-
1
-
-
33845944601
-
Arsenicderivatives in hematologic malignancies: A role beyond acute promyelocyticleukemia?
-
Verstovsek, S.; Giles, F.; Quintas-Cardama, A.; Perez, N.; Ravandi-Kashani, F.; Beran, M.; Freireich, E.; Kantarjian, H. Arsenicderivatives in hematologic malignancies: a role beyond acute promyelocyticleukemia? Hematol. Oncol., 2006, 24(4), 181-188.
-
(2006)
Hematol. Oncol.
, vol.24
, Issue.4
, pp. 181-188
-
-
Verstovsek, S.1
Giles, F.2
Quintas-Cardama, A.3
Perez, N.4
Ravandi-Kashani, F.5
Beran, M.6
Freireich, E.7
Kantarjian, H.8
-
2
-
-
0035038845
-
History of the development of arsenicderivatives in cancer therapy
-
Waxman, S.; Anderson, K.C. History of the development of arsenicderivatives in cancer therapy. Oncologist, 2001, 6(Suppl 2), 3-10.
-
(2001)
Oncologist
, vol.6
, Issue.SUPPL. 2
, pp. 3-10
-
-
Waxman, S.1
Anderson, K.C.2
-
3
-
-
0035031195
-
Introduction: The history of arsenic trioxide in cancertherapy
-
Antman, K.H. Introduction: the history of arsenic trioxide in cancertherapy. Oncologist, 2001, 6(Suppl 2), 1-2.
-
(2001)
Oncologist
, vol.6
, Issue.SUPPL. 2
, pp. 1-2
-
-
Antman, K.H.1
-
4
-
-
0030610687
-
Use of arsenic trioxide (As2O3) in thetreatment of acute promyelocytic leukemia (APL): II. Clinical efficacyand pharmacokinetics in relapsed patients
-
Shen, Z.X.; Chen, G.Q.; Ni, J.H.; Li, X.S.; Xiong, S.M.; Qiu, Q.Y.; Zhu, J.; Tang, W.; Sun, G.L.; Yang, K.Q.; Chen, Y.; Zhou, L.; Fang, Z.W.; Wang, Y.T.; Ma, J.; Zhang, P.; Zhang, T.D.; Chen, S.J.; Chen, Z.; Wang, Z.Y. Use of arsenic trioxide (As2O3) in thetreatment of acute promyelocytic leukemia (APL): II. Clinical efficacyand pharmacokinetics in relapsed patients. Blood, 1997, 89(9), 3354-3360.
-
(1997)
Blood
, vol.89
, Issue.9
, pp. 3354-3360
-
-
Shen, Z.X.1
Chen, G.Q.2
Ni, J.H.3
Li, X.S.4
Xiong, S.M.5
Qiu, Q.Y.6
Zhu, J.7
Tang, W.8
Sun, G.L.9
Yang, K.Q.10
Chen, Y.11
Zhou, L.12
Fang, Z.W.13
Wang, Y.T.14
Ma, J.15
Zhang, P.16
Zhang, T.D.17
Chen, S.J.18
Chen, Z.19
Wang, Z.Y.20
more..
-
5
-
-
0032487923
-
Complete remission aftertreatment of acute promyelocytic leukemia with arsenic trioxide
-
Soignet, S.L.; Maslak, P.; Wang, Z.G.; Jhanwar, S.; Calleja, E.; Dardashti, L.J.; Corso, D.; DeBlasio, A.; Gabrilove, J.; Scheinberg, D.A.; Pandolfi, P.P.; Warrell, R.P., Jr. Complete remission aftertreatment of acute promyelocytic leukemia with arsenic trioxide. N.Engl. J. Med., 1998, 339(19), 1341-1348.
-
(1998)
N.Engl. J. Med.
, vol.339
, Issue.19
, pp. 1341-1348
-
-
Soignet, S.L.1
Maslak, P.2
Wang, Z.G.3
Jhanwar, S.4
Calleja, E.5
Dardashti, L.J.6
Corso, D.7
DeBlasio, A.8
Gabrilove, J.9
Scheinberg, D.A.10
Pandolfi, P.P.11
Warrell Jr., R.P.12
-
6
-
-
11144355810
-
All-trans retinoic acid/As2O3 combination yields a high qualityremission and survival in newly diagnosed acute promyelocyticleukemia
-
Shen, Z.X.; Shi, Z.Z.; Fang, J.; Gu, B.W.; Li, J.M.; Zhu, Y.M.; Shi, J.Y.; Zheng, P.Z.; Yan, H.; Liu, Y.F.; Chen, Y.; Shen, Y.; Wu, W.; Tang, W.; Waxman, S.; De The, H.; Wang, Z.Y.; Chen, S.J.; Chen, Z. All-trans retinoic acid/As2O3 combination yields a high qualityremission and survival in newly diagnosed acute promyelocyticleukemia. Proc. Natl. Acad. Sci. USA, 2004, 101(15), 5328-5335.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, Issue.15
, pp. 5328-5335
-
-
Shen, Z.X.1
Shi, Z.Z.2
Fang, J.3
Gu, B.W.4
Li, J.M.5
Zhu, Y.M.6
Shi, J.Y.7
Zheng, P.Z.8
Yan, H.9
Liu, Y.F.10
Chen, Y.11
Shen, Y.12
Wu, W.13
Tang, W.14
Waxman, S.15
De The, H.16
Wang, Z.Y.17
Chen, S.J.18
Chen, Z.19
-
7
-
-
6944247414
-
An efficient therapeutic approachto patients with acute promyelocytic leukemia using a combinationof arsenic trioxide with low-dose all-trans retinoic acid
-
Wang, G.; Li, W.; Cui, J.; Gao, S.; Yao, C.; Jiang, Z.; Song, Y.; Yuan, C.J.; Yang, Y.; Liu, Z.; Cai, L. An efficient therapeutic approachto patients with acute promyelocytic leukemia using a combinationof arsenic trioxide with low-dose all-trans retinoic acid.Hematol. Oncol., 2004, 22(2), 63-71.
-
(2004)
Hematol. Oncol.
, vol.22
, Issue.2
, pp. 63-71
-
-
Wang, G.1
Li, W.2
Cui, J.3
Gao, S.4
Yao, C.5
Jiang, Z.6
Song, Y.7
Yuan, C.J.8
Yang, Y.9
Liu, Z.10
Cai, L.11
-
8
-
-
0345713156
-
Acute myeloid leukemia
-
Lowenberg, B.; Downing, J.R.; Burnett, A. Acute myeloid leukemia.N. Engl. J. Med., 1999, 341(14), 1051-1062.
-
(1999)
N. Engl. J. Med.
, vol.341
, Issue.14
, pp. 1051-1062
-
-
Lowenberg, B.1
Downing, J.R.2
Burnett, A.3
-
9
-
-
17144377127
-
Arsenic trioxide: New clinical experiencewith an old medication in hematologic malignancies
-
Douer, D.; Tallman, M.S. Arsenic trioxide: new clinical experiencewith an old medication in hematologic malignancies. J. Clin.Oncol., 2005, 23(10), 2396-2410.
