-
1
-
-
0026483786
-
ZAP-70: A 70 kd protein-tyrosine kinase that associates with the TCR zeta chain
-
A.C. Chan, M. Iwashima, C.W. Turck, and A. Weiss ZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR zeta chain Cell 71 1992 649 662
-
(1992)
Cell
, vol.71
, pp. 649-662
-
-
Chan, A.C.1
Iwashima, M.2
Turck, C.W.3
Weiss, A.4
-
2
-
-
0028321540
-
Molecular cloning of human Syk. A B cell protein-tyrosine kinase associated with the surface immunoglobulin M-B cell receptor complex
-
C.L. Law, S.P. Sidorenko, K.A. Chandran, K.E. Draves, A.C. Chan, and A. Weiss Molecular cloning of human Syk. A B cell protein-tyrosine kinase associated with the surface immunoglobulin M-B cell receptor complex J Biol Chem 269 1994 12310 12319
-
(1994)
J Biol Chem
, vol.269
, pp. 12310-12319
-
-
Law, C.L.1
Sidorenko, S.P.2
Chandran, K.A.3
Draves, K.E.4
Chan, A.C.5
Weiss, A.6
-
3
-
-
0030795305
-
Regulation of T-cell antigen receptor signalling by Syk tyrosine protein kinase
-
S. Latour, M. Fournel, and A. Veillette Regulation of T-cell antigen receptor signalling by Syk tyrosine protein kinase Mol Cell Biol 17 1997 4434 4441
-
(1997)
Mol Cell Biol
, vol.17
, pp. 4434-4441
-
-
Latour, S.1
Fournel, M.2
Veillette, A.3
-
4
-
-
0028216232
-
Differential expression of ZAP-70 and Syk protein tyrosine kinases, and the role of this family of protein tyrosine kinases in TCR signaling
-
A.C. Chan, N.S. van Oers, A. Tran, L. Turka, C.L. Law, and J.C. Ryan Differential expression of ZAP-70 and Syk protein tyrosine kinases, and the role of this family of protein tyrosine kinases in TCR signaling J Immunol 152 1994 4758 4766
-
(1994)
J Immunol
, vol.152
, pp. 4758-4766
-
-
Chan, A.C.1
Van Oers, N.S.2
Tran, A.3
Turka, L.4
Law, C.L.5
Ryan, J.C.6
-
5
-
-
0026752591
-
A tyrosine-phosphorylated 70-kDa protein binds a photoaffinity analogue of ATP and associates with both the zeta chain and CD3 components of the activated T cell antigen receptor
-
R.L. Wange, A.N. Kong, and L.E. Samelson A tyrosine-phosphorylated 70-kDa protein binds a photoaffinity analogue of ATP and associates with both the zeta chain and CD3 components of the activated T cell antigen receptor J Biol Chem 267 1992 11685 11688
-
(1992)
J Biol Chem
, vol.267
, pp. 11685-11688
-
-
Wange, R.L.1
Kong, A.N.2
Samelson, L.E.3
-
6
-
-
0025136809
-
Stimulation via CD3 Ti but not CD2 induces rapid tyrosine phosphorylation of a 68-kDa protein in the human Jurkat T cell line
-
Y.J. Jin, D.R. Kaplan, M. White, G.C. Spagnoli, T.M. Roberts, and E.L. Reinherz Stimulation via CD3 Ti but not CD2 induces rapid tyrosine phosphorylation of a 68-kDa protein in the human Jurkat T cell line J Immunol 144 1990 647 652
-
(1990)
J Immunol
, vol.144
, pp. 647-652
-
-
Jin, Y.J.1
Kaplan, D.R.2
White, M.3
Spagnoli, G.C.4
Roberts, T.M.5
Reinherz, E.L.6
-
7
-
-
0029151944
-
Activating and inhibitory mutations in adjacent tyrosines in the kinase domain of ZAP-70
-
