-
1
-
-
41049106214
-
Non-motor symptoms in Parkinson's disease
-
10.1111/j.1468-1331.2008.02056.x. 18353132
-
Non-motor symptoms in Parkinson's disease. W Poewe, Eur J Neurol 2008 15 Suppl 1 14 20 10.1111/j.1468-1331.2008.02056.x 18353132
-
(2008)
Eur J Neurol
, vol.15
, Issue.SUPPL. 1
, pp. 14-20
-
-
Poewe, W.1
-
2
-
-
0037335814
-
Prevalence and characteristics of dementia in Parkinson disease: An 8-year prospective study
-
10.1001/archneur.60.3.387. 12633150
-
Prevalence and characteristics of dementia in Parkinson disease: an 8-year prospective study. D Aarsland K Andersen JP Larsen A Lolk P Kragh-Sorensen, Arch Neurol 2003 60 3 387 392 10.1001/archneur.60.3.387 12633150
-
(2003)
Arch Neurol
, vol.60
, Issue.3
, pp. 387-392
-
-
Aarsland, D.1
Andersen, K.2
Larsen, J.P.3
Lolk, A.4
Kragh-Sorensen, P.5
-
3
-
-
33144489150
-
Diagnosis and management of dementia with Lewy bodies: Third report of the DLB Consortium
-
10.1212/01.wnl.0000187889.17253.b1. 16237129
-
Diagnosis and management of dementia with Lewy bodies: third report of the DLB Consortium. IG McKeith DW Dickson J Lowe M Emre JT O'Brien H Feldman J Cummings JE Duda C Lippa EK Perry,, et al. Neurology 2005 65 12 1863 1872 10.1212/01.wnl.0000187889.17253.b1 16237129
-
(2005)
Neurology
, vol.65
, Issue.12
, pp. 1863-1872
-
-
McKeith, I.G.1
Dickson, D.W.2
Lowe, J.3
Emre, M.4
O'Brien, J.T.5
Feldman, H.6
Cummings, J.7
Duda, J.E.8
Lippa, C.9
Perry, E.K.10
-
4
-
-
27544470486
-
Snaring the function of alpha-synuclein
-
10.1016/j.cell.2005.10.017. 16269324
-
Snaring the function of alpha-synuclein. NM Bonini BI Giasson, Cell 2005 123 3 359 361 10.1016/j.cell.2005.10.017 16269324
-
(2005)
Cell
, vol.123
, Issue.3
, pp. 359-361
-
-
Bonini, N.M.1
Giasson, B.I.2
-
5
-
-
0037109727
-
Synaptic vesicle depletion correlates with attenuated synaptic responses to prolonged repetitive stimulation in mice lacking alpha-synuclein
-
12388586
-
Synaptic vesicle depletion correlates with attenuated synaptic responses to prolonged repetitive stimulation in mice lacking alpha-synuclein. DE Cabin K Shimazu D Murphy NB Cole W Gottschalk KL McIlwain B Orrison A Chen CE Ellis R Paylor,, et al. J Neurosci 2002 22 20 8797 8807 12388586
-
(2002)
J Neurosci
, vol.22
, Issue.20
, pp. 8797-8807
-
-
Cabin, D.E.1
Shimazu, K.2
Murphy, D.3
Cole, N.B.4
Gottschalk, W.5
McIlwain, K.L.6
Orrison, B.7
Chen, A.8
Ellis, C.E.9
Paylor, R.10
-
6
-
-
0032102455
-
The synucleins: A family of proteins involved in synaptic function, plasticity, neurodegeneration and disease
-
10.1016/S0166-2236(97)01213-7. 9641537
-
The synucleins: a family of proteins involved in synaptic function, plasticity, neurodegeneration and disease. DF Clayton JM George, Trends Neurosci 1998 21 6 249 254 10.1016/S0166-2236(97)01213-7 9641537
-
(1998)
Trends Neurosci
, vol.21
, Issue.6
, pp. 249-254
-
-
Clayton, D.F.1
George, J.M.2
-
7
-
-
61449084604
-
Central role of alpha-synuclein oligomers in neurodegeneration in Parkinson disease
-
10.1001/archneur.65.12.1577. 19064744
-
Central role of alpha-synuclein oligomers in neurodegeneration in Parkinson disease. AG Kazantsev AM Kolchinsky, Arch Neurol 2008 65 12 1577 1581 10.1001/archneur.65.12.1577 19064744
-
(2008)
Arch Neurol
, vol.65
, Issue.12
, pp. 1577-1581
-
-
Kazantsev, A.G.1
Kolchinsky, A.M.2
-
8
-
-
33846997878
-
Presynaptic -Synuclein Aggregates, Not Lewy Bodies, Cause Neurodegeneration in Dementia with Lewy Bodies
-
10.1523/JNEUROSCI.4564-06.2007. 17287515
-