-
(2005)
J. Clin.Oncol.
, vol.23
, Issue.10
, pp. 2396-2410
-
-
Douer, D.1
Tallman, M.S.2
-
10
-
-
0035884639
-
United States multicenter study of arsenic trioxide inrelapsed acute promyelocytic leukemia
-
Soignet, S.L.; Frankel, S.R.; Douer, D.; Tallman, M.S.; Kantarjian, H.; Calleja, E.; Stone, R.M.; Kalaycio, M.; Scheinberg, D.A.; Steinherz, P.; Sievers, E.L.; Coutre, S.; Dahlberg, S.; Ellison, R.; Warrell, R.P., Jr. United States multicenter study of arsenic trioxide inrelapsed acute promyelocytic leukemia. J. Clin. Oncol., 2001, 19(18), 3852-3860.
-
(2001)
J. Clin. Oncol.
, vol.19
, Issue.18
, pp. 3852-3860
-
-
Soignet, S.L.1
Frankel, S.R.2
Douer, D.3
Tallman, M.S.4
Kantarjian, H.5
Calleja, E.6
Stone, R.M.7
Kalaycio, M.8
Scheinberg, D.A.9
Steinherz, P.10
Sievers, E.L.11
Coutre, S.12
Dahlberg, S.13
Ellison, R.14
Warrell Jr., R.P.15
-
11
-
-
77956251955
-
Single-agentarsenic trioxide in the treatment of newly diagnosed acute promyelocyticleukemia: Long-term follow-up data
-
Mathews, V.; George, B.; Chendamarai, E.; Lakshmi, K.M.; Desire, S.; Balasubramanian, P.; Viswabandya, A.; Thirugnanam, R.; Abraham, A.; Shaji, R.V.; Srivastava, A.; Chandy, M. Single-agentarsenic trioxide in the treatment of newly diagnosed acute promyelocyticleukemia: long-term follow-up data. J. Clin. Oncol., 2010, 28(24), 3866-3871.
-
(2010)
J. Clin. Oncol.
, vol.28
, Issue.24
, pp. 3866-3871
-
-
Mathews, V.1
George, B.2
Chendamarai, E.3
Lakshmi, K.M.4
Desire, S.5
Balasubramanian, P.6
Viswabandya, A.7
Thirugnanam, R.8
Abraham, A.9
Shaji, R.V.10
Srivastava, A.11
Chandy, M.12
-
12
-
-
0030890942
-
Arsenic-induced PML targetingonto nuclear bodies: Implications for the treatment of acute promyelocyticleukemia
-
Zhu, J.; Koken, M.H.; Quignon, F.; Chelbi-Alix, M.K.; Degos, L.; Wang, Z.Y.; Chen, Z.; de The, H. Arsenic-induced PML targetingonto nuclear bodies: implications for the treatment of acute promyelocyticleukemia. Proc. Natl. Acad. Sci. USA, 1997, 94(8), 3978-3983.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, Issue.8
, pp. 3978-3983
-
-
Zhu, J.1
Koken, M.H.2
Quignon, F.3
Chelbi-Alix, M.K.4
Degos, L.5
Wang, Z.Y.6
Chen, Z.7
de The, H.8
-
13
-
-
0000531696
-
Arsenic trioxide as an inducer of apoptosisand loss of PML/RAR alpha protein in acute promyelocyticleukemia cells
-
Shao, W.; Fanelli, M.; Ferrara, F.F.; Riccioni, R.; Rosenauer, A.; Davison, K.; Lamph, W.W.; Waxman, S.; Pelicci, P.G.; Lo Coco, F.; Avvisati, G.; Testa, U.; Peschle, C.; Gambacorti-Passerini, C.; Nervi, C.; Miller, W.H., Jr. Arsenic trioxide as an inducer of apoptosisand loss of PML/RAR alpha protein in acute promyelocyticleukemia cells. J. Natl. Cancer Inst., 1998, 90(2), 124-133.
-
(1998)
J. Natl. Cancer Inst.
, vol.90
, Issue.2
, pp. 124-133
-
-
Shao, W.1
Fanelli, M.2
Ferrara, F.F.3
Riccioni, R.4
Rosenauer, A.5
Davison, K.6
Lamph, W.W.7
Waxman, S.8
Pelicci, P.G.9
Lo Coco, F.10
Avvisati, G.11
Testa, U.12
Peschle, C.13
Gambacorti-Passerini, C.14
Nervi, C.15
Miller Jr., W.H.16
-
14
-
-
0033526358
-
Apoptosis and growth inhibition in malignant lymphocytes after treatment with arsenictrioxide at clinically achievable concentrations
-
Zhu, X.H.; Shen, Y.L.; Jing, Y.K.; Cai, X.; Jia, P.M.; Huang, Y.; Tang, W.; Shi, G.Y.; Sun, Y.P.; Dai, J.; Wang, Z.Y.; Chen, S.J.; Zhang, T.D.; Waxman, S.; Chen, Z.; Chen, G.Q. Apoptosis and growth inhibition in malignant lymphocytes after treatment with arsenictrioxide at clinically achievable concentrations. J. Natl.Cancer Inst., 1999, 91(9), 772-778.
-
(1999)
J. Natl.Cancer Inst.
, vol.91
, Issue.9
, pp. 772-778
-
-
Zhu, X.H.1
Shen, Y.L.2
Jing, Y.K.3
Cai, X.4
Jia, P.M.5
Huang, Y.6
Tang, W.7
Shi, G.Y.8
Sun, Y.P.9
Dai, J.10
Wang, Z.Y.11
Chen, S.J.12
Zhang, T.D.13
Waxman, S.14
Chen, Z.15
Chen, G.Q.16
-
15
-
-
0033105268
-
Arsenic trioxide and melarsoprolinduce apoptosis in plasma cell lines and in plasma cells from myelomapatients
-
Rousselot, P.; Labaume, S.; Marolleau, J.P.; Larghero, J.; Noguera, M.H.; Brouet, J.C.; Fermand, J.P. Arsenic trioxide and melarsoprolinduce apoptosis in plasma cell lines and in plasma cells from myelomapatients. Cancer Res., 1999, 59(5), 1041-1048.
-
(1999)
Cancer Res.
, vol.59
, Issue.5
, pp. 1041-1048
-
-
Rousselot, P.1
Labaume, S.2
Marolleau, J.P.3
Larghero, J.4
Noguera, M.H.5
Brouet, J.C.6
Fermand, J.P.7
-
16
-
-
0036739745
-
Clinical activity of arsenic trioxide for the treatment of multiple myeloma
-
Munshi, N.C.; Tricot, G.; Desikan, R.; Badros, A.; Zangari, M.; Toor, A.; Morris, C.; Anaissie, E.; Barlogie, B. Clinical activity of arsenic trioxide for the treatment of multiple myeloma. Leukemia, 2002, 16(9), 1835-1837.
-
(2002)
Leukemia
, vol.16
, Issue.9
, pp. 1835-1837
-
-
Munshi, N.C.1
Tricot, G.2
Desikan, R.3
Badros, A.4
Zangari, M.5
Toor, A.6
Morris, C.7
Anaissie, E.8
Barlogie, B.9
-
17
-
-
4444275232
-
A clinical and pharmacological study of arsenic trioxide in advanced multiplemyeloma patients
-
Rousselot, P.; Larghero, J.; Arnulf, B.; Poupon, J.; Royer, B.; Tibi, A.; Madelaine-Chambrin, I.; Cimerman, P.; Chevret, S.; Hermine, O.; Dombret, H.; Claude Brouet, J.; Paul Fermand, J. A clinical and pharmacological study of arsenic trioxide in advanced multiplemyeloma patients. Leukemia, 2004, 18(9), 1518-1521.
