-
Schulman, S.1
Kearon, C.2
Kakkar, A.K.3
-
3
-
-
77950946483
-
New direct thrombin inhibitors
-
Squizzato A, Dentali F, Steidl L, Ageno W. New direct thrombin inhibitors. Intern Emerg Med 2009; 4(6): 455-7.
-
(2009)
Intern Emerg Med
, vol.4
, Issue.6
, pp. 455-457
-
-
Squizzato, A.1
Dentali, F.2
Steidl, L.3
Ageno, W.4
-
8
-
-
0037171819
-
Structure-based design of novel potent nonpeptide thrombin inhibitors
-
Hauel NH, Nar H, Priepke H, Ries U, Stassen JM, Wienen W. Structure-based design of novel potent nonpeptide thrombin inhibitors. J Med Chem 2002; 45: 1757-66.
-
(2002)
J Med Chem
, vol.45
, pp. 1757-1766
-
-
Hauel, N.H.1
Nar, H.2
Priepke, H.3
Ries, U.4
Stassen, J.M.5
Wienen, W.6
-
10
-
-
57449098437
-
Pharmacokinetics and pharmacodynamics of dabigatran etexilate, an oral direct thrombin inhibitor, are not affected by moderate hepatic impairment
-
Stangier J, Stähle H, Rathgen K, Roth W, Shakeri-Nejad K. Pharmacokinetics and pharmacodynamics of dabigatran etexilate, an oral direct thrombin inhibitor, are not affected by moderate hepatic impairment. J Clin Pharmacol 2008; 48(12): 1411-9.
-
(2008)
J Clin Pharmacol
, vol.48
, Issue.12
, pp. 1411-1419
-
-
Stangier, J.1
Stähle, H.2
Rathgen, K.3
Roth, W.4
Shakeri-Nejad, K.5
-
11
-
-
17644400166
-
Pharmacokinetic profile of the oral direct thrombin inhibitor dabigatran etexilate in healthy volunteers and patients undergoing total hip replacement
-
Stangier J, Eriksson BI, Dahl OE, Ahnfelt L, Nehmiz G, Stähle H, et al. Pharmacokinetic profile of the oral direct thrombin inhibitor dabigatran etexilate in healthy volunteers and patients undergoing total hip replacement. J Clin Pharmacol 2005; 45: 555-63.
-
(2005)
J Clin Pharmacol
, vol.45
, pp. 555-563
-
-
Stangier, J.1
Eriksson, B.I.2
Dahl, O.E.3
Ahnfelt, L.4
Nehmiz, G.5
Stähle, H.6
-
12
-
-
33847094672
-
Population pharmacokinetic analysis of the new oral thrombin inhibitor dabigatran etexilate (BIBR 1048) in patients undergoing primary elective total hip replacement surgery
-
Trocóniz IF, Tillmann C, Liesenfeld KH, Schäfer HG, Stangier J. Population pharmacokinetic analysis of the new oral thrombin inhibitor dabigatran etexilate (BIBR 1048) in patients undergoing primary elective total hip replacement surgery. J Clin Pharmacol 2007; 47: 371-82.
-
(2007)
J Clin Pharmacol
, vol.47
, pp. 371-382
-
-
Trocóniz, I.F.1
Tillmann, C.2
Liesenfeld, K.H.3
Schäfer, H.G.4
Stangier, J.5
-
13
-
-
4644230820
-
The pharmacology and management of the vitamin K antagonists. The Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy
-
Ansell J, Hirsh J, Poller L, Bussey H, Jacobson A, Hylek E. The pharmacology and management of the vitamin K antagonists. The Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. Chest 2004; 126 (3 Suppl): 204S-33S.
-
(2004)
Chest
, vol.126
, Issue.3 SUPPL.
-
-
Ansell, J.1
Hirsh, J.2
Poller, L.3
Bussey, H.4
Jacobson, A.5
Hylek, E.6
-
14
-
-
74949139434
-
The new oral anticoagulants
-
Garcia D, Libby E, Crowther MA. The new oral anticoagulants. Blood 2010; 115(1): 15-20.
