Effects of aging on the cerebrovascular orthostatic response

Neurobiology of Aging

Volumn 32, Issue 2, 2011, Pages 344-353

  Kim, Yu Sok ^a   Bogert, Lysander W J ^a   Immink, Rogier V ^a   Harms, Mark P M ^a,b   Colier, Willy N J M ^c   Van Lieshout, Johannes J ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^c Artinis Medical Systems   (Netherlands)

Author keywords

Aging; Cerebral circulation; Hemodynamics; Near infrared spectroscopy; Orthostasis; Oxygenation; Transcranial Doppler

Indexed keywords

ADULT; AGE; AGED; AGING; ARTICLE; BLOOD FLOW VELOCITY; BODY POSTURE; BRAIN BLOOD FLOW; BRAIN CIRCULATION; BRAIN OXYGEN CONSUMPTION; BRAIN PERFUSION; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN EXPERIMENT; MALE; MEAN ARTERIAL PRESSURE; MIDDLE CEREBRAL ARTERY; NORMAL HUMAN; ORTHOSTATIC STRESS; PRIORITY JOURNAL;

ADAPTATION, PHYSIOLOGICAL; ADULT; AGED; AGING; ANALYSIS OF VARIANCE; BLOOD FLOW VELOCITY; CEREBROVASCULAR CIRCULATION; FEMALE; HOMEOSTASIS; HUMANS; MALE; MIDDLE AGED; MIDDLE CEREBRAL ARTERY; POSTURE; SPECTROSCOPY, NEAR-INFRARED; ULTRASONOGRAPHY, DOPPLER, TRANSCRANIAL;

EID: 78649827429     PISSN: 01974580     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2009.02.019     Document Type: Article

References (52)