-
(2004)
Leukemia
, vol.18
, Issue.9
, pp. 1518-1521
-
-
Rousselot, P.1
Larghero, J.2
Arnulf, B.3
Poupon, J.4
Royer, B.5
Tibi, A.6
Madelaine-Chambrin, I.7
Cimerman, P.8
Chevret, S.9
Hermine, O.10
Dombret, H.11
Claude Brouet, J.12
Paul Fermand, J.13
-
18
-
-
4444221348
-
Arsenic trioxide: Expanding roles for an ancient drug?
-
Ravandi, F. Arsenic trioxide: expanding roles for an ancient drug?Leukemia, 2004, 18(9), 1457-1459.
-
(2004)
Leukemia
, vol.18
, Issue.9
, pp. 1457-1459
-
-
Ravandi, F.1
-
19
-
-
0042528608
-
Opportunities for Trisenox (arsenic trioxide) inthe treatment of myelodysplastic syndromes
-
List, A.; Beran, M.; DiPersio, J.; Slack, J.; Vey, N.; Rosenfeld, C.S.; Greenberg, P. Opportunities for Trisenox (arsenic trioxide) inthe treatment of myelodysplastic syndromes. Leukemia, 2003, 17(8), 1499-1507.
-
(2003)
Leukemia
, vol.17
, Issue.8
, pp. 1499-1507
-
-
List, A.1
Beran, M.2
DiPersio, J.3
Slack, J.4
Vey, N.5
Rosenfeld, C.S.6
Greenberg, P.7
-
20
-
-
33744966168
-
Arsenic trioxide in patients withmyelodysplastic syndromes: A phase II multicenter study
-
Vey, N.; Bosly, A.; Guerci, A.; Feremans, W.; Dombret, H.; Dreyfus, F.; Bowen, D.; Burnett, A.; Dennis, M.; Ribrag, V.; Casadevall, N.; Legros, L.; Fenaux, P. Arsenic trioxide in patients withmyelodysplastic syndromes: a phase II multicenter study. J. Clin.Oncol., 2006, 24(16), 2465-2471.
-
(2006)
J. Clin.Oncol.
, vol.24
, Issue.16
, pp. 2465-2471
-
-
Vey, N.1
Bosly, A.2
Guerci, A.3
Feremans, W.4
Dombret, H.5
Dreyfus, F.6
Bowen, D.7
Burnett, A.8
Dennis, M.9
Ribrag, V.10
Casadevall, N.11
Legros, L.12
Fenaux, P.13
-
21
-
-
33745002275
-
Phase II multicenter study of arsenictrioxide in patients with myelodysplastic syndromes
-
Schiller, G.J.; Slack, J.; Hainsworth, J.D.; Mason, J.; Saleh, M.; Rizzieri, D.; Douer, D.; List, A.F. Phase II multicenter study of arsenictrioxide in patients with myelodysplastic syndromes. J. Clin.Oncol., 2006, 24(16), 2456-2464.
-
(2006)
J. Clin.Oncol.
, vol.24
, Issue.16
, pp. 2456-2464
-
-
Schiller, G.J.1
Slack, J.2
Hainsworth, J.D.3
Mason, J.4
Saleh, M.5
Rizzieri, D.6
Douer, D.7
List, A.F.8
-
22
-
-
33745009313
-
Is intravenous arsenic trioxide a useful therapy inmyelodysplastic syndromes?
-
Stone, R.M. Is intravenous arsenic trioxide a useful therapy inmyelodysplastic syndromes? J. Clin. Oncol., 2006, 24(16), 2414-2416.
-
(2006)
J. Clin. Oncol.
, vol.24
, Issue.16
, pp. 2414-2416
-
-
Stone, R.M.1
-
23
-
-
3242689062
-
Phase II trial of arsenic trioxidein relapsed and refractory acute myeloid leukemia, secondaryleukemia and/or newly diagnosed patients at least 65 years old
-
Parmar, S.; Rundhaugen, L.M.; Boehlke, L.; Riley, M.; Nabhan, C.; Raji, A.; Frater, J.L.; Tallman, M.S. Phase II trial of arsenic trioxidein relapsed and refractory acute myeloid leukemia, secondaryleukemia and/or newly diagnosed patients at least 65 years old.Leuk. Res., 2004, 28(9), 909-919.
-
(2004)
Leuk. Res.
, vol.28
, Issue.9
, pp. 909-919
-
-
Parmar, S.1
Rundhaugen, L.M.2
Boehlke, L.3
Riley, M.4
Nabhan, C.5
Raji, A.6
Frater, J.L.7
Tallman, M.S.8
-
24
-
-
0141502208
-
Downmodulation of ERK activity inhibitsthe proliferation and induces the apoptosis of primary acutemyelogenous leukemia blasts
-
Lunghi, P.; Tabilio, A.; Dall'Aglio, P.P.; Ridolo, E.; Carlo-Stella, C.; Pelicci, P.G.; Bonati, A. Downmodulation of ERK activity inhibitsthe proliferation and induces the apoptosis of primary acutemyelogenous leukemia blasts. Leukemia, 2003, 17(9), 1783-1793.
-
(2003)
Leukemia
, vol.17
, Issue.9
, pp. 1783-1793
-
-
Lunghi, P.1
Tabilio, A.2
Dall'Aglio, P.P.3
Ridolo, E.4
Carlo-Stella, C.5
Pelicci, P.G.6
Bonati, A.7
-
25
-
-
33744496269
-
MEK1 inhibitionsensitizes primary acute myelogenous leukemia to arsenic trioxideinducedapoptosis
-
Lunghi, P.; Costanzo, A.; Salvatore, L.; Noguera, N.; Mazzera, L.; Tabilio, A.; Lo-Coco, F.; Levrero, M.; Bonati, A. MEK1 inhibitionsensitizes primary acute myelogenous leukemia to arsenic trioxideinducedapoptosis. Blood, 2006, 107(11), 4549-53.
-
(2006)
Blood
, vol.107
, Issue.11
, pp. 4549-4553
-
-
Lunghi, P.1
Costanzo, A.2
Salvatore, L.3
Noguera, N.4
Mazzera, L.5
Tabilio, A.6
Lo-Coco, F.7
Levrero, M.8
Bonati, A.9
-
26
-
-
33750314586
-
Synergistic effect of arsenictrioxide and flt3 inhibition on cells with flt3 internal tandem duplication
-
Takahashi, S.; Harigae, H.; Yokoyama, H.; Ishikawa, I.; Abe, S.; Imaizumi, M.; Sasaki, T.; Kaku, M. Synergistic effect of arsenictrioxide and flt3 inhibition on cells with flt3 internal tandem duplication.Int. J. Hematol., 2006, 84(3), 256-261.
-
(2006)
Int. J. Hematol.
