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Volumn 77, Issue 6, 2010, Pages 587-596

Bladder cancer: Current management and opportunities for a personalized approach

Author keywords

bladder cancer; muscle invasive; non muscle invasive; personalized medicine; urothelial carcinoma

Indexed keywords

ALPHA2B INTERFERON; BCG VACCINE; BEVACIZUMAB; CARBOPLATIN; CISPLATIN; CYCLOPHOSPHAMIDE; DASATINIB; DOCETAXEL; DOXORUBICIN; ERLOTINIB; FLUOROURACIL; GEMCITABINE; IFOSFAMIDE; LAPATINIB; METHOTREXATE; PACLITAXEL; PEMETREXED; SUNITINIB; TRASTUZUMAB; VINBLASTINE;

EID: 78649666335     PISSN: 00272507     EISSN: 19317581     Source Type: Journal    
DOI: 10.1002/msj.20224     Document Type: Review
Times cited : (6)

References (59)
  • 2
    • 34247337239 scopus 로고    scopus 로고
    • Molecular pathways in invasive bladder cancer: New insights into mechanisms, progression, and target identification
    • Mitra AP, Datar RH, Cote RJ., Molecular pathways in invasive bladder cancer: new insights into mechanisms, progression, and target identification. J Clin Oncol 2006; 24: 5552-5564.
    • (2006) J Clin Oncol , vol.24 , pp. 5552-5564
    • Mitra, A.P.1    Datar, R.H.2    Cote, R.J.3
  • 3
    • 78649647797 scopus 로고    scopus 로고
    • Identification and characterization of FGFR3 mutations in high-grade bladder cancer
    • Abstract 296
    • Iyer G, Lin O, Al-Ahmadie H, et al., Identification and characterization of FGFR3 mutations in high-grade bladder cancer. ASCO Genitourinary Cancers Symposium 2010: Abstract 296.
    • (2010) ASCO Genitourinary Cancers Symposium
    • Iyer, G.1    Lin, O.2    Al-Ahmadie, H.3
  • 4
    • 63049094489 scopus 로고    scopus 로고
    • Inactivation of p53 and Pten promotes invasive bladder cancer
    • Puzio-Kuter AM, Castillo-Martin M, Kinkade CW, et al., Inactivation of p53 and Pten promotes invasive bladder cancer. Genes Dev 2009; 23: 675-680.
    • (2009) Genes Dev , vol.23 , pp. 675-680
    • Puzio-Kuter, A.M.1    Castillo-Martin, M.2    Kinkade, C.W.3
  • 5
    • 33748925553 scopus 로고    scopus 로고
    • Clinical model of lifetime cost of treating bladder cancer and associated complications
    • Avritscher EB, Cooksley CD, Grossman HB, et al., Clinical model of lifetime cost of treating bladder cancer and associated complications. Urology 2006; 68: 549-553.
    • (2006) Urology , vol.68 , pp. 549-553
    • Avritscher, E.B.1    Cooksley, C.D.2    Grossman, H.B.3
  • 6
    • 0026692990 scopus 로고
    • Carcinoma in situ
    • Lamm DL., Carcinoma in situ. Urol Clin North Am 1992; 19: 499-508.
    • (1992) Urol Clin North Am , vol.19 , pp. 499-508
    • Lamm, D.L.1
  • 7
    • 0018933863 scopus 로고
    • The significance of lamina propria invasion on the prognosis of patients with bladder tumors
    • Anderström C, Johansson S, Nilsson S., The significance of lamina propria invasion on the prognosis of patients with bladder tumors. J Urol 1980; 124: 23-26.
    • (1980) J Urol , vol.124 , pp. 23-26
    • Anderström, C.1    Johansson, S.2    Nilsson, S.3
  • 8
    • 0037213728 scopus 로고    scopus 로고
    • A retrospective analysis of 153 patients treated with or without intravesical bacillus Calmette-Guerin for primary stage T1 grade 3 bladder cancer: Recurrence, progression and survival
    • Shahin O, Thalmann GN, Rentsch C, et al., A retrospective analysis of 153 patients treated with or without intravesical bacillus Calmette-Guerin for primary stage T1 grade 3 bladder cancer: recurrence, progression and survival. J Urol 2003; 169: 96-100.
