Structural barriers to ART adherence in Southern Africa: Challenges and potential ways forward

Global Public Health

Volumn 6, Issue 1, 2011, Pages 83-97

  Kagee, A ^a   Remien, R H ^b   Berkman, A ^c   Hoffman, S ^c   Campos, L ^d   Swartz, L ^a  

^a STELLENBOSCH UNIVERSITY   (South Africa)

^b NEW YORK STATE PSYCHIATRIC INSTITUTE   (United States)

^c Columbia University ^*  (United States)

^d FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

Author keywords

Adherence; Antiretroviral therapy; Structural barriers

Indexed keywords

ANTIRETROVIRUS AGENT;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ARTICLE; CULTURAL FACTOR; HEALTH CARE ACCESS; HEALTH CARE FACILITY; HEALTH CARE NEED; HEALTH EDUCATION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MENTAL HEALTH SERVICE; MIGRATION; PATIENT COMPLIANCE; PATIENT COUNSELING; POLITICS; POVERTY; PRIORITY JOURNAL; SOCIAL SUPPORT; SOCIOECONOMICS; SOUTH AFRICA;

ANTI-RETROVIRAL AGENTS; CULTURE; HEALTH PROMOTION; HEALTH SERVICES ACCESSIBILITY; HIV INFECTIONS; HUMANS; PATIENT COMPLIANCE; POLITICS; POVERTY; PREJUDICE; SOUTH AFRICA;

EID: 78649816064     PISSN: 17441692     EISSN: 17441706     Source Type: Journal    
DOI: 10.1080/17441691003796387     Document Type: Article

References (49)

