Visual responses in mice lacking critical components of all known retinal phototransduction cascades

PLoS ONE

Volumn 5, Issue 11, 2010, Pages

  Allen, Annette E ^a   Cameron, Morven A ^a,c   Brown, Timothy M ^a   Vugler, Anthony A ^b   Lucas, Robert J ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY OF SYDNEY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; ALPHA TRANSDUCIN; ALPHA3 CYCLIC NUCLEOTIDE GATED CHANNEL; CYCLIC NUCLEOTIDE GATED CHANNEL; MELANOPSIN; OPSIN; TRANSDUCIN; UNCLASSIFIED DRUG; 1 (6 ((3 METHOXYESTRA 1,3,5(10) TRIEN 17 YL)AMINO)HEXYL) 1H PYRROLE 2,5 DIONE; 1-(6-((3-METHOXYESTRA-1,3,5(10)-TRIEN-17-YL)AMINO)HEXYL)-1H-PYRROLE-2,5-DIONE; 2 PYRROLIDONE DERIVATIVE; CNGA3 PROTEIN, MOUSE; ESTRANE DERIVATIVE; GNAT1 PROTEIN, MOUSE; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; PHOSPHODIESTERASE INHIBITOR; SCOTOPSIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BLINDNESS; CONTROLLED STUDY; ELECTRORETINOGRAPHY; EVOKED VISUAL RESPONSE; FEMALE; GENE DISRUPTION; GENE SILENCING; IMMUNOHISTOCHEMISTRY; KNOCKOUT GENE; LATERAL GENICULATE NUCLEUS; LIGHT ABSORPTION; LIGHT ADAPTATION; MALE; MISSENSE MUTATION; MOUSE; NONHUMAN; PHOTORECEPTOR; PHOTOTRANSDUCTION; RETINA GANGLION CELL; RETINA ROD; SPECTRAL SENSITIVITY; STIMULUS RESPONSE; THALAMOCORTICAL TRACT; VISUAL CORTEX; ANIMAL; DRUG EFFECT; ENZYMOLOGY; GENETICS; GENICULATE BODY; METABOLISM; MOUSE MUTANT; PHYSIOLOGY; RETINA; VISION; VISUAL ADAPTATION;

MAMMALIA; MUS;

ADAPTATION, OCULAR; ANIMALS; CYCLIC NUCLEOTIDE-GATED CATION CHANNELS; ELECTRORETINOGRAPHY; ESTRENES; GENICULATE BODIES; GTP-BINDING PROTEIN ALPHA SUBUNITS; LIGHT SIGNAL TRANSDUCTION; MALE; MICE; MICE, KNOCKOUT; PHOSPHODIESTERASE INHIBITORS; PYRROLIDINONES; RETINA; RETINAL ROD PHOTORECEPTOR CELLS; ROD OPSINS; TRANSDUCIN; VISUAL CORTEX; VISUAL PERCEPTION;

EID: 78649743554     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0015063     Document Type: Article

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