Reproductive toxicity of Echinodorus grandiflorus in pregnant rats

Journal of Toxicological Sciences

Volumn 35, Issue 6, 2010, Pages 911-922

  Brugiolo, Sônia Sin Singer ^a   Peters, Vera Maria ^a,b   Pimenta, Daniel Sales ^b   Aarestrup, Beatriz Julião Vieira ^a,b   Brugiolo, Alessa Sin Singer ^b   Ribeiro, Dayana Mendes ^b   Guerra, Martha De Oliveira ^a,b  

^a Departamento de Fisioterapia   (Brazil)

^b FEDERAL UNIVERSITY OF JUIZ DE FORA   (Brazil)

Author keywords

Echinodorus grandiflorus; Histopathology; Rats; Toxicity

Indexed keywords

ASPARTATE AMINOTRANSFERASE; CHOLESTEROL; ECHINODORUS GRANDIFLORUS EXTRACT; HEMOSIDERIN; PLANT EXTRACT; UNCLASSIFIED DRUG;

ALISMATACEAE; ANEMIA; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ECHINODORUS GRANDIFLORUS; FEMALE; FETUS; FETUS DEATH; FETUS WEIGHT; HEMATOLOGICAL PARAMETERS; HEPATITIS; HYALINE DEGENERATION; LEUKOCYTOSIS; NEPHROTOXICITY; NONHUMAN; ORGAN WEIGHT; PLACENTA WEIGHT; PLANT LEAF; PREGNANCY; RAT; REPRODUCTIVE TOXICITY; SPLEEN; VASODILATATION; WEIGHT GAIN;

ANIMALIA; ECHINODORUS GRANDIFLORUS; RATTUS;

EID: 78649836373     PISSN: 03881350     EISSN: 18803989     Source Type: Journal    
DOI: 10.2131/jts.35.911     Document Type: Article

References (36)

