Symptoms and reflux in infants: Infant gastroesophageal reflux questionnaire revised (I-GERQ-R)-utility for symptom tracking and diagnosis

Current Gastroenterology Reports

Volumn 12, Issue 6, 2010, Pages 431-436

  Orenstein, Susan R ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Clinical trial; Diagnostic validity; Erosive; Evaluative validity; Gastroesophageal reflux; Histology; I GERQ; I GERQ R; Infant; Morphometric; Nonerosive reflux disease; Questionnaire; Reflux; Symptom Association Probability; Symptom Index; Symptom Sensitivity Index; Symptoms; Validity

Indexed keywords

LANSOPRAZOLE; OMEPRAZOLE; PLACEBO;

CLINICAL TRIAL; DEMOGRAPHY; DIAGNOSTIC VALUE; ESOPHAGUS PH; GASTROESOPHAGEAL REFLUX; HEARTBURN; HUMAN; INFANT; INFANT GASTROESOPHAGEAL REFLUX QUESTIONNAIRE REVISED; MONITORING; NOTE; QUESTIONNAIRE; REFLUX ESOPHAGITIS; SCORING SYSTEM; SCREENING; SENSITIVITY AND SPECIFICITY; SYMPTOM; VALIDATION PROCESS;

CLINICAL TRIALS AS TOPIC; GASTROESOPHAGEAL REFLUX; HUMANS; INFANT; PSYCHOMETRICS; QUESTIONNAIRES; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 78649909132     PISSN: 15228037     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11894-010-0140-1     Document Type: Note

References (23)

