Relation of circulating oxidized LDL to obesity and insulin resistance in children

Pediatric Diabetes

Volumn 11, Issue 8, 2010, Pages 552-555

  Kelly, Aaron S ^a   Jacobs, David R ^b,c   Sinaiko, Alan R ^a   Moran, Antoinette ^a   Steffen, Lyn M ^b   Steinberger, Julia ^a  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

^c UNIVERSITY OF OSLO   (Norway)

Author keywords

Children; Insulin resistance; Obesity; Oxidized LDL

Indexed keywords

OXIDIZED LOW DENSITY LIPOPROTEIN;

ABDOMINAL SUBCUTANEOUS FAT; ADOLESCENT; ADULT; ARTICLE; BLOOD PRESSURE; BODY FAT DISTRIBUTION; BODY MASS; CHILD; CONTROLLED STUDY; FEMALE; HUMAN; INSULIN RESISTANCE; INTRAABDOMINAL FAT; LIPID BLOOD LEVEL; LIPOPROTEIN BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; OBESITY; OXIDATIVE STRESS; PRESCHOOL CHILD; PRIORITY JOURNAL; SCHOOL CHILD; WAIST CIRCUMFERENCE;

ADOLESCENT; BODY MASS INDEX; CARDIOVASCULAR DISEASES; CHILD; FEMALE; HUMANS; INSULIN RESISTANCE; INTRA-ABDOMINAL FAT; LIPIDS; LIPOPROTEINS, LDL; MALE; OBESITY; OXIDATIVE STRESS; RISK;

EID: 78649793474     PISSN: 1399543X     EISSN: 13995448     Source Type: Journal    
DOI: 10.1111/j.1399-5448.2009.00640.x     Document Type: Article

References (19)

1. Park K, Gross M, Lee DH et al. Oxidative stress and insulin resistance: the coronary artery risk development in young adults study. Diabetes Care 2009: 32: 1302-1307.
2. Yui S, Sasaki T, Miyazaki A, Horiuchi S, Yamazaki M. Induction of murine macrophage growth by modified LDLs. Arterioscler Thromb 1993: 13: 331-337.
3. Couillard C, Ruel G, Archer WR et al. Circulating levels of oxidative stress markers and endothelial adhesion molecules in men with abdominal obesity. J Clin Endocrinol Metab 2005: 90: 6454-6459.
4. Weinbrenner T, Schroder H, Escurriol V et al. Circulating oxidized LDL is associated with increased waist circumference independent of body mass index in men and women. Am J Clin Nutr 2006: 83: 30-35.
5. Ho RC, Davy K, Davy B, Melby CL. Whole-body insulin sensitivity, low-density lipoprotein (LDL) particle size, and oxidized LDL in overweight, nondiabetic men. Metabolism 2002: 51: 1478-1483.
6. Holvoet P, Kritchevsky SB, Tracy RP et al. The metabolic syndrome, circulating oxidized LDL, and risk of myocardial infarction in well-functioning elderly people in the health, aging, and body composition cohort. Diabetes 2004: 53: 1068-1073.
7. Holvoet P, Lee DH, Steffes M, Gross M, Jacobs DR Jr. Association between circulating oxidized low-density lipoprotein and incidence of the metabolic syndrome. JAMA 2008: 299: 2287-2293.
8. Lapointe A, Couillard C, Piche ME et al. Circulating oxidized LDL is associated with parameters of the metabolic syndrome in postmenopausal women. Atherosclerosis 2007: 191: 362-368.
9. Van Guilder GP, Hoetzer GL, Greiner JJ, Stauffer BL, Desouza CA. Influence of metabolic syndrome on biomarkers of oxidative stress and inflammation in obese adults. Obesity (Silver Spring) 2006: 14: 2127-2131.
10. Holvoet P, Vanhaecke J, Janssens S, Van de WF, Collen D. Oxidized LDL and malondialdehyde-modified LDL in patients with acute coronary syndromes and stable coronary artery disease. Circulation 1998: 98: 1487-1494.
11. Holvoet P, Mertens A, Verhamme P et al. Circulating oxidized LDL is a useful marker for identifying patients with coronary artery disease. Arterioscler Thromb Vasc Biol 2001: 21: 844-848.
12. Holvoet P, Jenny NS, Schreiner PJ, Tracy RP, Jacobs DR. The relationship between oxidized LDL and other cardiovascular risk factors and subclinical CVD in different ethnic groups: the Multi-Ethnic Study of Atherosclerosis (MESA). Atherosclerosis 2007: 194: 245-252.
13. Sinaiko AR, Jacobs DR Jr, Steinberger J et al. Insulin resistance syndrome in childhood: associations of the euglycemic insulin clamp and fasting insulin with fatness and other risk factors. J Pediatr 2001: 139: 700-707.
14. Moran A, Jacobs DR Jr, Steinberger J et al. Insulin resistance during puberty: results from clamp studies in 357 children. Diabetes 1999: 48: 2039-2044.
15. Jarvisalo MJ, Lehtimaki T, Raitakari OT. Determinants of arterial nitrate-mediated dilatation in children: role of oxidized low-density lipoprotein, endothelial function, and carotid intima-media thickness. Circulation 2004: 109: 2885-2889.
16. Stringer DM, Sellers EA, Burr LL, Taylor CG. Altered plasma adipokines and markers of oxidative stress suggest increased risk of cardiovascular disease in First Nation youth with obesity or type 2 diabetes mellitus. Pediatr Diabetes 2009: 10: 269-277.
17. Demirel F, Bideci A, Cinaz P et al. Serum leptin, oxidized low density lipoprotein and plasma asymmetric dimethylarginine levels and their relationship with dyslipidaemia in adolescent girls with polycystic ovary syndrome. Clin Endocrinol (Oxf) 2007: 67: 129-134.
18. Kelishadi R, Cook SR, Amra B, Adibi A. Factors associated with insulin resistance and non-alcoholic fatty liver disease among youths. Atherosclerosis 2009: 204: 538-543.
19. Itabe H, Ueda M. Measurement of plasma oxidized low-density lipoprotein and its clinical implications. J Atheroscler Thromb 2007: 14: 1-11.