Anticancer effects of the nitric oxide-modified saquinavir derivative saquinavir-NO against multidrug-resistant cancer cells

Neoplasia

Volumn 12, Issue 12, 2010, Pages 1023-1030

  Rothweiler, Florian ^a   Michaelis, Martin ^a   Brauer, Peter ^a   Otte, Jürgen ^a   Weber, Kristoffer ^b   Fehse, Boris ^b   Doerr, Hans Wilhelm ^a   Wiese, Michael ^c   Kreuter, Jörg ^d   Al Abed, Yousef ^e   Nicoletti, Ferdinando ^f   Cinatl Jr , Jindrich ^a  

^a UNIVERSITY HOSPITAL FRANKFURT   (Germany)

^b UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^c UNIVERSITY OF BONN   (Germany)

^d GOETHE UNIVERSITY   (Germany)

^e North Shore Long Island Jewish Health System ^*  (United States)

^f UNIVERSITY OF CATANIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

6 CARBOXYFLUORESCEIN; BREAST CANCER RESISTANCE PROTEIN; DACTINOMYCIN; GLUTATHIONE; MITOXANTRONE; MULTIDRUG RESISTANCE PROTEIN 1; N ETHYLMALEIMIDE; NITRIC OXIDE; PACLITAXEL; PROTEIN P53; RHODAMINE 123; SAQUINAVIR; VERAPAMIL; VERLUKAST; VINCRISTINE;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; C57BL 6 MOUSE; CANCER CELL; CANCER CELL CULTURE; CANCER COMBINATION CHEMOTHERAPY; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; GLIOMA CELL; MOUSE; MULTIDRUG RESISTANCE; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SENSITIZATION; UPREGULATION;

EID: 78649896393     PISSN: 15228002     EISSN: 14765586     Source Type: Journal    
DOI: 10.1593/neo.10856     Document Type: Article

References (4)

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2. Beyer WR, Westphal M, Ostertag W, and von Laer D (2002). Oncoretrovirus and lentivirus vectors pseudotyped with lymphocytic choriomeningitis virus glyco- protein: generation, concentration, and broad host range. J Virol 76, 1488-1495.
3. Dull T, Zufferey R, Kelly M, Mandel RJ, Nguyen M, Trono D, and Naldini L (1998). A third-generation lentivirus vector with a conditional packaging system. J Virol 72, 8463-8471.
4. Michaelis M, Suhan T, Cinatl J, Driever PH, and Cinatl J, Jr (2004). Valproic acid and interferon-alpha synergistically inhibit neuroblastoma cell growth in vitro and in vivo. Int J Oncol 25, 1795-1799.