    • (2003) J Urol , vol.169 , pp. 96-100
    • Shahin, O.1    Thalmann, G.N.2    Rentsch, C.3
  • 9
    • 78649644906 scopus 로고    scopus 로고
    • Prospective trial to identify optimal bladder cancer surveillance protocol: Reducing costs while maximizing sensitivity
    • Karam J, Shah J, Kader AK, et al., Prospective trial to identify optimal bladder cancer surveillance protocol: reducing costs while maximizing sensitivity. ASCO Genitourinary Cancers Symposium 2010: Abstract 275.
    • (2010) ASCO Genitourinary Cancers Symposium: Abstract 275
    • Karam, J.1    Shah, J.2    Kader, A.K.3
  • 10
    • 0035254218 scopus 로고    scopus 로고
    • Radical cystectomy in the treatment of invasive bladder cancer: Long-term results in 1,054 patients
    • Stein JP, Lieskovsky G, Cote R, et al., Radical cystectomy in the treatment of invasive bladder cancer: long-term results in 1,054 patients. J Clin Oncol 2001; 19: 666-675.
    • (2001) J Clin Oncol , vol.19 , pp. 666-675
    • Stein, J.P.1    Lieskovsky, G.2    Cote, R.3
  • 11
    • 0041429507 scopus 로고    scopus 로고
    • Neoadjuvant chemotherapy plus cystectomy compared with cystectomy alone for locally advanced bladder cancer
    • Grossman HB, Natale RB, Tangen CM, et al., Neoadjuvant chemotherapy plus cystectomy compared with cystectomy alone for locally advanced bladder cancer. N Engl J Med 2003; 349: 859-866.
    • (2003) N Engl J Med , vol.349 , pp. 859-866
    • Grossman, H.B.1    Natale, R.B.2    Tangen, C.M.3
  • 12
    • 85014013850 scopus 로고    scopus 로고
    • Neoadjuvant cisplatin, methotrexate, and vinblastine chemotherapy for muscle-invasive bladder cancer: A randomised controlled trial. International Collaboration of Trialists [published correction appears in Lancet 1999;354:1650]
    • Neoadjuvant cisplatin, methotrexate, and vinblastine chemotherapy for muscle-invasive bladder cancer: a randomised controlled trial. International Collaboration of Trialists [published correction appears in Lancet 1999;354:1650]. Lancet 1999; 354: 533-540.
    • (1999) Lancet , vol.354 , pp. 533-540
  • 13
    • 0012614503 scopus 로고    scopus 로고
    • Updated results of a randomized controlled trial of neoadjuvant cisplatin, methotrexate and vinblastine chemotherapy for muscle-invasive bladder cancer
    • Abstract 710
    • Hall RR., Updated results of a randomized controlled trial of neoadjuvant cisplatin, methotrexate and vinblastine chemotherapy for muscle-invasive bladder cancer. Proc Am Soc Clin Oncol 2002; 21:Abstract 710.
    • (2002) Proc Am Soc Clin Oncol , vol.21
    • Hall, R.R.1
  • 14
    • 34447095141 scopus 로고    scopus 로고
    • Low incidence of perioperative chemotherapy for stage III bladder cancer 1998 to 2003: A report from the National Cancer Data Base
    • David KA, Milowsky MI, Ritchey J, et al., Low incidence of perioperative chemotherapy for stage III bladder cancer 1998 to 2003: a report from the National Cancer Data Base. J Urol 2007; 178: 451-454.
    • (2007) J Urol , vol.178 , pp. 451-454
    • David, K.A.1    Milowsky, M.I.2    Ritchey, J.3
  • 15
    • 33748470523 scopus 로고    scopus 로고
    • Postoperative nomogram predicting risk of recurrence after radical cystectomy for bladder cancer
    • Bochner BH, Kattan MW, Vora KC., Postoperative nomogram predicting risk of recurrence after radical cystectomy for bladder cancer. J Clin Oncol 2006; 24: 3967-3972.
    • (2006) J Clin Oncol , vol.24 , pp. 3967-3972
    • Bochner, B.H.1    Kattan, M.W.2    Vora, K.C.3
  • 16
    • 77951753798 scopus 로고    scopus 로고
    • International validation of the prognostic value of lymphovascular invasion in patients treated with radical cystectomy
    • Shariat SF, Svatek RS, Tilki D, et al., International validation of the prognostic value of lymphovascular invasion in patients treated with radical cystectomy. BJU Int 2010; 105: 1402-1412.
