Anti-pancreatic antibody in Turkish patients with inflammatory bowel disease and first-degree relatives

World Journal of Gastroenterology

Volumn 16, Issue 45, 2010, Pages 5732-5738

  Demirsoy, Huseyin ^a   Ozdil, Kamil ^a   Ersoy, Ozdal ^a   Kesici, Besir ^a   Karaca, Cetin ^a   Alkim, Canan ^a   Akbayir, Nihat ^a   Erdem, Levent Kamil ^a   Onuk, Mehmet Derya ^a   Beyzadeoglu, Hulya Tugrul ^b  

^a SISLI ETFAL TRAINING AND RESEARCH HOSPITAL   (Turkey)

^b Institute of Hygiene   (Turkey)

Author keywords

Anti pancreatic antibody; Anti Saccharomyces cerevisiae antibody; Crohn's disease; Inflammatory bowel disease; Ulcerative colitis;

Indexed keywords

ANTIBODY; PANCREAS ANTIBODY; UNCLASSIFIED DRUG;

ADULT; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; CROHN DISEASE; DISEASE ACTIVITY; ENTERITIS; FEMALE; GASTROINTESTINAL SYMPTOM; HUMAN; IMMUNOFLUORESCENCE TEST; MAJOR CLINICAL STUDY; MALE; RELATIVE; SACCHAROMYCES CEREVISIAE; SENSITIVITY AND SPECIFICITY; TURKEY (REPUBLIC); ULCERATIVE COLITIS;

EID: 78649815509     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v16.i45.5732     Document Type: Article

References (25)