1. Antelman, G., Kaaya, S., Wei, R., Mbwambo, J., Msamanga, G.I., Fawzi, W.W., and Fawzi, M.C., 2007. Depressive symptoms increase risk of HIV disease progression and mortality among women in Tanzania. Journal of Acquired Immune Deficiency Syndrome, 4, 470-477.
2. Bardeguez, A.D., Lindsey, J.C., Shannon, M., Tuomala, R.E., Cohn, S.E., Smith, E., Stek, A., Buschur, S., Cotter, A., Bettica, L., and Read, J.S., 2008. Adherence to antiretrovirals among US women during and after pregnancy. Journal of Acquired Immune Deficiency Syndrome, 48, 408-417.
3. Beck, D., 2004. Men and ARVS: how does being a man affect access to antiretroviral therapy in South Africa. Centre for Social Science Research, Working paper No. 80. Cape Town: University of Cape Town, 1-32.
4. Bekker, L.G., Myer, L., Orrel, C., Lawn, S., and Wood, R., 2006. Rapid scale-up of a community-based HIV treatment service: programme performance over 3 consecutive years in Guguletu, South Africa. South African Medical Journal, 96, 315-320.
5. Braitstein, P., Boulle, A., Nash, D., Brinkhof, M.W.G., Dabis, F., Laurent, C., Schechter, M., Tuboi, S.H., Sprinz, E., Miotti, P., Hosseinipour, M., May, M., Egger, M., Bangsberg, D.R., and Low, N., 2008. Gender and the use of antiretroviral treatment in resource-constrained settings: findings from a multicenter collaboration. Journal of Women's Health, 17, 47-55.
6. Breen, A., Swartz, L., Joska, J., Flisher, A.J., and Corrigall, J., 2007. Adherence to treatment in poorer countries: a new research direction. Psychiatric Services, 58, 567-568.
7. Bronfenbrenner, U., 1972. Influences on human development. Fort Worth, TX: Dryden Press.
8. Brown, L., MacIntyre, K., and Trujillo, L., 2003. Interventions to reduce HIV/AIDS stigma: what have we learned? AIDS Education and Prevention, 15, 49-69.
9. Coetzee, D., Boulle, A., Hildebrand, K., Asselman, V., Van Cutsem, G., and Goemaere, E., 2004. Promoting adherence to antiretroviral therapy: the experience from a primary care setting in Khayelitsha, South Africa. AIDS, 18, S27-S31.
10. Collins, P., Holman, A.R., Freeman, M.C., and Patel, V., 2006.What is the relevance of mental health to HIV/AIDS care and treatment programs in developing countries? A systematic review. AIDS, 20, 1571-1582.
11. Ewart, C.K., 1991. Social action theory for a public health psychology. American Psychologist, 46, 931-946.
12. Friedland, G., Harries, A., and Coetzee, D., 2007. Implementation issues in tuberculosis/HIV program collaboration and integration: 3 case studies. Journal of Infectious Diseases, 196, S114-S123.
13. Gill, C.J., Hamer, D.H., Simon, J.L., Thea, D.M., and Sabin, L.L., 2005. No room for complacency about adherence to antiretroviral therapy in sub-Saharan Africa. AIDS, 19, 1243-1249.
14. Gupta, G., 2005. Remarks on women and AIDS. Washington, DC: International Centre for Research on Women.
15. Hardon, A.P., Akurut, D., Comoro, C., Ekezie, C., Irunde, H.F., Gerrits, T., Kglatwane, J., Kinsman, J., Kwasa, R., Maridadi, J., Moroka, T.M., Moyo, S., Nakiyemba, A., Nsimba, S, Ogenyi, R., Oyabba, T., Temu, F., and Laing, R., 2007. Hunger, waiting time and transport costs: time to confront challenges to ART adherence in Africa. AIDS Care, 19 (5), 658-665.
16. Holstad, M.K., Pace, J.C., De, A.K., and Ura, D.R., 2006. Factors associated with adherence to antiretroviral therapy. Journal of the Association of Nurses in AIDS Care, 17, 4-15.
17. Jack, C., Lalloo, U., Karim, Q.A., Karim, S.A., El-Sadr, W., Cassol, S., and Friedland, G., 2004. A pilot study of once-daily antiretroviral therapy integrated with tuberculosis directly observed therapy in a resource-limited setting. Journal of Acquired Immune Deficiency Syndrome, 36, 929-934.
18. Kagee, A., Le Roux, M., and Dick, J., 2007. Treatment adherence among primary care patients in a historically disadvantaged community in South Africa: a qualitative study. Journal of Health Psychology, 12, 444-460.
19. Kale, R., 1995. South Africa's Health. Traditional healers in South Africa: a parallel health care system. British Medical Journal, 310, 1182-1185.
20. Kalichman, S.C. and Simbayi, L., 2004. Traditional beliefs about the cause of AIDS and AIDS-related stigma in South Africa. AIDS Care, 16, 572-580.
21. Kaplan, W.A., 2006. Can the ubiquitous power of mobile phones be used to improve health outcomes in developing countries? Globalization and Health, 2, 1-14.
22. Kilbourne, A.M., Reynolds, C.F., Good, C.B., Sereika, S.M., Justice, A.C., and Fine, M.J., 2005. How does depression influence diabetes medication adherence in older patients? American Journal of Geriatric Psychiatry, 13, 202-210.
23. Klitzman, R.L., Kirshenbaum, S.B., Dodge, B., Remien, R.H., Ehrhardt, A.A., Johnson, M.O., Kittel, L.E., Daya, S., Morin, S.F., Kelly, J., and Lightfoot, M., 2004. Intricacies and inter-relationships between HIV disclosure and HAART: a qualitative study. AIDS Care, 16, 628-640.
