Application of a liquid chromatography/tandem mass spectrometry method to pharmacokinetic study of mangiferin in rats

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 878, Issue 32, 2010, Pages 3345-3350

  Liu, Yiming ^a   Xu, Fuping ^a   Zeng, Xing ^a   Yang, Liu ^a   Deng, Yuanhui ^a   Wu, Zhifeng ^a   Feng, Yi ^a   Li, Xiong ^a  

^a GUANGDONG PROVINCIAL HOSPITAL OF CHINESE MEDICINE   (China)

Author keywords

LC MS MS; Mangiferin; Pharmacokinetics; Rat plasma

Indexed keywords

CHROMATOGRAPHIC SEPARATIONS; CONCENTRATION RANGES; DOSE LEVELS; ELECTROSPRAY IONIZATION TANDEM MASS SPECTROMETRY; INTERNAL STANDARDS; INTRAGASTRIC ADMINISTRATION; ISOCRATIC ELUTION; LC/MS/MS; LIQUID CHROMATOGRAPHY/TANDEM MASS SPECTROMETRY; MANGIFERIN; PARACETAMOL; PHARMACOKINETIC PROFILES; PHARMACOKINETIC STUDIES; PLASMA SAMPLES; PROTEIN PRECIPITATION; RAT PLASMA; TURBOIONSPRAY IONIZATION;

ACETIC ACID; ACETONITRILE; CHROMATOGRAPHY; ELECTROSPRAY IONIZATION; HIGH PRESSURE LIQUID CHROMATOGRAPHY; IONIZATION; LIQUIDS; MASS SPECTROMETRY; METHANOL; PHARMACOKINETICS; PLASMA (HUMAN); PLASMAS; RATS;

DRUG PRODUCTS;

ACETIC ACID; ACETONITRILE; MANGIFERIN; METHANOL; PARACETAMOL; PROTEIN;

ACCURACY; ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG DOSE INCREASE; DRUG STABILITY; ELECTROSPRAY MASS SPECTROMETRY; ELUTION; HUANGBAI; LIQUID CHROMATOGRAPHY; MAXIMUM PLASMA CONCENTRATION; MEDICINAL PLANT; NONHUMAN; PHARMACOLOGICAL PARAMETERS; PRECIPITATION; PRIORITY JOURNAL; RAT; SENSITIVITY AND SPECIFICITY; SINGLE DRUG DOSE; TANDEM MASS SPECTROMETRY; TIME TO MAXIMUM PLASMA CONCENTRATION; ZHIMU;

ANALYSIS OF VARIANCE; ANIMALS; AREA UNDER CURVE; CHROMATOGRAPHY, LIQUID; DRUG STABILITY; LINEAR MODELS; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY; XANTHONES;

RATTUS;

EID: 78649831450     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2010.10.014     Document Type: Article

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