Brain-specific delivery of naproxen using different carrier systems

Archiv der Pharmazie

Volumn 343, Issue 11-12, 2010, Pages 639-647

  Mahmoud, Sheha ^a   Mohammad, Alhawi ^a  

^a KING ABDULAZIZ UNIVERSITY   (Saudi Arabia)

Author keywords

Ascorbic acid; Bioavailability; Chemical delivery system; Naproxen prodrug

Indexed keywords

(1H BENZOTRIAZOL 1 YL)PYRIDIN 3 YL KETONE; 1 (1H BENZOTRIAZOL 1 YL) 2 (6 METHOXYNAPHTHALEN 2 YL)PROPAN 1 ONE; 1 CARBOXYMETHYL 3 [2 [2 (6 METHOXYNAPHTHALEN 2 YL)PROPIONYLAMINO]ETHOXYCARBONYL]PYRIDINIUM; 1 ETHOXYCARBONYLMETHYL 1,4 DIHYDROPYRIDINE 3 CARBOXYLICACID 2 [2 (6 METHOXYNAPHTHALEN 2 YL)PROPIONYLAMINO]ETHYL ESTER; 1 ETHOXYCARBONYLMETHYL 3 [2 [2 (6 METHOXYNAPHTHALEN 2 YL)PROPIONYLAMINO]ETHOXYCARBONYL]PYRIDINIUM BROMIDE; 1 ETHOXYCARBONYLMETHYL 3 [2 [2 (6 METHOXYNAPHTHALEN 2 YL)PROPIONYLOXY]ETHOXYCARBAMOYL]PYRIDINIUM BROMIDE; 2 (6 METHOXYNAPHTHALEN 2 YL)PROPIONICACID 2 (3,4 BIS BENZYLOXY 5 OXO 2,5 DIHYDROFURAN 2 YL) 2 HYDROXYETHYL ESTER; 2 (6 METHOXYNAPHTHALEN 2 YL)PROPIONICACID 2 (3,4 DIHYDROXY 5 OXO 2,5 DIHYDROFURAN 2 YL) 2 HYDROXYCARBONYLMETHYL ESTER; 2 (6 METHOXYNAPHTHALEN 2 YL)PROPIONICACID 2 (3,4 DIHYDROXY 5 OXO 2,5 DIHYDROFURAN 2 YL) 2 HYDROXYETHYL ESTER; 2 (6 METHOXYNAPHTHALEN 2YL)PROPIONIC ACID 2 [(1 ETHOXYCARBONYLMETHYL 1,4 DIHYDROPYRIDINE 3 CARBONYL)AMINO]ETHYL ESTER; 2 [2 (6 METHOXY NAPHTHALEN 2 YL)PROPIONYLAMINO]ETHYLNICOTINIC ACID ESTER; ASCORBIC ACID; BUFFER; CARBOXYLIC ACID; DIHYDROPYRIDINE; DRUG CARRIER; ETHANOLAMINE; N (2 HYDROXYETHYL) 2 (6 METHOXYNAPHTHALEN 2 YL)PROPIONAMIDE; N (2 HYDROXYETHYL)NICOTINAMIDE; NAPROXEN; PRODRUG; PYRIDINIUM DERIVATIVE; SODIUM; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; AQUEOUS SOLUTION; ARTICLE; BLOOD BRAIN BARRIER; BODY FLUID; BRAIN SPECIFIC DELIVERY; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG CLEARANCE; DRUG DELIVERY SYSTEM; DRUG HALF LIFE; DRUG TRANSPORT; HUMAN; HYDROLYSIS; LIPOPHILICITY; MALE; NONHUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; RAT;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ASCORBIC ACID; BODY FLUIDS; BRAIN; CYCLOOXYGENASE INHIBITORS; DIHYDROPYRIDINES; DRUG CARRIERS; HUMANS; HYDROLYSIS; NAPROXEN; PRODRUGS; SOLUTIONS;

EID: 78649885660     PISSN: 03656233     EISSN: 15214184     Source Type: Journal    
DOI: 10.1002/ardp.201000105     Document Type: Article

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