    • (2010) BJU Int , vol.105 , pp. 1402-1412
    • Shariat, S.F.1    Svatek, R.S.2    Tilki, D.3
  • 17
    • 34547670602 scopus 로고    scopus 로고
    • Emmprin and survivin predict response and survival following cisplatin-containing chemotherapy in patients with advanced bladder cancer
    • Als AB, Dyrskjøt L, von der Maase H, et al., Emmprin and survivin predict response and survival following cisplatin-containing chemotherapy in patients with advanced bladder cancer. Clin Cancer Res 2007; 13 (15 part 1): 4407-4414.
    • (2007) Clin Cancer Res , vol.13 , Issue.15 PART 1 , pp. 4407-4414
    • Als, A.B.1    Dyrskjøt, L.2    Von Der Maase, H.3
  • 18
    • 33644867290 scopus 로고    scopus 로고
    • Defining molecular profiles of poor outcome in patients with invasive bladder cancer using oligonucleotide microarrays
    • Sanchez-Carbayo M, Socci ND, Lozano J, et al., Defining molecular profiles of poor outcome in patients with invasive bladder cancer using oligonucleotide microarrays. J Clin Oncol 2006; 24: 778-789.
    • (2006) J Clin Oncol , vol.24 , pp. 778-789
    • Sanchez-Carbayo, M.1    Socci, N.D.2    Lozano, J.3
  • 19
    • 69849115183 scopus 로고    scopus 로고
    • Generation of a concise gene panel for outcome prediction in urinary bladder cancer
    • Mitra AP, Pagliarulo V, Yang D, et al., Generation of a concise gene panel for outcome prediction in urinary bladder cancer. J Clin Oncol 2009; 27: 3929-3937.
    • (2009) J Clin Oncol , vol.27 , pp. 3929-3937
    • Mitra, A.P.1    Pagliarulo, V.2    Yang, D.3
  • 20
    • 33846469888 scopus 로고    scopus 로고
    • Use of combined apoptosis biomarkers for prediction of bladder cancer recurrence and mortality after radical cystectomy
    • Karam JA, Lotan Y, Karakiewicz PI, et al., Use of combined apoptosis biomarkers for prediction of bladder cancer recurrence and mortality after radical cystectomy. Lancet Oncol 2007; 8: 128-136.
    • (2007) Lancet Oncol , vol.8 , pp. 128-136
    • Karam, J.A.1    Lotan, Y.2    Karakiewicz, P.I.3
  • 21
    • 1842457693 scopus 로고    scopus 로고
    • P53, p21, pRB, and p16 expression predict clinical outcome in cystectomy with bladder cancer
    • Shariat SF, Tokunaga H, Zhou J, et al., p53, p21, pRB, and p16 expression predict clinical outcome in cystectomy with bladder cancer. J Clin Oncol 2004; 22: 1014-1024.
    • (2004) J Clin Oncol , vol.22 , pp. 1014-1024
    • Shariat, S.F.1    Tokunaga, H.2    Zhou, J.3
  • 22
    • 1542299243 scopus 로고    scopus 로고
    • Selective bladder preservation for muscle-invasive transitional cell carcinoma of the urinary bladder
    • Michaelson MD, Shipley WU, Heney NM, et al., Selective bladder preservation for muscle-invasive transitional cell carcinoma of the urinary bladder. Br J Cancer 2004; 90: 578-581.
    • (2004) Br J Cancer , vol.90 , pp. 578-581
    • Michaelson, M.D.1    Shipley, W.U.2    Heney, N.M.3
  • 23
    • 0021910302 scopus 로고
    • Preliminary results of M-VAC (methotrexate, vinblastine, doxorubicin and cisplatin) for transitional cell carcinoma of the urothelium
    • Sternberg CN, Yagoda A, Scher HI, et al., Preliminary results of M-VAC (methotrexate, vinblastine, doxorubicin and cisplatin) for transitional cell carcinoma of the urothelium. J Urol 1985; 133: 403-407.
    • (1985) J Urol , vol.133 , pp. 403-407
    • Sternberg, C.N.1    Yagoda, A.2    Scher, H.I.3
  • 24
    • 0033857218 scopus 로고    scopus 로고
    • Gemcitabine and cisplatin versus methotrexate, vinblastine, doxorubicin, and cisplatin in advanced or metastatic bladder cancer: Results of a large, randomized, multinational, multicenter, phase III study
    • Von der Maase H, Hansen SW, Roberts JT, et al., Gemcitabine and cisplatin versus methotrexate, vinblastine, doxorubicin, and cisplatin in advanced or metastatic bladder cancer: results of a large, randomized, multinational, multicenter, phase III study. J Clin Oncol 2000; 18: 3068-3077.
