메뉴 건너뛰기




Volumn 71, Issue 7, 2010, Pages 383-394

Metabolic limitations of the use of nucleoside analogs in cancer therapy may be overcome by application of nanoparticles as drug carriers: A review

Author keywords

cytarabine; drug resistance; gemcitabine; nanoparticles; nucleoside analogs

Indexed keywords

ADENOSINE; ALBUMIN; AMPHOTERICIN B LIPID COMPLEX; ASPARAGINASE MACROGOL; CLADRIBINE; CLOFARABINE; CYTARABINE; CYTIDINE; DAUNORUBICIN; DENDRIMER; DOXORUBICIN; DRUG CARRIER; FLUDARABINE; FLUOROURACIL; GEMCITABINE; LIPOSOME; MERCAPTOPURINE; METHOTREXATE; MITOXANTRONE; NANOPARTICLE; NANOSPHERE; NUCLEOSIDE ANALOG; PACLITAXEL; PEGINTERFERON ALPHA2A; POLYMER; PROPOFOL;

EID: 78649661353     PISSN: 02724391     EISSN: 10982299     Source Type: Journal    
DOI: 10.1002/ddr.20390     Document Type: Review
Times cited : (7)

References (62)
  • 1
    • 0026692103 scopus 로고
    • Stealth liposomes: An improved sustained release system for 1-beta-D-arabinofuranosylcytosine
    • Allen TM, Mehra T, Hansen C, Chin YC,. 1992. Stealth liposomes: an improved sustained release system for 1-beta-D-arabinofuranosylcytosine. Cancer Res 52: 2431-2439.
    • (1992) Cancer Res , vol.52 , pp. 2431-2439
    • Allen, T.M.1    Mehra, T.2    Hansen, C.3    Chin, Y.C.4
  • 2
    • 33845430694 scopus 로고    scopus 로고
    • Pharmacology of drugs formulated with DepoFoam: A sustained release drug delivery system for parenteral administration using multivesicular liposome technology
    • Angst MS, Drover DR,. 2006. Pharmacology of drugs formulated with DepoFoam: a sustained release drug delivery system for parenteral administration using multivesicular liposome technology. Clin Pharmacokinet 45: 1153-1176.
    • (2006) Clin Pharmacokinet , vol.45 , pp. 1153-1176
    • Angst, M.S.1    Drover, D.R.2
  • 4
    • 67650178791 scopus 로고    scopus 로고
    • Pharmacokinet of CPX-351 (cytarabine/daunorubicin HCl) liposome injection in the mouse
    • Bayne WF, Mayer LD, Swenson CE,. 2009. Pharmacokinet of CPX-351 (cytarabine/daunorubicin HCl) liposome injection in the mouse. J Pharm Sci 98: 2540-2548.
    • (2009) J Pharm Sci , vol.98 , pp. 2540-2548
    • Bayne, W.F.1    Mayer, L.D.2    Swenson, C.E.3
  • 5
    • 70350571637 scopus 로고    scopus 로고
    • Dendrimers: Analytical characterization and applications
    • Biricova V, Laznickova A,. 2009. Dendrimers: analytical characterization and applications. Bioorg Chem 37: 185-192.
    • (2009) Bioorg Chem , vol.37 , pp. 185-192
    • Biricova, V.1    Laznickova, A.2
  • 6
    • 0024595925 scopus 로고
    • Clinical pharmacology of 5-fluorouracil
    • Diasio RB, Harris BE,. 1989. Clinical pharmacology of 5-fluorouracil. Clin Pharmacokinet 16: 215-237.
    • (1989) Clin Pharmacokinet , vol.16 , pp. 215-237
    • Diasio, R.B.1    Harris, B.E.2
  • 7
    • 70450196798 scopus 로고    scopus 로고
    • Liposome-encapsulated anticancer drugs: Still waiting for the magic bullet?
    • Fanciullino R, Ciccolini J,. 2009. Liposome-encapsulated anticancer drugs: still waiting for the magic bullet? Curr Med Chem 16: 4361-4371.
    • (2009) Curr Med Chem , vol.16 , pp. 4361-4371
    • Fanciullino, R.1    Ciccolini, J.2
  • 8
    • 64049086772 scopus 로고    scopus 로고
    • Nanoparticles in cellular drug delivery
    • Faraji AH, Wipf P,. 2009. Nanoparticles in cellular drug delivery. Bioorg Med Chem 17: 2950-2962.
    • (2009) Bioorg Med Chem , vol.17 , pp. 2950-2962
    • Faraji, A.H.1    Wipf, P.2
  • 9
    • 67650123823 scopus 로고    scopus 로고
    • Phase i study of a liposomal carrier (CPX-351) containing an optimized synergistic fixed molar ratio of cytarabine and daunorubicin in advanced leukemias and myelodysplastic syndromes
