Mitogen-activated protein kinase in endothelin-1-induced cardiac differentiation of mouse embryonic stem cells

Journal of Cellular Biochemistry

Volumn 111, Issue 6, 2010, Pages 1619-1628

  Chen, Ming ^a   Lin, Yong Qing ^a   Xie, Shuang Lun ^a   Wang, Jing Feng ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

cardiomyocyte; embryonic stem cells; endothelin 1; mitogen activated protein kinase

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; ENDOTHELIN 1; ENDOTHELIN RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; TRANSCRIPTION FACTOR GATA 4; TRANSCRIPTION FACTOR NKX2.5; TROPONIN;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CLINICAL ASSESSMENT; CONTROLLED STUDY; EMBRYO; EMBRYONIC STEM CELL; HEART DEVELOPMENT; HEART MUSCLE CELL; HEART MUSCLE CONDUCTION SYSTEM; IMMUNOCYTOCHEMISTRY; MAJOR HISTOCOMPATIBILITY COMPLEX; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; SPINDLE CELL; UPREGULATION;

ANIMALS; BUTADIENES; CELL DIFFERENTIATION; CELL LINE; EMBRYOID BODIES; EMBRYONIC STEM CELLS; ENDOTHELIN-1; ENZYME INHIBITORS; IMIDAZOLES; IMMUNOHISTOCHEMISTRY; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; MYOCYTES, CARDIAC; NITRILES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PYRIDINES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 78649795216     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.22895     Document Type: Article

References (39)