R.L. Wange, R. Guitian, N. Isakov, J.D. Watts, R. Aebersold, and L.E. Samelson Activating and inhibitory mutations in adjacent tyrosines in the kinase domain of ZAP-70 J Biol Chem 270 1995 18730 18733
-
(1995)
J Biol Chem
, vol.270
, pp. 18730-18733
-
-
Wange, R.L.1
Guitian, R.2
Isakov, N.3
Watts, J.D.4
Aebersold, R.5
Samelson, L.E.6
-
8
-
-
0028269436
-
Defective T cell receptor signaling and CD8+ thymic selection in humans lacking zap-70 kinase
-
E. Arpaia, M. Shahar, H. Dadi, A. Cohen, and C.M. Roifman Defective T cell receptor signaling and CD8+ thymic selection in humans lacking zap-70 kinase Cell 76 1994 947 958
-
(1994)
Cell
, vol.76
, pp. 947-958
-
-
Arpaia, E.1
Shahar, M.2
Dadi, H.3
Cohen, A.4
Roifman, C.M.5
-
10
-
-
0024317079
-
Depletion of CD8+ cells in human thymic medulla results in selective immune deficiency
-
C.M. Roifman, D. Hummel, H. Martinez-Valdez, P. Thorner, P.J. Doherty, and S. Pan Depletion of CD8+ cells in human thymic medulla results in selective immune deficiency J Exp Med 170 1989 2177 2182
-
(1989)
J Exp Med
, vol.170
, pp. 2177-2182
-
-
Roifman, C.M.1
Hummel, D.2
Martinez-Valdez, H.3
Thorner, P.4
Doherty, P.J.5
Pan, S.6
-
11
-
-
22344445528
-
New insights on human T cell development by quantitative T cell receptor gene rearrangement studies and gene expression profiling
-
W.A. Dik, K. Pike-Overzet, F. Weerkamp, D. de Ridder, E.F.E. de Haas, and M.R.M. Baert New insights on human T cell development by quantitative T cell receptor gene rearrangement studies and gene expression profiling J Exp Med 201 2007 1715 1723
-
(2007)
J Exp Med
, vol.201
, pp. 1715-1723
-
-
Dik, W.A.1
Pike-Overzet, K.2
Weerkamp, F.3
De Ridder, D.4
De Haas, E.F.E.5
Baert, M.R.M.6
-
12
-
-
32044458418
-
Novel RAG1 Mutation in a Case of Severe Combined Immunodeficiency
-
J. Zhang, L. Quintal, A. Atkinson, B. Williams, E. Grunebaum, and C.M. Roifman Novel RAG1 Mutation in a Case of Severe Combined Immunodeficiency Pediatrics 116 2005 e445 e449
-
(2005)
Pediatrics
, vol.116
-
-
Zhang, J.1
Quintal, L.2
Atkinson, A.3
Williams, B.4
Grunebaum, E.5
Roifman, C.M.6
-
13
-
-
70449732278
-
Reduced central tolerance in Omenn syndrome leads to immature self reactive oligoclonal T cells
-
R. Somech, A.J. Simon, A. Lev, I. Dalal, Z. Spirer, and I. Goldstein Reduced central tolerance in Omenn syndrome leads to immature self reactive oligoclonal T cells J Allergy Clin Immunol 124 2009 793 800
-
(2009)
J Allergy Clin Immunol
, vol.124
, pp. 793-800
-
-
Somech, R.1
Simon, A.J.2
Lev, A.3
Dalal, I.4
Spirer, Z.5
Goldstein, I.6
-
14
-
-
0034720664
-
Assessment of thymic output in adults after haematopoietic stem cell transplantation and prediction of T-cell reconstitution
-
D.C. Douek, R.A. Vescio, M.R. Betts, J.M. Brenchley, B.J. Hill, and L. Zhang Assessment of thymic output in adults after haematopoietic stem cell transplantation and prediction of T-cell reconstitution Lancet 355 2000 1875 1881
-
(2000)
Lancet
, vol.355
, pp. 1875-1881
-
-
Douek, D.C.1
Vescio, R.A.2
Betts, M.R.3
Brenchley, J.M.4
Hill, B.J.5
Zhang, L.6
-
15
-
-
0242285603
-