Presynaptic -Synuclein Aggregates, Not Lewy Bodies, Cause Neurodegeneration in Dementia with Lewy Bodies. ML Kramer WJ Schulz-Schaeffer, J Neurosci 2007 27 6 1405 1410 10.1523/JNEUROSCI.4564-06.2007 17287515
-
(2007)
J Neurosci
, vol.27
, Issue.6
, pp. 1405-1410
-
-
Kramer, M.L.1
Schulz-Schaeffer, W.J.2
-
9
-
-
33749240943
-
Mechanisms of Parkinson's Disease Linked to Pathological [alpha]-Synuclein: New Targets for Drug Discovery
-
10.1016/j.neuron.2006.09.026. 17015225
-
Mechanisms of Parkinson's Disease Linked to Pathological [alpha]-Synuclein: New Targets for Drug Discovery. VMY Lee JQ Trojanowski, Neuron 2006 52 1 33 38 10.1016/j.neuron.2006.09.026 17015225
-
(2006)
Neuron
, vol.52
, Issue.1
, pp. 33-38
-
-
Lee, V.M.Y.1
Trojanowski, J.Q.2
-
10
-
-
69149089854
-
Inclusion formation and neuronal cell death through neuron-to-neuron transmission of -synuclein
-
10.1073/pnas.0903691106. 19651612
-
Inclusion formation and neuronal cell death through neuron-to-neuron transmission of -synuclein. P Desplats H-J Lee E-J Bae C Patrick E Rockenstein L Crews B Spencer E Masliah S-J Lee, Proc Natl Acad Sci USA 2009 106 31 13010 13015 10.1073/pnas.0903691106 19651612
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, Issue.31
, pp. 13010-13015
-
-
Desplats, P.1
Lee, H.-J.2
Bae, E.-J.3
Patrick, C.4
Rockenstein, E.5
Crews, L.6
Spencer, B.7
Masliah, E.8
Lee, S.-J.9
-
11
-
-
77949848854
-
Prion-like transmission of protein aggregates in neurodegenerative diseases
-
10.1038/nrm2873. 20308987
-
Prion-like transmission of protein aggregates in neurodegenerative diseases. P Brundin R Melki R Kopito, Nat Rev Mol Cell Biol 2010 11 4 301 307 10.1038/nrm2873 20308987
-
(2010)
Nat Rev Mol Cell Biol
, vol.11
, Issue.4
, pp. 301-307
-
-
Brundin, P.1
Melki, R.2
Kopito, R.3
-
12
-
-
0037333666
-
Staging of brain pathology related to sporadic Parkinson's disease
-
10.1016/S0197-4580(02)00065-9. 12498954
-
Staging of brain pathology related to sporadic Parkinson's disease. H Braak K Del Tredici U Rub RA de Vos EN Jansen Steur E Braak, Neurobiol Aging 2003 24 2 197 211 10.1016/S0197-4580(02)00065-9 12498954
-
(2003)
Neurobiol Aging
, vol.24
, Issue.2
, pp. 197-211
-
-
Braak, H.1
Del Tredici, K.2
Rub, U.3
De Vos, R.A.4
Jansen Steur, E.N.5
Braak, E.6
-
13
-
-
0033539664
-
Axon pathology in Parkinson's disease and Lewy body dementia hippocampus contains alpha-, beta-, and gamma-synuclein
-
10.1073/pnas.96.23.13450. 10557341
-
Axon pathology in Parkinson's disease and Lewy body dementia hippocampus contains alpha-, beta-, and gamma-synuclein. JE Galvin K Uryu VM Lee JQ Trojanowski, Proc Natl Acad Sci USA 1999 96 23 13450 13455 10.1073/pnas.96.23. 13450 10557341
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, Issue.23
, pp. 13450-13455
-
-
Galvin, J.E.1
Uryu, K.2
Lee, V.M.3
Trojanowski, J.Q.4
-
14
-
-
63849332293
-
Dynamic changes in presynaptic and axonal transport proteins combined with striatal neuroinflammation precede dopaminergic neuronal loss in a rat model of AAV alpha-synucleinopathy
-
10.1523/JNEUROSCI.5427-08.2009. 19295143
-
Dynamic changes in presynaptic and axonal transport proteins combined with striatal neuroinflammation precede dopaminergic neuronal loss in a rat model of AAV alpha-synucleinopathy. CY Chung JB Koprich H Siddiqi O Isacson, J Neurosci 2009 29 11 3365 3373 10.1523/JNEUROSCI.5427-08.2009 19295143
-
(2009)
J Neurosci
, vol.29
, Issue.11
, pp. 3365-3373
-
-
Chung, C.Y.1
Koprich, J.B.2
Siddiqi, H.3
Isacson, O.4
-
15
-
-
