Purification of reversibly oxidized proteins (PROP) reveals a redox switch controlling p38 MAP kinase activity

PLoS ONE

Volumn 5, Issue 11, 2010, Pages

  Templeton, Dennis J ^a   Aye, Myo Sabai ^a   Rady, Joshua ^a   Xu, Fang ^a   Cross, Janet V ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTEINE; HYDROGEN PEROXIDE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROSTAGLANDIN J2; 9-DEOXY-DELTA-9-PROSTAGLANDIN D2; DRUG DERIVATIVE; MITOGEN ACTIVATED PROTEIN KINASE 14; OXIDIZING AGENT; PROSTAGLANDIN D2; PROTEIN; THIOL DERIVATIVE;

ARTICLE; CELL METABOLISM; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE MAPPING; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNODETECTION; IMMUNOPRECIPITATION; METHODOLOGY; NITROSYLATION; OSMOSIS; OXIDATION; OXIDATION REDUCTION STATE; PROTEIN ANALYSIS; PROTEIN PURIFICATION; PURIFICATION OF REVERSIBLY OXIDIZED PROTEINS; SIGNAL TRANSDUCTION; CHEMICAL ANALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECT; GENETIC TRANSFECTION; GENETICS; HELA CELL; ISOLATION AND PURIFICATION; METABOLISM; MUTATION; OXIDATION REDUCTION REACTION; PROTEIN CONFORMATION; REPRODUCIBILITY;

CHEMISTRY TECHNIQUES, ANALYTICAL; CYSTEINE; HELA CELLS; HUMANS; HYDROGEN PEROXIDE; IMMUNOBLOTTING; MITOGEN-ACTIVATED PROTEIN KINASE 14; MODELS, MOLECULAR; MUTATION; OXIDANTS; OXIDATION-REDUCTION; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROSTAGLANDIN D2; PROTEIN CONFORMATION; PROTEINS; REPRODUCIBILITY OF RESULTS; SIGNAL TRANSDUCTION; SULFHYDRYL COMPOUNDS; TRANSFECTION;

EID: 78649735992     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0015012     Document Type: Article

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