Molecular profiling of ADAM12 gene in breast cancers

Romanian Journal of Morphology and Embryology

Volumn 51, Issue 4, 2010, Pages 669-676

  Nariţa, Diana ^a   Anghel, A ^a   Seclaman, E ^a   Ilina, R ^a   Cireap, Natalia ^a   Ursoniu, S ^a  

^a VICTOR BABES UNIVERSITY OF MEDICINE AND PHARMACY   (Romania)

Author keywords

ADAM12; Breast cancers; Gene expression; Laser capture microdissection

Indexed keywords

ADAM 12 PROTEIN; ADAM PROTEIN; MEMBRANE PROTEIN; TUMOR MARKER;

ADULT; AGED; ALTERNATIVE RNA SPLICING; ARTICLE; BREAST; BREAST TUMOR; FEMALE; GENE EXPRESSION PROFILING; GENETICS; HUMAN; METABOLISM; MIDDLE AGED; PATHOLOGY; UPREGULATION;

ADAM PROTEINS; ADULT; AGED; ALTERNATIVE SPLICING; BREAST; BREAST NEOPLASMS; FEMALE; GENE EXPRESSION PROFILING; HUMANS; MEMBRANE PROTEINS; MIDDLE AGED; TUMOR MARKERS, BIOLOGICAL; UP-REGULATION;

EID: 78649942371     PISSN: 12200522     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (39)

