Macrophage inflammatory protein-1α induces osteoclast formation by activation of the MEK/ERK/c-Fos pathway and inhibition of the p38MAPK/IRF-3/IFN-β pathway

Journal of Cellular Biochemistry

Volumn 111, Issue 6, 2010, Pages 1661-1672

  Tsubaki, Masanobu ^a   Kato, Chisato ^a   Isono, Ai ^a   Kaneko, Junichi ^a   Isozaki, Misako ^a   Satou, Takao ^b   Itoh, Tatsuki ^b   Kidera, Yasuhiro ^a,c   Tanimori, Yoshihiro ^a,c   Yanae, Masashi ^a,b   Nishida, Shozo ^a  

^a KINKI UNIVERSITY   (Japan)

^b KINKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c KINDAI UNIVERSITY HOSPITAL   (Japan)

Author keywords

ERK1 2; IFN ; MIP 1 ; osteoclast; p38MAPK

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; BETA INTERFERON; INTERFERON REGULATORY FACTOR 3; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN C FOS;

ANIMAL CELL; ARTICLE; BONE ATROPHY; CLINICAL ASSESSMENT; DRUG ACTIVITY; DRUG MECHANISM; ENZYME INDUCTION; MACROPHAGE; MOUSE; MULTIPLE MYELOMA; NONHUMAN; OSTEOCLASTOGENESIS; OSTEOLYSIS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; BLOTTING, WESTERN; BUTADIENES; CELL LINE; CHEMOKINE CCL3; ENZYME INHIBITORS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; IMIDAZOLES; INTERFERON REGULATORY FACTOR-3; INTERFERON-BETA; MICE; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; NITRILES; OSTEOCLASTS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTO-ONCOGENE PROTEINS C-FOS; PYRIDINES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

EID: 78649766967     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.22907     Document Type: Article

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