CAMP and fibroblast growth factor 2 regulate bone sialoprotein gene expression in human prostate cancer cells

Gene

Volumn 471, Issue 1-2, 2011, Pages 1-12

  Li, Zhengyang ^a,b   Sasaki, Yoko ^a   Mezawa, Masaru ^a   Wang, Shuang ^a,b   Li, Xinyue ^a,c   Yang, Li ^a,b   Wang, Zhitao ^a,b   Zhou, Liming ^a,d   Araki, Shouta ^a   Matsumura, Hiroyoshi ^a   Takai, Hideki ^a   Ogata, Yorimasa ^a  

^a NIHON UNIVERSITY   (Japan)

^b TIANJIN STOMATOLOGICAL HOSPITAL   (China)

^c TIANJIN MEDICAL UNIVERSITY   (China)

^d Anhui Province Stomatology Hospital   (China)

Author keywords

Bone sialoprotein; CAMP; FGF2; Prostate cancer; Transcription

Indexed keywords

ADENYLATE CYCLASE; BONE SIALOPROTEIN; CRE RECOMBINASE; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; FIBROBLAST GROWTH FACTOR 2; FORSKOLIN; HYDROXYAPATITE; LUCIFERASE; MESSENGER RNA; PROTEIN C FOS; PROTEIN C JUN; PROTEIN P300; PROTEIN TYROSINE KINASE INHIBITOR; SMAD1 PROTEIN; TRANSCRIPTION FACTOR DLX5; TRANSCRIPTION FACTOR FRA 2; TRANSCRIPTION FACTOR RUNX2;

ARTICLE; CANCER CELL CULTURE; CELL DIFFERENTIATION; CELL PROLIFERATION; COMPLEX FORMATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYCLIC AMP RESPONSIVE ELEMENT; ENZYME ACTIVITY; GEL MOBILITY SHIFT ASSAY; GENE CONSTRUCT; GENE DISRUPTION; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE MUTATION; HUMAN; HUMAN CELL; HUMAN TISSUE; OSTEOBLAST; PRIORITY JOURNAL; PROMOTER REGION; PROSTATE CANCER; PROTEIN PROTEIN INTERACTION; REPORTER GENE; TRANSIENT TRANSFECTION;

BASE SEQUENCE; CELL LINE, TUMOR; CHROMATIN; CORE BINDING FACTOR ALPHA 1 SUBUNIT; CYCLIC AMP; DNA PRIMERS; FIBROBLAST GROWTH FACTOR 2; FORSKOLIN; GENE EXPRESSION REGULATION, NEOPLASTIC; GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASES; HUMANS; INTEGRIN-BINDING SIALOPROTEIN; MALE; PROSTATIC NEOPLASMS; TRANSFECTION;

EID: 78649868168     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.gene.2010.09.009     Document Type: Article

References (56)