1. BLOBEL CP, ADAMs: key components in EGFR signalling and development, Nat Rev Mol Cell Biol, 2005, 6(1):32-43.
2. ARRIBAS J, BECH-SERRA JJ, SANTIAGO-JOSEFAT B, ADAMs, cell migration and cancer, Cancer Metastasis Rev, 2006, 25(1):57-68.
3. IBA K, ALBRECHTSEN R, GILPIN B, FRÖHLICH C, LOECHEL F, ZOLKIEWSKA A, ISHIGURO K, KOJIMA T, LIU W, LANGFORD JK, SANDERSON RD, BRAKEBUSCH C, FÄSSLER R, WEWER UM, The cysteine-rich domain of human ADAM 12 supports cell adhesion through syndecans and triggers signaling events that lead to β1 integrin-dependent cell spreading, J Cell Biol, 2000, 149(5):1143-1156.
4. OHTSU H, DEMPSEY PJ, EGUCHI S, ADAMs as mediators of EGF receptor transactivation by G protein-coupled receptors, Am J Physiol Cell Physiol, 2006, 291(1):C1-C10.
5. MOCHIZUKI A, OKADA Y, ADAMs in cancer cell proliferation and progression, Cancer Sci, 2007, 98(5):621-628.
6. MURPHY G, The ADAMs: signalling scissors in the tumour microenvironment, Nat Rev Cancer, 2008, 8(12):929-941.
7. EDWARDS DR, HANDSLEY MM, PENNINGTON CJ, The ADAM metalloproteinases, Mol Aspects Med, 2008, 29(5):258-289.
8. DUFFY MJ, MCKIERNAN E, O'DONOVAN N, MCGOWAN PM, Role of ADAMs in cancer formation and progression, Clin Cancer Res, 2009, 15(4):1140-1144.
9. JACOBSEN J, WEWER UM, Targeting ADAM12 in human disease: head, body or tail?, Curr Pharm Des, 2009, 15(20):2300-2310.
10. KVEIBORG M, ALBRECHTSEN R, COUCHMAN JR, WEWER UM, Cellular roles of ADAM12 in health and disease, Int J Biochem Cell Biol, 2008, 40(9):1685-1702.
11. WEWER UM, MÖRGELIN M, HOLCK P, JACOBSEN J, LYDOLPH MC, JOHNSEN AH, KVEIBORG M, ALBRECHTSEN R, ADAM12 is a four-leafed clover: the excised prodomain remains bound to the mature enzyme, J Biol Chem, 2006, 281(14):9418-9422.
12. FRÖHLICH C, ALBRECHTSEN R, DYRSKJØT L, RUDKJAER L, ØRNTOFT TF, WEWER UM, Molecular profiling of ADAM12 in human bladder cancer, Clin Cancer Res, 2006, 12(24):7359-7368.
13. KVEIBORG M, FRÖHLICH C, ALBRECHTSEN R, TISCHLER V, DIETRICH N, HOLCK P, KRONQVIST P, RANK F, MERCURIO AM, WEWER UM, A role for ADAM12 in breast tumor progression and stromal cell apoptosis, Cancer Res, 2005, 65(11):4754-4761.
14. PEDUTO L, REUTER VE, SCHARA-FUJISAWA A, SHAFFER DR, SCHER HI, BLOBEL CP, ADAM12 is highly expressed in carcinoma-associated stroma and is required for mouse prostate tumor progression, Oncogene, 2006, 25(39):5462-5466.
15. SØRENSEN HP, VIVÈS RR, MANETOPOULOS C, ALBRECHTSEN R, LYDOLPH MC, JACOBSEN J, COUCHMAN JR, WEWER UM, Heparan sulfate regulates ADAM12 through a molecular switch mechanism, J Biol Chem, 2008, 283(46):31920-31932.
16. O'SHEA C, MCKIE N, BUGGY Y, DUGGAN C, HILL AD, MCDERMOTT E, O'HIGGINS N, DUFFY MJ, Expression of ADAM-9 mRNA and protein in human breast cancer, Int J Cancer, 2003, 105(6):754-761.
17. LENDECKEL U, KOHL J, ARNDT M, CARL-MCGRATH S, DONAT H, RÖCKEN C, Increased expression of ADAM family members in human breast cancer and breast cancer cell lines, J Cancer Res Clin Oncol, 2005, 131(1):41-48.
18. KUEFER R, DAY KC, KLEER CG, SABEL MS, HOFER MD, VARAMBALLY S, ZORN CS, CHINNAIYAN AM, RUBIN MA, DAY ML, ADAM15 disintegrin is associated with aggressive prostate and breast cancer diseases, Neoplasia, 2006, 8(4):319-329.
19. SJÖBLOM T, JONES S, WOOD LD, PARSONS DW, LIN J, BARBER TD, MANDELKER D, LEARY RJ, PTAK J, SILLIMAN N, SZABO S, BUCKHAULTS P, FARRELL C, MEEH P, MARKOWITZ SD, WILLIS J, DAWSON D, WILLSON JK, GAZDAR AF, HARTIGAN J, WU L, LIU C, PARMIGIANI G, PARK BH, BACHMAN KE, PAPADOPOULOS N, VOGELSTEIN B, KINZLER KW, VELCULESCU VE, The consensus coding sequences of human breast and colorectal cancers, Science, 2006, 314(5797):268-274.
20. EMMERT-BUCK MR, BONNER RF, SMITH PD, CHUAQUI RF, ZHUANG Z, GOLDSTEIN SR, WEISS RA, LIOTTA LA, Laser capture microdissection, Science, 1996, 274(5289):998-1001.
21. FEND F, RAFFELD M, Laser capture microdissection in pathology, J Clin Pathol, 2000, 53(9):666-672.
22. OKUDUCU AF, JANZEN V, HAHNE JC, WERNERT N, Influence of histochemical stains on quantitative gene expression analysis after laser-assisted microdissection, Int J Mol Med, 2003, 11(4):449-453.