1. Silverberg MS, Daly MJ, Moskovitz DN, Rioux JD, McLeod RS, Cohen Z, Greenberg GR, Hudson TJ, Siminovitch KA, Steinhart AH. Diagnostic misclassification reduces the ability to detect linkage in inflammatory bowel disease genetic studies. Gut 2001; 49: 773-776
2. Sandborn WJ. Serologic markers in inflammatory bowel disease: state of the art. Rev Gastroenterol Disord 2004; 4: 167-174
3. Lakatos PL, Altorjay I, Szamosi T, Palatka K, Vitalis Z, Tumpek J, Sipka S, Udvardy M, Dinya T, Lakatos L, Kovacs A, Molnar T, Tulassay Z, Miheller P, Barta Z, Stocker W, Papp J, Veres G, Papp M. Pancreatic autoantibodies are associated with reactivity to microbial antibodies, penetrating disease behavior, perianal disease, and extraintestinal manifestations, but not with NOD2/CARD15 or TLR4 genotype in a Hungarian IBD cohort. Inflamm Bowel Dis 2009; 15: 365-374
4. Vermeire S, Van Assche G, Rutgeerts P. Should family members of IBD patients be screened for CARD15/NOD2 mutations? Inflamm Bowel Dis 2008; 14 Suppl 2: S190-S191
5. Seibold F, Mörk H, Tanza S, Müller A, Holzhüter C, Weber P, Scheurlen M. Pancreatic autoantibodies in Crohn's disease: a family study. Gut 1997; 40: 481-484
6. Targan SR, Landers CJ, Cobb L, MacDermott RP, Vidrich A. Perinuclear anti-neutrophil cytoplasmic antibodies are spontaneously produced by mucosal B cells of ulcerative colitis patients. J Immunol 1995; 155: 3262-3267
7. Seibold F, Weber P, Jenss H, Wiedmann KH. Antibodies to a trypsin sensitive pancreatic antigen in chronic inflammatory bowel disease: specific markers for a subgroup of patients with Crohn's disease. Gut 1991; 32: 1192-1197
8. Shanahan F. Neutrophil autoantibodies in inflammatory bowel disease: are they important? Gastroenterology 1994; 107: 586-589
9. Stöcker W, Otte M, Ulrich S, Normann D, Stöcker K, Jantschek G. [Autoantibodies against the exocrine pancreas and against intestinal goblet cells in the diagnosis of Crohn's disease and ulcerative colitis] Dtsch Med Wochenschr 1984; 109: 1963-1969
10. Folwaczny C, Noehl N, Endres SP, Loeschke K, Fricke H. Antineutrophil and pancreatic autoantibodies in first-degree relatives of patients with inflammatory bowel disease. Scand J Gastroenterol 1998; 33: 523-528
11. Koutroubakis IE, Drygiannakis D, Karmiris K, Drygiannakis I, Makreas S, Kouroumalis EA. Pancreatic autoantibodies in Greek patients with inflammatory bowel disease. Dig Dis Sci 2005; 50: 2330-2334
12. Goischke EM, Zilly W. [Clinical importance of organspecific antibodies in ulcerative colitis and Crohn disease] Z Gastroenterol 1992; 30: 319-324
13. Nishimori I, Yamamoto Y, Okazaki K, Morita M, Onodera M, Kino J, Tamura S, Yamamoto Y. Identification of autoantibodies to a pancreatic antigen in patients with idiopathic chronic pancreatitis and Sjögren's syndrome. Pancreas 1994; 9: 374-381
14. Joossens S, Vermeire S, Van Steen K, Godefridis G, Claessens G, Pierik M, Vlietinck R, Aerts R, Rutgeerts P, Bossuyt X. Pancreatic autoantibodies in inflammatory bowel disease. Inflamm Bowel Dis 2004; 10: 771-777
15. Desplat-Jégo S, Johanet C, Escande A, Goetz J, Fabien N, Olsson N, Ballot E, Sarles J, Baudon JJ, Grimaud JC, Veyrac M, Chamouard P, Humbel RL. Update on Anti-Saccharomyces cerevisiae antibodies, anti-nuclear associated anti-neutrophil antibodies and antibodies to exocrine pancreas detected by indirect immunofluorescence as biomarkers in chronic inflammatory bowel diseases: results of a multicenter study. World J Gastroenterol 2007; 13: 2312-2318
16. Klebl FH, Bataille F, Huy C, Hofstädter F, Schölmerich J, Rogler G. Association of antibodies to exocrine pancreas with subtypes of Crohn's disease. Eur J Gastroenterol Hepatol 2005; 17: 73-77
17. Sandborn WJ, Loftus EV Jr, Colombel JF, Fleming KA, Seibold F, Homburger HA, Sendid B, Chapman RW, Tremaine WJ, Kaul DK, Wallace J, Harmsen WS, Zinsmeister AR, Targan SR. Evaluation of serologic disease markers in a population-based cohort of patients with ulcerative colitis and Crohn's disease. Inflamm Bowel Dis 2001; 7: 192-201
18. Conrad K, Schmechta H, Klafki A, Lobeck G, Uhlig HH, Gerdi S, Henker J. Serological differentiation of inflammatory bowel diseases. Eur J Gastroenterol Hepatol 2002; 14: 129-135
19. Shanahan F. Antibody 'markers' in Crohn's disease: opportunity or overstatement? Gut 1997; 40: 557-558
20. Müller-Ladner U, Schölmerich J. Pancreatic autoantibodies in Crohn's disease. Eur J Clin Invest 1999; 29: 46-47
21. Seibold F, Scheurlen M, Müller A, Jenss H, Weber P. Impaired pancreatic function in patients with Crohn's disease with and without pancreatic autoantibodies. J Clin Gastroenterol 1996; 22: 202-206
22. Lawrance IC, Hall A, Leong R, Pearce C, Murray K. A comparative study of goblet cell and pancreatic exocine autoantibodies combined with ASCA and pANCA in Chinese and Caucasian patients with IBD. Inflamm Bowel Dis 2005; 11: 890-897
23. Farmer RG, Michener WM, Mortimer EA. Studies of family history among patients with inflammatory bowel disease. Clin Gastroenterol 1980; 9: 271-277
24. Orholm M, Fonager K, Sørensen HT. Risk of ulcerative colitis and Crohn's disease among offspring of patients with chronic inflammatory bowel disease. Am J Gastroenterol 1999; 94: 3236-3238
25. Monsén U, Bernell O, Johansson C, Hellers G. Prevalence of inflammatory bowel disease among relatives of patients with Crohn's disease. Scand J Gastroenterol 1991; 26: 302-306