1. Almeida, F.C.G. and Lemonica, I.P. (2000): The toxic effects of Coleus barbatus B. on the different periods of pregnancy in rats. J. Ethnopharmacol., 73, 53-60.
2. Burdan, F., Szumilo, J. and Klepacz, R. (2009): Maternal toxicity of nonsteroidal anti-inflammatory drugs as an important factor affecting prenatal development. Reprod. Toxicol., 28, 239-244.
3. Brugiolo S.S.S., Borges, L.V., Pimenta, D.S., Brugioro, A.S.S., Peters, V.M. and Guerra, M.O. (2009): Ethnobotany and Experimental Pharmacology of Echinodorus grandiflorus (chapéu-decouro). In: Medicinal Plants: Classification, Biosynthesis and Pharmacology (Alejandro, V. and Jasiah, I., eds.), pp.243-254, Nova Science Publishers, New York.
4. Calixto, J.B. (2000): Efficacy, safety, quality control, marketing and regulatory guidelines for herbal medicines (phytotherapeutic agents). Braz. J. Med. Biol. Res., 33, 179-189.
5. Calliari-Martin, M.R., Dietrich, S., Bortolini, C.E., Cunha, C.T. and Lorenceti, G.(2001): Embriotoxicidade da Artemisia vulgaris Linné em ratas. Revista Médica HSVP, 11, 12-17.
6. Cardoso, G.L.C., Pereira, N.A. and Lainetti, R. (2003): Avaliação das atividades antinociceptiva, antiinflamatória e diurética de chapéu de couro (Echinodorus grandiflorus, [Cham. e Schl.] Mitch. Alismataceae). Ver. Bras. Farm., 84, 5-7.
7. Cardoso, G.L.C., Pereira, N.A. and Laineti, R. (2005): Avaliação da atividade do chapéu de couro (Echinodorus grandiflorus) (Cham. & Schl.) Mitch. (Alismataceae) sobre os níveis plasmáticos de colesterol em camundongos. Rev. Bras. Farm., 86, 95-96.
8. Chahoud, I., Ligensa, A., Dietzel, L. and Faqi, A.S. (1999): Correlation between maternal toxicity and embryo/fetal effects. Reprod. Toxicol., 13, 375-381.
9. Chernoff, N., Rogers, J.M. and Kavlock, R.J. (1989): An overview of maternal toxicity and prenatal development: considerations for developmental toxicity hazard assessments. Toxicology, 59, 111-125. (Pubitemid 19270040)
10. Christian, M.S. (2001): Test methods for assessing female reproductive and developmental toxicology. In: Principles and Methods of Toxicology. (Hayes, W.A., ed.), pp.1301-1381, Taylor & Francis, Philadelphia.
11. Duarte, M.G.R., Soares, I.A.A., Brandão, M., Jácome, R.L.R.P., Ferreira, M.D., Silva, C.R.F. and Oliveira, A.B.T. (2002): Perfil fitoquímico e atividade antibacteriana in vitro de plantas invasoras. Rev. Lecta, Bragança Paulista, 20, 177-182.
12. Dutra, R.C., Tavares, C.Z., Ferraz, S.O., Sousa, O.V. and Pimenta, D.S. (2006): Investigação das atividades analgésica e anti-inflamatória de extrato metanólico dos rizomas de Echinodorus grandiflorus. Rev. Bras. Farmacogn., 16, 469-474.
13. Ergaz, Z., Avgil, M. and Ornoy, A. (2005): Intrauterine growth restriction - etiology and consequences: what do we know about the human situation and experimental animal models? Reprod. Toxicol., 20, 301-322. (Pubitemid 40943553)
14. Failace, R. (1992): Hemograma - manual de interpretação. Artes Médicas, Porto Alegre.
15. Finco, D.R. (1997): Kidney functions. In: Clinical biochemistry of domestic animals (Kaneko, J.J., Harvey, J.M. and Bruss, M.L. eds.), pp.441-484, Academic Press, San Diego.
16. Gortner, L., Hilgendorff, A., Bähner, T., Ebsen, M., Reiss, I. and Rudloff, S. (2005): Hypoxia-Induced Intrauterine Growth Retardation: Effects on Pulmonary Development and Surfactante Protein Transcription. Biol. Neonate, 88, 129-135.
17. Hood, R.D. (2006): Developmental and reproductive toxicology: a pratical approach. 2 ed. Taylor & Francis, London.
18. Hutchinson, F.N. and Jones, W.J. (1997): A cost-effectiveness analysis of anemia screening before erythropoietin in patients with end-stage renal disease. Am. J. Kidney Dis., 29, 651-657.
19. ICH (International Conference on Harmonisation of Technical Requirement for Registration of Pharmaceuticals for Human Use). ICH Harmonised Tripartite Guideline S5(R2): detection of toxicity to reproduction for medical products and toxicity for male fertility; 2005.
20. Khera, K.S. (1984): Maternal toxicity - a possible factor in fetal malformation in mice. Teratology, 29, 411-416.
21. Khera, K.S. (1985): Maternal toxicity: a possible etiological factor in embryo-fetal deaths and fetal malformations of rodent-rabbit species. Teratology, 31, 129-153.
22. Kavlock, R.J., Logsdon, T. and Gray, J.A. (1993): Fetal development in the rat following disruption of maternal renal function during pregnancy. Teratology, 48, 247-258. (Pubitemid 23271713)
23. Lessa, M.A., Araújo, C.V., Kaplan, M.A., Pimenta, D., Figueiredo, M.R. and Tibiriçá, E. (2008): Antihypertensive effects of crude extracts from leaves of Echinodorus grandiflorus. Fundam. Clin. Pharmacol., 22, 161-168.
24. Lopes L.C., Albano, F., Laranja G.A.T., Marques A.L, Fernando, M.S.L., Poubel, S.G, de Magalhães, A.I., Firmino Nogueira-Neto J., Felzenszwalb, I. and Kovary, K. (2000): Toxicological evaluation by in vitro and in vivo assays of an aqueous extract prepared from Echinodorus macrophyllus leaves. Toxicol. Lett., 116, 189-198.
25. Marcondes, F.K., Bianchi, F.J. and Tanno, A.P. (2002): Determination of the estrous cycle phases of rats: some helpful considerations. Braz. J. Biol., 62, 609-614.
26. Matos, F.J.A. (1997): Introdução à Fitoquímica Experimental. Edições UFC, Fortaleza, 45-64.
27. Miranda, S.P., Macedo, R.N., Silva, J., Geraldo, B. and Daher, E.F. (2009): Síndrome cardiorrenal: fisiopatologia e tratamento. Rev. Assoc. Med. Bras., 55, 89-94.
28. Moreti, D.L.C., Martins, C.H.G., Alves, E.G. Prado, F.O., Paz, K., Regis, G.C., Lopes, R.A. and Sala, M.A. (2006): Estudo hematológico em ratos sob ação de plantas medicinais. Echinodorus macrophyllus (Kunth.) Mitch. Rev. Bras. Pl. Med., Botucatu, 8, 162-164.
29. Pinto, A.C., Rego, G.C., Siqueira, A.M., Cardoso, C.C., Reis, P.A., Marques, E.A., Coelho, M.G. and de Carvalho Sabino, K.C. (2007): Immunosuppressive effects of Echinodorus macrophyllus aqueous extract. J. Ethnopharmacol., 111, 435-439.
30. Ribeiro, R.A., Fiuza, M.M.M., De Barros, F., Gomes, C. and Trolin, G. (1986): Acute antihypertensive effects in conscious rats produced by some medicinal plants used in the state of São Paulo. J. Ethnopharmacol., 15, 261-269.
31. Secretaria de Estado de Saúde (2002): Diário Oficial do Estado do Rio de Janeiro. Resolução SES/RJ No 1757, de 18 de fevereiro de 2002. Ano XXVII, no 3, parte I.
32. Schenkel, E.P, Zannin, M., Mentz, L.A, Bordignon, S.A.L. and Irgang, B. (2000): Plantas tóxicas. In Farmacognosia: da planta ao medicamento. (Simões, C.M.O., Schenkel, E.P, Gosmann G., Mello J.C.P., Mentz L.A. and Petrovick, P.R. eds.), pp.755-788, Porto Alegre: Editora da Universidade/UFRGS e Florianópolis: Editora da UFSC.
33. Silva, C.J., Bastos, J.K. and Takahashi, C.S. (2010): Evaluation of the genotoxic and cytotoxic effects of crude extracts of Cordia ecalyculata and Echinodorus grandiflorus. J. Ethnopharmacol., 127, 445-450.
34. Souza, G.C., Haas, A.P., von Poser, G.L., Schapoval, E.E. and Elisabetsky, E. (2004): Ethnopharmacological studies of antimicrobial remedies in the south of Brazil. J. Ethnopharmacol., 90, 135-143.
35. Smith, J.V. and Luo, Y. (2004): Studies on molecular mechanisms of Ginkgo biloba extract. Appl. Microbiol. Biotechnol., 64, 465-472.
36. Tibiriçá E., Almeida A.L.F., Caillleaux, S., Pimenta, D., Auxiliadora, K.M., Lessa, M.A. and Raquel Figueiredo, M. (2007): Pharmacological mechanisms involved in the vasodilator effects of extracts from Echinodorus grandiflorus. J. Ethnopharmacol. 111, 50-55.