Pilot study of intravesical instillation of two new generation anthracycline antibiotics in prevention of superficial bladder cancer recurrence

Chinese Medical Journal

Volumn 123, Issue 23, 2010, Pages 3422-3426

  Chen, Si Yang ^a   Du, Lin Dong ^a   Zhang, Yu Hai ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

Epirubicin; Hydroxycamptothecin; Intravesical instillation; Pirarubicin; Superficial bladder cancer

Indexed keywords

10 HYDROXYCAMPTOTHECIN; EPIRUBICIN; PIRARUBICIN;

ADULT; AGED; ARTICLE; BLADDER CANCER; BLADDER CONTRACTION; CANCER RECURRENCE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFICACY; DRUG SAFETY; DYSURIA; FEMALE; HEMATURIA; HUMAN; MAJOR CLINICAL STUDY; MALE; PILOT STUDY; POLLAKISURIA; RANDOMIZED CONTROLLED TRIAL; SIDE EFFECT; SUPERFICIAL BLADDER CANCER; TRANSURETHRAL RESECTION;

ADMINISTRATION, INTRAVESICAL; ADULT; AGED; ANTHRACYCLINES; ANTIBIOTICS, ANTINEOPLASTIC; FEMALE; HUMANS; MALE; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; PILOT PROJECTS; URINARY BLADDER NEOPLASMS;

EID: 78649806743     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: 10.3760/cma.j.issn.0366-6999.2010.23.009     Document Type: Article

References (14)

1. Li NC, Xiao YX, Song Y, Zhang K, Yuan JF, Gong K, et al. Intravesical instillation of pirarubicin for preventing postoperativerecurrence of superficial bladder cancer in 132 patients. Chin J Clin Oncol (Chin) 2005; 32: 1245-1247.
2. McHugh LA, Griffiths TR. T1G3 transitional cell carcinoma of the bladder: recurrence, progression and survival. BJU Int 2004; 93: 60-63.
3. Giesbers AA, Van Helsdingen PJ, Kramer AE. Recurrence of superficial bladder carcinoma after intravesical instillation of mitomycin-C. Comparison of exposure times. Br J Urol 1989; 63: 176-179.
4. Matsumura Y. Cooperative study of therapy of superficial bladder cancer by intravesical instillation of pirarubicin. Am J Clin Oncol 1990; 13 Suppl 1: s5-s10.
5. Nomata K, Noguchi M, Kanetake H, Tsuda N, Hayashi M, Yamashita S, et al. Intravesical adjuvant chemotherapy for superficial transitional cell bladder carcinoma: results of a randomized trial with epirubicin comparing short-term versus long-term maintenance treatment. Cancer Chemother Pharmacol 2002; 50: 266-270.
6. Kuroda M, Niijima T, Kotake T, Akaza H, Hinotsu S; 6th Trial of the Japanese Urological Cancer Research Group. Effect of prophylactic treatment with intravesical epirubicin on recurrence of superficial bladder cancer - The 6th Trial of the Japanese Urological Cancer Research Group (JUCRG): a randomized trial of intravesical epirubicin at dose of 20 mg/40 ml, 30 mg/40 ml, 40 mg/40 ml. Eur Urol 2004; 45: 600-605.
7. Imamoǧlu MA, Bakirtaş H, Yiǧitbaşi O, Ersoy H, Sertçelik AN. Intravesical epirubicin treatment following TUR in superficial bladder tumours. Arch Esp Urol 2001; 54: 1147-1153.
8. Onrust SV, Wiseman LR, Goa KL. Epirubicin: a review of its intravesical use in superficial bladder cancer. Drugs Aging 1999; 15: 307-333.
9. Wu WJ, Peng JJ, Ma J. Effect of intravesical instillation of hydroxycamptothecin and pirarubicin in for preventing postoperative recurrence of superficial bladder cancer. Modern Hospital 2008; 8: 22-24.
10. Zeng YK, Shen HB, Qi J, Gu ZQ, Zhang L, Kang J, et al. Effect of combined administration of hydroxycamptothecin and pirarubicin in human bladder cancer cell line 5637. J Clin Urol 2008; 23: 617-629.
11. Hinotsu S, Akaza H, Ohashi Y, Kotake T. Intravesical chemotherapy for maximum prophylaxis of new early phase superficial bladder carcinoma treated by transurethral resection: a combined analysis of trials by the Japanese Urological Cancer Research Group using smoothed hazard function. Cancer 1999; 86: 1818-1826.
12. Shinohara N, Nonomura K, Tanaka M, Nagamori S, Takakura F, Seki T, et al. Prophylactic chemotherapy with anthracyclines (adriamycin, epirubicin, and pirarubicin) for primary superficial bladder cancer. The Hokkaido University Bladder Cancer Collaborative Group. Cancer Chemother Pharmacol 1994; 35 Suppl: s41-s45.
13. Oosterlinck W, Kurth KH, Schröder F, Bultinck J, Hammond B, Sylvester R. A prospective European Organization for Research and Treatment of Cancer Genitourinary Group randomized trial comparing transurethral resection followed by a single intravesical instillation of epirubicin or water in single stage Ta, T1 papillary carcinoma of the bladder. J Urol 1993; 149: 749-752.
14. Bassi P, Spinadin R, Longo F, Saraeb S, Pappagallo GL, Zattoni F, et al. Delayed high-dose intravesical epirubicin therapy of superficial bladder cancer. A way to reduce the side effects and increase the efficacy - a phase 2 trial. Urol Int 2002; 68: 216-219.