Design of the Quality of Life in Motion (QLIM) study: A randomized controlled trial to evaluate the effectiveness and cost-effectiveness of a combined physical exercise and psychosocial training program to improve physical fitness in children with cancer

BMC Cancer

Volumn 10, Issue , 2010, Pages

  Braam, Katja I ^a   van Dijk, Elisabeth M ^a   Veening, Margreet A ^a   Bierings, Marc B ^b   Merks, Johannes H M ^c   Grootenhuis, Martha A ^c   Chinapaw, Mai J M ^a   Sinnema, Gerben ^b   Takken, Tim ^b   Huisman, Jaap ^a   Kaspers, Gertjan J L ^a   van Dulmen den Broeder, Eline ^a  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^c EMMA CHILDREN S HOSPITAL   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ADVERSE OUTCOME; ARTICLE; CHILD; CHILDHOOD CANCER; CLINICAL EFFECTIVENESS; CLINICAL EVALUATION; CLINICAL PROTOCOL; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; COST EFFECTIVENESS ANALYSIS; EXERCISE; EXERCISE INTENSITY; FEMALE; FITNESS; HUMAN; MALE; MULTICENTER STUDY; MUSCLE STRENGTH; PROCESS DESIGN; PROGRAM DEVELOPMENT; PSYCHOSOCIAL CARE; QUALITY OF LIFE; RANDOMIZED CONTROLLED TRIAL; SUPPORT GROUP; THERAPY EFFECT; TREATMENT DURATION; TREATMENT PLANNING; WELLBEING; ADOLESCENT; CONTROLLED STUDY; COST BENEFIT ANALYSIS; ECONOMICS; KINESIOTHERAPY; METHODOLOGY; NEOPLASM; PHYSIOLOGY; PSYCHOLOGICAL ASPECT; REGRESSION ANALYSIS; TREATMENT OUTCOME;

ADOLESCENT; CHILD; COST-BENEFIT ANALYSIS; EXERCISE; EXERCISE THERAPY; FEMALE; HUMANS; MALE; NEOPLASMS; PHYSICAL FITNESS; QUALITY OF LIFE; REGRESSION ANALYSIS; TREATMENT OUTCOME;

EID: 78649761706     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-10-624     Document Type: Article

References (42)