, vol.84
, Issue.3
, pp. 256-261
-
-
Takahashi, S.1
Harigae, H.2
Yokoyama, H.3
Ishikawa, I.4
Abe, S.5
Imaizumi, M.6
Sasaki, T.7
Kaku, M.8
-
27
-
-
33744457653
-
Phosphoinositide 3-kinase/Akt signalingpathway and its therapeutical implications for human acutemyeloid leukemia
-
Martelli, A.M.; Nyakern, M.; Tabellini, G.; Bortul, R.; Tazzari, P.L.; Evangelisti, C.; Cocco, L. Phosphoinositide 3-kinase/Akt signalingpathway and its therapeutical implications for human acutemyeloid leukemia. Leukemia, 2006, 20(6), 911-928.
-
(2006)
Leukemia
, vol.20
, Issue.6
, pp. 911-928
-
-
Martelli, A.M.1
Nyakern, M.2
Tabellini, G.3
Bortul, R.4
Tazzari, P.L.5
Evangelisti, C.6
Cocco, L.7
-
28
-
-
18544374589
-
Pharmacologic inhibitors of PI3K/Akt potentiate the apoptoticaction of the antileukemic drug arsenic trioxide via glutathionedepletion and increased peroxide accumulation in myeloidleukemia cells
-
Ramos, A.M.; Fernandez, C.; Amran, D.; Sancho, P.; de Blas, E.; Aller, P. Pharmacologic inhibitors of PI3K/Akt potentiate the apoptoticaction of the antileukemic drug arsenic trioxide via glutathionedepletion and increased peroxide accumulation in myeloidleukemia cells. Blood, 2005, 105(10), 4013-4020.
-
(2005)
Blood
, vol.105
, Issue.10
, pp. 4013-4020
-
-
Ramos, A.M.1
Fernandez, C.2
Amran, D.3
Sancho, P.4
de Blas, E.5
Aller, P.6
-
29
-
-
32544435965
-
TRAIL sensitisation by arsenic trioxide is caspase-8 dependent and involves modulation of death receptor components and Akt
-
Szegezdi, E.; Cahill, S.; Meyer, M.; O'Dwyer, M.; Samali, A.TRAIL sensitisation by arsenic trioxide is caspase-8 dependent and involves modulation of death receptor components and Akt. Br. J.Cancer, 2006, 94(3), 398-406.
-
(2006)
Br. J.Cancer
, vol.94
, Issue.3
, pp. 398-406
-
-
Szegezdi, E.1
Cahill, S.2
Meyer, M.3
O'Dwyer, M.4
Samali, A.5
-
30
-
-
0032933610
-
Malignant cells canbe sensitized to undergo growth inhibition and apoptosis by arsenictrioxide through modulation of the glutathione redox system
-
Dai, J.; Weinberg, R.S.; Waxman, S.; Jing, Y. Malignant cells canbe sensitized to undergo growth inhibition and apoptosis by arsenictrioxide through modulation of the glutathione redox system.Blood, 1999, 93(1), 268-277.
-
(1999)
Blood
, vol.93
, Issue.1
, pp. 268-277
-
-
Dai, J.1
Weinberg, R.S.2
Waxman, S.3
Jing, Y.4
-
31
-
-
0037160016
-
Activation of Rac1 and the p38 mitogen-activated protein kinasepathway in response to arsenic trioxide
-
Verma, A.; Mohindru, M.; Deb, D.K.; Sassano, A.; Kambhampati, S.; Ravandi, F.; Minucci, S.; Kalvakolanu, D.V.; Platanias, L.C.Activation of Rac1 and the p38 mitogen-activated protein kinasepathway in response to arsenic trioxide. J. Biol. Chem., 2002, 277(47), 44988-44995.
-
(2002)
J. Biol. Chem.
, vol.277
, Issue.47
, pp. 44988-44995
-
-
Verma, A.1
Mohindru, M.2
Deb, D.K.3
Sassano, A.4
Kambhampati, S.5
Ravandi, F.6
Minucci, S.7
Kalvakolanu, D.V.8
Platanias, L.C.9
-
32
-
-
0042885973
-
The Hsp90chaperone complex as a novel target for cancer therapy
-
Goetz, M.P.; Toft, D.O.; Ames, M.M.; Erlichman, C. The Hsp90chaperone complex as a novel target for cancer therapy. Ann.Oncol., 2003, 14(8), 1169-1176.
-
(2003)
Ann.Oncol.
, vol.14
, Issue.8
, pp. 1169-1176
-
-
Goetz, M.P.1
Toft, D.O.2
Ames, M.M.3
Erlichman, C.4
-
33
-
-
77951680995
-
Heat shock protein 90 inhibitors attenuate inflammatoryresponses in atherosclerosis
-
Madrigal-Matute, J.; Lopez-Franco, O.; Blanco-Colio, L.M.; Munoz-Garcia, B.; Ramos-Mozo, P.; Ortega, L.; Egido, J.; Martin-Ventura, J.L. Heat shock protein 90 inhibitors attenuate inflammatoryresponses in atherosclerosis. Cardiovasc. Res., 2010, 86(2), 330-337.
-
(2010)
Cardiovasc. Res.
, vol.86
, Issue.2
, pp. 330-337
-
-
Madrigal-Matute, J.1
Lopez-Franco, O.2
Blanco-Colio, L.M.3
Munoz-Garcia, B.4
Ramos-Mozo, P.5
Ortega, L.6
Egido, J.7
Martin-Ventura, J.L.8
-
34
-
-
33646488373
-
Targeting Hsp90 by 17-AAG in leukemiacells: Mechanisms for synergistic and antagonistic drugcombinations with arsenic trioxide and Ara-C
-
Pelicano, H.; Carew, J.S.; McQueen, T.J.; Andreeff, M.; Plunkett, W.; Keating, M.J.; Huang, P. Targeting Hsp90 by 17-AAG in leukemiacells: mechanisms for synergistic and antagonistic drugcombinations with arsenic trioxide and Ara-C. Leukemia, 2006, 20(4), 610-619.
-
(2006)
Leukemia
, vol.20
, Issue.4
, pp. 610-619
-
-
Pelicano, H.1
Carew, J.S.2
McQueen, T.J.3
Andreeff, M.4
Plunkett, W.5
Keating, M.J.6
Huang, P.7
-
35
-
-
0035886024
-
Nuclear factorkappaBis constitutively activated in primitive human acute myelogenousleukemia cells
-
Guzman, M.L.; Neering, S.J.; Upchurch, D.; Grimes, B.; Howard, D.S.; Rizzieri, D.A.; Luger, S.M.; Jordan, C.T. Nuclear factorkappaBis constitutively activated in primitive human acute myelogenousleukemia cells. Blood, 2001, 98(8), 2301-2307.
-
(2001)
Blood
, vol.98
, Issue.8
, pp. 2301-2307
-
-
Guzman, M.L.1
Neering, S.J.2
Upchurch, D.3
Grimes, B.4
Howard, D.S.5
Rizzieri, D.A.6
Luger, S.M.7
Jordan, C.T.8
-
36
-
-
77952775055
-
Synergistic antiproliferative effect of arsenic trioxidecombined with bortezomib in HL60 cell line and primary blastsfrom patients affected by myeloproliferative disorders
-
Canestraro, M.; Galimberti, S.; Savli, H.; Palumbo, G.A.; Tibullo, D.; Nagy, B.; Guerrini, F.; Piaggi, S.; Cine, N.; Metelli, M.R.; Petrini, M. Synergistic antiproliferative effect of arsenic trioxidecombined with bortezomib in HL60 cell line and primary blastsfrom patients affected by myeloproliferative disorders. CancerGenet. Cytogenet., 2010, 199(2), 110-120.