1. Aaslid R., Lindegaard K.F., Sorteberg W., Nornes H. Cerebral autoregulation dynamics in humans. Stroke 1989, 20(1):45-52.
2. Al-Rawi P.G., Smielewski P., Kirkpatrick P.J. Evaluation of a near-infrared spectrometer (NIRO 300) for the detection of intracranial oxygenation changes in the adult head. Stroke 2001, 32(11):2492-2500.
3. American Geriatrics Society British Geriatrics Society and American Academy of Orthopaedic Surgeons Panel on Falls Prevention Guideline for the prevention of falls in older persons. J. Am. Geriatr. Soc. 2001, 49(5):664-672.
4. Bishop C.C., Powell S., Rutt D., Browse N.L. Transcranial Doppler measurement of middle cerebral artery blood flow velocity: a validation study. Stroke 1986, 17(5):913-915.
5. Bode H. Cerebral blood flow velocities during orthostasis and physical exercise. Eur. J. Pediatr. 1991, 150(10):738-743.
6. Campbell A.J., Spears G.F., Borrie M.J. Examination by logistic regression modelling of the variables which increase the relative risk of elderly women falling compared to elderly men. J. Clin. Epidemiol. 1990, 43(12):1415-1420.
7. Carey B.J., Eames P.J., Blake M.J., Panerai R.B., Potter J.F. Dynamic cerebral autoregulation is unaffected by aging. Stroke 2000, 31(12):2895-2900.
8. Carey B.J., Panerai R.B., Potter J.F. Effect of aging on dynamic cerebral autoregulation during head-up tilt. Stroke 2003, 34(8):1871-1875.
9. Daal J., Van Lieshout J.J. Falls and medications in the elderly. Neth. J. Med. 2005, 63(3):91-96.
10. Diehl R.R., Linden D., Lucke D., Berlit P. Phase relationship between cerebral blood flow velocity and blood pressure. A clinical test of autoregulation. Stroke 1995, 26(10):1801-1804.
11. Eames P.J., Blake M.J., Panerai R.B., Potter J.F. Cerebral autoregulation indices are unimpaired by hypertension in middle aged and older people. Am. J. Hypertens. 2003, 16(9 (Pt 1)):746-753.
12. Ferrari A.U. Modifications of the cardiovascular system with aging. Am. J. Geriatr. Cardiol. 2002, 11(1):30-33.
13. Gatto R., Hoffman W., Paisansathan C., Mantulin W., Gratton E., Charbel F.T. Effect of age on brain oxygenation regulation during changes in position. J. Neurosci. Methods 2007, 164(2):308-311.
14. Graafmans W.C., Ooms M.E., Hofstee H.M., Bezemer P.D., Bouter L.M., Lips P. Falls in the elderly: a prospective study of risk factors and risk profiles. Am. J. Epidemiol. 1996, 143(11):1129-1136.
15. Harms M.P.M., Colier W.N.J.M., Wieling W., Lenders J.W., Secher N.H., Van Lieshout J.J. Orthostatic tolerance, cerebral oxygenation, and blood velocity in humans with sympathetic failure. Stroke 2000, 31(7):1608-1614.
16. Harms M.P.M., Wesseling K.H., Pott F., Jenstrup M., Van Goudoever J., Secher N.H., Van Lieshout J.J. Continuous stroke volume monitoring by modelling flow from non-invasive measurement of arterial pressure in humans under orthostatic stress. Clin. Sci. (Lond.) 1999, 97(3):291-301.
17. 2. Eur. J. Appl. Physiol. 2006, 96(5):609-614.
18. Immink R.V., van den Born B.J., Van Montfrans G.A., Koopmans R.P., Karemaker J.M., Van Lieshout J.J. Impaired cerebral autoregulation in patients with malignant hypertension. Circulation 2004, 110(15):2241-2245.
19. Immink R.V., Van Montfrans G.A., Stam J., Karemaker J.M., Diamant M., Van Lieshout J.J. Dynamic cerebral autoregulation in acute lacunar and middle cerebral artery territory ischemic stroke. Stroke 2005, 36(12):2595-2600.
20. Jack C.I., Smith T., Neoh C., Lye M., McGalliard J.N. Prevalence of low vision in elderly patients admitted to an acute geriatric unit in Liverpool: elderly people who fall are more likely to have low vision. Gerontology 1995, 41(5):280-285.
21. Lipsitz L.A., Mukai S., Hamner J., Gagnon M., Babikian V. Dynamic regulation of middle cerebral artery blood flow velocity in aging and hypertension. Stroke 2000, 31(8):1897-1903.
22. Lucas R.A., Cotter J.D., Morrison S., Ainslie P.N. The effects of ageing and passive heating on cardiorespiratory and cerebrovascular responses to orthostatic stress in humans. Exp. Physiol. 2008, 93(10):1104-1117.
23. Madsen P.L., Pott F., Olsen S.B., Nielsen H.B., Burcev I., Secher N.H. Near-infrared spectrophotometry determined brain oxygenation during fainting. Acta Physiol. Scand. 1998, 162(4):501-507.
24. Madsen P.L., Secher N.H. Near-infrared oximetry of the brain. Prog. Neurobiol. 1999, 58(6):541-560.
25. Mehagnoul-Schipper D.J., Vloet L.C., Colier W.N.J.M., Hoefnagels W.H.L., Jansen R.W.M.M. Cerebral oxygenation declines in healthy elderly subjects in response to assuming the upright position. Stroke 2000, 31(7):1615-1620.
26. Meyer J.S., Terayama Y., Takashima S. Cerebral circulation in the elderly. Cerebrovasc. Brain Metab. Rev. 1993, 5(2):122-146.
27. Muller M., Bianchi O., Erulku S., Stock C., Schwerdtfeger K. Changes in linear dynamics of cerebrovascular system after severe traumatic brain injury. Stroke 2003, 34(5):1197-1202.
