Immune response to the West Nile virus in aged non- human primates

PLoS ONE

Volumn 5, Issue 12, 2010, Pages

  Wertheimer, Anne M ^a   Uhrlaub, Jennifer L ^a,b   Hirsch, Alec ^c   Medigeshi, Guruprasad ^c   Sprague, Jerald ^c   Legasse, Alfred ^d   Wilk, Jennifer ^d   Wiley, Clayton A ^e   Didier, Peter ^f   Tesh, Robert B ^g   Murray, Kristy O ^h   Axthelm, Michael K ^d   Wong, Scott W ^c,d   Nikolich Žugich, Janko ^a,b,d  

^a UNIVERSITY OF ARIZONA   (United States)

^b UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

^c OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^d OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^e UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^f TULANE NATIONAL PRIMATE RESEARCH CENTER   (United States)

^g UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

^h UNIVERSITY OF TEXAS SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIGEN; CD8 ANTIGEN; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; VIRUS RNA;

ADAPTIVE IMMUNITY; AGE; AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; ARTICLE; B LYMPHOCYTE; CONTROLLED STUDY; FEMALE; FLAVIVIRUS INFECTION; IMMUNE RESPONSE; INNATE IMMUNITY; LYMPHOCYTE PROLIFERATION; MALE; NONHUMAN; POLYMERASE CHAIN REACTION; QUANTITATIVE ANALYSIS; RHESUS MONKEY; T CELL DEPLETION; T LYMPHOCYTE; VIREMIA; VIRUS GENOME; VIRUS LOAD; VIRUS SHEDDING; WEST NILE FLAVIVIRUS; AGING; ANIMAL; DISEASE MODEL; IMMUNE SYSTEM; IMMUNOLOGY; LEUKOCYTE; MACACA; MACACA FASCICULARIS; METABOLISM; MOSQUITO; OWL; PRIMATE; SALIVARY GLAND; VIROLOGY; WEST NILE FEVER;

ANIMALIA; MACACA; MACACA MULATTA; PRIMATES; WEST NILE VIRUS;

AGING; ANIMALS; CULICIDAE; DISEASE MODELS, ANIMAL; FEMALE; GENOME, VIRAL; IMMUNE SYSTEM; LEUKOCYTES; MACACA; MACACA FASCICULARIS; MALE; PRIMATES; SALIVARY GLANDS; STRIGIFORMES; WEST NILE FEVER; WEST NILE VIRUS;

EID: 78649943671     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0015514     Document Type: Article

References (27)