23. ESPINA V, WULFKUHLE JD, CALVERT VS, VANMETER A, ZHOU W, COUKOS G, GEHO DH, PETRICOIN III EF, LIOTTA LA, Laser-capture microdissection, Nature Protocols, 2006, 2(1):586-602.
24. DE KOK JB, ROELOFS RW, GIESENDORF BA, PENNINGS JL, WAAS ET, FEUTH T, SWINKELS DW, SPAN PN, Normalization of gene expression measurements in tumor tissues: comparison of 13 endogeneous control genes, Lab Invest, 2005, 85(1):154-159.
25. LIVAK KJ, SCHMITTGEN TD, Analysis of relative gene expression data using real-time quantitative PCR and the 2-ΔΔCT method, Methods San Diego (Calif), 2001, 25(4):402-408.
26. MCGOWAN PM, MCKIERNAN E, BOLSTER F, RYAN BM, HILL ADK, MCDERMOTT EW, EVOY D, O'HIGGINS N, CROWN J, DUFFY MJ, ADAM-17 predicts adverse outcome in patients with breast cancer, Ann Oncol, 2008, 19(6):1075-1081.
27. SHI Z, XU W, LOECHEL F, WEWER UM, MURPHY LJ, ADAM12, a disintegrin and metalloprotease, interacts with insulinlike growth factor-binding protein-3, J Biol Chem, 2000, 275(24):18574-18580.
28. LAIGAARD J, SØRENSEN T, FRÖHLICH C, PEDERSEN BN, CHRISTIANSEN M, SCHIØTT K, ULDBJERG N, ALBRECHTSEN R, CLAUSEN HV, OTTESEN B, WEWER UM, ADAM12: a novel first-trimester maternal serum marker for Down syndrome, Prenat Diagn, 2003, 23(13):1086-1091.
29. ROY R, WEWER MU, ZURAKOWSKI D, PORIES SE, MOSES MA, ADAM 12 cleaves extracellular matrix proteins and correlates with cancer status and stage, J Biol Chem, 2004, 279(49):51323-51330.
30. PORIES SE, ZURAKOWSKI D, ROY R, LAMB CC, RAZA S, EXARHOPOULOS A, SCHEIB RG, SCHUMER S, LENAHAN C, BORGES V, LOUIS GW, ANAND A, ISAKOVICH N, HIRSHFIELDBARTEK J, WEWER U, LOTZ MM, MOSES MA, Urinary metalloproteinases: noninvasive biomarkers for breast cancer risk assessment, Cancer Epidemiol Biomarkers Prev, 2008, 17(5):1034-1042.
31. MICHEL C, DESDOUETS C, SACRE-SALEM B, GAUTIER JC, ROBERTS R, BOITIER E, Liver gene expression profiles of rats treated with clofibric acid: comparison of whole liver and laser capture microdissected liver, Am J Pathol, 2003, 163(6):2191-2199.
32. ERICKSON HS, ALBERT PS, GILLESPIE JW, WALLIS BS, RODRIGUEZ-CANALES J, LINEHAN WM, GONZALES S, VELASCO A, CHUAQUI RF, EMMERT-BUCK MR, Normalization strategies for quantitative RT-PCR in microdissected tissue, Lab Invest, 2007, 87(9):951-962.
33. LE PABIC H, BONNIER D, WEWER UM, COUTAND A, MUSSO O, BAFFET G, CLÉMENT B, THÉRET N, ADAM12 in human liver cancers: TGF-β-regulated expression in stellate cells is associated with matrix remodeling, Hepatology, 2003, 37(5):1056-1066.
34. KODAMA T, IKEDA E, OKADA A, OHTSUKA T, SHIMODA M, SHIOMI T, YOSHIDA K, NAKADA M, OHUCHI E, OKADA Y, ADAM12 is selectively overexpressed in human glioblastomas and is associated with glioblastoma cell proliferation and shedding of heparin-binding epidermal growth factor, Am J Pathol, 2004, 165(5):1743-1753.
35. TURASHVILI G, BOUCHAL J, BAUMFORTH K, WEI W, DZIECHCIARKOVA M, EHRMANN J, KLEIN J, FRIDMAN E, SKARDA J, SROVNAL J, HAJDUCH M, MURRAY P, KOLAR Z, Novel markers for differentiation of lobular and ductal invasive breast carcinomas by laser microdissection and microarray analysis, BMC Cancer, 2007, 7:55.
36. DYCZYNSKA E, SYTA E, SUN D, ZOLKIEWSKA A, Breast cancer-associated mutations in metalloprotease disintegrin ADAM12 interfere with the intracellular trafficking and processing of the protein, Int J Cancer, 2008, 122(11):2634-2640.
37. ATFI A, DUMONT E, COLLAND F, BONNIER D, L'HELGOUALC'H A, PRUNIER C, FERRAND N, CLÉMENT B, WEWER UM, THÉRET N, The disintegrin and metalloproteinase ADAM12 contributes to TGF-β signaling through interaction with the type II receptor, J Cell Biol, 2007, 178(2):201-208.
38. BIERIE B, MOSES HL, Tumour microenvironment: TGFβ: the molecular Jekyll and Hyde of cancer, Nat Rev Cancer, 2006, 6(7):506-520.
39. NIIMI H, PARDALI K, VANLANDEWIJCK M, HELDIN CH, MOUSTAKAS A, Notch signaling is necessary for epithelial growth arrest by TGF-β, J Cell Biol, 2007, 176(5):695-707.