-
(2010)
Blood
, vol.115
, Issue.1
, pp. 15-20
-
-
Garcia, D.1
Libby, E.2
Crowther, M.A.3
-
16
-
-
34548031359
-
The pharmacokinetics, pharmacodynmics and tolerability of dabigatran etexilate, a new oral direct thrombin inhibitor in healthy male subjects
-
Stangier J, Rathgen K, Staehle H, Gansser D, Roth W. The pharmacokinetics, pharmacodynmics and tolerability of dabigatran etexilate, a new oral direct thrombin inhibitor in healthy male subjects. Br J Clin Pharmacol 2007; 64: 292-303.
-
(2007)
Br J Clin Pharmacol
, vol.64
, pp. 292-303
-
-
Stangier, J.1
Rathgen, K.2
Staehle, H.3
Gansser, D.4
Roth, W.5
-
17
-
-
30544450381
-
Dabigatran/dabigatran etexilate: Prevention of DVT, prevention of ischemic stroke, thrombin inhibitor
-
Sorbera LA, Bozza J, Castaner J. Dabigatran/dabigatran etexilate: Prevention of DVT, prevention of ischemic stroke, thrombin inhibitor. Drugs Future 2005; 30: 877-85.
-
(2005)
Drugs Future
, vol.30
, pp. 877-885
-
-
Sorbera, L.A.1
Bozza, J.2
Castaner, J.3
-
18
-
-
73949100783
-
From old to new anticoagulants: The role of the biologist
-
(Paris)
-
Samama M, Depasse F. From old to new anticoagulants: The role of the biologist. Ann Biol Clin (Paris) 2009; 67(5): 525-34.
-
(2009)
Ann Biol Clin
, vol.67
, Issue.5
, pp. 525-534
-
-
Samama, M.1
Depasse, F.2
-
19
-
-
77953168824
-
Dabigatran etexilate - a novel, reversible, oral direct thrombin inhibitor: Interpretation of coagulation assays and reversal of anticoagulant activity
-
Van Ryn J, Stangier J, Haertter S, Liesenfeld KH, Wienen W, Feuring M, et al. Dabigatran etexilate - a novel, reversible, oral direct thrombin inhibitor: Interpretation of coagulation assays and reversal of anticoagulant activity. Thromb Haemost 2010; 103(6): 1116-27.
-
(2010)
Thromb Haemost
, vol.103
, Issue.6
, pp. 1116-1127
-
-
van Ryn, J.1
Stangier, J.2
Haertter, S.3
Liesenfeld, K.H.4
Wienen, W.5
Feuring, M.6
-
20
-
-
70349306707
-
RELY Dabigatran versus warfarin in patients with atrial fibrillation steering committee and investigators
-
Connolly SJ, Ezekowitz MD, Yusuf S, Eikelboom J, Oldgren J, Parekh A, et al. RELY Dabigatran versus warfarin in patients with atrial fibrillation steering committee and investigators. N Engl J Med 2009; 361(12): 1139-51.
-
(2009)
N Engl J Med
, vol.361
, Issue.12
, pp. 1139-1151
-
-
Connolly, S.J.1
Ezekowitz, M.D.2
Yusuf, S.3
Eikelboom, J.4
Oldgren, J.5
Parekh, A.6
-
21
-
-
85065857997
-
Pharmacokinetics and pharmacodynamics of the new oral anticoagulants dabigatran and rivaroxaban
-
Baines OJP, Grana CE, Botella JA, García VI. Pharmacokinetics and pharmacodynamics of the new oral anticoagulants dabigatran and rivaroxaban. Farm Hosp 2009; 33(3): 125-33.
-
(2009)
Farm Hosp
, vol.33
, Issue.3
, pp. 125-133
-
-
Baines, O.J.P.1
Grana, C.E.2
Botella, J.A.3
García, V.I.4
-
23
-
-
70349306707
-
Dabigatran versus warfarin in patients with atrial fibrillation
-
Connolly SJ, Ezekowitz MD, Yusuf S. Dabigatran versus warfarin in patients with atrial fibrillation. N Engl J Med 2009; 361(12): 1139-51.