1. Geenen MM, Cardous-Ubbink MC, Kremer LC, van den Bos C, van der Pal HJ, Heinen RC, Jaspers MW, Koning CC, Oldenburger F, Langeveld NE, Hart AA, Bakker PJ, Caron HN, van Leeuwen FE. Medical assessment of adverse health outcomes in long-term survivors of childhood cancer. JAMA 2007, 297:2705-15. 10.1001/jama.297.24.2705, 17595271.
2. Warner JT, Bell W, Webb DK, Gregory JW. Daily energy expenditure and physical activity in survivors of childhood malignancy. Pediatr Res 1998, 43:607-13. 10.1203/00006450-199805000-00008, 9585006.
3. Van Brussel M, Takken T, Lucia A, van der Net J, Helders PJ. Is physical fitness decreased in survivors of childhood leukemia? A systematic review. Leukemia 2005, 19:13-7.
4. San Juan AF, Chamorro-Viña C, Maté-Muñoz JL, Fernández del Valle M, Cardona C, Hernández M, Madero L, Pérez M, Ramírez M, Lucia A. Functional capacity of children with leukemia. Int J Sports Med 2008, 29:163-7. 10.1055/s-2007-964908, 17879894.
5. Aznar S, Webster AL, San Juan AF, Chamorro-Viña C, Maté-Muñoz JL, Moral S, Pérez M, García-Castro J, Ramírez M, Madero L, Lucia A. Physical activity during treatment in children with leukemia: a pilot study. Appl Physiol Nutr Metab 2006, 31:407-13. 10.1139/H06-014, 16900230.
6. Van Brussel M, Takken T, van der Net J, Engelbert RH, Bierings M, Schoenmakers MA, Helders PJ. Physical function and fitness in long-term survivors of childhood leukaemia. Pediatr Rehabil 2006, 9:267-74.
7. Warner JT. Body composition, exercise and energy expenditure in survivors of acute lymphoblastic leukaemia. Pediatr Blood Cancer 2008, 50:456-61. 10.1002/pbc.21411, 18064643.
8. Florin TA, Fryer GE, Miyoshi T, Weitzman M, Mertens AC, Hudson MM, Sklar CA, Emmons K, Hinkle A, Whitton J, Stovall M, Robison LL, Oeffinger KC. Physical inactivity in adult survivors of childhood acute lymphoblastic leukemia: a report from the childhood cancer survivor study. Cancer Epidemiol Biomarkers Prev 2007, 16:1356-63. 10.1158/1055-9965.EPI-07-0048, 17627001.
9. Brouwer CA, Gietema JA, Kamps WA, de Vries EG, Postma A. Changes in body composition after childhood cancer treatment: impact on future health status-a review. Crit Rev Oncol Hematol 2007, 63:32-46. 10.1016/j.critrevonc.2007.01.007, 17344062.
10. Tillmann V, Darlington AS, Eiser C, Bishop NJ, Davies HA. Male sex and low physical activity are associated with reduced spine bone mineral density in survivors of childhood acute lymphoblastic leukemia. J Bone Miner Res 2002, 17:1073-80. 10.1359/jbmr.2002.17.6.1073, 12054163.
11. Eiser C, Vance YH, Horne B, Glaser A, Galvin H. The value of the PedsQLTM in assessing quality of life in survivors of childhood cancer. Child Care Health Dev 2003, 29:95-102. 10.1046/j.1365-2214.2003.00318.x, 12603354.
12. Odame I, Duckworth J, Talsma D, Beaumont L, Furlong W, Webber C, Barr R. Osteopenia physical activity and health-related quality of life in survivors of brain tumors treated in childhood. Pediatr Blood Cancer 2006, 46:357-62. 10.1002/pbc.20512, 16035080.
13. Meeske KA, Siegel SE, Globe DR, Mack WJ, Bernstein L. Prevalence and correlates of fatigue in long-term survivors of childhood leukemia. J Clin Oncol 2005, 23:5501-10. 10.1200/JCO.2005.03.210, 16110010.
14. Varni JW, Limbers CA, Burwinkle TM. Impaired health-related quality of life in children and adolescents with chronic conditions: a comparative analysis of 10 disease clusters and 33 disease categories/severities utilizing the PedsQL 4.0 Generic Core Scales. Health Qual Life Outcomes 2007, 5:43. 10.1186/1477-7525-5-43, 1964786, 17634123.
15. May AM, Van Weert E, Korstjens I, Hoekstra-Weebers JE, Van Der Schans CP, Zonderland ML, Mesters I, Van Den Borne B, Ros WD. Improved physical fitness of cancer survivors: a randomised controlled trial comparing physical training with physical and cognitive-behavioural training. Acta Oncol 2008, 47:825-34. 10.1080/02841860701666063, 17917819.
16. Courneya KS, Sellar CM, Stevinson C, McNeely ML, Peddle CJ, Friedenreich CM, Tankel K, Basi S, Chua N, Mazurek A, Reiman T. Randomized controlled trial of the effects of aerobic exercise on physical functioning and quality of life in lymphoma patients. J Clin Oncol 2009, 27:4605-12. 10.1200/JCO.2008.20.0634, 19687337.
17. Weaver IC. Shaping adult phenotypes through early life environments. Birth Defects Res C Embryo Today 2009, 87:314-26. 10.1002/bdrc.20164, 19960543.
18. Herman KM, Hopman WM, Craig CL. Are youth BMI and physical activity associated with better or worse than expected health-related quality of life in adulthood?. The Physical Activity Longitudinal Study. Qual Life Res 2010, 19:339-49.
19. Winter C, Müller C, Brandes M, Brinkmann A, Hoffmann C, Hardes J, Gosheger G, Boos J, Rosenbaum D. Level of activity in children undergoing cancer treatment. Pediatr Blood Cancer 2009, 53:438-43. 10.1002/pbc.22055, 19415742.