-
(2010)
CancerGenet. Cytogenet.
, vol.199
, Issue.2
, pp. 110-120
-
-
Canestraro, M.1
Galimberti, S.2
Savli, H.3
Palumbo, G.A.4
Tibullo, D.5
Nagy, B.6
Guerrini, F.7
Piaggi, S.8
Cine, N.9
Metelli, M.R.10
Petrini, M.11
-
37
-
-
34250744640
-
Arsenic trioxide and proteasome inhibitor bortezomib synergisticallyinduce apoptosis in leukemic cells: The role of proteinkinase Cdelta
-
Yan, H.; Wang, Y.C.; Li, D.; Wang, Y.; Liu, W.; Wu, Y.L.; Chen, G.Q. Arsenic trioxide and proteasome inhibitor bortezomib synergisticallyinduce apoptosis in leukemic cells: the role of proteinkinase Cdelta. Leukemia, 2007, 21(7), 1488-1495.
-
(2007)
Leukemia
, vol.21
, Issue.7
, pp. 1488-1495
-
-
Yan, H.1
Wang, Y.C.2
Li, D.3
Wang, Y.4
Liu, W.5
Wu, Y.L.6
Chen, G.Q.7
-
38
-
-
34548850030
-
Low-dose arsenic trioxide sensitizes glucocorticoid-resistantacute lymphoblastic leukemia cells to dexamethasone via an Aktdependentpathway
-
Bornhauser, B.C.; Bonapace, L.; Lindholm, D.; Martinez, R.; Cario, G.; Schrappe, M.; Niggli, F.K.; Schafer, B.W.; Bourquin, J.P. Low-dose arsenic trioxide sensitizes glucocorticoid-resistantacute lymphoblastic leukemia cells to dexamethasone via an Aktdependentpathway. Blood, 2007, 110(6), 2084-2091.
-
(2007)
Blood
, vol.110
, Issue.6
, pp. 2084-2091
-
-
Bornhauser, B.C.1
Bonapace, L.2
Lindholm, D.3
Martinez, R.4
Cario, G.5
Schrappe, M.6
Niggli, F.K.7
Schafer, B.W.8
Bourquin, J.P.9
-
39
-
-
85036721299
-
Inductionof B-chronic lymphocytic leukemia cell apoptosis by arsenictrioxide involves suppression of the PI3K/Akt pathway via JNK activation and PTEN upregulation
-
Jun 9 [Epub ahead of print]
-
Redondo-Munoz, J.; Escobar-Diaz, E.; Hernandez Del Cerro, M.; Padiella, A.; Terol, M.J.; Garcia-Marco, J.A.; Garcia-Pardo, A. Inductionof B-chronic lymphocytic leukemia cell apoptosis by arsenictrioxide involves suppression of the PI3K/Akt pathway via JNK activation and PTEN upregulation. Clin. Cancer Res., 2010 Jun 9 [Epub ahead of print]
-
(2010)
Clin. Cancer Res.
-
-
Redondo-Munoz, J.1
Escobar-Diaz, E.2
Hernandez Del Cerro, M.3
Padiella, A.4
Terol, M.J.5
Garcia-Marco, J.A.6
Garcia-Pardo, A.7
-
40
-
-
0031708772
-
The induction of apoptosis and cell cycle arrest by arsenic trioxide in lymphoid neoplasms
-
Zhang, W.; Ohnishi, K.; Shigeno, K.; Fujisawa, S.; Naito, K.; Nakamura, S.; Takeshita, K.; Takeshita, A.; Ohno, R. The induction of apoptosis and cell cycle arrest by arsenic trioxide in lymphoid neoplasms.Leukemia, 1998, 12(9), 1383-1391.
-
(1998)
Leukemia
, vol.12
, Issue.9
, pp. 1383-1391
-
-
Zhang, W.1
Ohnishi, K.2
Shigeno, K.3
Fujisawa, S.4
Naito, K.5
Nakamura, S.6
Takeshita, K.7
Takeshita, A.8
Ohno, R.9
-
41
-
-
77249144468
-
Arsenic-trioxide-inducedapoptosis of chronic lymphocytic leukemia cells
-
Bairey, O.; Vanichkin, A.; Shpilberg, O. Arsenic-trioxide-inducedapoptosis of chronic lymphocytic leukemia cells. Int. J. Lab Hematol., 2010, 32(1 Pt 1), e77-85.
-
(2010)
Int. J. Lab Hematol.
, vol.32
, Issue.1 PART 1
-
-
Bairey, O.1
Vanichkin, A.2
Shpilberg, O.3
-
42
-
-
0037926836
-
Free radical stress in chronic lymphocytic leukemia cells and itsrole in cellular sensitivity to ROS-generating anticancer agents
-
Zhou, Y.; Hileman, E.O.; Plunkett, W.; Keating, M.J.; Huang, P. Free radical stress in chronic lymphocytic leukemia cells and itsrole in cellular sensitivity to ROS-generating anticancer agents.Blood, 2003, 101(10), 4098-4104.
-
(2003)
Blood
, vol.101
, Issue.10
, pp. 4098-4104
-
-
Zhou, Y.1
Hileman, E.O.2
Plunkett, W.3
Keating, M.J.4
Huang, P.5
-
43
-
-
77952952716
-
Arsenic trioxide and ascorbic aciddemonstrate promising activity against primary human CLL cells invitro
-
Biswas, S.; Zhao, X.; Mone, A.P.; Mo, X.; Vargo, M.; Jarjoura, D.; Byrd, J.C.; Muthusamy, N. Arsenic trioxide and ascorbic aciddemonstrate promising activity against primary human CLL cells invitro. Leuk. Res., 2010, 34(7), 925-931.
-
(2010)
Leuk. Res.
, vol.34
, Issue.7
, pp. 925-931
-
-
Biswas, S.1
Zhao, X.2
Mone, A.P.3
Mo, X.4
Vargo, M.5
Jarjoura, D.6
Byrd, J.C.7
Muthusamy, N.8
-
44
-
-
0034212785
-
Arsenic trioxide-mediated growth inhibitionin MC/CAR myeloma cells via cell cycle arrest in associationwith induction of cyclin-dependent kinase inhibitor, p21, and apoptosis
-
Park, W.H.; Seol, J.G.; Kim, E.S.; Hyun, J.M.; Jung, C.W.; Lee, C.C.; Kim, B.K.; Lee, Y.Y. Arsenic trioxide-mediated growth inhibitionin MC/CAR myeloma cells via cell cycle arrest in associationwith induction of cyclin-dependent kinase inhibitor, p21, and apoptosis. Cancer Res., 2000, 60(11), 3065-3071.
-
(2000)
Cancer Res.
, vol.60
, Issue.11
, pp. 3065-3071
-
-
Park, W.H.1
Seol, J.G.2
Kim, E.S.3
Hyun, J.M.4
Jung, C.W.5
Lee, C.C.6
Kim, B.K.7
Lee, Y.Y.8
-
45
-
-
0037772194
-
Arsenic trioxide-induced apoptosisin myeloma cells: P53-dependent G1 or G2/M cell cycle arrest, activation of caspase-8 or caspase-9, and synergy withAPO2/TRAIL
-
Liu, Q.; Hilsenbeck, S.; Gazitt, Y. Arsenic trioxide-induced apoptosisin myeloma cells: p53-dependent G1 or G2/M cell cycle arrest, activation of caspase-8 or caspase-9, and synergy withAPO2/TRAIL. Blood, 2003, 101(10), 4078-4087.