Effect of CD3δ deficiency on Maturation of α/β and γ/δ T-cell lineages in severe combined immunodeficiency
-
H.K. Dadi, A.J. Simon, and C.M. Roifman Effect of CD3δ deficiency on Maturation of α/β and γ/δ T-cell lineages in severe combined immunodeficiency N Engl J Med 349 2003 1821 1828
-
(2003)
N Engl J Med
, vol.349
, pp. 1821-1828
-
-
Dadi, H.K.1
Simon, A.J.2
Roifman, C.M.3
-
16
-
-
0035162560
-
Disruption of a new forkhead/winged helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse
-
M.E. Brunkow, E.W. Jeffrey, K.A. Hjerrild, B. Paeper, L.B. Clark, and S.A. Yasayko Disruption of a new forkhead/winged helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse Nat Genet 27 2001 68 73
-
(2001)
Nat Genet
, vol.27
, pp. 68-73
-
-
Brunkow, M.E.1
Jeffrey, E.W.2
Hjerrild, K.A.3
Paeper, B.4
Clark, L.B.5
Yasayko, S.A.6
-
18
-
-
33748448717
-
Transforming growth factor beta controls development, homeostasis, and tolerance of T cells by regulatory T cell dependant and independent mechanisms
-
M.O. Li, S. Sanjabi, and R.A. Flavell Transforming growth factor beta controls development, homeostasis, and tolerance of T cells by regulatory T cell dependant and independent mechanisms Immunity 25 2006 455 471
-
(2006)
Immunity
, vol.25
, pp. 455-471
-
-
Li, M.O.1
Sanjabi, S.2
Flavell, R.A.3
-
19
-
-
33748465396
-
Cellular mechanisms of fatal early-onset autoimmunity in mice with the T cell specific targeting of transforming growth factor-beta receptor
-
J.C. Marie, D. Liggitt, and A.Y. Rudensky Cellular mechanisms of fatal early-onset autoimmunity in mice with the T cell specific targeting of transforming growth factor-beta receptor Immunity 25 2006 441 454
-
(2006)
Immunity
, vol.25
, pp. 441-454
-
-
Marie, J.C.1
Liggitt, D.2
Rudensky, A.Y.3
-
20
-
-
0035168144
-
Sensory adaptation in naïve peripheral CD4 T cells
-
K. Smith, B. Seddon, M.A. Purbhoo, R. Zamoyska, A.G. Fisher, and M. Merkenschlager Sensory adaptation in naïve peripheral CD4 T cells J Exp Med 194 2001 1253 1261
-
(2001)
J Exp Med
, vol.194
, pp. 1253-1261
-
-
Smith, K.1
Seddon, B.2
Purbhoo, M.A.3
Zamoyska, R.4
Fisher, A.G.5
Merkenschlager, M.6
-
21
-
-
0035927093
-
Dynamic tuning of T cell reactivity by self-peptide-major histocompatibility complex ligands
-
P. Wong, G.M. Barton, K.A. Forbush, and A.Y. Rudensky Dynamic tuning of T cell reactivity by self-peptide-major histocompatibility complex ligands J Exp Med 193 2001 1179 1187
-
(2001)
J Exp Med
, vol.193
, pp. 1179-1187
-
-
Wong, P.1
Barton, G.M.2
Forbush, K.A.3
Rudensky, A.Y.4
-
22
-
-
25144476332
-
Independent roles for IL-2 and GATA-3 in stimulating naïve CD4+ T cells to generate a Th2- inducing cytokine environment
-
H. Yamane, J. Zhu, and W.E. Paul Independent roles for IL-2 and GATA-3 in stimulating naïve CD4+ T cells to generate a Th2- inducing cytokine environment J Exp Med 202 2005 793 804
-
(2005)
J Exp Med
, vol.202
, pp. 793-804
-
-
Yamane, H.1
Zhu, J.2
Paul, W.E.3
-
23
-
-
0032212793
-
Inhibition of Th1 development mediated by GATA-3 through an IL-4 independent mechanism
