TCR-induced activation of Ras proceeds at the plasma membrane and requires palmitoylation of N-Ras

Journal of Immunology

Volumn 185, Issue 6, 2010, Pages 3536-3543

  Rubio, Ignacio ^a   Grund, Stefan ^a,d   Song, Shu Ping ^a   Biskup, Christoph ^a   Bandemer, Sabine ^a   Fricke, Melanie ^a   Förster, Martin ^a   Graziani, Andrea ^c   Wittig, Ute ^a   Kliche, Stefanie ^b  

^a JENA UNIVERSITY HOSPITAL   (Germany)

^b OTTO VON GUERICKE UNIVERSITY   (Germany)

^c UNIVERSITY OF EASTERN PIEDMONT   (Italy)

^d FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DIACYLGLYCEROL; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; MUTANT PROTEIN; PROTEIN; PROTEIN N RAS; RAS PROTEIN; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CELL MEMBRANE; CONTROLLED STUDY; ENZYME ACTIVATION; GENE OVEREXPRESSION; GOLGI COMPLEX; IMMUNOLOGICAL SYNAPSE; LEUKEMIA CELL LINE; MOLECULAR INTERACTION; MOLECULAR PROBE; PALMITOYLATION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; T LYMPHOCYTE;

ANIMALS; CELL LINE, TUMOR; CELL MEMBRANE; DNA-BINDING PROTEINS; ENDOPLASMIC RETICULUM; FLUORESCENT DYES; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; JURKAT CELLS; LIPOYLATION; ONCOGENE PROTEIN P21(RAS); PROTEIN BINDING; PROTEIN TRANSPORT; RAS GUANINE NUCLEOTIDE EXCHANGE FACTORS; RAS PROTEINS; RATS; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; T-LYMPHOCYTE SUBSETS;

EID: 78649862797     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1000334     Document Type: Article

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