77949895956
-
Polyunsaturated fatty acids protect against prion-mediated synapse damage in vitro
-
10.1007/s12640-009-9093-2. 19644728
-
Polyunsaturated fatty acids protect against prion-mediated synapse damage in vitro. C Bate M Tayebi M Salmona L Diomede A Williams, Neurotox Res 2010 17 3 203 214 10.1007/s12640-009-9093-2 19644728
-
(2010)
Neurotox Res
, vol.17
, Issue.3
, pp. 203-214
-
-
Bate, C.1
Tayebi, M.2
Salmona, M.3
Diomede, L.4
Williams, A.5
-
16
-
-
0027758904
-
Synaptic vesicle proteins and regulated exocytosis
-
Synaptic vesicle proteins and regulated exocytosis. LA Elferink RH Scheller, J Cell Sci 1993 17 75 79
-
(1993)
J Cell Sci
, vol.17
, pp. 75-79
-
-
Elferink, L.A.1
Scheller, R.H.2
-
17
-
-
0034705044
-
Synaptophysin regulates clathrin-independent endocytosis of synaptic vesicles
-
10.1073/pnas.97.11.6120. 10823955
-
Synaptophysin regulates clathrin-independent endocytosis of synaptic vesicles. C Daly M Sugimori JE Moreira EB Ziff R Llinas, Proc Natl Acad Sci USA 2000 97 11 6120 6125 10.1073/pnas.97.11.6120 10823955
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, Issue.11
, pp. 6120-6125
-
-
Daly, C.1
Sugimori, M.2
Moreira, J.E.3
Ziff, E.B.4
Llinas, R.5
-
18
-
-
17844378691
-
Differential loss of synaptic proteins in Alzheimer's disease: Implications for synaptic dysfunction
-
15851848
-
Differential loss of synaptic proteins in Alzheimer's disease: implications for synaptic dysfunction. PH Reddy G Mani BS Park J Jacques G Murdoch W Whetsell Jr. J Kaye M Manczak, J Alzheimers Dis 2005 7 2 103 117 15851848
-
(2005)
J Alzheimers Dis
, vol.7
, Issue.2
, pp. 103-117
-
-
Reddy, P.H.1
Mani, G.2
Park, B.S.3
Jacques, J.4
Murdoch, G.5
Whetsell Jr., W.6
Kaye, J.7
Manczak, M.8
-
19
-
-
33746752209
-
Differential expression of synaptic proteins in the frontal and temporal cortex of elderly subjects with mild cognitive impairment
-
10.1097/00005072-200606000-00007. 16783169
-
Differential expression of synaptic proteins in the frontal and temporal cortex of elderly subjects with mild cognitive impairment. SE Counts M Nadeem SP Lad J Wuu EJ Mufson, J Neuropath Exp Neurol 2006 65 6 592 601 10.1097/00005072-200606000-00007 16783169
-
(2006)
J Neuropath Exp Neurol
, vol.65
, Issue.6
, pp. 592-601
-
-
Counts, S.E.1
Nadeem, M.2
Lad, S.P.3
Wuu, J.4
Mufson, E.J.5
-
20
-
-
0026032039
-
Cortical and subcortical patterns of synaptophysinlike immunoreactivity in Alzheimer's disease
-
1899001
-
Cortical and subcortical patterns of synaptophysinlike immunoreactivity in Alzheimer's disease. E Masliah RD Terry M Alford R DeTeresa LA Hansen, Am J Path 1991 138 1 235 246 1899001
-
(1991)
Am J Path
, vol.138
, Issue.1
, pp. 235-246
-
-
Masliah, E.1
Terry, R.D.2
Alford, M.3
Deteresa, R.4
Hansen, L.A.5
-
21
-
-
77957261220
-
2and Synapse Degeneration
-
20634578
-
2and Synapse Degeneration. C Bate A Williams, J Alzheimers Dis 2010 21 3 985 993 20634578
-
(2010)
J Alzheimers Dis
, vol.21
, Issue.3
, pp. 985-993
-
-
Bate, C.1
Williams, A.2
-
22
-
-
0035950270
-
-Synuclein inhibits alpha-synuclein aggregation: A possible role as an anti-parkinsonian factor
-
10.1016/S0896-6273(01)00462-7. 11683992
-
-Synuclein inhibits alpha-synuclein aggregation: a possible role as an anti-parkinsonian factor. M Hashimoto E Rockenstein M Mante M Mallory E Masliah, Neuron 2001 32 2 213 223 10.1016/S0896-6273(01)00462-7 11683992
-
(2001)
Neuron
, vol.32
, Issue.2
, pp. 213-223
-
-
Hashimoto, M.1
Rockenstein, E.2
Mante, M.3
Mallory, M.4
Masliah, E.5