    • (2000) J Clin Oncol , vol.18 , pp. 3068-3077
    • Von Der Maase, H.1    Hansen, S.W.2    Roberts, J.T.3
  • 25
    • 36549023828 scopus 로고    scopus 로고
    • Randomized phase III study comparing paclitaxel/ cisplatin/gemcitabine and gemcitabine/cisplatin in patients with locally advanced or metastatic urothelial cancer without prior systemic therapy: EORTC30987/ Intergroup Study
    • Abstract 5030
    • Bellmunt J, von der Maase H, Mead GM, et al., Randomized phase III study comparing paclitaxel/ cisplatin/gemcitabine and gemcitabine/cisplatin in patients with locally advanced or metastatic urothelial cancer without prior systemic therapy: EORTC30987/ Intergroup Study. Proc Am Soc Clin Oncol 2007; 25:Abstract 5030.
    • (2007) Proc Am Soc Clin Oncol , vol.25
    • Bellmunt, J.1    Von Der Maase, H.2    Mead, G.M.3
  • 26
    • 61549118640 scopus 로고    scopus 로고
    • Randomised phase III trial of vinflunine plus best supportive care vs best supportive care alone as 2nd line therapy after a platinum-containing regimen in advanced transitional cell carcinoma of the urothelium
    • Abstract 5028
    • Bellmunt J, von der Maase H, Theodore C, et al., Randomised phase III trial of vinflunine plus best supportive care vs best supportive care alone as 2nd line therapy after a platinum-containing regimen in advanced transitional cell carcinoma of the urothelium. J Clin Oncol 2008; 26 (suppl 15S):Abstract 5028.
    • (2008) J Clin Oncol , vol.26 , Issue.SUPPL. 15S
    • Bellmunt, J.1    Von Der Maase, H.2    Theodore, C.3
  • 27
    • 0034068319 scopus 로고    scopus 로고
    • Antitumor effect and potentiation of cytotoxic drugs activity in human cancer cells by ZD-1839 (Iressa), an epidermal growth factor receptor-selective tyrosine kinase inhibitor
    • Ciardiello F, Caputo R, Bianco R, et al., Antitumor effect and potentiation of cytotoxic drugs activity in human cancer cells by ZD-1839 (Iressa), an epidermal growth factor receptor-selective tyrosine kinase inhibitor. Clin Cancer Res 2000; 6: 2053-2063.
    • (2000) Clin Cancer Res , vol.6 , pp. 2053-2063
    • Ciardiello, F.1    Caputo, R.2    Bianco, R.3
  • 28
    • 75149171017 scopus 로고    scopus 로고
    • Results of the Southwest Oncology Group phase II evaluation (study S0031) of ZD1839 for advanced transitional cell carcinoma of the urothelium
    • Petrylak DP, Tangen CM, Van Veldhuizen PJ Jr, et al., Results of the Southwest Oncology Group phase II evaluation (study S0031) of ZD1839 for advanced transitional cell carcinoma of the urothelium. BJU Int 2010; 105: 317-321.
    • (2010) BJU Int , vol.105 , pp. 317-321
    • Petrylak, D.P.1    Tangen, C.M.2    Van Veldhuizen, Jr.P.J.3
  • 29
    • 76649134077 scopus 로고    scopus 로고
    • Role of epithelial-to-mesenchymal transition (EMT) in drug sensitivity and metastasis in bladder cancer
    • McConkey DJ, Choi W, Marquis L, et al., Role of epithelial-to-mesenchymal transition (EMT) in drug sensitivity and metastasis in bladder cancer. Cancer Metastasis Rev 2009; 28: 335-344.
    • (2009) Cancer Metastasis Rev , vol.28 , pp. 335-344
    • McConkey, D.J.1    Choi, W.2    Marquis, L.3
  • 30
    • 77950474660 scopus 로고    scopus 로고
    • Phase II study of sunitinib in patients with metastatic urothelial cancer
    • Gallagher DJ, Milowsky MI, Gerst SR, et al., Phase II study of sunitinib in patients with metastatic urothelial cancer. J Clin Oncol 2010; 28: 1373-1379.