-
(2003)
Blood
, vol.101
, Issue.10
, pp. 4078-4087
-
-
Liu, Q.1
Hilsenbeck, S.2
Gazitt, Y.3
-
46
-
-
10744220474
-
Arsenic trioxide is effective in the treatment of multiple myelomain SCID mice
-
Rousselot, P.; Larghero, J.; Labaume, S.; Poupon, J.; Chopin, M.; Dosquet, C.; Marolleau, J.P.; Janin, A.; Brouet, J.C.; Fermand, J.P.Arsenic trioxide is effective in the treatment of multiple myelomain SCID mice. Eur. J. Haematol., 2004, 72(3), 166-171.
-
(2004)
Eur. J. Haematol.
, vol.72
, Issue.3
, pp. 166-171
-
-
Rousselot, P.1
Larghero, J.2
Labaume, S.3
Poupon, J.4
Chopin, M.5
Dosquet, C.6
Marolleau, J.P.7
Janin, A.8
Brouet, J.C.9
Fermand, J.P.10
-
47
-
-
34447299646
-
Antimyeloma effects of arsenic trioxide are enhancedby melphalan, bortezomib and ascorbic acid
-
Campbell, R.A.; Sanchez, E.; Steinberg, J.A.; Baritaki, S.; Gordon, M.; Wang, C.; Shalitin, D.; Chen, H.; Pang, S.; Bonavida, B.; Said, J.; Berenson, J.R. Antimyeloma effects of arsenic trioxide are enhancedby melphalan, bortezomib and ascorbic acid. Br. J. Haematol., 2007, 138(4), 467-478.
-
(2007)
Br. J. Haematol.
, vol.138
, Issue.4
, pp. 467-478
-
-
Campbell, R.A.1
Sanchez, E.2
Steinberg, J.A.3
Baritaki, S.4
Gordon, M.5
Wang, C.6
Shalitin, D.7
Chen, H.8
Pang, S.9
Bonavida, B.10
Said, J.11
Berenson, J.R.12
-
48
-
-
0035437189
-
Ascorbic acid enhances arsenic trioxide-induced cytotoxicityin multiple myeloma cells
-
Grad, J.M.; Bahlis, N.J.; Reis, I.; Oshiro, M.M.; Dalton, W.S.; Boise, L.H. Ascorbic acid enhances arsenic trioxide-induced cytotoxicityin multiple myeloma cells. Blood, 2001, 98(3), 805-813.
-
(2001)
Blood
, vol.98
, Issue.3
, pp. 805-813
-
-
Grad, J.M.1
Bahlis, N.J.2
Reis, I.3
Oshiro, M.M.4
Dalton, W.S.5
Boise, L.H.6
-
49
-
-
33646884415
-
Efficacy and safety results withthe combination therapy of arsenic trioxide, dexamethasone, and ascorbic acid in multiple myeloma patients: A phase 2 trial
-
Abou-Jawde, R.M.; Reed, J.; Kelly, M.; Walker, E.; Andresen, S.; Baz, R.; Karam, M.A.; Hussein, M. Efficacy and safety results withthe combination therapy of arsenic trioxide, dexamethasone, and ascorbic acid in multiple myeloma patients: a phase 2 trial. Med.Oncol., 2006, 23(2), 263-272.
-
(2006)
Med.Oncol.
, vol.23
, Issue.2
, pp. 263-272
-
-
Abou-Jawde, R.M.1
Reed, J.2
Kelly, M.3
Walker, E.4
Andresen, S.5
Baz, R.6
Karam, M.A.7
Hussein, M.8
-
50
-
-
0036896388
-
Feasibility and correlates of arsenictrioxide combined with ascorbic acid-mediated depletion of intracellularglutathione for the treatment of relapsed/refractory multiplemyeloma
-
Bahlis, N.J.; McCafferty-Grad, J.; Jordan-McMurry, I.; Neil, J.; Reis, I.; Kharfan-Dabaja, M.; Eckman, J.; Goodman, M.; Fernandez, H.F.; Boise, L.H.; Lee, K.P. Feasibility and correlates of arsenictrioxide combined with ascorbic acid-mediated depletion of intracellularglutathione for the treatment of relapsed/refractory multiplemyeloma. Clin. Cancer Res., 2002, 8(12), 3658-3668.
-
(2002)
Clin. Cancer Res.
, vol.8
, Issue.12
, pp. 3658-3668
-
-
Bahlis, N.J.1
McCafferty-Grad, J.2
Jordan-McMurry, I.3
Neil, J.4
Reis, I.5
Kharfan-Dabaja, M.6
Eckman, J.7
Goodman, M.8
Fernandez, H.F.9
Boise, L.H.10
Lee, K.P.11
-
51
-
-
55249093243
-
TargetingMEK/MAPK signal transduction module potentiates ATO-inducedapoptosis in multiple myeloma cells through multiple signalingpathways
-
Lunghi, P.; Giuliani, N.; Mazzera, L.; Lombardi, G.; Ricca, M.; Corradi, A.; Cantoni, A.M.; Salvatore, L.; Riccioni, R.; Costanzo, A.; Testa, U.; Levrero, M.; Rizzoli, V.; Bonati, A. TargetingMEK/MAPK signal transduction module potentiates ATO-inducedapoptosis in multiple myeloma cells through multiple signalingpathways. Blood, 2008, 112(6), 2450-2462.
-
(2008)
Blood
, vol.112
, Issue.6
, pp. 2450-2462
-
-
Lunghi, P.1
Giuliani, N.2
Mazzera, L.3
Lombardi, G.4
Ricca, M.5
Corradi, A.6
Cantoni, A.M.7
Salvatore, L.8
Riccioni, R.9
Costanzo, A.10
Testa, U.11
Levrero, M.12
Rizzoli, V.13
Bonati, A.14
-
52
-
-
37249084060
-
P38 MAPK inhibition enhancingATO-induced cytotoxicity against multiple myeloma cells
-
Wen, J.; Cheng, H.Y.; Feng, Y.; Rice, L.; Liu, S.; Mo, A.; Huang, J.; Zu, Y.; Ballon, D.J.; Chang, C.C. P38 MAPK inhibition enhancingATO-induced cytotoxicity against multiple myeloma cells. Br.J. Haematol., 2008, 140(2), 169-180.
-
(2008)
Br.J. Haematol.
, vol.140
, Issue.2
, pp. 169-180
-
-
Wen, J.1
Cheng, H.Y.2
Feng, Y.3
Rice, L.4
Liu, S.5
Mo, A.6
Huang, J.7
Zu, Y.8
Ballon, D.J.9
Chang, C.C.10
-
53
-
-
0034680928
-
Inhibition of NF-kappa B activation by arsenitethrough reaction with a critical cysteine in the activation loopof Ikappa B kinase
-
Kapahi, P.; Takahashi, T.; Natoli, G.; Adams, S.R.; Chen, Y.; Tsien, R.Y.; Karin, M. Inhibition of NF-kappa B activation by arsenitethrough reaction with a critical cysteine in the activation loopof Ikappa B kinase. J. Biol. Chem., 2000, 275(46), 36062-36066.