-
23
-
-
0037426346
-
Beta-synuclein inhibits formation of alpha-synuclein protofibrils: A possible therapeutic strategy against Parkinson's disease
-
10.1021/bi020604a. 12667059
-
Beta-synuclein inhibits formation of alpha-synuclein protofibrils: a possible therapeutic strategy against Parkinson's disease. JY Park PT Lansbury Jr, Biochemistry 2003 42 13 3696 3700 10.1021/bi020604a 12667059
-
(2003)
Biochemistry
, vol.42
, Issue.13
, pp. 3696-3700
-
-
Park, J.Y.1
Lansbury Jr., P.T.2
-
24
-
-
0033623415
-
A-Generating Enzymes: Recent Advances in and -Secretase Research
-
10.1016/S0896-6273(00)00051-9. 11055423
-
A-Generating Enzymes: Recent Advances in and -Secretase Research. R Vassar M Citron, Neuron 2000 27 3 419 422 10.1016/S0896-6273(00)00051-9 11055423
-
(2000)
Neuron
, vol.27
, Issue.3
, pp. 419-422
-
-
Vassar, R.1
Citron, M.2
-
25
-
-
0037135111
-
The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
-
10.1126/science.1072994. 12130773
-
The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. J Hardy DJ Selkoe, Science 2002 297 5580 353 356 10.1126/science.1072994 12130773
-
(2002)
Science
, vol.297
, Issue.5580
, pp. 353-356
-
-
Hardy, J.1
Selkoe, D.J.2
-
26
-
-
64149132721
-
Amyloid beta-protein toxicity and the pathogenesis of Alzheimer disease
-
Amyloid beta-protein toxicity and the pathogenesis of Alzheimer disease. BA Yankner T Lu, JBiolChem 2009 284 8 4755 4759
-
(2009)
JBiolChem
, vol.284
, Issue.8
, pp. 4755-4759
-
-
Yankner, B.A.1
Lu, T.2
-
27
-
-
52349111812
-
Mechanisms of Hybrid Oligomer Formation in the Pathogenesis of Combined Alzheimer's and Parkinson's Diseases
-
10.1371/journal.pone.0003135. 18769546
-
Mechanisms of Hybrid Oligomer Formation in the Pathogenesis of Combined Alzheimer's and Parkinson's Diseases. IF Tsigelny L Crews P Desplats GM Shaked Y Sharikov H Mizuno B Spencer E Rockenstein M Trejo O Platoshyn,, et al. PLoS ONE 2008 3 9 3135 10.1371/journal.pone.0003135 18769546
-
(2008)
PLoS ONE
, vol.3
, Issue.9
, pp. 53135
-
-
Tsigelny, I.F.1
Crews, L.2
Desplats, P.3
Shaked, G.M.4
Sharikov, Y.5
Mizuno, H.6
Spencer, B.7
Rockenstein, E.8
Trejo, M.9
Platoshyn, O.10
-
28
-
-
33748584602
-
Interaction between A Peptide and Synuclein: Molecular Mechanisms in Overlapping Pathology of Alzheimer's and Parkinson's in Dementia with Lewy Body Disease
-
10.1007/s11064-006-9140-9. 16947080
-
Interaction between A Peptide and Synuclein: Molecular Mechanisms in Overlapping Pathology of Alzheimer's and Parkinson's in Dementia with Lewy Body Disease. P Mandal J Pettegrew E Masliah R Hamilton R Mandal, Neurochem Res 2006 31 9 1153 1162 10.1007/s11064-006-9140-9 16947080
-
(2006)
Neurochem Res
, vol.31
, Issue.9
, pp. 1153-1162
-
-
Mandal, P.1
Pettegrew, J.2
Masliah, E.3
Hamilton, R.4
Mandal, R.5
-
29
-
-
0030293676
-
1-42/1-40ratio in vitro and in vivo
-
10.1016/S0896-6273(00)80230-5. 8938131
-
1-42/1-40ratio in vitro and in vivo. DR Borchelt G Thinakaran CB Eckman MK Lee F Davenport T Ratovitsky CM Prada G Kim S Seekins D Yager,, et al. Neuron 1996 17 5 1005 1013 10.1016/S0896-6273(00)80230-5 8938131
-
(1996)
Neuron
, vol.17
, Issue.5
, pp. 1005-1013
-
-
Borchelt, D.R.1
Thinakaran, G.2
Eckman, C.B.3
Lee, M.K.4
Davenport, F.5
Ratovitsky, T.6
Prada, C.M.7
Kim, G.8
Seekins, S.9
Yager, D.10
-
30
-
-
0028276801
-
Evidence that production and release of amyloid -protein involves the endocytic pathway
-
Evidence that production and release of amyloid -protein involves the endocytic pathway. EH Koo SL Squazzo, JBiolChem 1994 269 26 17386 17389
