New biodegradable hydrogels based on inulin and α,β- polyaspartylhydrazide designed for colonic drug delivery: In vitro release of glutathione and oxytocin

Journal of Biomaterials Science, Polymer Edition

Volumn 22, Issue 1-3, 2011, Pages 313-328

  Mandracchia, Delia ^a   Denora, Nunzio ^a   Franco, Massimo ^a   Pitarresi, Giovanna ^b   Giammona, Gaetano ^b,c   Trapani, Giuseppe ^a  

^a UNIVERSITY OF BARI   (Italy)

^b UNIVERSITY OF PALERMO   (Italy)

^c CNR   (Italy)

Author keywords

biocompatible matrix; colon delivery; hybrid hydrogels; Inulin; peptide release; ; polyaspartylhydrazide

Indexed keywords

BIOCOMPATIBILITY; CONTROLLED DRUG DELIVERY; COUPLING AGENTS; CROSSLINKING; HYDROGELS; PEPTIDES; POLYSACCHARIDES; SWELLING;

BIODEGRADABLE HYDROGELS; CARBODIIMIDE HYDROCHLORIDES; COLON DELIVERY; COLONIC DRUG DELIVERY; HYBRID HYDROGELS; INFLAMMATORY BOWEL DISEASE; INULIN; PEPTIDE RELEASE;

TARGETED DRUG DELIVERY;

1 (3 DIMETHYLAMINOPROPYL) 3 ETHYLCARBODIIMIDE; ALPHA,BETA POLYASPARTYLHYDRAZIDE; GLUTATHIONE; HYDRAZIDE DERIVATIVE; INULIN; INULINASE; N HYDROXYSULFOSUCCINIMIDE; OXYTOCIN; SUCCINIMIDE DERIVATIVE; UNCLASSIFIED DRUG; CYANAMIDE; DIMETHYLAMINE; HYDROGEL; MUCIN; N-ETHYL-N'-(3-(DIMETHYLAMINO)-PROPYL)CARBODIIMIDE; N-HYDROXYSULFOSUCCINIMIDE; PEPTIDE; POLY(ASPARTYLHYDRAZIDE);

ARTICLE; BIOCOMPATIBILITY; BIODEGRADABILITY; CELL ASSAY; CELL STRAIN CACO 2; CELL VIABILITY; COLITIS; CONTROLLED STUDY; CROSS LINKING; DERIVATIZATION; DRUG DELIVERY SYSTEM; DRUG DESIGN; DRUG RELEASE; ENTERITIS; GEL PERMEATION CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; HYDROGEL; HYDROLYSIS; IN VITRO STUDY; INFRARED SPECTROSCOPY; INTESTINE FLUID; PRIORITY JOURNAL; REACTION TIME; ANALOGS AND DERIVATIVES; CACO 2 CELL LINE; CELL SURVIVAL; CHEMICAL STRUCTURE; CHEMISTRY; COLON; EVALUATION STUDY; INFLAMMATORY BOWEL DISEASES; MATERIALS TESTING; PH; TIME FACTOR;

CACO-2 CELLS; CARBODIIMIDES; CELL SURVIVAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COLON; DIMETHYLAMINES; DRUG DELIVERY SYSTEMS; GLUTATHIONE; HUMANS; HYDROGELS; HYDROGEN-ION CONCENTRATION; HYDROLYSIS; INFLAMMATORY BOWEL DISEASES; INULIN; MATERIALS TESTING; MOLECULAR STRUCTURE; MUCINS; OXYTOCIN; PEPTIDES; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; SUCCINIMIDES; TIME FACTORS;

EID: 78649925035     PISSN: 09205063     EISSN: 15685624     Source Type: Journal    
DOI: 10.1163/092050609X12609582084086     Document Type: Article

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