28. Ooi W.L., Hossain M., Lipsitz L.A. The association between orthostatic hypotension and recurrent falls in nursing home residents. Am. J. Med. 2000, 108(2):106-111.
29. Panerai R.B. Cerebral autoregulation: from models to clinical applications. Cardiovasc. Eng. 2008, 8(1):42-59.
30. Panerai R.B., Dawson S.L., Potter J.F. Linear and nonlinear analysis of human dynamic cerebral autoregulation. Am. J. Physiol. Heart Circ. Physiol. 1999, 277(3 (Pt 2)):H1089-H1099.
31. Pott F., Van Lieshout J.J., Ide K., Madsen P., Secher N.H. Middle cerebral artery blood velocity during intense static exercise is dominated by a Valsalva maneuver. J. Appl. Physiol. 2003, 94(4):1335-1344.
32. Rasmussen P., Dawson E.A., Nybo L., Van Lieshout J.J., Secher N.H., Gjedde A. Capillary-oxygenation-level-dependent near-infrared spectrometry in frontal lobe of humans. J. Cereb. Blood Flow Metab. 2007, 27(5):1082-1093.
33. Robbins A.S., Rubenstein L.Z., Josephson K.R., Schulman B.L., Osterweil D., Fine G. Predictors of falls among elderly people. Results of two population-based studies. Arch. Intern. Med. 1989, 149(7):1628-1633.
34. Robinson T.G., James M., Youde J., Panerai R.B., Potter J. Cardiac baroreceptor sensitivity is impaired after acute stroke. Stroke 1997, 28(9):1671-1676.
35. Rogers R.L., Meyer J.S., Mortel K.F., Mahurin R.K., Thornby J. Age-related reductions in cerebral vasomotor reactivity and the law of initial value: a 4-year prospective longitudinal study. J. Cereb. Blood Flow Metab. 1985, 5(1):79-85.
36. Rosner M.J., Coley I.B. Cerebral perfusion pressure, intracranial pressure, and head elevation. J. Neurosurg. 1986, 65(5):636-641.
37. Scheinberg P., Stead E.A. The cerebral blood flow in male subjects as measured by the nitrous oxide technique. Normal values for blood flow, oxygen utilization, glucose utilization and peripheral resistance, with observations on the effect of tilting and anxiety. J. Clin. Invest. 1949, 28(5 (Pt 2)):1163-1171.
38. Schondorf R., Stein R., Roberts R., Benoit J., Cupples W. Dynamic cerebral autoregulation is preserved in neurally mediated syncope. J. Appl. Physiol. 2001, 91(6):2493-2502.
39. Secher N.H., Seifert T., Van Lieshout J.J. Cerebral blood flow and metabolism during exercise, implications for fatigue. J. Appl. Physiol. 2008, 104(1):306-314.
40. Serrador J.M., Hughson R.L., Kowalchuk J.M., Bondar R.L., Gelb A.W. Cerebral blood flow during orthostasis: role of arterial CO2. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2006, 290(4):R1087-R1093.
41. Serrador J.M., Picot P.A., Rutt B.K., Shoemaker J.K., Bondar R.L. MRI measures of middle cerebral artery diameter in conscious humans during simulated orthostasis. Stroke 2000, 31(7):1672-1678.
42. Serrador J.M., Sorond F.A., Vyas M., Gagnon M., Iloputaife I.D., Lipsitz L.A. Cerebral pressure-flow relations in hypertensive elderly humans: transfer gain in different frequency domains. J. Appl. Physiol. 2005, 98(1):151-159.
43. Shaw T.G., Mortel K.F., Meyer J.S., Rogers R.L., Hardenberg J., Cutaia M.M. Cerebral blood flow changes in benign aging and cerebrovascular disease. Neurology 1984, 34(7):855-862.
44. Sorond F.A., Khavari R., Serrador J.M., Lipsitz L.A. Regional cerebral autoregulation during orthostatic stress: age-related differences. J. Gerontol. A Biol. Sci. Med. Sci. 2005, 60(11):1484-1487.
45. Sprangers R.L.H., Van Lieshout J.J., Karemaker J.M., Wesseling K.H., Wieling W. Circulatory responses to stand up: discrimination between the effects of respiration, orthostasis and exercise. Clin. Physiol. 1991, 11(3):221-230.
46. Tinetti M.E., Speechley M., Ginter S.F. Risk factors for falls among elderly persons living in the community. N. Engl. J. Med. 1988, 319(26):1701-1707.
47. Tsutsui Y., Sagawa S., Yamauchi K., Endo Y., Yamazaki F., Shiraki K. Cardiovascular responses to lower body negative pressure in the elderly: role of reduced leg compliance. Gerontology 2002, 48(3):133-139.
48. Van Dijk N., de Bruin I.G., Gisolf J., Bruin-Bon H.A., Linzer M., Van Lieshout J.J., Wieling W. Hemodynamic effects of legcrossing and skeletal muscle tensing during free standing in patients with vasovagal syncope. J. Appl. Physiol. 2005, 98(2):584-590.
49. Van Lieshout J.J., Pott F., Madsen P.L., Van Goudoever J., Secher N.H. Muscle tensing during standing: effects on cerebral tissue oxygenation and cerebral artery blood velocity. Stroke 2001, 32(7):1546-1551.
50. Van Lieshout J.J., Wieling W., Karemaker J.M., Secher N.H. Syncope, cerebral perfusion, and oxygenation. J. Appl. Physiol. 2003, 94(3):833-848.
51. Wieling W., Krediet C.T., Van Dijk N., Linzer M., Tschakovsky M.E. Initial orthostatic hypotension: review of a forgotten condition. Clin. Sci. (Lond.) 2007, 112(3):157-165.
52. Wieling W., Ten Harkel A.D.J., Van Lieshout J.J. Spectrum of orthostatic disorders: classification based on an analysis of the short-term circulatory response upon standing. Clin. Sci. (Lond.) 1991, 81(2):241-248.