-
W. Ouyang, S.H. Ranganath, K. Weindel, D. Bhattacharya, T.L. Murphy, and W.C. Sha Inhibition of Th1 development mediated by GATA-3 through an IL-4 independent mechanism Immunity 9 1998 745 755
-
(1998)
Immunity
, vol.9
, pp. 745-755
-
-
Ouyang, W.1
Ranganath, S.H.2
Weindel, K.3
Bhattacharya, D.4
Murphy, T.L.5
Sha, W.C.6
-
24
-
-
0036305450
-
TH cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes
-
O. Avni, D. Lee, F. Macian, S.J. Szabo, L.H. Glimcher, and A. Rao TH cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes Nat Immunol 3 2002 643 651
-
(2002)
Nat Immunol
, vol.3
, pp. 643-651
-
-
Avni, O.1
Lee, D.2
Macian, F.3
Szabo, S.J.4
Glimcher, L.H.5
Rao, A.6
-
25
-
-
0035041537
-
Regulation of IL-4 gene expression by distal regulatory elements and GATA-3 at the chromatin level
-
G.R. Lee, P.E. Fields, and R.A. Flavell Regulation of IL-4 gene expression by distal regulatory elements and GATA-3 at the chromatin level Immunity 14 2001 447 459
-
(2001)
Immunity
, vol.14
, pp. 447-459
-
-
Lee, G.R.1
Fields, P.E.2
Flavell, R.A.3
-
26
-
-
0000344022
-
GATA-3 induces T helper cell type 2 (Th2) cytokine expression and chromatin remodeling in committed Th1 cells
-
H.J. Lee, N. Takemoto, H. Kurata, Y. Kamogawa, S. Miyatake, and A. O'Garra GATA-3 induces T helper cell type 2 (Th2) cytokine expression and chromatin remodeling in committed Th1 cells J Exp Med 192 2000 105 115
-
(2000)
J Exp Med
, vol.192
, pp. 105-115
-
-
Lee, H.J.1
Takemoto, N.2
Kurata, H.3
Kamogawa, Y.4
Miyatake, S.5
O'Garra, A.6
-
27
-
-
5444237577
-
Long-range intrachromosomal interactions in the T helper type 2 cytokine locus
-
C.G. Spilianakis, and R.A. Flavell Long-range intrachromosomal interactions in the T helper type 2 cytokine locus Nat Immunol 5 2004 1017 1027
-
(2004)
Nat Immunol
, vol.5
, pp. 1017-1027
-
-
Spilianakis, C.G.1
Flavell, R.A.2
-
28
-
-
33749338087
-
Transforming growth factor-β signaling through the Smad proteins: Role in systemic sclerosis
-
F. Verrecchia, A. Mauviel, and D. Farge Transforming growth factor-β signaling through the Smad proteins: role in systemic sclerosis Autoimmun Rev 5 2006 563 569
-
(2006)
Autoimmun Rev
, vol.5
, pp. 563-569
-
-
Verrecchia, F.1
Mauviel, A.2
Farge, D.3
-
29
-
-
9144219649
-
Cutting edge: TGF-β signaling is required for the in vivo expansion and immunosuppressive capacity of regulatory CD4+ CD25+ T cells
-
S. Huber, C. Schramm, H.A. Lehr, A. Mann, S. Schmitt, and C. Becker Cutting edge: TGF-β signaling is required for the in vivo expansion and immunosuppressive capacity of regulatory CD4+ CD25+ T cells J Immunol 173 2004 6526 6531
-
(2004)
J Immunol
, vol.173
, pp. 6526-6531
-
-
Huber, S.1
Schramm, C.2
Lehr, H.A.3
Mann, A.4
Schmitt, S.5
Becker, C.6
-
30
-
-
0348223787
-
Conversion of peripheral CD4+ CD25-naïve T cells to CD4+ CD25+ regulatory T cells by TGF-β induction of transcription factor Foxp3
-