-
(2009)
N Engl J Med
, vol.361
, Issue.12
, pp. 1139-1151
-
-
Connolly, S.J.1
Ezekowitz, M.D.2
Yusuf, S.3
-
24
-
-
35449007749
-
Oral dabigatran etexilate vs. subcutaneous enoxaparin for the prevention of venous thromboembolism after total knee replacement: The RE-MODEL randomized trial
-
Eriksson BI, Dahl OE, Rosencher N. Oral dabigatran etexilate vs. subcutaneous enoxaparin for the prevention of venous thromboembolism after total knee replacement: the RE-MODEL randomized trial. J Thromb Haemost 2007; 5(11): 2178-85.
-
(2007)
J Thromb Haemost
, vol.5
, Issue.11
, pp. 2178-2185
-
-
Eriksson, B.I.1
Dahl, O.E.2
Rosencher, N.3
-
25
-
-
57649123692
-
Ginsberg JS, Davidson BL, Comp PC, Francis CS, Friedman RJ, et al. The oral thrombin inhibitor dabigatran etexilate vs the North American enoxaparin regimen for the prevention of venous thromboembolism after knee arthroplasty surgery
-
RE-MOBILIZE Writing Committee
-
RE-MOBILIZE Writing Committee, Ginsberg JS, Davidson BL, Comp PC, Francis CS, Friedman RJ, et al. The oral thrombin inhibitor dabigatran etexilate vs the North American enoxaparin regimen for the prevention of venous thromboembolism after knee arthroplasty surgery. J Arthroplasty 2009; 24(1): 1-9.
-
(2009)
J Arthroplasty
, vol.24
, Issue.1
, pp. 1-9
-
-
-
26
-
-
77956440109
-
Dabigatran etexilate prevents venous thromboembolism after total knee arthroplasty in Japanese patients, with a safety profile comparable to placebo
-
[Epub ahead of print]
-
Fuji T, Fujita S, Ujihira T, Sato T. Dabigatran etexilate prevents venous thromboembolism after total knee arthroplasty in Japanese patients, with a safety profile comparable to placebo. J Arthroplasty 2009 [Epub ahead of print].
-
(2009)
J Arthroplasty
-
-
Fuji, T.1
Fujita, S.2
Ujihira, T.3
Sato, T.4
-
27
-
-
34548575058
-
Dabigatran etexilate versus enoxaparin for prevention of venous thromboembolism after total hip replacement: A randomised, double-blind, non-inferiority trial. Lancet
-
2007; 370 (9604)
-
Eriksson BI, Dahl OE, Rosencher N, Kurth AA, van Dijk CN, Frostick SP, et al. Dabigatran etexilate versus enoxaparin for prevention of venous thromboembolism after total hip replacement: a randomised, double-blind, non-inferiority trial. Lancet 2007; 370(9591): 949-56. Erratum in: Lancet 2007; 370 (9604): 2004.
-
(2007)
Erratum In: Lancet
, vol.370
, Issue.9591
, pp. 949-956
-
-
Eriksson, B.I.1
Dahl, O.E.2
Rosencher, N.3
Kurth, A.A.4
van Dijk, C.N.5
Frostick, S.P.6
-
28
-
-
77957082622
-
Dabigatran etexilate for the prophylaxis of venous thromboembolism after hip or knee replacement: Rationale for dose regimen
-
Dahl OE. Dabigatran etexilate for the prophylaxis of venous thromboembolism after hip or knee replacement: Rationale for dose regimen. Clin Appl Thromb Hemost 2009; 15(Suppl 1): 17S-24S.
-
(2009)
Clin Appl Thromb Hemost
, vol.15
, Issue.SUPPL. 1
-
-
Dahl, O.E.1
-
29
-
-
35348879239
-
Dabigatran with or without concomitant aspirin compared with warfarin alone in patients with nonvalvular atrial fibrillation (PETRO Study)
-
Ezekowitz MD, Reilly PA, Nehmiz G, Simmers TA, Nagarakanti R, Parcham-Azad K, et al. Dabigatran with or without concomitant aspirin compared with warfarin alone in patients with nonvalvular atrial fibrillation (PETRO Study). Am J Cardiol 2007; 100(9):1419-26.