1. Araki S., et al. Parathyroid hormone regulation of the human bone sialoprotein gene transcription is mediated through two cAMP response elements. J. Cell. Biochem. 2009, 106:618-625.
2. Barnes G., et al. Osteoblast-related transcription factors Runx2 (Cbfa1/AML3) and MSX2 mediate the expression of bone sialoprotein in human metastatic breast cancer cells. Cancer Res. 2003, 63:2631-2637.
3. Benson M.D., Aubin J.E., Xiao G., Thomas P.E., Franceschi R.T. Cloning of a 2.5kb murine bone sialoprotein promoter fragment and functional analysis of putative Osf2 binding sites. J. Bone Miner. Res. 1999, 14:396-405.
4. Benson M.D., et al. Identification of a homeodomain binding element in the bone sialoprotein gene promoter that is required for its osteoblast-selective expression. J. Biol. Chem. 2000, 275:13907-13917.
5. Bianco P., Fisher L.W., Young M.F., Termine J.D., Robey P.G. Expression of bone sialoprotein (BSP) in developing human tissues. Calcif. Tissue Int. 1991, 49:421-426.
6. Brown L.F., et al. Osteopontin expression and distribution in human carcinomas. Am. J. Pathol. 1994, 145:610-623.
7. Busca R., et al. Ras mediates the cAMP-dependent activation of extracellular signal-regulated kinases (ERKs) in melanocytes. EMBO J. 2000, 19:2900-2910.
8. Carlinfante G., Vassiliou D., Svensson O., Wendel M., Heinegard D., Andersson G. Differential expression of osteopontin and bone sialoprotein in bone metastasis of breast and prostate carcinoma. Clin. Exp. Metastasis 2003, 20:437-444.
9. Chung L.W. Prostate carcinoma bone-stroma interaction and its biologic and therapeutic implications. Cancer 2003, 97:772-778.
10. Coffin J.D., et al. Abnormal bone growth and selective translational regulation in basic fibroblast growth factor (FGF-2) transgenic mice. Mol. Biol. Cell 1995, 6:1861-1873.
11. Curatolo C., et al. Advanced prostate cancer follow-up with prostate-specific antigen, prostatic acid phosphatase, osteocalcin and bone isoenzyme of alkaline phosphatase. Eur. Urol. 1992, 21(Suppl 1):105-107.
12. Daly J.W., Padgett W., Seamon K.B. Activation of cyclic AMP-generating systems in brain membranes and slices by the diterpene forskolin: augmentation of receptor-mediated responses. J. Neurochem. 1982, 38:532-544.
13. de Rooij J., et al. Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP. Nature 1998, 396:474-477.
14. Detry C., Lamour V., Castronovo V., Bellahcene A. CREB-1 and AP-1 transcription factors JunD and Fra-2 regulate bone sialoprotein gene expression in human breast cancer cells. Bone 2008, 42:422-431.
15. Dignam J.D., Lebovitz R.M., Roeder R.G. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 1983, 11:1475-1489.
16. Drissi M.H., et al. Runx2/Cbfa1 stimulation by retinoic acid is potentiated by BMP2 signaling through interaction with Smad1 on the collagen X promoter in chondrocytes. J. Cell. Biochem. 2003, 90:1287-1298.
17. Fedarko N.S., Fohr B., Robey P.G., Young M.F., Fisher L.W. Factor H binding to bone sialoprotein and osteopontin enables tumor cell evasion of complement-mediated attack. J. Biol. Chem. 2000, 275:16666-16672.
18. Frodin M., et al. Glucose, other secretagogues, and nerve growth factor stimulate mitogen-activated protein kinase in the insulin-secreting beta-cell line, INS-1. J. Biol. Chem. 1995, 270:7882-7889.
19. Ganss B., Kim R.H., Sodek J. Bone sialoprotein. Crit. Rev. Oral Biol. Med. 1999, 10:79-98.
20. Greenlee R.T., Murray T., Bolden S., Wingo P.A. Cancer statistics, 2000. CA Cancer J. Clin. 2000, 50:7-33.
21. Heldin C.H., Miyazono K., ten Dijke P. TGF-beta signaling from cell membrane to nucleus through SMAD proteins. Nature 1997, 390:465-471.
22. Huang W.C., Xie Z., Konaka H., Sodek J., Zhau H.E., Chung L.W. Human osteocalcin and bone sialoprotein mediating osteomimicry of prostate cancer cells: role of cAMP-dependent protein kinase A signaling pathway. Cancer Res. 2005, 65:2303-2313.
23. Hunter G.K., Goldberg H.A. Nucleation of hydroxyapatite by bone sialoprotein. Proc. Natl. Acad. Sci. USA 1993, 90:8562-8565.
24. Insel P.A., Ostrom R.S. Forskolin as a tool for examining adenylyl cyclase expression, regulation, and G protein signaling. Cell. Mol. Neurobiol. 2003, 23:305-314.
25. Kerr J.M., Fisher L.W., Termine J.D., Wang M.G., McBride O.W., Young M.F. The human bone sialoprotein gene (IBSP): genomic localization and characterization. Genomics 1993, 17:408-415.
26. Kim R.H., Sodek J. Transcription of the bone sialoprotein gene is stimulated by v-Src acting through an inverted CCAAT box. Cancer Res. 1999, 59:565-571.
27. Kim R.H., Shapiro H.S., Li J.J., Wrana J.L., Sodek J. Characterization of the human bone sialoprotein (BSP) gene and its promoter sequence. Matrix Biol. 1994, 14:31-40.
28. Kiyoshima T., Yamauchi M., Wong C., Jheon A., Ganss B., Sodek J. An L1 element disrupts human bone sialoprotein promoter: lack of tissue-specific regulation by distalless5 (Dlx5) and runt homeodomain protein2 (Runx2)/core binding factor a1 (Cbfa1) elements. Gene 2002, 299:205-217.