W. Chen, W. Jin, N. Hardegen, K.J. Lei, L. Li, and N. Marinos Conversion of peripheral CD4+ CD25-naïve T cells to CD4+ CD25+ regulatory T cells by TGF-β induction of transcription factor Foxp3 J Exp Med 198 2003 1875 1886
-
(2003)
J Exp Med
, vol.198
, pp. 1875-1886
-
-
Chen, W.1
Jin, W.2
Hardegen, N.3
Lei, K.J.4
Li, L.5
Marinos, N.6
-
31
-
-
0024408824
-
Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones
-
D.F. Florentino, M.W. Bond, and T.R. Mosmann Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones J Exp Med 170 1989 2081 2095
-
(1989)
J Exp Med
, vol.170
, pp. 2081-2095
-
-
Florentino, D.F.1
Bond, M.W.2
Mosmann, T.R.3
-
32
-
-
0027521572
-
Interleukin-10-deficient mice develop chronic enterocolitis
-
R. Kuhn, J. Lohler, D. Rennick, K. Rajewsky, and W. Muller Interleukin-10-deficient mice develop chronic enterocolitis Cell 75 1993 263 274
-
(1993)
Cell
, vol.75
, pp. 263-274
-
-
Kuhn, R.1
Lohler, J.2
Rennick, D.3
Rajewsky, K.4
Muller, W.5
-
33
-
-
36248965294
-
TGF-β and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain T(H)-17 cell-mediated pathology
-
M.J. McGeachy, K.S. Bak-jensen, Y. Chen, C.M. Tato, W. Blumenschein, and T. McClanahan TGF-β and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain T(H)-17 cell-mediated pathology Nat Immunol 8 2007 1390 1397
-
(2007)
Nat Immunol
, vol.8
, pp. 1390-1397
-
-
McGeachy, M.J.1
Bak-jensen, K.S.2
Chen, Y.3
Tato, C.M.4
Blumenschein, W.5
McClanahan, T.6
-
34
-
-
36248951161
-
Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10
-
J.S. Stumhofer, J.S. Silver, A. Laurence, P.M. Porrett, T.H. Harris, and L.A. Turka Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10 Nat Immunol 8 2007 1363 1371
-
(2007)
Nat Immunol
, vol.8
, pp. 1363-1371
-
-
Stumhofer, J.S.1
Silver, J.S.2
Laurence, A.3
Porrett, P.M.4
Harris, T.H.5
Turka, L.A.6
-
35
-
-
20444485767
-
Cellular and genetic mechanisms of self tolerance and autoimmunity
-
C.C. Goodnow, J. Sprent, B.F. de St Groth, and C.G. Vinuesa Cellular and genetic mechanisms of self tolerance and autoimmunity Nature 435 2005 590 597
-
(2005)
Nature
, vol.435
, pp. 590-597
-
-
Goodnow, C.C.1
Sprent, J.2
De St Groth, B.F.3
Vinuesa, C.G.4
-
36
-
-
0033491193
-
CD95 APO-1/Fas-mediated apoptosis: Live and let die
-
P.H. Krammer CD95 APO-1/Fas-mediated apoptosis: live and let die Adv Immunol 71 1999 163 210
-
(1999)
Adv Immunol
, vol.71
, pp. 163-210
-
-
Krammer, P.H.1
-
37
-
-
0028927607
-
The Fas death factor
-
S. Nagata, and P. Golstein The Fas death factor Science 267 1995 1449 1456
-
(1995)
Science
, vol.267
, pp. 1449-1456
-
-
Nagata, S.1
Golstein, P.2
-
38
-
-
77953000914
-
Hematopoietic stem cell transplantation for profound T-cell deficiency (combined immunodeficiency)
-
C.M. Roifman Hematopoietic stem cell transplantation for profound T-cell deficiency (combined immunodeficiency) Immunol Allergy Clin North Am 30 2010 209 219
-
(2010)
Immunol Allergy Clin North Am
, vol.30
, pp. 209-219
-
-
Roifman, C.M.1
-
39
-
-
0029133646
-
Essential role for ZAP70 in both positive and negative selection of thymocytes
-