    • (2010) J Clin Oncol , vol.28 , pp. 1373-1379
    • Gallagher, D.J.1    Milowsky, M.I.2    Gerst, S.R.3
  • 31
    • 67649354223 scopus 로고    scopus 로고
    • Sunitinib malate is active against human urothelial carcinoma and enhances the activity of cisplatin in a preclinical model
    • Sonpavde G, Jian W, Liu H, et al., Sunitinib malate is active against human urothelial carcinoma and enhances the activity of cisplatin in a preclinical model. Urol Oncol 2009; 27: 391-399.
    • (2009) Urol Oncol , vol.27 , pp. 391-399
    • Sonpavde, G.1    Jian, W.2    Liu, H.3
  • 32
    • 78649649938 scopus 로고    scopus 로고
    • Phase II study of gemcitabine, cisplatin, and sunitinib in patients with advanced urothelial carcinoma
    • Abstract 276
    • Galsky MD, Sonpavde G, Hellerstedt BA, et al., Phase II study of gemcitabine, cisplatin, and sunitinib in patients with advanced urothelial carcinoma. ASCO Genitourinary Cancers Symposium 2010: Abstract 276.
    • (2010) ASCO Genitourinary Cancers Symposium
    • Galsky, M.D.1    Sonpavde, G.2    Hellerstedt, B.A.3
  • 33
    • 77956189149 scopus 로고    scopus 로고
    • A multicenter phase II study of cisplatin (C), gemcitabine (G), and bevacizumab (B) as first-line chemotherapy for metastatic urothelial carcinoma (UC): Hoosier Oncology Group GU-0475
    • Abstract 5018
    • Hahn NM, Stadler WM, Zon RT, et al., A multicenter phase II study of cisplatin (C), gemcitabine (G), and bevacizumab (B) as first-line chemotherapy for metastatic urothelial carcinoma (UC): Hoosier Oncology Group GU-0475. J Clin Oncol 2009; 27 (suppl 15S):Abstract 5018.
    • (2009) J Clin Oncol , vol.27 , Issue.SUPPL. 15S
    • Hahn, N.M.1    Stadler, W.M.2    Zon, R.T.3
  • 34
    • 0028051625 scopus 로고
    • Accumulation of nuclear p53 and tumor progression in bladder cancer
    • Esrig D, Elmajian D, Groshen S, et al., Accumulation of nuclear p53 and tumor progression in bladder cancer. N Engl J Med 1994; 331: 1259-1264.
    • (1994) N Engl J Med , vol.331 , pp. 1259-1264
    • Esrig, D.1    Elmajian, D.2    Groshen, S.3
  • 35
    • 0031012872 scopus 로고    scopus 로고
    • P53 and treatment of bladder cancer
    • Cote RJ, Esrig D, Groshen S, et al., p53 and treatment of bladder cancer. Nature 1997; 385: 123-125.
    • (1997) Nature , vol.385 , pp. 123-125
    • Cote, R.J.1    Esrig, D.2    Groshen, S.3
  • 36
    • 77954001189 scopus 로고    scopus 로고
    • Randomized trial of p53 targeted adjuvant therapy for patients with organ-confined node-negative urothelial bladder cancer
    • Abstract 5017
    • Stadler WM, Lerner SP, Groshen S, et al., Randomized trial of p53 targeted adjuvant therapy for patients with organ-confined node-negative urothelial bladder cancer. J Clin Oncol 2009; 27 (suppl 15S):Abstract 5017.
    • (2009) J Clin Oncol , vol.27 , Issue.SUPPL. 15S
    • Stadler, W.M.1    Lerner, S.P.2    Groshen, S.3
  • 37
    • 33847681504 scopus 로고    scopus 로고
    • Gene expression of ERCC1 as a novel prognostic marker in advanced bladder cancer patients receiving cisplatin-based chemotherapy
    • Bellmunt J, Paz-Ares L, Cuello M, et al., Gene expression of ERCC1 as a novel prognostic marker in advanced bladder cancer patients receiving cisplatin-based chemotherapy. Ann Oncol 2007; 18: 522-528.