    • Feldman E, Lancet J, Kolitz JE, Assianti E, Swenson C, Mayer L, Janoff A, Louie A,. 2007. Phase I study of a liposomal carrier (CPX-351) containing an optimized synergistic fixed molar ratio of cytarabine and daunorubicin in advanced leukemias and myelodysplastic syndromes. Am Soc Hematol Ann Meet Blood 110: 909.
    • (2007) Am Soc Hematol Ann Meet Blood , vol.110 , pp. 909
    • Feldman, E.1    Lancet, J.2    Kolitz, J.E.3    Assianti, E.4    Swenson, C.5    Mayer, L.6    Janoff, A.7    Louie, A.8
  • 10
    • 0034994444 scopus 로고    scopus 로고
    • Nucleoside analogues: Mechanisms of drug resistance and reversal strategies
    • Galmarini CM, Mackey JR, Dumontet C,. 2001. Nucleoside analogues: mechanisms of drug resistance and reversal strategies. Leukemia 15: 875-890.
    • (2001) Leukemia , vol.15 , pp. 875-890
    • Galmarini, C.M.1    MacKey, J.R.2    Dumontet, C.3
  • 11
    • 0036636579 scopus 로고    scopus 로고
    • Nucleoside analogues and nucleobases in cancer treatment
    • Galmarini CM, Mackey JR, Dumontet Ch,. 2002. Nucleoside analogues and nucleobases in cancer treatment. Lancet Oncol 3: 415-424.
    • (2002) Lancet Oncol , vol.3 , pp. 415-424
    • Galmarini, C.M.1    MacKey, J.R.2    Dumontet, C.3
  • 12
    • 55749093075 scopus 로고    scopus 로고
    • Polymeric nanogels containing the triphosphate form of cytotoxic nucleoside analogues show antitumor activity against breast and colorectal cancer cell lines
    • Galmarini CM, Warren G, Kohli E, Zeman A, Mitin A, Vinogradov SV,. 2008. Polymeric nanogels containing the triphosphate form of cytotoxic nucleoside analogues show antitumor activity against breast and colorectal cancer cell lines. Mol Cancer Ther 7: 3373-3380.
    • (2008) Mol Cancer Ther , vol.7 , pp. 3373-3380
    • Galmarini, C.M.1    Warren, G.2    Kohli, E.3    Zeman, A.4    Mitin, A.5    Vinogradov, S.V.6
  • 13
    • 0036204648 scopus 로고    scopus 로고
    • Cellular and clinical pharmacology of fludarabine
    • Gandhi V, Plunkett W,. 2002. Cellular and clinical pharmacology of fludarabine. Clin Pharmacokinet 41: 93-103.
    • (2002) Clin Pharmacokinet , vol.41 , pp. 93-103
    • Gandhi, V.1    Plunkett, W.2
  • 14
    • 41549123975 scopus 로고    scopus 로고
    • Nanoparticles for drug delivery: The need for precision in reporting particle size parameters
    • Gaumet M, Vargas A, Gurny R, Delie F,. 2008. Nanoparticles for drug delivery: the need for precision in reporting particle size parameters. Eur J Pharm Biopharm 69: 1-9.
    • (2008) Eur J Pharm Biopharm , vol.69 , pp. 1-9
    • Gaumet, M.1    Vargas, A.2    Gurny, R.3    Delie, F.4
  • 15
    • 18844370132 scopus 로고    scopus 로고
    • Biological evaluation of polyester dendrimer: Poly(ethylene oxide) "bow-tie" hybrids with tunable molecular weight and architecture
    • Gillies ER, Dy E, Frechet JMJ, Szoka FC,. 2005. Biological evaluation of polyester dendrimer: poly(ethylene oxide) "bow-tie" hybrids with tunable molecular weight and architecture. Mol Pharm 2: 129-138.
    • (2005) Mol Pharm , vol.2 , pp. 129-138
    • Gillies, E.R.1    Dy, E.2    Frechet, J.M.J.3    Szoka, F.C.4
  • 18
    • 37649010361 scopus 로고    scopus 로고
    • Nanoparticles for drug delivery in cancer treatment
    • Haley B, Frenkel E,. 2008. Nanoparticles for drug delivery in cancer treatment. Urol Oncol 26: 57-64.
    • (2008) Urol Oncol , vol.26 , pp. 57-64
    • Haley, B.1    Frenkel, E.2
  • 19
    • 17844380498 scopus 로고    scopus 로고
    • Pegylation: A novel process for modifying pharmacokinetics