I. Negishi, N. Motoyama, K. Nakayama, K. Nakayama, S. Senju, and S. Hatakeyama Essential role for ZAP70 in both positive and negative selection of thymocytes Nature 376 1995 435 438
-
(1995)
Nature
, vol.376
, pp. 435-438
-
-
Negishi, I.1
Motoyama, N.2
Nakayama, K.3
Nakayama, K.4
Senju, S.5
Hatakeyama, S.6
-
40
-
-
0033197970
-
Pre-T cell receptor signals are responsible for the down-regulation of Syk protein tyrosine kinase expression
-
D.H. Chu, N.S. van Oers, M. Malissen, J. Harris, M. Elder, and A. Weiss Pre-T cell receptor signals are responsible for the down-regulation of Syk protein tyrosine kinase expression J Immunol 163 1999 2610 2620
-
(1999)
J Immunol
, vol.163
, pp. 2610-2620
-
-
Chu, D.H.1
Van Oers, N.S.2
Malissen, M.3
Harris, J.4
Elder, M.5
Weiss, A.6
-
41
-
-
0035159584
-
Distinct T cell developmental consequences in humans and mice expressing identical mutations in the DLAARN motif of ZAP70
-
M.E. Elder, S. Skoda-Smith, T.A. Kadlecek, F. Wang, J. Wu, and A. Weiss Distinct T cell developmental consequences in humans and mice expressing identical mutations in the DLAARN motif of ZAP70 J Immunol 166 2001 656 661
-
(2001)
J Immunol
, vol.166
, pp. 656-661
-
-
Elder, M.E.1
Skoda-Smith, S.2
Kadlecek, T.A.3
Wang, F.4
Wu, J.5
Weiss, A.6
-
42
-
-
0345414139
-
Altered thymic T cell selection due to a mutation of the Zap 70 gene causes autoimmune arthritis in mice
-
N. Sakaguchi, T. Takahashi, H. Hata, T. Nomura, T. Tagami, and S. Yamazaki Altered thymic T cell selection due to a mutation of the Zap 70 gene causes autoimmune arthritis in mice Nature 426 2003 454 460
-
(2003)
Nature
, vol.426
, pp. 454-460
-
-
Sakaguchi, N.1
Takahashi, T.2
Hata, H.3
Nomura, T.4
Tagami, T.5
Yamazaki, S.6
-
43
-
-
57049172523
-
Clinical heterogeneity can hamper the diagnosis of patients with ZAP 70 deficiency
-
T. Turul, I. Tezcan, H. Artac, S. de Bruin-Versteeg, B.H. Barendregt, and I. Reisli Clinical heterogeneity can hamper the diagnosis of patients with ZAP 70 deficiency Eur J Pediatr 168 2009 87 93
-
(2009)
Eur J Pediatr
, vol.168
, pp. 87-93
-
-
Turul, T.1
Tezcan, I.2
Artac, H.3
De Bruin-Versteeg, S.4
Barendregt, B.H.5
Reisli, I.6
-
44
-
-
0040905837
-
Existence of activated and memory CD4+ T cells in peripheral blood and their skin infiltration in CD8 deficiency
-
K. Katamura, G. Tai, T. Tachibana, H. Yamabe, K. Ohmori, and M. Mayumi Existence of activated and memory CD4+ T cells in peripheral blood and their skin infiltration in CD8 deficiency Clin Exp Immunol 115 1999 124 130
-
(1999)
Clin Exp Immunol
, vol.115
, pp. 124-130
-
-
Katamura, K.1
Tai, G.2
Tachibana, T.3
Yamabe, H.4
Ohmori, K.5
Mayumi, M.6
-
45
-
-
78649826926
-
A 3 yr old boy with ZAP-70 deficiency
-
D.E. Parry, J. Blumenthal, R.H. Tomar, S.D. Horowitz, M.E. Elder, and J.E. Gern A 3 yr old boy with ZAP-70 deficiency [abstract] J Allergy Clin Immunol 97 1996 A390
-
(1996)
J Allergy Clin Immunol
, vol.97
, pp. 390
-
-
Parry, D.E.1
Blumenthal, J.2
Tomar, R.H.3
Horowitz, S.D.4
Elder, M.E.5
Gern, J.E.6
|