24. Malta, M., Petersen, M.L., Clair, S., Freitas, F., and Bastos, F., 2005. Adherence to antiretroviral therapy: a qualitative study with physicians from Rio de Janeiro, Brazil. Cadernos Saúde Pública, 21 (5), 1424-1432.
25. Medicines Sans Frontiers, 2007. Help wanted: MSF report [online]. Available from: http://www.msf.org [Accessed 18 September 2007].
26. Mills, E.J., Nachega, J.B., Buchan, I., Orbinski, J., Attaran, A., Singh, S., Rachlis, B., Wu, P., Cooper, C., Thabane, L., Wilson, K., Guyatt, G.H., and Bangsberg, D.R., 2006. Adherence to antiretroviral therapy in sub-Saharan Africa and North America: a meta-analysis. Journal of the American Medical Association, 296, 679-690.
27. Mukherjee, J.S., Ivers, L., Leandre, F., Farmer, P., and Behforouz, H., 2006. Antiretroviral therapy in resource-poor settings: decreasing barriers to access and promoting adherence. Journal of Acquired Immune Deficiency Syndrome, 43 (Suppl. 1), S123-S126.
28. Nattrass, N., 2006. AIDS, science and governance: the battle over antiretroviral therapy in post-apartheid South Africa. Southern African HIV Clinicians Journal [online]. Available from: http://www.aidstruth.org/Rolling-out-HAART-in-South-Africa.pdf [Accessed 18 September 2007].
29. Orrell, C., Bangsberg, D.R., Badri, M., and Wood, R., 2003. Adherence is not a barrier to successful antiretroviral therapy in South Africa. AIDS, 17, 1369-1375.
30. Parker, R. and Aggleton, P., 2003. HIV and AIDS-related stigma and discrimination: a conceptual framework and implications for action. Social Science & Medicine, 57, 13-24.
31. Patel, V., Saraceno, B., and Kleinman, A., 2006. Beyond evidence: the moral case for international mental health. American Journal of Psychiatry, 163, 1312-1315.
32. Paterson, D.L., Swindells, S., Mohr, J., Brester, M., Vergis, E.N., Squier, C., Wagener, M.M., and Singh, N., 2000. Adherence to protease inhibitor therapy and outcomes in patients with HIV infection. Annals of Internal Medicine, 133, 21-30.
33. Pearson, C.R., Micek, M., Simoni, J.M., Matediana, E., Martin, D.P., and Gloyd, S., 2006. Modified directly observed therapy to facilitate highly active antiretroviral therapy adherence in Beira, Mozambique. Development and implementation. Journal of Acquired Immune Deficiency Syndrome, 43 (Suppl. 1), S134-S141.
34. Pence, B.W., Miller, W.C., Gaynes, B.N., and Eron, J.J., 2007. Psychiatric illness and virologic response in patients initiating highly active antiretroviral therapy. Journal of Acquired Immune Deficiency Syndrome, 44, 159-166.
35. Remien, R.H., Berkman, A., Myer, L., Bastos, F.I., Kagee, A., and El-Sadr, W., 2008. Integrating HIV care and HIV prevention: legal, policy and programmatic recommendation. AIDS, 22 (Suppl. 0), S1-S9.
36. Rohleder, P. and Swartz, L., 2005. What I've noticed what they need is the stats: community counsellors and HIV. AIDS Care, 17, 397-406.
37. Sayles, J.N., Wong, M.D., and Cunningham, W.E., 2006. The inability to take medications openly at home: does it help explain gender disparities in HAART use? Journal of Women's Health, 15, 173-181.
38. Schinke, S.P., DeNoia, J., and Glassman, J.R., 2004. Computer-mediated intervention to prevent drug abuse and violence among high-risk youth. Addictive Behaviour, 29, 225-229.
39. Shriver, M., Everett, C., and Morin, S., 2000. Structural interventions to encourage primary HIV prevention among people living with HIV. AIDS, 14 (Suppl. 1), 57-62.
40. Simoni, J.M., Pearson, C.R., Pantalone, D.W., Marks, G., and Crepaz, N., 2006. Efficacy of interventions in improving highly active antiretroviral therapy adherence and HIV-1 RNA viral load: a meta-analytic review of randomised controlled trials. Journal of Acquired Immune Deficiency Syndrome, 43 (Suppl. 1), S23-S35.
41. Swartz, L., 1998. Culture and mental health: a Southern African view. Oxford: Oxford University Press.
42. Swartz, L. and Dick, J., 2002. Managing chronic diseases in less developed countries. British Medical Journal, 325, 914-915.
43. Tucker, J.S., Orlando, M., Burnam, M.A., Sherbourne, C.D., Kung, F.Y., and Gifford, A.L., 2004. Psychosocial mediators of antiretroviral nonadherence in HIV-positive adults with substance use and mental health problems. Health Psychology, 23, 363-370.
44. UNAIDS/WHO, 2007. AIDS epidemic update. Geneva: World Health Organisation.
45. Walker, L., Reid, G., and Cornell, M., 2004. Waiting to happen. Cape Town: Double Storey Books.
46. White, H.D., 2005. Adherence and outcomes: it's more than taking the pills. The Lancet [online], 1989-1991. Available from: http://www.sciencedirect.com/science/journal/01406736366 [Accessed 28 April 2010].
47. WHO (World Health Organisation), 2001. Atlas country profiles on mental health resource. Geneva: WHO.
48. WHO (World Health Organisation), 2007. Prioritizing second-line antiretroviral drugs for adults and adolescents: a public health approach: report of a WHO working group meeting. Geneva: WHO.
49. WHO (World Health Organisation), 2008. Towards universal access: scaling up priority HIV/ AIDS interventions in the health sector-progress report. Geneva: WHO.