1. Chowers MY, Lang R, Nassar F, Ben-David D, Giladi M, et al. (2001) Clinical characteristics of the West Nile fever outbreak, Israel, 2000. Emerg Infect Dis 7: 675-678.
2. Mostashari F, Bunning ML, Kitsutani PT, Singer DA, Nash D, et al. (2001) Epidemic West Nile encephalitis, New York, 1999: results of a household-based seroepidemiological survey. Lancet 358: 261-264.
3. O'Leary DR, Marfin AA, Montgomery SP, Kipp AM, Lehman JA, et al. (2004) The epidemic of West Nile virus in the United States, 2002. Vector Borne Zoonotic Dis 4: 61-70.
4. Diamond MS, Pierson TC, Fremont DH (2008) The structural immunology of antibody protection against West Nile virus. Immunol Rev 225: 212-225.
5. Diamond MS (2009) Progress on the development of therapeutics against West Nile virus. Antiviral Res 83: 214-227.
6. Murray KO, Baraniuk S, Resnick M, Arafat R, Kilborn C, et al. (2008) Clinical investigation of hospitalized human cases of West Nile virus infection in Houston, Texas, 2002-2004. Vector Borne Zoonotic Dis 8: 167-174.
7. Throsby M, Ter Meulen J, Geuijen C, Goudsmit J, de Kruif J (2007) Mapping and analysis of West Nile virus-specific monoclonal antibodies: prospects for vaccine development. Expert Rev Vaccines 6: 183-191.
8. Tesh RB, Siirin M, Guzman H, Travassos da Rosa AP, Wu X, et al. (2005) PersistentWest Nile virus infection in the golden hamster: studies on its mechanism and possible implications for other flavivirus infections. J Infect Dis 192: 287-295.
9. Brien JD, Uhrlaub JL, Hirsch A, Wiley CA, Nikolich-Žugich J (2009) Key role of T cell defects in age-related vulnerability to West Nile virus. J Exp Med 206: 2735-2745.
10. Hein WR, Griebel PJ (2003) A road less travelled: large animal models in immunological research. Nat Rev Immunol 3: 79-84.
11. Ratterree MS, Gutierrez RA, Travassos da Rosa AP, Dille BJ, Beasley DW, et al. (2004) Experimental infection of rhesus macaques with West Nile virus: level and duration of viremia and kinetics of the antibody response after infection. J Infect Dis 189: 669-676.
12. Wolf RF, Papin JF, Hines-Boykin R, Chavez-Suarez M, White GL, et al. (2006) Baboon model for West Nile virus infection and vaccine evaluation. Virology 355: 44-51.
13. Ratterree MS, da Rosa AP, Bohm RP, Jr., Cogswell FB, Phillippi KM, et al. (2003) West Nile virus infection in nonhuman primate breeding colony, concurrent with human epidemic, southern Louisiana. Emerg Infect Dis 9: 1388-1394.
14. Pogodina VV, Frolova MP, Malenko GV, Fokina GI, Koreshkova GV, et al. (1983) Study on West Nile virus persistence in monkeys. Arch Virol 75: 71-86.
15. Armah HB, Wang G, Omalu BI, Tesh RB, Gyure KA, et al. (2007) Systemic distribution of West Nile virus infection: postmortem immunohistochemical study of six cases. Brain Pathol 17: 354-362.
16. Roth GS, Mattison JA, Ottinger MA, Chachich ME, Lane MA, et al. (2004) Aging in rhesus monkeys: relevance to human health interventions. Science 305: 1423-1426.
17. Schneider BS, Higgs S (2008) The enhancement of arbovirus transmission and disease by mosquito saliva is associated with modulation of the host immune response. Trans R Soc Trop Med Hyg 102: 400-408.
18. Beaty BJ, Calisher CH, RE S, eds (1989) Diagnostic procedures for viral, rickettsial and chlamydial infections. 6 ed. WashingtonDC: American Public Heath Association. pp 797-856.
19. Li F, Yarilin DA, Valiando J, Ronco A, Weksler ME, et al. (2002) Tumor antigen drives a persistent oligoclonal expansion of CD8+ T cells in aged mice. Eur J Immunol 32: 1650-1658.
20. Sprent J, Miller JF, Mitchell GF (1971) Antigen-induced selective recruitment of circulating lymphocytes. Cell Immunol 2: 171-181.
21. Petersen LR, Roehrig JT, Hughes JM (2002) West Nile virus encephalitis. N Engl J Med 347: 1225-1226.
22. Murray K, Walker C, Herrington E, Lewis JA, McCormick J, et al. (2010) Persistent infection with West Nile virus years after initial infection. J Infect Dis 201: 2-4.
23. Cicin-Sain L, Messaoudi I, Park B, Currier N, Planer S, et al. (2007) Dramatic increase in naive T cell turnover is linked to loss of naive T cells from old primates. Proc Natl Acad Sci U S A 104: 19960-19965.
24. Pitcher CJ, Hagen SI, Walker JM, Lum R, Mitchell BL, et al. (2002) Development and homeostasis of T cell memory in rhesus macaque. J Immunol 168: 29-43.
25. Cicin-Sain L, Smyk-Pearson S, Currier N, Byrd L, Koudelka C, et al. Loss of naive T cells and repertoire constriction predict poor response to vaccination in old primates. J Immunol 184: 6739-6745.
26. Briese T, Glass WG, Lipkin WI (2000) Detection of West Nile virus sequences in cerebrospinal fluid. Lancet 355: 1614-1615.
27. Malan AK, Stipanovich PJ, Martins TB, Hill HR, Litwin CM (2003) Detection of IgG and IgM to West Nile virus. Development of an immunofluorescence assay. Am J Clin Pathol 119: 508-515.