1. JJ Barron H Tan J Spalding, et al. 2007 Proton pump inhibitor utilization patterns in infants J Pediatr Gastroenterol Nutr 45 421 427 1:CAS:528:DC%2BD2sXht1aiu7%2FO 10.1097/MPG.0b013e31812e0149 18030207 (Pubitemid 350307159)
2. SR Orenstein E Hassall 2007 Infants and proton pump inhibitors: tribulations, no trials [invited editorial] J Pediatr Gastroenterol Nutr 45 395 398 10.1097/MPG.0b013e31812e011d 18030202 (Pubitemid 350307154)
3. L Kleinman DA Revicki E Flood 2006 Validation issues in questionnaires for diagnosis and monitoring of gastroesophageal reflux disease in children Curr Gastroenterol Rep 8 230 236 10.1007/s11894-006-0080-y 16764789
4. L Kleinman M Rothman R Strauss, et al. 2006 The Infant Gastroesophageal Reflux Questionnaire Revised: development and validation as an evaluative instrument Clin Gastro Hep 4 588 596 10.1016/j.cgh.2006.02.016
5. SR Orenstein JF Cohn TM Shalaby R Kartan 1993 Reliability and validity of an infant gastroesophageal reflux questionnaire Clin Pediatr 32 472 484 1:STN:280:DyaK2c%2FgslGguw%3D%3D 10.1177/000992289303200806
6. SR Orenstein TM Shalaby JF Cohn 1996 Reflux symptoms in 100 normal infants: diagnostic validity of the Infant Gastroesophageal Reflux Questionnaire Clin Pediatr 35 607 614 1:STN:280:DyaK2s7isFKrsg%3D%3D 10.1177/ 000992289603501201
7. V Khoshoo P Dhume 2008 Clinical response to 2 dosing regimens of lansoprazole in infants with gastroesophageal reflux J Pediatr Gastroenterol Nutr 46 352 354 1:CAS:528:DC%2BD1cXjt1Cisrk%3D 10.1097/MPG.0b013e31815667d7 18376260
8. SR Orenstein E Hassall W Furmaga-Jablonska, et al. 2009 Multicenter, double-blind, randomized, placebo-controlled trial assessing efficacy and safety of proton pump inhibitor lansoprazole in infants with symptoms of gastroesophageal reflux disease J Pediatr 154 514 520 1:CAS:528: DC%2BD1MXjslOntrg%3D 10.1016/j.jpeds.2008.09.054 19054529
9. H Winter P Kum-Nji SH Mahomedy, et al. 2010 Efficacy and safety of pantoprazole delayed-release granules for oral suspension in a placebo-controlled treatment-withdrawal study in infants 1-11 months old with symptomatic GERD J Pediatr Gastroenterol Nutr 50 609 618 1:CAS:528: DC%2BC3cXmsFCjsrY%3D 10.1097/MPG.0b013e3181c2bf41 20400912
10. Orenstein SR, Hassall E: Pantoprazole for symptoms of infant GERD: the emperor has no clothes! J Pediatr Gastroenterol Nutr, in press.
11. DJ Moore BS-K Tao DR Lines, et al. 2003 Double-blind placebo-controlled trial of omeprazole in irritable infants with gastroesophageal reflux J Pediatr 143 219 223 1:CAS:528:DC%2BD3sXnt1ams7g%3D 10.1067/S0022-3476(03)00207-5 12970637 (Pubitemid 37082956)
12. S Salvatore B Hauser K Vandemaele, et al. 2005 Gastroesophageal reflux disease in infants: How much is predictable with questionnaires, pH-metry, endoscopy and histology? J Pediatr Gastroenterol Nutr 40 210 215 10.1097/00005176-200502000-00024 15699699 (Pubitemid 40269744)
13. PM Sherman E Hassall U Fagundes-Neto, et al. 2009 A global, evidence-based consensus on the definition of gastroesophageal reflux disease in the pediatric population Am J Gastroenterol 104 1278 1295 10.1038/ajg.2009.129 19352345
14. SC Luthold MK Rochat P Bahler 2010 Disagreement between symptom-reflux association parameters in gastroesophageal reflux disease investigation World J Gastroenterol 16 2401 2406 10.3748/wjg.v16.i19.2401 20480526
15. AP Feranchak SR Orenstein JF Cohn 1994 Behaviors associated with onset of gastroesophageal reflux episodes in infants: prospective study using split-screen video and pH probe Clin Pediatr 33 654 662 1:STN:280: DyaK2M7mtlamtA%3D%3D 10.1177/000992289403301104
16. DD Black RC Haggitt SR Orenstein PF Whitington 1990 Esophagitis in infants: morphometric histologic diagnosis and correlation with measures of gastroesophageal reflux Gastroenterology 98 1408 1414 1:STN:280: DyaK3c3kvFKhtQ%3D%3D 2338184
17. MT Sabri SZ Hussain TM Shalaby SR Orenstein 2007 Morphometric histology for infant gastroesophageal reflux disease: evaluation of reliability in 497 esophageal biopsies J Pediatr Gastroenterol Nutr 44 27 34 10.1097/01.mpg. 0000243424.01593.11 17204949 (Pubitemid 46071788)
18. AM Ravelli V Villanacci N Ruzzenenti, et al. 2006 Dilated Intercellular spaces: a major morphological feature of esophagitis J Pediatr Gastroenterol Nutr 42 510 515 10.1097/01.mpg.0000215312.78664.b9 16707972 (Pubitemid 43804728)
19. RC Orlando 2006 Current understanding of the mechanisms of gastro-oesophageal reflux Drugs 66 Suppl 1 1 5 1:CAS:528:DC%2BD28XltlKjtLY%3D 10.2165/00003495-200666001-00002 16869342
20. SR Orenstein TM Shalaby EA Frankel SF Kelsey 2004 Cimetidine, cisapride, both, or neither for infantile esophagitis: symptomatic response to 6-months randomized, double-blind, placebo-controlled therapy in 100 babies Gastroenterology 126 Suppl 2 239
21. TM Shalaby SR Orenstein 2003 Efficacy of telephone teaching of conservative therapy for infants with symptomatic gastroesophageal reflux referred by pediatricians to pediatric gastroenterologists J Pediatr 142 57 61 10.1067/mpd.2003.mpd0331 12520256 (Pubitemid 36106390)
22. SR Orenstein TM Shalaby SF Kelsey E Frankel 2006 Natural history of infant reflux esophagitis: symptoms and morphometric histology during one year without pharmacotherapy Am J Gastroenterol 101 628 640 10.1111/j.1572-0241.2006. 00442.x 16542296 (Pubitemid 43340942)
23. SR Orenstein 2008 Crying in infant GERD: acid or volume? Heartburn or dyspepsia? Cur Gastroenterol Rep 10 433 436 10.1007/s11894-008-0080-1