A detailed mathematical model predicts that serial engagement of IgE-FcεRI complexes can enhance Syk activation in mast cells

Journal of Immunology

Volumn 185, Issue 6, 2010, Pages 3268-3276

  Nag, Ambarish ^a,c   Monine, Michael I ^a,d   Blinov, Michael L ^b   Goldstein, Byron ^a  

^a LOS ALAMOS NATIONAL LABORATORY   (United States)

^b UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

^c NATIONAL RENEWABLE ENERGY LABORATORY   (United States)

^d Biotechnology High Performance Computing Software Applications Institute   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FC RECEPTOR; IMMUNOGLOBULIN E FC EPSILON RECEPTOR; PROTEIN KINASE SYK; UNCLASSIFIED DRUG;

ARTICLE; IMMUNE RESPONSE; MAST CELL; MATHEMATICAL MODEL; PRIORITY JOURNAL; PROTEIN CROSS LINKING; PROTEIN PHOSPHORYLATION;

ANIMALS; BINDING SITES, ANTIBODY; CELL LINE, TUMOR; ENZYME ACTIVATION; IMMUNOGLOBULIN E; IMMUNOGLOBULIN FRAGMENTS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LEUKEMIA, BASOPHILIC, ACUTE; LIGANDS; LYMPHOCYTE ACTIVATION; MAST CELLS; MODELS, IMMUNOLOGICAL; PREDICTIVE VALUE OF TESTS; PROTEIN TRANSPORT; PROTEIN-TYROSINE KINASES; RATS; RECEPTORS, IGE; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 78649871736     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1000326     Document Type: Article

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