    • (2007) Ann Oncol , vol.18 , pp. 522-528
    • Bellmunt, J.1    Paz-Ares, L.2    Cuello, M.3
  • 38
    • 33751345359 scopus 로고    scopus 로고
    • Validation study of the prediction system for clinical response of M-VAC neoadjuvant chemotherapy
    • Takata R, Katagiri T, Kanehira M, et al., Validation study of the prediction system for clinical response of M-VAC neoadjuvant chemotherapy. Cancer Sci 2007; 98: 113-117.
    • (2007) Cancer Sci , vol.98 , pp. 113-117
    • Takata, R.1    Katagiri, T.2    Kanehira, M.3
  • 39
    • 20244368343 scopus 로고    scopus 로고
    • Predicting response to methotrexate, vinblastine, doxorubicin, and cisplatin neoadjuvant chemotherapy for bladder cancers through genome-wide gene expression profiling
    • Takata R, Katagiri T, Kanehira M, et al., Predicting response to methotrexate, vinblastine, doxorubicin, and cisplatin neoadjuvant chemotherapy for bladder cancers through genome-wide gene expression profiling. Clin Cancer Res 2005; 11: 2625-2636.
    • (2005) Clin Cancer Res , vol.11 , pp. 2625-2636
    • Takata, R.1    Katagiri, T.2    Kanehira, M.3
  • 40
    • 70350536600 scopus 로고    scopus 로고
    • Concordant gene expression signatures predict clinical outcomes of cancer patients undergoing systemic therapy
    • Williams PD, Cheon S, Havaleshko DM, et al., Concordant gene expression signatures predict clinical outcomes of cancer patients undergoing systemic therapy. Cancer Res 2009; 69: 8302-8309.
    • (2009) Cancer Res , vol.69 , pp. 8302-8309
    • Williams, P.D.1    Cheon, S.2    Havaleshko, D.M.3
  • 41
    • 67649579849 scopus 로고    scopus 로고
    • A single-arm, multicenter, open-label phase 2 study of lapatinib as the second-line treatment of patients with locally advanced or metastatic transitional cell carcinoma
    • Wülfing C, Machiels JP, Richel DJ, et al., A single-arm, multicenter, open-label phase 2 study of lapatinib as the second-line treatment of patients with locally advanced or metastatic transitional cell carcinoma. Cancer 2009; 115: 2881-2890.
    • (2009) Cancer , vol.115 , pp. 2881-2890
    • Wülfing, C.1    MacHiels, J.P.2    Richel, D.J.3
  • 42
    • 77952243964 scopus 로고    scopus 로고
    • Target-specific randomized discontinuation trial design: A novel approach in molecular therapeutics
    • Galsky MD, Zaks T, Hassani H, et al., Target-specific randomized discontinuation trial design: a novel approach in molecular therapeutics. Invest New Drugs 2010; 28: 194-198.
    • (2010) Invest New Drugs , vol.28 , pp. 194-198
    • Galsky, M.D.1    Zaks, T.2    Hassani, H.3
  • 43
    • 77951206397 scopus 로고    scopus 로고
    • Target-specific, histology-independent, randomized discontinuation study of lapatinib in patients with HER2-amplified solid tumors
    • Abstract 3541
    • Galsky MD, Von Hoff DD, Neubauer M, et al., Target-specific, histology-independent, randomized discontinuation study of lapatinib in patients with HER2-amplified solid tumors. J Clin Oncol 2009; 27 (suppl 15S):Abstract 3541.
    • (2009) J Clin Oncol , vol.27 , Issue.SUPPL. 15S
    • Galsky, M.D.1    Von Hoff, D.D.2    Neubauer, M.3
  • 44
    • 77953434938 scopus 로고    scopus 로고
    • A phase II trial of neoadjuvant erlotinib in patients with muscle-invasive bladder cancer undergoing radical cystectomy: Clinical and pathological results
    • Pruthi RS, Nielsen M, Heathcote S, et al., A phase II trial of neoadjuvant erlotinib in patients with muscle-invasive bladder cancer undergoing radical cystectomy: clinical and pathological results. BJU Int 2010; 106: 349-356.
    • (2010) BJU Int , vol.106 , pp. 349-356
    • Pruthi, R.S.1    Nielsen, M.2    Heathcote, S.3
  • 45
    • 77952174698 scopus 로고    scopus 로고
    • Dasatinib is preclinically active against Src-overexpressing human transitional cell carcinoma of the urothelium with activated Src signaling
    • Levitt JM, Yamashita H, Jian W, et al., Dasatinib is preclinically active against Src-overexpressing human transitional cell carcinoma of the urothelium with activated Src signaling. Mol Cancer Ther 2010; 9: 1128-1135.
