Crude aqueous extract of garlic reduces MIC of isoniazid and rifampicin against mycobacterium tuberculosis by broth microdilution method

Journal of Complementary and Integrative Medicine

Volumn 7, Issue 1, 2010, Pages

  Dhamija, Puneet ^a   Sethi, Sunil ^a   Meharwal, Sandeep ^a   Kumar, Shiv ^a   Malhotra, Samir ^a   Sharma, Meera ^a   Pandhi, Promila ^a  

^a POSTGRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH   (India)

Author keywords

Allium sativum; broth microdilution method; mycobacteria

Indexed keywords

CRUDE GARLIC EXTRACT; GARLIC EXTRACT; ISONIAZID; RIFAMPICIN; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL STRAIN; BROTH DILUTION; CONTROLLED STUDY; DRUG SYNTHESIS; MINIMUM INHIBITORY CONCENTRATION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; TUBERCULOSIS;

EID: 78649917254     PISSN: 15533840     EISSN: None     Source Type: Journal    
DOI: 10.2202/1553-3840.1449     Document Type: Article

References (15)

1. Abbruzzese MR, Delaha FC, Garagusi VF. (1987) Absence of antimycobacterial synergism between garlic extract and antituberculosis drugs. Diagn Microbiol Infect Dis; 8(2):79-85.
2. Ankri S, Miron T, Rabinkkov A, Wilchek M, Mirelman D. (1997) Allicin from garlic strongly inhibits cysteine proteases and cytopathic effects on Entamoeba histolytica. Antimicrob Agents Chemother; 40:2286-8.
3. Banfi E, Scialino G. (2003) Development of a microdilution method to evaluate Mycobacterium tuberculosis drug susceptibility. J Antimicrobiol Chemother; 52:796-800.
4. Cavallito C, Bailley JH. (1944) Allicin, the antibacterial principle of Allium sativum. Isolation, physical properties and antibacterial action. J Am Chem soc; 66:1944-52.
5. Coban AY, Birinci A, Fkinci B, Durupinar B. (2004) Drug susceptibility testing of Mycobacterium tuberculosis by the broth microdilution method with 7H9 broth. Mem Inst Oswaldo Cruz; 99(1):111-3. (Pubitemid 38406275)
6. Delaha EC, Garagusi VF. (1985) Inhibition of mycobacteria by garlic extract. Antimicrob Agents Chemother; 27(4):485-6.
7. Friedberg RS, Chang SC, Kotik AN, Nadler M, Neuwirth Z, Thompson NH. (1988) In vitro mechanism of inhibition of bacterial cell growth by allicin. Antimicrob Agents Chemother; 32:1763-68.
8. Fromtling RA, Bulmer GS. (1978) In vitro effect of aqueous extract of garlic (Allium sativum) on growth and viability of Cryptococcus neoformans. Mycologia; 70:397-405.
9. Harris JC, Cottrell SL, Plummer S, Lloyd D. (2001). Antimicrobial properties of Allium sativum (garlic). Appl Microbiol Biotechnol; 57:282-6.
10. rd ed. London Pharmaceutical Press.
11. Ozolin ON, Ureshev TA, Kim LA, Deev AA. (1990) Specific modification of alpha-subunit fo E.coli RNA polymerase by monomeric derivative of fluorescein mercuric acetate. Mol Biol (mosk); 24:1057-66.
12. th edn. New York: Mc Graw Hill Companies Inc., 2001:1275.
13. th edn. New York: Mc Graw Hill Companies Inc., 2001:1278.
14. Rao RR, Rao SS, Natrajan S, Venkatraman PR. (1945) Inhibition of Mycobacterium tuberculosis by garlic extract. Nature; 157:441.
15. San-Blas G, Urbina JA, Marchan E, Sorias F. (1997) Inhibition of Paracoccidioides brasillensis by ajoene is associated with blockade of phosphatidylcholine biosynthesis. Microbiology; 143:1583-86.