Fluticasone furoate nasal spray is effective and well tolerated for perennial allergic rhinitis in adolescents and adults

American Journal of Rhinology and Allergy

Volumn 24, Issue 6, 2010, Pages 444-450

  Given, John T ^a   Cheema, Amarjit S ^b   Dreykluft, Tilman ^c   Stillerman, Allan ^d   Silvey, MaryJane ^e   Wu, Wei ^e   Snowise, Neil G ^f   Philpot, Edward ^e  

^a Allergy and Respiratory Center   (United States)

^b Alpha Medical Research Inc   (Canada)

^c Klinische Forschung   (Germany)

^d Clinical Research Institute Inc   (United States)

^e GLAXOSMITHKLINE   (United States)

^f GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

FLUTICASONE FUROATE; NOSE SPRAY; PLACEBO;

ADOLESCENT; ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DAILY LIFE ACTIVITY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG WITHDRAWAL; EPISTAXIS; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; PATIENT COMPLIANCE; PERENNIAL RHINITIS; QUALITY OF LIFE; QUESTIONNAIRE; RANDOMIZED CONTROLLED TRIAL; RHINOCONJUNCTIVITIS QUALITY OF LIFE QUESTIONNAIRE; RHINOPHARYNGITIS; SCORING SYSTEM; SYMPTOM; TORAL OCULAR SYMPTOM SCORE; TOTAL NASAL SYMPTOM SCORE; TREATMENT OUTCOME;

ADOLESCENT; ADULT; ANDROSTADIENES; DOUBLE-BLIND METHOD; FEMALE; HUMANS; MALE; MIDDLE AGED; NASAL SPRAYS; QUALITY OF LIFE; RHINITIS, ALLERGIC, PERENNIAL;

EID: 78649975632     PISSN: 19458924     EISSN: 19458932     Source Type: Journal    
DOI: 10.2500/ajra.2010.24.3534     Document Type: Article

References (37)