    • Harris JM, Martin NE, Modi M,. 2001. Pegylation: a novel process for modifying pharmacokinetics. Clin Pharmacokinet 40: 539-551.
    • (2001) Clin Pharmacokinet , vol.40 , pp. 539-551
    • Harris, J.M.1    Martin, N.E.2    Modi, M.3
  • 20
    • 33750039957 scopus 로고    scopus 로고
    • Polymer-based nanoparticles for the delivery of nucleoside analogues
    • Hillaireau H, Le Doan T, Couvreur P,. 2006. Polymer-based nanoparticles for the delivery of nucleoside analogues. J Nanosci Nanotechnol 6: 2608-2617.
    • (2006) J Nanosci Nanotechnol , vol.6 , pp. 2608-2617
    • Hillaireau, H.1    Le Doan, T.2    Couvreur, P.3
  • 21
    • 35848960127 scopus 로고    scopus 로고
    • Review of recent studies on resistance to cytotoxic deoxynucleoside analogues
    • Jordheim LP, Dumontet C,. 2007. Review of recent studies on resistance to cytotoxic deoxynucleoside analogues. Biochim Biophys Acta 1776: 138-159.
    • (2007) Biochim Biophys Acta , vol.1776 , pp. 138-159
    • Jordheim, L.P.1    Dumontet, C.2
  • 22
    • 70349798806 scopus 로고    scopus 로고
    • Antitumor activity of EGFR targeted pH-sensitive immunoliposomes encapsulating gemcitabine in A549 xenograft nude mice
    • Kim I-Y, Kang Y-S, Lee DS, Park H-J, Choi E-K, Oh Y-K, Son H-J, Kim J-S,. 2009. Antitumor activity of EGFR targeted pH-sensitive immunoliposomes encapsulating gemcitabine in A549 xenograft nude mice. J Control Release 140: 55-60.
    • (2009) J Control Release , vol.140 , pp. 55-60
    • Kim, I.-Y.1    Kang, Y.-S.2    Lee, D.S.3    Park, H.-J.4    Choi, E.-K.5    Oh, Y.-K.6    Son, H.-J.7    Kim, J.-S.8
  • 23
    • 0035229874 scopus 로고    scopus 로고
    • Dendrimers: Properties and applications
    • Klajnert B, Bryszewska M,. 2001. Dendrimers: properties and applications. Acta Biochim Pol 48: 199-208.
    • (2001) Acta Biochim Pol , vol.48 , pp. 199-208
    • Klajnert, B.1    Bryszewska, M.2
  • 24
    • 53849139796 scopus 로고    scopus 로고
    • The influence of densely organized maltose shells on the biological properties of poly(propylene imine) dendrimers: New effects dependent on hydrogen bonding
    • Klajnert B, Appelhans D, Komber H, Morgner N, Schwarz S, Richter S, Brutschy B, Voit B,. 2008. The influence of densely organized maltose shells on the biological properties of poly(propylene imine) dendrimers: new effects dependent on hydrogen bonding. Chemistry 14: 7030-7041.
    • (2008) Chemistry , vol.14 , pp. 7030-7041
    • Klajnert, B.1    Appelhans, D.2    Komber, H.3    Morgner, N.4    Schwarz, S.5    Richter, S.6    Brutschy, B.7    Voit, B.8
  • 25
    • 70449526181 scopus 로고    scopus 로고
    • Influence of dendrimer generation and polyethylene glycol length on the biodistribution of PEGylated dendrimers
    • Kojima C, Regino C, Umeda Y, Kobayashi H, Kono K,. 2010. Influence of dendrimer generation and polyethylene glycol length on the biodistribution of PEGylated dendrimers. Int J Pharm 383: 293-296.
    • (2010) Int J Pharm , vol.383 , pp. 293-296
    • Kojima, C.1    Regino, C.2    Umeda, Y.3    Kobayashi, H.4    Kono, K.5
  • 27
  • 29
    • 0033350776 scopus 로고    scopus 로고
    • A new class of biodegradable thermosensitive polymers. 2. Hydrolytic properties and salt effect on the lower critical solution temperature of poly(organophosphazenes) with methoxypoly(ethylene glycol) and amino acid esters as side groups
    • Lee SB, Song SC, Jin JI, Sohn YS,. 1999. A new class of biodegradable thermosensitive polymers. 2. Hydrolytic properties and salt effect on the lower critical solution temperature of poly(organophosphazenes) with methoxypoly(ethylene glycol) and amino acid esters as side groups. Macromolecules 32: 7820-7827.