1. Arai H, Hori S, Aramori I, Ohkubo H, Nakanishi S,. 1990. Cloning and expression of a cDNA encoding an endothelin receptor. Nature 348: 730-732. (Pubitemid 120015147)
2. Behfar A, Zingman LV, Hodgson DM, Rauzier JM, Kane GC, Terzic A, Puceat M,. 2002. Stem cell differentiation requires a paracrine pathway in the heart. FASEB J 16: 1558-1566.
3. Binetruy B, Heasley L, Bost F, Caron L, Aouadi M,. 2007. Concise review: Regulation of embryonic stem cell lineage commitment by mitogen-activated protein kinases. Stem Cells 25: 1090-1095.
4. Bogoyevitch MA, Glennon PE, Andersson MB, Clerk A, Lazou A, Marshall CJ, Parker PJ, Sugden PH,. 1994. Endothelin-1 and fibroblast growth factors stimulate the mitogen-activated protein kinase signaling cascade in cardiac myocytes. The potential role of the cascade in the integration of two signaling pathways leading to myocyte hypertrophy. J Biol Chem 269: 1110-1119.
5. Bongso A, Fong CY, Gauthaman K,. 2008. Taking stem cells to the clinic: Major challenges. J Cell Biochem 105: 1352-1360.
6. Brown CO III, Chi X, Garcia-Gras E, Shirai M, Feng XH, Schwartz RJ,. 2004. The cardiac determination factor, Nkx2-5, is activated by mutual cofactors GATA-4 and Smad1/4 via a novel upstream enhancer. J Biol Chem 279: 10659-10669.
7. Bruneau BG,. 2002. Transcriptional regulation of vertebrate cardiac morphogenesis. Circ Res 90: 509-519.
8. Cai J, Yi FF, Yang XC, Lin GS, Jiang H, Wang T, Xia Z,. 2007. Transplantation of embryonic stem cell-derived cardiomyocytes improves cardiac function in infarcted rat hearts. Cytotherapy 9: 283-291.
9. Chen K, Wu L, Wang ZZ,. 2008. Extrinsic regulation of cardiomyocyte differentiation of embryonic stem cells. J Cell Biochem 104: 119-128.
10. Choukroun G, Hajjar R, Kyriakis JM, Bonventre JV, Rosenzweig A, Force T,. 1998. Role of the stress-activated protein kinases in endothelin-induced cardiomyocyte hypertrophy. J Clin Invest 102: 1311-1320.
11. Dell'Era P, Ronca R, Coco L, Nicoli S, Metra M, Presta M,. 2003. Fibroblast growth factor receptor-1 is essential for in vitro cardiomyocyte development. Circ Res 93: 414-420.
12. Durocher D, Charron F, Warren R, Schwartz RJ, Nemer M,. 1997. The cardiac transcription factors Nkx2-and GATA-4 are mutual cofactors. EMBO J 16: 5687-5696.
13. Eriksson M, Leppa S,. 2002. Mitogen-activated protein kinases and activator protein 1 are required for proliferation and cardiomyocyte differentiation of P19 embryonal carcinoma cells. J Biol Chem 277: 15992-16001.
14. Gassanov N, Er F, Zagidullin N, Hoppe UC,. 2004. Endothelin induces differentiation of ANP-EGFP expressing embryonic stem cells towards a pacemaker phenotype. FASEB J 18: 1710-1712.
15. Gourdie RG, Wei Y, Kim D, Klatt SC, Mikawa T,. 1998. Endothelin-induced conversion of embryonic heart muscle cells into impulse-conducting Purkinje fibers. Proc Natl Acad Sci USA 95: 6815-6818.
16. Harris BS, Spruill L, Edmonson AM, Rackley MS, Benson DW, O'Brien TX, Gourdie RG,. 2006. Differentiation of cardiac Purkinje fibers requires precise spatiotemporal regulation of Nkx2-5 expression. Dev Dyn 235: 38-49.
17. Irukayama-Tomobe Y, Miyauchi T, Sakai S, Kasuya Y, Ogata T, Takanashi M, Iemitsu M, Sudo T, Goto K, Yamaguchi I,. 2004. Endothelin-1-induced cardiac hypertrophy is inhibited by activation of peroxisome proliferator-activated receptor-alpha partly via blockade of c-Jun NH2-terminal kinase pathway. Circulation 109: 904-910.
18. Kanzawa N, Poma CP, Takebayashi-Suzuki K, Diaz KG, Layliev J, Mikawa T,. 2002. Competency of embryonic cardiomyocytes to undergo Purkinje fiber differentiation is regulated by endothelin receptor expression. Development 129: 3185-3194.
19. Kehat I, Khimovich L, Caspi O, Gepstein A, Shofti R, Arbel G, Huber I, Satin J, Itskovitz-Eldor J, Gepstein L,. 2004. Electromechanical integration of cardiomyocytes derived from human embryonic stem cells. Nat Biotechnol 22: 1282-1289. (Pubitemid 39341201)
20. Kelley C, Blumberg H, Zon LI, Evans T,. 1993. GATA-4 is a novel transcription factor expressed in endocardium of the developing heart. Development 118: 817-827.
21. Kurihara Y, Kurihara H, Oda H, Maemura K, Nagai R, Ishikawa T, Yazaki Y,. 1995. Aortic arch malformations and ventricular septal defect in mice deficient in endothelin-1. J Clin Invest 96: 293-300.
22. Ladd AN, Yatskievych TA, Antin PB,. 1998. Regulation of avian cardiac myogenesis by activin/TGFbeta and bone morphogenetic proteins. Dev Biol 204: 407-419.
23. Linhares VL, Almeida NA, Menezes DC, Elliott DA, Lai D, Beyer EC, Campos de Carvalho AC, Costa MW,. 2004. Transcriptional regulation of the murine Connexin40 promoter by cardiac factors Nkx2-5, GATA4 and Tbx5. Cardiovasc Res 64: 402-411.
24. Lints TJ, Parsons LM, Hartley L, Lyons I, Harvey RP,. 1993. Nkx-2.5: A novel murine homeobox gene expressed in early heart progenitor cells and their myogenic descendants. Development 119: 419-431.
25. Lyons I, Parsons LM, Hartley L, Li R, Andrews JE, Robb L, Harvey RP,. 1995. Myogenic and morphogenetic defects in the heart tubes of murine embryos lacking the homeo box gene Nkx 2-5. Genes Dev 9: 1654-1666.
26. Maltsev VA, Rohwedel J, Hescheler J, Wobus AM,. 1993. Embryonic stem cells differentiate in vitro into cardiomyocytes representing sinusnodal, atrial and ventricular cell types. Mech Dev 44: 41-50.
27. Maltsev VA, Wobus AM, Rohwedel J, Bader M, Hescheler J,. 1994. Cardiomyocytes differentiated in vitro from embryonic stem cells developmentally express cardiac-specific genes and ionic currents. Circ Res 75: 233-244.
28. Molkentin JD, Kalvakolanu DV, Markham BE,. 1994. Transcription factor GATA-4 regulates cardiac muscle-specific expression of the alpha-myosin heavy-chain gene. Mol Cell Biol 14: 4947-4957.
29. Murry CE, Keller G,. 2008. Differentiation of embryonic stem cells to clinically relevant populations: Lessons from embryonic development. Cell 132: 661-680.
30. Naito AT, Shiojima I, Akazawa H, Hidaka K, Morisaki T, Kikuchi A, Komuro I,. 2006. Developmental stage-specific biphasic roles of Wnt/beta-catenin signaling in cardiomyogenesis and hematopoiesis. Proc Natl Acad Sci USA 103: 19812-19817.
31. Narita N, Bielinska M, Wilson DB,. 1997. Cardiomyocyte differentiation by GATA-4-deficient embryonic stem cells. Development 124: 3755-3764.
32. Patel R, Kos L,. 2005. Endothelin-1 and neuregulin-1 convert embryonic cardiomyocytes into cells of the conduction system in the mouse. Dev Dyn 233: 20-28.
33. Takebayashi-Suzuki K, Yanagisawa M, Gourdie RG, Kanzawa N, Mikawa T,. 2000. In vivo induction of cardiac Purkinje fiber differentiation by coexpression of preproendothelin-1 and endothelin converting enzyme-1. Development 127: 3523-3532.
34. Takebayashi-Suzuki K, Pauliks LB, Eltsefon Y, Mikawa T,. 2001. Purkinje fibers of the avian heart express a myogenic transcription factor program distinct from cardiac and skeletal muscle. Dev Biol 234: 390-401.
35. Ventura C, Maioli M,. 2000. Opioid peptide gene expression primes cardiogenesis in embryonal pluripotent stem cells. Circ Res 87: 189-194.
36. Wiese C, Nikolova T, Zahanich I, Sulzbacher S, Fuchs J, Yamanaka S, Graf E, Ravens U, Boheler KR, Wobus AM,. 2009. Differentiation induction of mouse embryonic stem cells into sinus node-like cells by suramin. Int J Cardiol. Epub ahead of print. DOI: 10.1016/j.ijcard.2009.08.021.
37. Wobus AM, Kaomei G, Shan J, Wellner MC, Rohwedel J, Ji G, Fleischmann B, Katus HA, Hescheler J, Franz WM,. 1997. Retinoic acid accelerates embryonic stem cell-derived cardiac differentiation and enhances development of ventricular cardiomyocytes. J Mol Cell Cardiol 29: 1525-1539.
38. Yanagisawa M, Kurihara H, Kimura S, Tomobe Y, Kobayashi M, Mitsui Y, Yazaki Y, Goto K, Masaki T,. 1988. A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature 332: 411-415.
39. Zaffran S, Frasch M,. 2002. Early signals in cardiac development. Circ Res 91: 457-469.