Molecular determination of RHD zygosity:predicting risk of hemolytic disease of the fetus and newborn related to anti-D

Prenatal Diagnosis

Volumn 30, Issue 12-13, 2010, Pages 1207-1212

  Pirelli, Kevin J ^a   Pietz, Bradley C ^a   Johnson, Susan T ^a   Pinder, Holly L ^a   Bellissimo, Daniel B ^a  

^a BLOOD RESEARCH INSTITUTE   (United States)

Author keywords

HDFN; RHD; RHD variants; Zygosity

Indexed keywords

RHESUS D ANTIBODY; RHESUS D ANTIGEN;

AFRICAN AMERICAN; ARTICLE; CAUCASIAN; EXON; GENE; GENOTYPE; HUMAN; HUMAN TISSUE; NEWBORN HEMOLYTIC DISEASE; PHENOTYPE; POLYMERASE CHAIN REACTION; PRENATAL PERIOD; PRIORITY JOURNAL; RHD GENE; RISK ASSESSMENT; ZYGOSITY;

ERYTHROBLASTOSIS, FETAL; FEMALE; GENOTYPE; HETEROZYGOTE; HUMANS; INFANT, NEWBORN; ISOANTIBODIES; MALE; MOLECULAR DIAGNOSTIC TECHNIQUES; POLYMERASE CHAIN REACTION; PREGNANCY; PRENATAL DIAGNOSIS; PROGNOSIS; RH-HR BLOOD-GROUP SYSTEM; RISK FACTORS; SEROLOGIC TESTS;

EID: 78649678449     PISSN: 01973851     EISSN: 10970223     Source Type: Journal    
DOI: 10.1002/pd.2652     Document Type: Article

References (14)

1. AABB. 2008. AABB Technical Manual (16th edn), AABB. Roback JD, Combs MR, Grossman BJ, Hillyer CD (eds.).
2. Avent ND, Reid ME. 2000. The Rh blood group system: a review. Blood 95(2): 375-387. Available from: PM:10627438.
3. Chiu RW, Murphy MF, Fidler C, Zee BC, Wainscoat JS, Lo YM. 2001. Determination of RhD zygosity: comparison of a double amplification refractory mutation system approach and a multiplex real-time quantitative PCR approach. Clin Chem 47(4): 667-672. Available from: PM:11274016.
4. Finning KM, Martin PG, Soothill PW, Avent ND. 2002. Prediction of fetal D status from maternal plasma: introduction of a new noninvasive fetal RHD genotyping service. Transfusion 42(8): 1079-1085. Available from: PM:12385421.
5. Grootkerk-Tax MG, Maaskant-van Wijk PA, van Drunen J, van der Schoot CE. 2005. The highly variable RH locus in nonwhite persons hampers RHD zygosity determination but yields more insight into RH-related evolutionary events. Transfusion 45(3): 327-337. Available from: PM:15752149.
6. Krog GR, Clausen FB, Dziegiel MH. 2007. Quantitation of RHD by real-time polymerase chain reaction for determination of RHD zygosity and RHD mosaicism/chimerism: an evaluation of four quantitative methods. Transfusion 47(4): 715-722. Available from: PM:17381631.
7. Li Y, Zimmermann B, Zhong XY, Gupta AK, Holzgreve W, Hahn S. 2003. Determination of RHD zygosity using real-time quantitative PCR. Swiss Med Wkly 133(31-32): 442-445. Available from: PM:14562188.
8. Matheson KA, Denomme GA. 2002. Novel 3'Rhesus box sequences confound RHD zygosity assignment. Transfusion 42(5): 645-650. Available from: PM:12084174.
9. Moise KJ, Jr 2008. Management of rhesus alloimmunization in pregnancy. Obstet Gynecol 112(1): 164-176. Available from: PM:18591322.
10. Pertl B, Pieber D, Panzitt T, et al. 2000. RhD genotyping by quantitative fluorescent polymerase chain reaction: a new approach. BJOG 107(12): 1498-1502. Available from: PM:11192106.
11. Reid ME, Lomas-Francis C. 2004. The Blood Grop Antigen Facts Book (2nd edn). Elsevier Academic Press: London.
12. Singleton BK, Green CA, Avent ND, et al. 2000. The presence of an RHD pseudogene containing a 37 base pair duplication and a nonsense mutation in africans with the Rh D-negative blood group phenotype. Blood 95(1): 12-18. Available from: PM:10607679.
13. Wagner FF, Flegel WA. 2000. RHD gene deletion occurred in the Rhesus box. Blood 95(12): 3662-3668. Available from: PM:10845894.
14. Wagner FF, Moulds JM, Flegel WA. 2005. Genetic mechanisms of Rhesus box variation. Transfusion 45(3): 338-344. Available from: PM:15752150.