20. Ness KK, Mertens AC, Hudson MM, Wall MM, Leisenring WM, Oeffinger KC, Sklar CA, Robison LL, Gurney JG. Limitations on physical performance and daily activities among long-term survivors of childhood cancer. Ann Intern Med 2005, 143:639-47.
21. San Juan AF, Fleck SJ, Chamorro-Viña C, Maté-Muñoz JL, Moral S, Pérez M, Cardona C, Del Valle MF, Hernández M, Ramírez M, Madero L, Lucia A. Effects of an intrahospital exercise program intervention for children with leukemia. Med Sci Sports Exerc 2007, 39:13-21. 10.1249/01.mss.0000240326.54147.fc, 17218878.
22. Hartman A, te Winkel ML, van Beek RD, de Muinck Keizer-Schrama SM, Kemper HC, Hop WC, van den Heuvel-Eibrink MM, Pieters R. A randomized trial investigating an exercise program to prevent reduction of bone mineral density and impairment of motor performance during treatment for childhood acute lymphoblastic leukemia. Pediatr Blood Cancer 2009, 53:64-71. 10.1002/pbc.21942, 19283791.
23. Marchese VG, Chiarello LA, Lange BJ. Effects of physical therapy intervention for children with acute lymphoblastic leukemia. Pediatr Blood Cancer 2004, 42:127-133. 10.1002/pbc.10481, 14752875.
24. Moyer-Mileur LJ, Ransdell L, Bruggers CS. Fitness of children with standard-risk acute lymphoblastic leukemia during maintenance therapy: response to a home-based exercise and nutrition program. J Pediatr Hematol Oncol 2009, 31:259-266. 10.1097/MPH.0b013e3181978fd4, 19346877.
25. Dimeo FC, Stieglitz RD, Novelli-Fischer U, Fetscher S, Keul J. Effects of physical activity on the fatigue and psychologic status of cancer patients during chemotherapy. Cancer 1999, 85:2273-2277. 10.1002/(SICI)1097-0142(19990515)85:10<2273::AID-CNCR24>3.0.CO;2-B, 10326708.
26. Coleman EA, Coon S, Hall-Barrow J, Richards K, Gaylor D, Stewart B. Feasibility of exercise during treatment for multiple myeloma. Cancer Nurs 2003, 26:410-9. 10.1097/00002820-200310000-00012, 14710804.
27. Takken T, van der Torre P, Zwerink M, Hulzebos EH, Bierings M, Helders PJM, van der Net JJ. Development, feasibility and efficacy of a community-based exercise training program in pediatric cancer survivors. Psychooncology 2009, 18:440-448. 10.1002/pon.1484, 19242926.
28. Chinapaw MJ, Buffart LM, van Mechelen W, Schep G, Aaronson NK, van Harten WH, Stuiver M, Kersten MJ, Nollet F, Kaspers GJL, et al. Alpe d'HuZes Cancer Rehabilitation (A-CaRe) research. Design of four randomized controlled exercise trials in cancer patients and survivors. BMC Cancer
29. Bradley J, Howard J, Wallace E, Elborn S. Validity of a modified shuttle test in adult cystic fibrosis. Thorax. 1999, 54:437-439. 1763768, 10212110.
30. Verschuren O, Takken T, Ketelaar M, Gorter JW, Helders PJ. Reliability for Running Tests for Measuring Agility and Anaerobic Muscle Power in Children and Adolescents with Cerebal Palsy. Pediatr Phys Ther 2007, 19:108-115. 10.1097/pep.0b013e318036bfce, 17505287.
31. Royal Canadian Air Force Physical Fitness: 5BX The 11 minute exercise plan for men, XBX the 12 minute exercise plan for women 1964, London: Penguin books Ltd, Royal Canadian Air Force.
32. Varni JW, Burwinkle TM, Katz ER, Meeske K, Dickinson P. The PedsQL™ in pediatric cancer. Reliability and validity of the pediatric quality of life inventory™ Genetic Core Scales, Multidimensional Fatigue Scale, and Cancer Module. Cancer 2002, 94:2090-2106. 10.1002/cncr.10428, 11932914.
33. Veerman JW, Straathof MAE, Treffers DA, van den Bergh BRH, ten Brink LT. De Competentiebelevingsschaal voor Kinderen (CBSK) 2004, Amsterdam: Harcourt Test Publishers.
34. Finch AJ, Saylor CF, Edwards GL, McIntosh JA. Children's Depression Inventory: Reliability Over Repeated Administrations. J Clin Child Adolesc Psychol 1987, 16:339-341.
35. Treffers DA, Goedhardt AW, Veerman JW, van den Bergh BRH, Ackaert L, de Rycke L. Handleiding Competentie Belevingsschaal voor Adolescenten 2002, Lisse: Swets Test Publishers.
36. Verhulst FC, Koot JM, Akkerhuis GW, Veerman JW. Praktische handleiding voor de CBCL (Child behavior checklist) 1990, Assen/Maastricht: Van Gorcum.
37. De Backer IC, Schep G, Hoogeveen A, Vreugdenhil G, Kester AD, Van Breda E. Exercise testing and training in a cancer rehabilitation program: the advantage of the steep ramp test. Arch Phys Med Rehabil 2007, 88:610-616. 10.1016/j.apmr.2007.02.013, 17466730.
38. Godfrey S. Exercise testing in children 1974, London: W.B. Saunders Company Ltd.
39. Liistro G, Vanwelde C, Vincken W, Vandevoorde J, Verleden G, Buffels J, . COPD Advisory Board Technical and functional assessment of 10 office spirometers: A multicenter comparative study. Chest 2006, 130:657-665. 10.1378/chest.130.3.657, 16963659, COPD Advisory Board.
40. Bäckman E. Methods for measurement of muscle function. Methodological aspects, reference values for children, and clinical applications. Scand J Rehabil Med Suppl 1988, 20:9-95.
41. Sloan C. Review of the reliability and validity of myometry with children. Phys Occup Ther Pediatr 2002, 22:79-93.
42. Altman DG. Practical statistics for medical research 1999, Florida: CRC Press LLC.