-
(1994)
JBiolChem
, vol.269
, Issue.26
, pp. 17386-17389
-
-
Koo, E.H.1
Squazzo, S.L.2
-
31
-
-
0028952749
-
Aggregation of secreted amyloid -protein into sodium dodecyl sulfate-stable oligomers in cell culture
-
Aggregation of secreted amyloid -protein into sodium dodecyl sulfate-stable oligomers in cell culture. MB Podlisny BL Ostaszewski SL Squazzo EH Koo RE Rydell DB Teplow DJ Selkoe, JBiolChem 1995 270 16 9564 9570
-
(1995)
JBiolChem
, vol.270
, Issue.16
, pp. 9564-9570
-
-
Podlisny, M.B.1
Ostaszewski, B.L.2
Squazzo, S.L.3
Koo, E.H.4
Rydell, R.E.5
Teplow, D.B.6
Selkoe, D.J.7
-
32
-
-
0034016049
-
Synapse loss associated with abnormal PrP precedes neuronal degeneration in the scrapie-infected murine hippocampus
-
DOI 10.1046/j.1365-2990.2000.00216.x
-
Synapse loss associated with abnormal PrP precedes neuronal degeneration in the scrapie-infected murine hippocampus. M Jeffrey WG Halliday J Bell AR Johnston NK MacLeod C Ingham AR Sayers DA Brown JR Fraser, Neuropath Appl Neurobiol 2000 26 1 41 54 10.1046/j.1365-2990.2000.00216.x (Pubitemid 30145305)
-
(2000)
Neuropathology and Applied Neurobiology
, vol.26
, Issue.1
, pp. 41-54
-
-
Jeffrey, M.1
Halliday, W.G.2
Bell, J.3
Johnston, A.R.4
Macleod, N.K.5
Ingham, C.6
Sayers, A.R.7
Brown, D.A.8
Fraser, J.R.9
-
33
-
-
0042734442
-
Synaptic pathology and cell death in the cerebellum in Creutzfeldt-Jakob disease
-
10.1080/14734220260418448. 12879983
-
Synaptic pathology and cell death in the cerebellum in Creutzfeldt-Jakob disease. I Ferrer, Cerebellum 2002 1 3 213 222 10.1080/14734220260418448 12879983
-
(2002)
Cerebellum
, vol.1
, Issue.3
, pp. 213-222
-
-
Ferrer, I.1
-
34
-
-
57549098245
-
Beta-Synuclein occurs in vivo in lipid-associated oligomers and forms hetero-oligomers with alpha-synuclein
-
10.1111/j.1471-4159.2008.05776.x. 19012742
-
beta-Synuclein occurs in vivo in lipid-associated oligomers and forms hetero-oligomers with alpha-synuclein. E Israeli R Sharon, J Neurochem 2009 108 2 465 474 10.1111/j.1471-4159.2008.05776.x 19012742
-
(2009)
J Neurochem
, vol.108
, Issue.2
, pp. 465-474
-
-
Israeli, E.1
Sharon, R.2
-
35
-
-
0025061059
-
The Lewy body variant of Alzheimer's disease: A clinical and pathologic entity
-
2153271
-
The Lewy body variant of Alzheimer's disease: a clinical and pathologic entity. L Hansen D Salmon D Galasko E Masliah R Katzman R DeTeresa L Thal MM Pay R Hofstetter M Klauber,, et al. Neurology 1990 40 1 1 8 2153271
-
(1990)
Neurology
, vol.40
, Issue.1
, pp. 1-8
-
-
Hansen, L.1
Salmon, D.2
Galasko, D.3
Masliah, E.4
Katzman, R.5
Deteresa, R.6
Thal, L.7
Pay, M.M.8
Hofstetter, R.9
Klauber, M.10
-
36
-
-
18344417178
-
Lewy bodies contain altered alpha-synuclein in brains of many familial Alzheimer's disease patients with mutations in presenilin and amyloid precursor protein genes
-
9811326
-
Lewy bodies contain altered alpha-synuclein in brains of many familial Alzheimer's disease patients with mutations in presenilin and amyloid precursor protein genes. CF Lippa H Fujiwara DM Mann B Giasson M Baba ML Schmidt LE Nee B O'Connell DA Pollen P St George-Hyslop,, et al. Am J Pathol 1998 153 5 1365 1370 9811326
-
(1998)
Am J Pathol
, vol.153
, Issue.5
, pp. 1365-1370
-
-
Lippa, C.F.1
Fujiwara, H.2
Mann, D.M.3
Giasson, B.4
Baba, M.5
Schmidt, M.L.6
Nee, L.E.7
O'Connell, B.8
Pollen, D.A.9
St George-Hyslop, P.10
-
37
-
-
0031762949
-
Fatal attractions: Abnormal protein aggregation and neuron death in Parkinson's disease and Lewy body dementia