    • (2010) Mol Cancer Ther , vol.9 , pp. 1128-1135
    • Levitt, J.M.1    Yamashita, H.2    Jian, W.3
  • 46
    • 0026625220 scopus 로고
    • A randomized comparison of cisplatin alone or in combination with methotrexate, vinblastine, and doxorubicin in patients with metastatic urothelial carcinoma: A cooperative group study
    • Loehrer PJ Sr, Einhorn LH, Elson PJ, et al., A randomized comparison of cisplatin alone or in combination with methotrexate, vinblastine, and doxorubicin in patients with metastatic urothelial carcinoma: a cooperative group study. J Clin Oncol 1992; 10: 1066-1073.
    • (1992) J Clin Oncol , vol.10 , pp. 1066-1073
    • Loehrer, Sr.P.J.1    Einhorn, L.H.2    Elson, P.J.3
  • 47
    • 0025297496 scopus 로고
    • A prospective randomized trial comparing MVAC and CISCA chemotherapy for patients with metastatic urothelial tumors
    • Logothetis CJ, Dexeus FH, Finn L, et al., A prospective randomized trial comparing MVAC and CISCA chemotherapy for patients with metastatic urothelial tumors. J Clin Oncol 1990; 8: 1050-1055.
    • (1990) J Clin Oncol , vol.8 , pp. 1050-1055
    • Logothetis, C.J.1    Dexeus, F.H.2    Finn, L.3
  • 48
    • 0036498768 scopus 로고    scopus 로고
    • Phase III trial of fluorouracil, interferon alpha-2b, and cisplatin versus methotrexate, vinblastine, doxorubicin, and cisplatin in metastatic or unresectable urothelial cancer
    • Siefker-Radtke AO, Millikan RE, Tu SM, et al., Phase III trial of fluorouracil, interferon alpha-2b, and cisplatin versus methotrexate, vinblastine, doxorubicin, and cisplatin in metastatic or unresectable urothelial cancer. J Clin Oncol 2002; 20: 1361-1367.
    • (2002) J Clin Oncol , vol.20 , pp. 1361-1367
    • Siefker-Radtke, A.O.1    Millikan, R.E.2    Tu, S.M.3
  • 49
    • 0035873915 scopus 로고    scopus 로고
    • Randomized phase III trial of high-dose-intensity methotrexate, vinblastine, doxorubicin, and cisplatin (MVAC) chemotherapy and recombinant human granulocyte colony-stimulating factor versus classic MVAC in advanced urothelial tract tumors: European Organization for Research and Treatment of Cancer Protocol no. 30924
    • Sternberg CN, de Mulder PH, Schornagel JH, et al., Randomized phase III trial of high-dose-intensity methotrexate, vinblastine, doxorubicin, and cisplatin (MVAC) chemotherapy and recombinant human granulocyte colony-stimulating factor versus classic MVAC in advanced urothelial tract tumors: European Organization for Research and Treatment of Cancer Protocol no. 30924. J Clin Oncol 2001; 19: 2638-2646.
    • (2001) J Clin Oncol , vol.19 , pp. 2638-2646
    • Sternberg, C.N.1    De Mulder, P.H.2    Schornagel, J.H.3
  • 50
    • 1342268941 scopus 로고    scopus 로고
    • Docetaxel and cisplatin with granulocyte colony-stimulating factor (G-CSF) versus MVAC with G-CSF in advanced urothelial carcinoma: A multicenter, randomized, phase III study from the Hellenic Cooperative Oncology Group
    • Bamias A, Aravantinos G, Deliveliotis C, et al., Docetaxel and cisplatin with granulocyte colony-stimulating factor (G-CSF) versus MVAC with G-CSF in advanced urothelial carcinoma: a multicenter, randomized, phase III study from the Hellenic Cooperative Oncology Group. J Clin Oncol 2004; 22: 220-228.
    • (2004) J Clin Oncol , vol.22 , pp. 220-228
    • Bamias, A.1    Aravantinos, G.2    Deliveliotis, C.3
  • 51
    • 1842477465 scopus 로고    scopus 로고
    • Phase III trial of methotrexate, vinblastine, doxorubicin, and cisplatin versus carboplatin and paclitaxel in patients with advanced carcinoma of the urothelium
    • Dreicer R, Manola J, Roth BJ, et al., Phase III trial of methotrexate, vinblastine, doxorubicin, and cisplatin versus carboplatin and paclitaxel in patients with advanced carcinoma of the urothelium. Cancer 2004; 100: 1639-1645.