1. Van Cauwenberge P, Bachert C, Passalacqua G, et al. Consensus statement on the treatment of allergic rhinitis. Allergy 55:116-134, 2000. (Pubitemid 30106016)
2. Dykewicz MS, and Fineman S. Executive summary of Joint Task Force Practice Parameters on Diagnosis and Management of Rhinitis. Ann Allergy Asthma Immunol 81:463-468, 1998.
3. Juniper EF, Guyatt GH, and Dolovich J. Assessment of health-related quality of life in adolescents with allergic rhinoconjunctivitis: Development and testing of a questionnaire for clinical trials. J Allergy Clin Immunol 93:413-423, 1994. (Pubitemid 24081781)
4. Bender BG. Cognitive effects of allergic rhinitis and its treatment. Immunol Allergy Clin North Am 25:301-312, 2005. (Pubitemid 40692711)
5. Pratt EL, and Craig TJ. Assessing outcomes from the sleep disturbance associated with rhinitis. Curr Opin Allergy Clin Immunol 7:249-256, 2007. (Pubitemid 46725767)
6. Léger D, Annesi-Maesano I, Carat F, et al. Allergic rhinitis and its consequences on quality of sleep. Arch Intern Med 166:1744-1748, 2006.
7. Green RJ, Davis G, and Price D. Concerns of patients with allergic rhinitis: The Allergic Rhinitis Care Programme in South Africa. Prim Care Respir J 16:299-303, 2007. (Pubitemid 47607072)
8. Szeinbach SL, Seoane-Vazquez EC, Beyer A, and Williams PB. The impact of allergic rhinitis on work productivity. Prim Care Respir J 16:98-105, 2007. (Pubitemid 46698774)
9. Nathan RA. The burden of allergic rhinitis. Allergy Asthma Proc 28:3-9, 2007.
10. Wang DY, Raza MT, and Gordon BR. Control of nasal obstruction in perennial allergic rhinitis. Curr Opin Allergy Clin Immunol 4:165-170, 2004. (Pubitemid 38685516)
11. Crown WH, Olufade A, Smith MW, and Nathan R. Seasonal versus perennial allergic rhinitis: Drug and medical resource use patterns. Value Health 6:448-456, 2003. (Pubitemid 36929733)
12. Weber RW. Allergic rhinitis. Prim Care 35:1-10, 2008.
13. Task Force on Allergic Disorders - American Academy of Allergy, Asthma, and Immunology. The allergy report.
14. Salib RJ, and Howarth PH. Safety and tolerability profiles of intranasal antihistamines and intranasal corticosteroids in the treatment of allergic rhinitis. Drug Saf 26:863-893, 2003. (Pubitemid 37188249)
15. Allen A, Down G, Newland A, et al. Absolute bioavailability of intranasal fluticasone furoate in healthy subjects. Clin Ther 29:1415-1420, 2007. (Pubitemid 47354209)
16. McCormack PL, and Scott LJ. Fluticasone furoate: Intranasal use in allergic rhinitis. Drugs 67:1905-1915, 2007.
17. Fokkens WJ, Jogi R, Reinartz S, et al. Once daily fluticasone furoate nasal spray is effective in seasonal allergic rhinitis caused by grass pollen. Allergy 62:1078-1084, 2007.
18. Martin BG, Ratner PH, Hampel FC, et al. Optimal dose selection of fluticasone furoate nasal spray for the treatment of seasonal allergic rhinitis in adults and adolescents. Allergy Asthma Proc 28:216-225, 2007.
19. Kaiser HB, Naclerio RM, Given J, et al. Fluticasone furoate nasal spray: A single treatment option for the symptoms of seasonal allergic rhinitis. J Allergy Clin Immunol 119:1430-1437, 2007. (Pubitemid 46855849)
20. Jacobs R, Martin B, Hampel F, et al. Effectiveness of fluticasone furoate 110 mcg once daily in the treatment of nasal and ocular symptoms of seasonal allergic rhinitis in adults and adolescents sensitized to mountain cedar pollen. Curr Med Res Opin 25:1393-1401, 2009. (Epub ahead of print.)
21. Scadding GK, and Keith PK. Fluticasone furoate nasal spray consistently and significantly improves both the nasal and ocular symptoms of seasonal allergic rhinitis: A review of the clinical data. Expert Opin Pharmacother 9:2707-2715, 2008.
22. Nathan RA, Berger W, Yang W, et al. Effect of once-daily fluticasone furoate nasal spray on nasal symptoms in adults and adolescents with perennial allergic rhinitis. Ann Allergy Asthma Immunol 100: 497-505, 2008. (Pubitemid 351668788)
23. Vasar M, Houle P-A, Douglass JA, et al. Fluticasone furoate nasal spray: Effective monotherapy for symptoms of perennial allergic rhinitis in adults/adolescents. Allergy Asthma Proc 29:313-321, 2008.
24. Andrews CP, Martin BG, Jacobs RL, et al. Fluticasone furoate nasal spray is more effective than fexofenadine for nighttime symptoms of seasonal allergy. Allergy Asthma Proc 30:128-138, 2009.
25. Meltzer EO, Lee J, Tripathy I, et al. Efficacy and safety of once-daily fluticasone furoate nasal spray in children with seasonal allergic rhinitis treated for 2 weeks. Pediatr Allergy Immunol 20:279-286, 2009.
26. Rosenblut A, Bardin PG, Muller B, et al. Long-term safety of fluticasone furoate nasal spray in adults and adolescents with perennial allergic rhinitis. Allergy 1071-1077, 2007. (Pubitemid 47220982)
27. Juniper EF, Thompson AK, Ferrie PJ, and Roberts JN. Validation of the standardised version of the Rhinoconjunctivitis Quality of Life Questionnaire. J Allergy Clin Immunol 104:364-369, 1999. (Pubitemid 29420434)
28. Juniper EF, Guyatt GH, Griffith LE, and Ferrie PJ. Interpretation of rhinoconjunctivitis quality of life data. J Allergy Clin Immunol 98: 843-845, 1996. (Pubitemid 26357253)
29. Ciprandi G, Klersy C, Cirillo I, and Marseglia GL. Quality of life in allergic rhinitis: relationship with clinical, immunological, and functional aspects. Clin Exp Allergy 37:1528-1535, 2007. (Pubitemid 47460236)
30. Wilson A. Airflow obstruction and peak nasal inspiratory flow (PNIF). November 2003. Available online at www.clementclarke. com; last accessed October 30, 2009.
31. Wilson A, Dempsey OJ, and Sims EJ. Evaluation of treatment response in patients with seasonal allergic rhinitis using domiciliary nasal peak inspiratory flow. Clin Exp Allergy 30:833-838, 2000. (Pubitemid 30341285)
32. Baroody FM, Foster KA, Markaryan A, et al. Nasal ocular reflexes and eye symptoms in patients with allergic rhinitis. Ann Allergy Asthma Immunol 100:194-199, 2008. (Pubitemid 351397996)
33. Keith PK, and Scadding GK. Are intranasal corticosteroids all equally consistent in managing ocular symptoms of seasonal allergic rhinitis? Curr Med Res Opin 25:2021-2041, 2009.
34. Weiner JM, Abramson MJ, and Puy RM. Intranasal corticosteroids versus oral H1 receptor antagonists in allergic rhinitis: Systematic review of randomised controlled trials. BMJ 317:1624-1629, 1998.
35. Bernstein DI, Levy AL, Hampel FC, et al. Treatment with intranasal fluticasone propionate significantly improves ocular symptoms in patients with seasonal allergic rhinitis. Clin Exp Allergy. 34:952-957, 2004. (Pubitemid 38824075)
36. DeWester J, Philpot EE, Westlund RE, et al. The efficacy of intranasal fluticasone propionate in the relief of ocular symptoms associated with seasonal allergic rhinitis. Allergy Asthma Proc 24:331-337, 2003. (Pubitemid 37414434)
37. Baroody FM, Shenag D, DeTineo M, et al. Fluticasone furoate nasal spray reduces the nasal-ocular reflex: A mechanism for the efficacy of topical steroids in controlling allergic eye symptoms. J Allergy Clin Immunol 123:1342-1348, 2009.