Preventing vasospasm improves outcome after aneurysmal subarachnoid hemorrhage: Rationale and design of CONSCIOUS-2 and CONSCIOUS-3 trials

Neurocritical Care

Volumn 13, Issue 3, 2010, Pages 416-424

  MacDonald, R Loch ^j   Higashida, Randall T ^a   Keller, Emanuela ^b   Mayer, Stephan A ^c   Molyneux, Andy ^d   Raabe, Andreas ^e   Vajkoczy, Peter ^f   Wanke, Isabel ^g   Frey, Aline ^h   Marr, Angelina ^h   Roux, Sébastien ^h   Kassell, Neal F ⁱ  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^c Och Spine at New York Presbyterian Hospitals   (United States)

^d UNIVERSITY OF OXFORD   (United Kingdom)

^e UNIVERSITY OF BERN   (Switzerland)

^f CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^g KLINIK HIRSLANDEN   (Switzerland)

^h ACTELION PHARMACEUTICALS LTD   (Switzerland)

ⁱ UNIVERSITY OF VIRGINIA   (United States)

^j NONE

more..

Author keywords

Aneurysmal subarachnoid hemorrhage; Cerebral vasospasm; Clazosentan; Clinical outcome; CONSCIOUS studies

Indexed keywords

CLAZOSENTAN; PLACEBO;

ADULT; AGED; ARTICLE; BRAIN ARTERY ANEURYSM RUPTURE; BRAIN INFARCTION; BRAIN VASOSPASM; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; GLASGOW COMA SCALE; HUMAN; MAJOR CLINICAL STUDY; MORTALITY; MULTICENTER STUDY; PATIENT CARE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; STUDY DESIGN; SUBARACHNOID HEMORRHAGE; TREATMENT OUTCOME;

COMBINED MODALITY THERAPY; DIOXANES; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; PLACEBOS; POSTOPERATIVE COMPLICATIONS; PRACTICE GUIDELINES AS TOPIC; PYRIDINES; PYRIMIDINES; RANDOMIZED CONTROLLED TRIALS AS TOPIC; RECEPTOR, ENDOTHELIN A; SUBARACHNOID HEMORRHAGE; SULFONAMIDES; TETRAZOLES; VASOSPASM, INTRACRANIAL;

EID: 78649707804     PISSN: 15416933     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12028-010-9433-3     Document Type: Article

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