-
10.1038/sj.cdd.4400432. 10203692
-
Fatal attractions: abnormal protein aggregation and neuron death in Parkinson's disease and Lewy body dementia. JQ Trojanowski M Goedert T Iwatsubo VM Lee, Cell Death Differ 1998 5 10 832 837 10.1038/sj.cdd.4400432 10203692
-
(1998)
Cell Death Differ
, vol.5
, Issue.10
, pp. 832-837
-
-
Trojanowski, J.Q.1
Goedert, M.2
Iwatsubo, T.3
Lee, V.M.4
-
38
-
-
0033919992
-
Lewy bodies in Alzheimer's disease: A neuropathological review of 145 cases using alpha-synuclein immunohistochemistry
-
10.1111/j.1750-3639.2000.tb00269.x. 10885656
-
Lewy bodies in Alzheimer's disease: a neuropathological review of 145 cases using alpha-synuclein immunohistochemistry. RL Hamilton, Brain Pathol 2000 10 3 378 384 10.1111/j.1750-3639.2000.tb00269.x 10885656
-
(2000)
Brain Pathol
, vol.10
, Issue.3
, pp. 378-384
-
-
Hamilton, R.L.1
-
39
-
-
49149124343
-
Amyloid- protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory
-
10.1038/nm1782. 18568035
-
Amyloid- protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory. GM Shankar S Li TH Mehta A Garcia-Munoz NE Shepardson I Smith FM Brett MA Farrell MJ Rowan CA Lemere,, et al. Nat Med 2008 14 8 837 842 10.1038/nm1782 18568035
-
(2008)
Nat Med
, vol.14
, Issue.8
, pp. 837-842
-
-
Shankar, G.M.1
Li, S.2
Mehta, T.H.3
Garcia-Munoz, A.4
Shepardson, N.E.5
Smith, I.6
Brett, F.M.7
Farrell, M.A.8
Rowan, M.J.9
Lemere, C.A.10
-
40
-
-
1842732209
-
Oligomerization of Alzheimer's -Amyloid within Processes and Synapses of Cultured Neurons and Brain
-
10.1523/JNEUROSCI.5167-03.2004. 15071107
-
Oligomerization of Alzheimer's -Amyloid within Processes and Synapses of Cultured Neurons and Brain. RH Takahashi CG Almeida PF Kearney F Yu MT Lin TA Milner GK Gouras, J Neurosci 2004 24 14 3592 3599 10.1523/JNEUROSCI.5167-03.2004 15071107
-
(2004)
J Neurosci
, vol.24
, Issue.14
, pp. 3592-3599
-
-
Takahashi, R.H.1
Almeida, C.G.2
Kearney, P.F.3
Yu, F.4
Lin, M.T.5
Milner, T.A.6
Gouras, G.K.7
-
41
-
-
0037041426
-
Naturally secreted oligomers of amyloid protein potently inhibit hippocampal long-term potentiation in vivo
-
10.1038/416535a. 11932745
-
Naturally secreted oligomers of amyloid protein potently inhibit hippocampal long-term potentiation in vivo. DM Walsh I Klyubin JV Fadeeva WK Cullen R Anwyl MS Wolfe MJ Rowan DJ Selkoe, Nature 2002 416 6880 535 539 10.1038/416535a 11932745
-
(2002)
Nature
, vol.416
, Issue.6880
, pp. 535-539
-
-
Walsh, D.M.1
Klyubin, I.2
Fadeeva, J.V.3
Cullen, W.K.4
Anwyl, R.5
Wolfe, M.S.6
Rowan, M.J.7
Selkoe, D.J.8
-
42
-
-
0029938770
-
The synaptic protein NACP is abnormally expressed during the progression of Alzheimer's disease
-
DOI 10.1016/0006-8993(96)00014-5
-
The synaptic protein NACP is abnormally expressed during the progression of Alzheimer's disease. A Iwai E Masliah MP Sundsmo R DeTeresa M Mallory DP Salmon T Saitoh, Brain Res 1996 720 1-2 230 234 10.1016/0006-8993(96)00014-5 8782917 (Pubitemid 26179830)
-
(1996)
Brain Research
, vol.720
, Issue.1-2
, pp. 230-234
-
-
Iwai, A.1
Masliah, E.2
Sundsmo, M.P.3
DeTeresa, R.4
Mallory, M.5
Salmon, D.P.6
Saitoh, T.7
-
43
-
-
70349895344
-
Role of Synucleins in Alzheimer's Disease
-
10.1007/s12640-009-9073-6
-
Role of Synucleins in Alzheimer's Disease. L Crews I Tsigelny M Hashimoto E Masliah, Neurotoxicity Res 2009 16 3 306 317 10.1007/s12640-009-9073-6
-
(2009)
Neurotoxicity Res
, vol.16
, Issue.3
, pp. 306-317
-
-
Crews, L.1
Tsigelny, I.2
Hashimoto, M.3