-
(2007)
Am J Cardiol
, vol.100
, Issue.9
, pp. 1419-1426
-
-
Ezekowitz, M.D.1
Reilly, P.A.2
Nehmiz, G.3
Simmers, T.A.4
Nagarakanti, R.5
Parcham-Azad, K.6
-
30
-
-
13244266944
-
Dose escalating safety study of a new oral direct thrombin inhibitor, dabigatran etexilate, in patients undergoing total hip replacement: BISTRO I
-
Eriksson BI, Dahl OE, Ahnfelt L, Kälebo P, Stangier J, Nehmiz G, et al. Dose escalating safety study of a new oral direct thrombin inhibitor, dabigatran etexilate, in patients undergoing total hip replacement: BISTRO I. J Thromb Haemost 2004; 2(9):1573-80.
-
(2004)
J Thromb Haemost
, vol.2
, Issue.9
, pp. 1573-1580
-
-
Eriksson, B.I.1
Dahl, O.E.2
Ahnfelt, L.3
Kälebo, P.4
Stangier, J.5
Nehmiz, G.6
-
31
-
-
75849116330
-
Economic evaluation of dabigatran etexilate for the prevention of venous thromboembolism in patients aged over 75 years or with moderate renal impairment undergoing total knee or hip replacement
-
Wolowacz SE, Roskell NS, Plumb JM, Clemens A, Noack H, Robinson PA, et al. Economic evaluation of dabigatran etexilate for the prevention of venous thromboembolism in patients aged over 75 years or with moderate renal impairment undergoing total knee or hip replacement. Thromb Haemost 2010; 103(2): 360-71.
-
(2010)
Thromb Haemost
, vol.103
, Issue.2
, pp. 360-371
-
-
Wolowacz, S.E.1
Roskell, N.S.2
Plumb, J.M.3
Clemens, A.4
Noack, H.5
Robinson, P.A.6
-
32
-
-
75849116330
-
Economic evaluation of dabigatran etexilate for the preventionof venous thromboembolism in patients aged over 75 years or with moderate renal impairment undergoing total knee or hip replacement
-
Wolowacz SE, Roskell NS, Plumb JM, Clemens A, Noack H, Robinson PA, et al. Economic evaluation of dabigatran etexilate for the preventionof venous thromboembolism in patients aged over 75 years or with moderate renal impairment undergoing total knee or hip replacement. Thromb Haemost 2010; 103(2): 360-71.
-
(2010)
Thromb Haemost
, vol.103
, Issue.2
, pp. 360-371
-
-
Wolowacz, S.E.1
Roskell, N.S.2
Plumb, J.M.3
Clemens, A.4
Noack, H.5
Robinson, P.A.6
-
33
-
-
84886943228
-
Dabigatran etexilate for the prevention of venous thromboembolism in patients undergoing elective hip and knee surgery: A single technology appraisal
-
Holmes M, Carroll C, Papaioannou D. Dabigatran etexilate for the prevention of venous thromboembolism in patients undergoing elective hip and knee surgery: a single technology appraisal. Health Technol Assess 2009; 13 (Suppl 2): 55-62.
-
(2009)
Health Technol Assess
, vol.13
, Issue.SUPPL. 2
, pp. 55-62
-
-
Holmes, M.1
Carroll, C.2
Papaioannou, D.3
-
34
-
-
74049098395
-
Replacing aspirin and warfarin for secondary stroke prevention: Is it worth the costs?
-
[Hankey GJ. Replacing aspirin and warfarin for secondary stroke prevention: Is it worth the costs? Curr Opin Neurol 2010; 23(1): 65-72.
-
(2010)
Curr Opin Neurol
, vol.23
, Issue.1
, pp. 65-72
-
-
Hankey, G.J.1
-
35
-
-
70349306850
-
Can we rely on RELY?
-
Gage BF. Can we rely on RELY? N Engl J Med 2009; 361(12): 1200-2.
-
(2009)
N Engl J Med
, vol.361
, Issue.12
, pp. 1200-1202
-
-
Gage, B.F.1
-
36
-
-
77957090426
-
Oral Antithrombotic inhibitors: Dabigatran etexilate, meeting an unmet need?
-
[Epub ahead of print]
-
Hull RD. Oral Antithrombotic inhibitors: Dabigatran etexilate, meeting an unmet need? Clin Appl Thromb Hemost 2009 [Epub ahead of print].
-
(2009)
Clin Appl Thromb Hemost
-
-
Hull, R.D.1
|