29. Koeneman K.S., Yeung F., Chung L.W. Osteomimetic properties of prostate cancer cells: a hypothesis supporting the predilection of prostate cancer metastasis and growth in the bone environment. Prostate 1999, 39:246-261.
30. Lang S.H., Clarke N.W., George N.J., Allen T.D., Testa N.G. Interaction of prostate epithelial cells from benign and malignant tumor tissue with bone-marrow stroma. Prostate 1998, 34:203-213.
31. Lee M.H., et al. BMP-2-induced Runx2 expression is mediated by Dlx5, and TGF-β1 opposes the BMP-2-induced osteoblast differentiation by suppression of Dlx5 expression. J. Biol. Chem. 2003, 278:34387-34394.
32. Li J.J., Sodek J. Cloning and characterization of the rat bone sialoprotein gene promoter. Biochem. J. 1993, 289:625-629.
33. Liu Y., Wang J.L., Chang H., Barsky S.H., Nguyen M. Breast-cancer diagnosis with nipple fluid bFGF. Lancet 2000, 356:567.
34. Martinez J., Silva S., Santibanez J.F. Prostate-derived soluble factors block osteoblast differentiation in culture. J. Cell. Biochem. 1996, 61:18-25.
35. Mason I.J. The ins and outs of fibroblast growth factors. Cell 1994, 78:547-552.
36. Mezawa M., et al. Regulation of human bone sialoprotein gene transcription by platelet-derived growth factor-BB. Gene 2009, 435:80-87.
37. Mintz K.P., Grzesik W.J., Midura R.J., Robey P.G., Termine J.D., Fisher L.W. Purification and fragmentation of nondenatured bone sialoprotein: evidence for a cryptic, RGD-resistant cell attachment domain. J. Bone Miner. Res. 1993, 8:985-995.
38. Montero A., et al. Disruption of the fibroblast growth factor-2 gene results in decrease bone mass and bone formation. J. Clin. Invest. 2000, 105:1085-1093.
39. Nakayama Y., et al. Insulin-like growth factor-I increases bone sialoprotein (BSP) expression through fibroblast growth factor-2 response element and homeodomain protein-binding site in the proximal promoter of the BSP gene. J. Cell. Physiol. 2006, 208:326-335.
40. Ogata Y. Bone sialoprotein and its transcriptional regulatory mechanism. J. Periodontal Res. 2008, 43:127-135.
41. Penault-Llorca F., et al. Exzpression of FGF and FGF receptor genes in human breast cancer. Int. J. Cancer 1995, 61:170-176.
42. Ross F.P., et al. Interactions between the bone matrix proteins osteopontin and bone sialoprotein and the osteoclast integrin alpha v beta 3 potentiate bone resorption. J. Biol. Chem. 1993, 268:9901-9907.
43. Ryoo H.M., et al. Stage-specific expression of Dlx-5 during osteoblast differentiation: involvement in regulation of osteocalcin gene expression. Mol. Endocrinol. 1997, 11:1681-1694.
44. Sassone-Corsi P. Transcription factors responsive to cAMP. Annu. Rev. Cell Dev. Biol. 1995, 11:355-377.
45. Seamon K.B., Daly J.W. Forskolin: a unique diterpene activator of cyclic AMP-generating systems. J. Cyclic Nucleotide Res. 1981, 7:201-224.
46. Seamon K.B., Padgett W., Daly J.W. Forskolin: unique diterpene activator of adenylate cyclase in membranes and in intact cells. Proc. Natl. Acad. Sci. USA 1981, 78:3363-3367.
47. Shimizu E., et al. Fibroblast growth factor 2 and cyclic AMP synergistically regulate bone sialoprotein gene expression. Bone 2006, 39:42-52.
48. Shimizu-Sasaki E., Yamazaki M., Furuyama S., Sugiya H., Sodek J., Ogata Y. Identification of a novel response element in the rat bone sialoprotein (BSP) gene promoter that mediates constitutive and fibroblast growth factor 2-induced expression of BSP. J. Biol. Chem. 2001, 276:5459-5466.
49. Sierra J., et al. Regulation of the bone-specific osteocalcin gene by P300 requires Runx2/Cbfa1 and the vitamin D3 receptor but not P300 intrinsic histone acetyltransferase activity. Mol. Cell. Biol. 2003, 23:3339-3351.
50. Simeone A., et al. Cloning and characterization of two members of the vertebrate Dlx gene family. Proc. Natl. Acad. Sci. USA 1994, 91:2250-2254.
51. Takai H., et al. AP1 binding site is another target of FGF2 regulation of bone sialoprotein gene transcription. Gene 2008, 410:97-104.
52. Waltregny D., et al. Prognostic value of bone sialoprotein expression in clinically localized human prostate cancer. J. Natl. Cancer Inst. 1998, 90:1000-1008.
53. Waltregny D., Bellahcene A., de Leval X., Florkin B., Weidle U., Castronovo V. Increased expression of bone sialoprotein in bone metastases compared with visceral metastases in human breast and prostate cancers. J. Bone Miner. Res. 2000, 15:834-843.
54. Yamasaki M., Miyake A., Tagashira S., Itho N. Structure and expression of the rat mRNA encoding a novel member of the fibroblast growth factor family. J. Biol. Chem. 1996, 271:15918-15921.
55. Yeung F., et al. Regulation of human osteocalcin promoter in hormone-independent human prostate cancer cells. J. Biol. Chem. 2002, 277:2468-2476.
56. Zhang J.H., et al. Over-expression of bone sialoprotein enhances bone metastasis of human breast cancer cells in a mouse model. Int. J. Oncol. 2003, 23:1043-1048.