Masliah, E.4
-
44
-
-
0035834076
-
-amyloid peptides enhance alpha-synuclein accumulation and neuronal deficits in a transgenic mouse model linking Alzheimer's disease and Parkinson's disease
-
10.1073/pnas.211412398. 11572944
-
-amyloid peptides enhance alpha-synuclein accumulation and neuronal deficits in a transgenic mouse model linking Alzheimer's disease and Parkinson's disease. E Masliah E Rockenstein I Veinbergs Y Sagara M Mallory M Hashimoto L Mucke, Proc Natl Acad Sci USA 2001 98 21 12245 12250 10.1073/pnas.211412398 11572944
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, Issue.21
, pp. 12245-12250
-
-
Masliah, E.1
Rockenstein, E.2
Veinbergs, I.3
Sagara, Y.4
Mallory, M.5
Hashimoto, M.6
Mucke, L.7
-
45
-
-
0037200117
-
Oligomeric and Fibrillar Species of Amyloid- Peptides Differentially Affect Neuronal Viability
-
Oligomeric and Fibrillar Species of Amyloid- Peptides Differentially Affect Neuronal Viability. KN Dahlgren AM Manelli WB Stine Jr. LK Baker GA Krafft MJ LaDu, JBiolChem 2002 277 35 32046 32053
-
(2002)
JBiolChem
, vol.277
, Issue.35
, pp. 32046-32053
-
-
Dahlgren, K.N.1
Manelli, A.M.2
Stine Jr., W.B.3
Baker, L.K.4
Krafft, G.A.5
Ladu, M.J.6
-
46
-
-
0027447286
-
Neurodegeneration induced by -amyloid peptides in vitro: The role of peptide assembly state
-
8463843
-
Neurodegeneration induced by -amyloid peptides in vitro: the role of peptide assembly state. CJ Pike D Burdick AJ Walencewicz CG Glabe CW Cotman, J Neurosci 1993 13 4 1676 1687 8463843
-
(1993)
J Neurosci
, vol.13
, Issue.4
, pp. 1676-1687
-
-
Pike, C.J.1
Burdick, D.2
Walencewicz, A.J.3
Glabe, C.G.4
Cotman, C.W.5
-
47
-
-
11544279355
-
1-42are potent central nervous system neurotoxins
-
10.1073/pnas.95.11.6448. 9600986
-
1-42are potent central nervous system neurotoxins. MP Lambert AK Barlow BA Chromy C Edwards R Freed M Liosatos TE Morgan I Rozovsky B Trommer KL Viola,, et al. Proc Natl Acad Sci USA 1998 95 11 6448 6453 10.1073/pnas.95.11.6448 9600986
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, Issue.11
, pp. 6448-6453
-
-
Lambert, M.P.1
Barlow, A.K.2
Chromy, B.A.3
Edwards, C.4
Freed, R.5
Liosatos, M.6
Morgan, T.E.7
Rozovsky, I.8
Trommer, B.9
Viola, K.L.10
-
48
-
-
33846633336
-
A Oligomer-Induced Aberrations in Synapse Composition, Shape, and Density Provide a Molecular Basis for Loss of Connectivity in Alzheimer's Disease
-
10.1523/JNEUROSCI.3501-06.2007. 17251419
-
A Oligomer-Induced Aberrations in Synapse Composition, Shape, and Density Provide a Molecular Basis for Loss of Connectivity in Alzheimer's Disease. PN Lacor MC Buniel PW Furlow A Sanz Clemente PT Velasco M Wood KL Viola WL Klein, J Neurosci 2007 27 4 796 807 10.1523/JNEUROSCI.3501-06.2007 17251419
-
(2007)
J Neurosci
, vol.27
, Issue.4
, pp. 796-807
-
-
Lacor, P.N.1
Buniel, M.C.2
Furlow, P.W.3
Sanz Clemente, A.4
Velasco, P.T.5
Wood, M.6
Viola, K.L.7
Klein, W.L.8
-
49
-
-
33947314641
-
Natural Oligomers of the Alzheimer Amyloid- Protein Induce Reversible Synapse Loss by Modulating an NMDA-Type Glutamate Receptor-Dependent Signaling Pathway
-
10.1523/JNEUROSCI.4970-06.2007. 17360908
-
Natural Oligomers of the Alzheimer Amyloid- Protein Induce Reversible Synapse Loss by Modulating an NMDA-Type Glutamate Receptor-Dependent Signaling Pathway. GM Shankar BL Bloodgood M Townsend DM Walsh DJ Selkoe BL Sabatini, J Neurosci 2007 27 11 2866 2875 10.1523/JNEUROSCI.4970-06.2007 17360908
-
(2007)
J Neurosci
, vol.27
, Issue.11
, pp. 2866-2875
-
-
Shankar, G.M.1