    • (2004) Cancer , vol.100 , pp. 1639-1645
    • Dreicer, R.1    Manola, J.2    Roth, B.J.3
  • 52
    • 0037083580 scopus 로고    scopus 로고
    • Phase II trial of weekly paclitaxel in patients with previously treated advanced urothelial cancer
    • Vaughn DJ, Broome CM, Hussain M, et al., Phase II trial of weekly paclitaxel in patients with previously treated advanced urothelial cancer. J Clin Oncol 2002; 20: 937-940.
    • (2002) J Clin Oncol , vol.20 , pp. 937-940
    • Vaughn, D.J.1    Broome, C.M.2    Hussain, M.3
  • 54
    • 0031017367 scopus 로고    scopus 로고
    • Eastern Cooperative Oncology Group phase II trial of ifosfamide in the treatment of previously treated advanced urothelial carcinoma
    • Witte RS, Elson P, Bono B, et al., Eastern Cooperative Oncology Group phase II trial of ifosfamide in the treatment of previously treated advanced urothelial carcinoma. J Clin Oncol 1997; 15: 589-593.
    • (1997) J Clin Oncol , vol.15 , pp. 589-593
    • Witte, R.S.1    Elson, P.2    Bono, B.3
  • 55
    • 0032127772 scopus 로고    scopus 로고
    • A phase II study of gemcitabine in patients with transitional cell carcinoma of the urinary tract previously treated with platinum. Italian Co-operative Group on Bladder Cancer
    • Lorusso V, Pollera CF, Antimi M, et al., A phase II study of gemcitabine in patients with transitional cell carcinoma of the urinary tract previously treated with platinum. Italian Co-operative Group on Bladder Cancer. Eur J Cancer 1998; 34: 1208-1212.
    • (1998) Eur J Cancer , vol.34 , pp. 1208-1212
    • Lorusso, V.1    Pollera, C.F.2    Antimi, M.3
  • 56
    • 26444543202 scopus 로고    scopus 로고
    • Phase II trial of carboplatin and paclitaxel in cisplatin-pretreated advanced transitional cell carcinoma: A Southwest Oncology Group study
    • Vaishampayan UN, Faulkner JR, Small EJ, et al., Phase II trial of carboplatin and paclitaxel in cisplatin-pretreated advanced transitional cell carcinoma: a Southwest Oncology Group study. Cancer 2005; 104: 1627-1632.
    • (2005) Cancer , vol.104 , pp. 1627-1632
    • Vaishampayan, U.N.1    Faulkner, J.R.2    Small, E.J.3
  • 57
    • 33646844469 scopus 로고    scopus 로고
    • A phase II study of vinflunine in bladder cancer patients progressing after first-line platinum-containing regimen
    • Culine S, Theodore C, De Santis M, et al., A phase II study of vinflunine in bladder cancer patients progressing after first-line platinum-containing regimen. Br J Cancer 2006; 94: 1395-1401.
    • (2006) Br J Cancer , vol.94 , pp. 1395-1401
    • Culine, S.1    Theodore, C.2    De Santis, M.3
  • 58
    • 34248641378 scopus 로고    scopus 로고
    • Phase II trial of pemetrexed as second-line therapy in patients with metastatic urothelial carcinoma
    • Galsky MD, Mironov S, Iasonos A, et al., Phase II trial of pemetrexed as second-line therapy in patients with metastatic urothelial carcinoma. Invest New Drugs 2007; 25: 265-270.
    • (2007) Invest New Drugs , vol.25 , pp. 265-270
    • Galsky, M.D.1    Mironov, S.2    Iasonos, A.3
  • 59
    • 33746851717 scopus 로고    scopus 로고
    • Phase II study of pemetrexed for second-line treatment of transitional cell cancer of the urothelium
    • Sweeney CJ, Roth BJ, Kabbinavar FF, et al., Phase II study of pemetrexed for second-line treatment of transitional cell cancer of the urothelium. J Clin Oncol 2006; 24: 3451-3457.
    • (2006) J Clin Oncol , vol.24 , pp. 3451-3457
    • Sweeney, C.J.1    Roth, B.J.2    Kabbinavar, F.F.3


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