Reevaluation of trkA expression as a biological marker of neuroblastoma by high-sensitivity expression analysis-a study of 106 primary neuroblastomas treated in a single institute

Journal of Pediatric Surgery

Volumn 45, Issue 12, 2010, Pages 2293-2298

  Hishiki, Tomoro ^a   Saito, Takeshi ^a   Terui, Keita ^a   Sato, Yoshiharu ^a   Takenouchi, Ayako ^a   Yahata, Eriko ^a   Ono, Sachie ^a   Nakagawara, Akira ^b   Kamijo, Takehiko ^b   Nakamura, Yohko ^b   Matsunaga, Tadashi ^a   Yoshida, Hideo ^a  

^a CHIBA UNIVERSITY   (Japan)

^b CHIBA CANCER CENTER   (Japan)

Author keywords

Neuroblastoma; Quantitative PCR; Real time PCR; TrkA

Indexed keywords

PROTEIN TYROSINE KINASE A; TUMOR MARKER;

AGE; ARTICLE; CANCER STAGING; CHILD; CLINICAL EVALUATION; CONTROLLED STUDY; CORRELATIONAL STUDY; GENE AMPLIFICATION; GENE EXPRESSION; GENE PROBE; GENETIC VARIABILITY; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; NEUROBLASTOMA; PLOIDY; POLYMERASE CHAIN REACTION; PRIMARY TUMOR; PRIORITY JOURNAL; PROGNOSIS; QUANTITATIVE ANALYSIS; TREATMENT OUTCOME;

AGE FACTORS; CHILD, PRESCHOOL; DNA, NEOPLASM; FEMALE; GENE AMPLIFICATION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, MYC; HUMANS; INFANT; JAPAN; MALE; NEOPLASM PROTEINS; NEOPLASM STAGING; NEUROBLASTOMA; PLOIDIES; PROGNOSIS; RECEPTOR, TRKA; RETROSPECTIVE STUDIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TUMOR MARKERS, BIOLOGICAL;

EID: 78649725023     PISSN: 00223468     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpedsurg.2010.08.021     Document Type: Article

References (21)

1. Bolande R.P. The neurocristopathies: a unifying concept of disease arising in neural crest maldevelopment Hum Pathol 5 1974 409 429
2. Brodeur G.M., and Nakagawara A. Molecular basis of clinical heterogeneity in neuroblastoma Am J Pediatr Hematol Oncol 14 1992 111 116
3. Nakagawara A., and Brodeur G.M. Role of neurotrophins and their receptors in human neuroblastomas: a primary culture study Eur J Cancer 33 1997 2050 2053
4. Nakagawara A., Arima-Nakagawara M., and Scavarda N.J. Association between high levels of expression of the TRK gene and favorable outcome in human neuroblastoma N Engl J Med 328 1993 847 854
5. Borrello M.G., Bongarzone I., and Pierotti M.A. trk and ret proto-oncogene expression in human neuroblastoma specimens: high frequency of trk expression in non-advanced stages Int J Cancer 54 1993 540 545
6. Kogner P., Barbany G., and Dominici C. Coexpression of messenger RNA for TRK protooncogene and low affinity nerve growth factor receptor in neuroblastoma with favorable prognosis Cancer Res 53 1993 2044 2050
7. Miyake M., Suzuki T., and Shimada H. High affinity nerve growth factor receptor expression (gp140 trkA), N-myc amplification, histopathology, and survival in neuroblastoma Progr Clin Biol Res 385 1994 163 168
8. Kramer K., Cheung N.K., and Gerald W.L. Correlation of MYCN amplification, Trk-A and CD44 expression with clinical stage in 250 patients with neuroblastoma Eur J Cancer 33 1997 2098 2100
9. Matsunaga T., Shirasawa H., and Enomoto H. Neuronal src and trk A protooncogene expression in neuroblastomas and patient prognosis Int J Cancer 79 1998 226 231
10. Tajiri T., Higashi M., and Souzaki R. Classification of neuroblastomas based on an analysis of the expression of genes related to prognosis JPediatr Surg 42 2007 2046 2049
11. Shimada H., Nakagawa A., and Peters J. TrkA expression in peripheral neuroblastic tumors: prognostic significance and biological relevance Cancer 101 2004 1873 1881
12. Hishiki T., Nimura Y., and Isogai E. Glial cell line-derived neurotrophic factor/neurturin-induced differentiation and its enhancement by retinoic acid in primary human neuroblastomas expressing c-Ret, GFRalpha-1, and GFRalpha-2 Cancer Res 58 1998 2158 2165
13. Tacconelli A., Farina A.R., and Cappabianca L. TrkA alternative splicing: a regulated tumor-promoting switch in human neuroblastoma Cancer Cell. 6 2004 347 360
14. Brodeur G.M., Seeger R.C., and Barrett A. International criteria for diagnosis, staging, and response to treatment in patients with neuroblastoma J Clin Oncol 6 1988 1874 1881
15. Sawada T., Hirayama M., and Nakata T. Mass screening for neuroblastoma in infants in Japan. Interim report of a mass screening group Lancet 2 1984 271 273
16. Kaneko M., Tsuchida Y., and Uchino J. Treatment results of advanced neuroblastoma with the first Japanese study group protocol. Study Group of Japan for Treatment of Advanced Neuroblastoma J Pediatr Hematol Oncol 21 1999 190 197
17. Iehara T., Hosoi H., and Akazawa K. MYCN gene amplification is a powerful prognostic factor even in infantile neuroblastoma detected by mass screening Br J Cancer 94 2006 1510 1515
18. Gotoh T., Hosoi H., and Iehara T. Prediction of MYCN amplification in neuroblastoma using serum DNA and real-time quantitative polymerase chain reaction J Clin Oncol 23 2005 5205 5210
19. Ootsuka S., Asami S., and Sasaki T. Analyses of novel prognostic factors in neuroblastoma patients Biol Pharm Bull 30 2007 2294 2299
20. Huggett J., Dheda K., and Bustin S. Real-time RT-PCR normalisation; strategies and considerations Genes Immun 6 2005 279 284
21. Thellin O., Zorzi W., and Lakaye B. Housekeeping genes as internal standards: use and limits J Biotechnol 75 1999 291 295