Mannosylated solid lipid nanoparticles as vectors for site-specific delivery of an anti-cancer drug

Journal of Controlled Release

Volumn 148, Issue 3, 2010, Pages 359-367

  Jain, Ashay ^a   Agarwal, Abhinav ^a   Majumder, Saikat ^b   Lariya, Narendra ^a   Khaya, Anil ^a   Agrawal, Himanshu ^c   Majumdar, Subrata ^b   Agrawal, Govind P ^a  

^a DR H S GOUR UNIVERSITY   (India)

^b BOSE INSTITUTE   (India)

^c M S UNIVERSITY OF BARODA   (India)

Author keywords

Doxorubicin; Mannose; Solid lipid nanoparticles; Tumor targeting

Indexed keywords

A549 CELLS; ANTICANCER DRUG; BI-PHASIC; BIOACTIVES; BIODISTRIBUTIONS; CANCER CHEMOTHERAPY; CELLULAR UPTAKE; CYTOTOXIC; DOXORUBICIN; EX-VIVO; HALF LIVES; HEPATIC TISSUE; IN-VITRO; IN-VIVO; MANNOSE; MEAN RESIDENCE TIME; PHARMACOKINETIC STUDIES; POTENTIAL APPLICATIONS; PROLONGED RELEASE; RAPID RELEASE; SIDE EFFECT; SITE-SPECIFIC; SOLID LIPID NANOPARTICLES; TEM; TISSUE DISTRIBUTION PATTERNS; TUMOR CELLS; TUMOR SITE; TUMOR TARGETING;

BIOCHEMISTRY; CELL CULTURE; CHEMOTHERAPY; CYTOTOXICITY; DRUG DELIVERY; DRUG PRODUCTS; FOURIER TRANSFORM INFRARED SPECTROSCOPY; FOURIER TRANSFORMS; NANOPARTICLES; PHARMACOKINETICS; TRANSMISSION ELECTRON MICROSCOPY;

TUMORS;

DOXORUBICIN; MANNOSE; SOLID LIPID NANOPARTICLE;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CANCER CELL CULTURE; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; CYTOTOXICITY; DRUG BIOAVAILABILITY; DRUG CLEARANCE; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG DOSAGE FORM COMPARISON; DRUG ELIMINATION; DRUG FORMULATION; DRUG HALF LIFE; DRUG TISSUE LEVEL; DRUG UPTAKE; HEMOLYSIS; HUMAN; HUMAN CELL; LIVER TOXICITY; MALE; MAXIMUM PLASMA CONCENTRATION; MOUSE; NEPHROTOXICITY; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; TISSUE DISTRIBUTION; ZETA POTENTIAL;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; CELL LINE, TUMOR; CELL SURVIVAL; DOXORUBICIN; DRUG CARRIERS; HEMOLYSIS; HUMANS; KIDNEY; LIPIDS; LIVER; MALE; MANNOSE; MICE; MICE, INBRED BALB C; NANOPARTICLES; NEOPLASMS; PARTICLE SIZE;

EID: 78649786387     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2010.09.003     Document Type: Article

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