-
(2000)
J. Biol. Chem.
, vol.275
, Issue.46
, pp. 36062-36066
-
-
Kapahi, P.1
Takahashi, T.2
Natoli, G.3
Adams, S.R.4
Chen, Y.5
Tsien, R.Y.6
Karin, M.7
-
54
-
-
18044395798
-
Proteasome inhibitor therapy in multiple myeloma
-
Chauhan, D.; Hideshima, T.; Mitsiades, C.; Richardson, P.; Anderson, K.C. Proteasome inhibitor therapy in multiple myeloma. Mol.Cancer Ther., 2005, 4(4), 686-692.
-
(2005)
Mol.Cancer Ther.
, vol.4
, Issue.4
, pp. 686-692
-
-
Chauhan, D.1
Hideshima, T.2
Mitsiades, C.3
Richardson, P.4
Anderson, K.C.5
-
55
-
-
0035300479
-
The proteasome inhibitorPS-341 inhibits growth, induces apoptosis, and overcomes drug resistancein human multiple myeloma cells
-
Hideshima, T.; Richardson, P.; Chauhan, D.; Palombella, V.J.; Elliott, P.J.; Adams, J.; Anderson, K.C. The proteasome inhibitorPS-341 inhibits growth, induces apoptosis, and overcomes drug resistancein human multiple myeloma cells. Cancer Res., 2001, 61(7), 3071-3076.
-
(2001)
Cancer Res.
, vol.61
, Issue.7
, pp. 3071-3076
-
-
Hideshima, T.1
Richardson, P.2
Chauhan, D.3
Palombella, V.J.4
Elliott, P.J.5
Adams, J.6
Anderson, K.C.7
-
56
-
-
33845952602
-
Phase II multicenter study of arsenictrioxide, ascorbic acid and dexamethasone in patients with relapsedor refractory multiple myeloma
-
Wu, K.L.; Beksac, M.; van Droogenbroeck, J.; Amadori, S.; Zweegman, S.; Sonneveld, P. Phase II multicenter study of arsenictrioxide, ascorbic acid and dexamethasone in patients with relapsedor refractory multiple myeloma. Haematologica, 2006, 91(12), 1722-1723.
-
(2006)
Haematologica
, vol.91
, Issue.12
, pp. 1722-1723
-
-
Wu, K.L.1
Beksac, M.2
van Droogenbroeck, J.3
Amadori, S.4
Zweegman, S.5
Sonneveld, P.6
-
57
-
-
11844266523
-
Efficacy of melphalan, arsenictrioxide, and ascorbic acid combination therapy (MAC) in relapsedand refractory multiple myeloma
-
Borad, M.J.; Swift, R.; Berenson, J.R. Efficacy of melphalan, arsenictrioxide, and ascorbic acid combination therapy (MAC) in relapsedand refractory multiple myeloma. Leukemia, 2005, 19(1), 154-156.
-
(2005)
Leukemia
, vol.19
, Issue.1
, pp. 154-156
-
-
Borad, M.J.1
Swift, R.2
Berenson, J.R.3
-
58
-
-
33748755948
-
Efficacy and safetyof melphalan, arsenic trioxide and ascorbic acid combination therapyin patients with relapsed or refractory multiple myeloma: Aprospective, multicentre, phase II, single-arm study
-
Berenson, J.R.; Boccia, R.; Siegel, D.; Bozdech, M.; Bessudo, A.; Stadtmauer, E.; Talisman Pomeroy, J.; Steis, R.; Flam, M.; Lutzky, J.; Jilani, S.; Volk, J.; Wong, S.F.; Moss, R.; Patel, R.; Ferretti, D.; Russell, K.; Louie, R.; Yeh, H.S.; Swift, R.A. Efficacy and safetyof melphalan, arsenic trioxide and ascorbic acid combination therapyin patients with relapsed or refractory multiple myeloma: aprospective, multicentre, phase II, single-arm study. Br. J. Haematol., 2006, 135(2), 174-183.
-
(2006)
Br. J. Haematol.
, vol.135
, Issue.2
, pp. 174-183
-
-
Berenson, J.R.1
Boccia, R.2
Siegel, D.3
Bozdech, M.4
Bessudo, A.5
Stadtmauer, E.6
Talisman Pomeroy, J.7
Steis, R.8
Flam, M.9
Lutzky, J.10
Jilani, S.11
Volk, J.12
Wong, S.F.13
Moss, R.14
Patel, R.15
Ferretti, D.16
Russell, K.17
Louie, R.18
Yeh, H.S.19
Swift, R.A.20
more..
-
59
-
-
34250194653
-
A phase I/II study of arsenic trioxide/bortezomib/ascorbic acid combination therapy for the treatmentof relapsed or refractory multiple myeloma
-
Berenson, J.R.; Matous, J.; Swift, R.A.; Mapes, R.; Morrison, B.; Yeh, H.S. A phase I/II study of arsenic trioxide/bortezomib/ascorbic acid combination therapy for the treatmentof relapsed or refractory multiple myeloma. Clin. Cancer Res., 2007, 13(6), 1762-1768.
-
(2007)
Clin. Cancer Res.
, vol.13
, Issue.6
, pp. 1762-1768
-
-
Berenson, J.R.1
Matous, J.2
Swift, R.A.3
Mapes, R.4
Morrison, B.5
Yeh, H.S.6
-
60
-
-
0034743735
-
Co-treatment with As2O3 enhances selectivecytotoxic effects of STI-571 against Brc-Abl-positive acuteleukemia cells
-
Porosnicu, M.; Nimmanapalli, R.; Nguyen, D.; Worthington, E.; Perkins, C.; Bhalla, K.N. Co-treatment with As2O3 enhances selectivecytotoxic effects of STI-571 against Brc-Abl-positive acuteleukemia cells. Leukemia, 2001, 15(5), 772-778.
-
(2001)
Leukemia
, vol.15
, Issue.5
, pp. 772-778
-
-
Porosnicu, M.1
Nimmanapalli, R.2
Nguyen, D.3
Worthington, E.4
Perkins, C.5
Bhalla, K.N.6
-
61
-
-
9144271748
-
In vitro efficacy of combined treatment dependson the underlying mechanism of resistance in imatinibresistantBcr-Abl-positive cell lines
-
La Rosee, P.; Johnson, K.; Corbin, A.S.; Stoffregen, E.P.; Moseson, E.M.; Willis, S.; Mauro, M.M.; Melo, J.V.; Deininger, M.W.; Druker, B.J. In vitro efficacy of combined treatment dependson the underlying mechanism of resistance in imatinibresistantBcr-Abl-positive cell lines. Blood, 2004, 103(1), 208-215.