Bloodgood, B.L.2
Townsend, M.3
Walsh, D.M.4
Selkoe, D.J.5
Sabatini, B.L.6
-
50
-
-
33847662852
-
Soluble protein oligomers in neurodegeneration: Lessons from the Alzheimer's amyloid -peptide
-
10.1038/nrm2101. 17245412
-
Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid -peptide. C Haass DJ Selkoe, Nat Rev Mol Cell Biol 2007 8 2 101 112 10.1038/nrm2101 17245412
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, Issue.2
, pp. 101-112
-
-
Haass, C.1
Selkoe, D.J.2
-
51
-
-
0034488295
-
Generation of an Apoptotic Intracellular Peptide by -Secretase Cleavage of Alzheimer's Amyloid Protein Precursor
-
Generation of an Apoptotic Intracellular Peptide by -Secretase Cleavage of Alzheimer's Amyloid Protein Precursor. B Passer L Pellegrini C Russo RM Siegel MJ Lenardo G Schettini M Bachmann M Tabaton L D'Adamio, JAlzheimersDis 2000 2 289 301
-
(2000)
JAlzheimersDis
, vol.2
, pp. 289-301
-
-
Passer, B.1
Pellegrini, L.2
Russo, C.3
Siegel, R.M.4
Lenardo, M.J.5
Schettini, G.6
Bachmann, M.7
Tabaton, M.8
D'Adamio, L.9
-
52
-
-
16044373524
-
Secreted amyloid -protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease
-
10.1038/nm0896-864. 8705854
-
Secreted amyloid -protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease. D Scheuner C Eckman M Jensen X Song M Citron N Suzuki TD Bird J Hardy M Hutton W Kukull,, et al. Nat Med 1996 2 8 864 870 10.1038/nm0896-864 8705854
-
(1996)
Nat Med
, vol.2
, Issue.8
, pp. 864-870
-
-
Scheuner, D.1
Eckman, C.2
Jensen, M.3
Song, X.4
Citron, M.5
Suzuki, N.6
Bird, T.D.7
Hardy, J.8
Hutton, M.9
Kukull, W.10
-
53
-
-
10744220713
-
Structural properties of Gerstmann-Straussler-Scheinker disease amyloid protein
-
Structural properties of Gerstmann-Straussler-Scheinker disease amyloid protein. M Salmona M Morbin T Massignan L Colombo G Mazzoleni R Capobianco L Diomede F Thaler L Mollica G Musco,, et al. JBiolChem 2003 278 48 48146 48153
-
(2003)
JBiolChem
, vol.278
, Issue.48
, pp. 48146-48153
-
-
Salmona, M.1
Morbin, M.2
Massignan, T.3
Colombo, L.4
Mazzoleni, G.5
Capobianco, R.6
Diomede, L.7
Thaler, F.8
Mollica, L.9
Musco, G.10
-
54
-
-
0030896414
-
Isolation and culture of adult rat hippocampal neurons
-
DOI 10.1016/S0165-0270(96)00136-7, PII S0165027096001367
-
Isolation and culture of adult rat hippocampal neurons. GJ Brewer, J Neurosci Meth 1997 71 2 143 155 10.1016/S0165-0270(96)00136-7 (Pubitemid 27152111)
-
(1997)
Journal of Neuroscience Methods
, vol.71
, Issue.2
, pp. 143-155
-
-
Brewer, G.J.1
-
55
-
-
0032490945
-
Kinetics and regulation of fast endocytosis at hippocampal synapses
-
10.1038/29079. 9707119
-
Kinetics and regulation of fast endocytosis at hippocampal synapses. J Klingauf ET Kavalali RW Tsien, Nature 1998 394 6693 581 585 10.1038/29079 9707119
-
(1998)
Nature
, vol.394
, Issue.6693
, pp. 581-585
-
-
Klingauf, J.1
Kavalali, E.T.2
Tsien, R.W.3
-
56
-
-
33644929740
-
Synaptosomal glutamate release and uptake in mice lacking the cellular prion protein
-
10.1016/j.brainres.2005.12.045. 16519879
-
Synaptosomal glutamate release and uptake in mice lacking the cellular prion protein. ME Thais CL Carqueja TG Santos RV Silva E Stroeh RS Machado DO Wahlheim MM Bianchin AC Sakamoto RR Brentani,, et al. Brain Res 2006 1075 1 13 19 10.1016/j.brainres.2005.12.045 16519879
-
(2006)
Brain Res
, vol.1075
, Issue.1
, pp. 13-19
-
-
Thais, M.E.1
Carqueja, C.L.2
Santos, T.G.3
Silva, R.V.4
Stroeh, E.5
MacHado, R.S.6
Wahlheim, D.O.7
Bianchin, M.M.8
Sakamoto, A.C.9
Brentani, R.R.10
|