-
(2004)
Blood
, vol.103
, Issue.1
, pp. 208-215
-
-
La Rosee, P.1
Johnson, K.2
Corbin, A.S.3
Stoffregen, E.P.4
Moseson, E.M.5
Willis, S.6
Mauro, M.M.7
Melo, J.V.8
Deininger, M.W.9
Druker, B.J.10
-
62
-
-
0032032270
-
Bcr-Abl exerts its antiapoptoticeffect against diverse apoptotic stimuli through blockage of mitochondrial release of cytochrome C and activation of caspase-3
-
Amarante-Mendes, G.P.; Naekyung Kim, C.; Liu, L.; Huang, Y.; Perkins, C.L.; Green, D.R.; Bhalla, K. Bcr-Abl exerts its antiapoptoticeffect against diverse apoptotic stimuli through blockage of mitochondrial release of cytochrome C and activation of caspase-3.Blood, 1998, 91(5), 1700-1705.
-
(1998)
Blood
, vol.91
, Issue.5
, pp. 1700-1705
-
-
Amarante-Mendes, G.P.1
Naekyung Kim, C.2
Liu, L.3
Huang, Y.4
Perkins, C.L.5
Green, D.R.6
Bhalla, K.7
-
63
-
-
0344844465
-
Arsenic trioxide inhibits translation of mRNA of bcr-abl, resulting in attenuation of Bcr-Abl levels and apoptosis of human leukemia cells
-
Nimmanapalli, R.; Bali, P.; O'Bryan, E.; Fuino, L.; Guo, F.; Wu, J.; Houghton, P.; Bhalla, K. Arsenic trioxide inhibits translation of mRNA of bcr-abl, resulting in attenuation of Bcr-Abl levels and apoptosis of human leukemia cells. Cancer Res., 2003, 63(22), 7950-7958.
-
(2003)
Cancer Res.
, vol.63
, Issue.22
, pp. 7950-7958
-
-
Nimmanapalli, R.1
Bali, P.2
O'Bryan, E.3
Fuino, L.4
Guo, F.5
Wu, J.6
Houghton, P.7
Bhalla, K.8
-
64
-
-
34347242113
-
EnhancedBcr-Abl-specific antileukemic activity of arsenic trioxide (Trisenox)through glutathione-depletion in imatinib-resistant cells
-
Konig, H.; Hartel, N.; Schultheis, B.; Schatz, M.; Lorentz, C.; Melo, J.V.; Hehlmann, R.; Hochhaus, A.; La Rosee, P. EnhancedBcr-Abl-specific antileukemic activity of arsenic trioxide (Trisenox)through glutathione-depletion in imatinib-resistant cells.Haematologica, 2007, 92(6), 838-841.
-
(2007)
Haematologica
, vol.92
, Issue.6
, pp. 838-841
-
-
Konig, H.1
Hartel, N.2
Schultheis, B.3
Schatz, M.4
Lorentz, C.5
Melo, J.V.6
Hehlmann, R.7
Hochhaus, A.8
La Rosee, P.9
-
65
-
-
32644449422
-
Coordinationof intrinsic, extrinsic, and endoplasmic reticulum-mediated apoptosisby imatinib mesylate combined with arsenic trioxide in chronicmyeloid leukemia
-
Du, Y.; Wang, K.; Fang, H.; Li, J.; Xiao, D.; Zheng, P.; Chen, Y.; Fan, H.; Pan, X.; Zhao, C.; Zhang, Q.; Imbeaud, S.; Graudens, E.; Eveno, E.; Auffray, C.; Chen, S.; Chen, Z.; Zhang, J. Coordinationof intrinsic, extrinsic, and endoplasmic reticulum-mediated apoptosisby imatinib mesylate combined with arsenic trioxide in chronicmyeloid leukemia. Blood, 2006, 107(4), 1582-1590.
-
(2006)
Blood
, vol.107
, Issue.4
, pp. 1582-1590
-
-
Du, Y.1
Wang, K.2
Fang, H.3
Li, J.4
Xiao, D.5
Zheng, P.6
Chen, Y.7
Fan, H.8
Pan, X.9
Zhao, C.10
Zhang, Q.11
Imbeaud, S.12
Graudens, E.13
Eveno, E.14
Auffray, C.15
Chen, S.16
Chen, Z.17
Zhang, J.18
-
66
-
-
0001686739
-
Multiple BCR-ABL kinase domain mutationsconfer polyclonal resistance to the tyrosine kinase inhibitorimatinib (STI571) in chronic phase and blast crisis chronic myeloidleukemia
-
Shah, N.P.; Nicoll, J.M.; Nagar, B.; Gorre, M.E.; Paquette, R.L.; Kuriyan, J.; Sawyers, C.L. Multiple BCR-ABL kinase domain mutationsconfer polyclonal resistance to the tyrosine kinase inhibitorimatinib (STI571) in chronic phase and blast crisis chronic myeloidleukemia. Cancer Cell, 2002, 2(2), 117-125.
-
(2002)
Cancer Cell
, vol.2
, Issue.2
, pp. 117-125
-
-
Shah, N.P.1
Nicoll, J.M.2
Nagar, B.3
Gorre, M.E.4
Paquette, R.L.5
Kuriyan, J.6
Sawyers, C.L.7
-
67
-
-
34447544253
-
BCR-ABL tyrosine kinase inhibitors for chronicmyelogenous leukemia
-
Schiffer, C.A. BCR-ABL tyrosine kinase inhibitors for chronicmyelogenous leukemia. N. Engl. J. Med., 2007, 357(3), 258-265.
-
(2007)
N. Engl. J. Med.
, vol.357
, Issue.3
, pp. 258-265
-
-
Schiffer, C.A.1
-
68
-
-
0033891886
-
Retinoic acid induces the degradation of theleukemogenic protein encoded by the promyelocytic leukemia genefused to the retinoic acid receptor alpha gene
-
Wolf, G.; Smas, C.M. Retinoic acid induces the degradation of theleukemogenic protein encoded by the promyelocytic leukemia genefused to the retinoic acid receptor alpha gene. Nutr. Rev., 2000, 58(7), 211-214.
-
(2000)
Nutr. Rev.
, vol.58
, Issue.7
, pp. 211-214
-
-
Wolf, G.1
Smas, C.M.2
-
69
-
-
77950826446
-
Arsenic trioxide controls the fate of the PML-RARalphaoncoprotein by directly binding PML
-
Zhang, X.W.; Yan, X.J.; Zhou, Z.R.; Yang, F.F.; Wu, Z.Y.; Sun, H.B.; Liang, W.X.; Song, A.X.; Lallemand-Breitenbach, V.; Jeanne, M.; Zhang, Q.Y.; Yang, H.Y.; Huang, Q.H.; Zhou, G.B.; Tong, J.H.; Zhang, Y.; Wu, J.H.; Hu, H.Y.; de The, H.; Chen, S.J.; Chen, Z. Arsenic trioxide controls the fate of the PML-RARalphaoncoprotein by directly binding PML. Science, 2010, 328(5975), 240-243.
-
(2010)
Science
, vol.328
, Issue.5975
, pp. 240-243
-
-
Zhang, X.W.1
Yan, X.J.2
Zhou, Z.R.3
Yang, F.F.4
Wu, Z.Y.5
Sun, H.B.6
Liang, W.X.7
Song, A.X.8
Lallemand-Breitenbach, V.9
Jeanne, M.10
Zhang, Q.Y.11
Yang, H.Y.12
Huang, Q.H.13
Zhou, G.B.14
Tong, J.H.15
Zhang, Y.16
Wu, J.H.17
Hu, H.Y.18
de The, H.19
Chen, S.J.20
Chen, Z.21
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