    • (1999) Macromolecules , vol.32 , pp. 7820-7827
    • Lee, S.B.1    Song, S.C.2    Jin, J.I.3    Sohn, Y.S.4
  • 30
    • 67649484511 scopus 로고    scopus 로고
    • Injectable and thermosensitive poly(organophosphazene)hydrogels for a 5-fluorouracil delivery
    • Lee SM, Chun ChJ, Heo JY, Song SCh,. 2009. Injectable and thermosensitive poly(organophosphazene)hydrogels for a 5-fluorouracil delivery. J Appl Polymer Sci 113: 3831-3839.
    • (2009) J Appl Polymer Sci , vol.113 , pp. 3831-3839
    • Lee, S.M.1    Chj, C.2    Heo, J.Y.3    Sch, S.4
  • 31
    • 42949174825 scopus 로고    scopus 로고
    • Prodrugs of nucleoside analogues for improved oral absorption and tissue targeting
    • Li F, Maag H, Alfredson T,. 2008. Prodrugs of nucleoside analogues for improved oral absorption and tissue targeting. J Pharm Sci 97: 1109-1134.
    • (2008) J Pharm Sci , vol.97 , pp. 1109-1134
    • Li, F.1    Maag, H.2    Alfredson, T.3
  • 32
    • 70449672769 scopus 로고    scopus 로고
    • Folate-conjugated micelles and their folate-receptor-mediated endocytosis
    • Lu T, Sun J, Chen X, Zhang P, Jing X,. 2009. Folate-conjugated micelles and their folate-receptor-mediated endocytosis. Macromol Biosci 9: 1059-1068.
    • (2009) Macromol Biosci , vol.9 , pp. 1059-1068
    • Lu, T.1    Sun, J.2    Chen, X.3    Zhang, P.4    Jing, X.5
  • 33
    • 0000398353 scopus 로고    scopus 로고
    • Nucleoside transport and its significance for anticancer drug resistance
    • Mackey JR, Baldwin SA, Young JD, Cass CE,. 1998. Nucleoside transport and its significance for anticancer drug resistance. Drug Resist Updat 1: 310-324.
    • (1998) Drug Resist Updat , vol.1 , pp. 310-324
    • MacKey, J.R.1    Baldwin, S.A.2    Young, J.D.3    Cass, C.E.4
  • 34
    • 70350292588 scopus 로고    scopus 로고
    • Liposomes and nanoparticles: Nanosized vehicles for drug delivery in cancer
    • Malam Y, Loizidou M, Seifalian AM,. 2009. Liposomes and nanoparticles: nanosized vehicles for drug delivery in cancer. Trends Pharmacol Sci 30: 592-599.
    • (2009) Trends Pharmacol Sci , vol.30 , pp. 592-599
    • Malam, Y.1    Loizidou, M.2    Seifalian, A.M.3
  • 35
    • 0037437762 scopus 로고    scopus 로고
    • Down-regulation of deoxycytidine kinase in human leukemic cell lines resistant to cladribine and clofarabine and increased ribonucleotide reductase activity contributes to fludarabine resistance
    • MÅnsson E, Flordal E, Liliemark J, Spasokoukotskaja T, Elford H, Lagercrantz S, Eriksson S, Albertioni F,. 2003. Down-regulation of deoxycytidine kinase in human leukemic cell lines resistant to cladribine and clofarabine and increased ribonucleotide reductase activity contributes to fludarabine resistance. Biochem Pharmacol 65: 237-247.
    • (2003) Biochem Pharmacol , vol.65 , pp. 237-247
    • Månsson, E.1    Flordal, E.2    Liliemark, J.3    Spasokoukotskaja, T.4    Elford, H.5    Lagercrantz, S.6    Eriksson, S.7    Albertioni, F.8
  • 36
    • 67650690627 scopus 로고    scopus 로고
    • Dendrimers as carriers for delivery of chemotherapeutic agents
    • Medina SH, El-Sayed MEH,. 2009. Dendrimers as carriers for delivery of chemotherapeutic agents. Chem Rev 109: 3141-3157.
    • (2009) Chem Rev , vol.109 , pp. 3141-3157
    • Medina, S.H.1    El-Sayed, M.E.H.2
  • 38
    • 72449153806 scopus 로고    scopus 로고
    • Polymer-based nanocapsules for drug delivery
    • Mora-Huertas CE, Fessi H, Elaissari A,. 2009. Polymer-based nanocapsules for drug delivery. Int J Pharm 385: 113-142.
    • (2009) Int J Pharm , vol.385 , pp. 113-142
    • Mora-Huertas, C.E.1    Fessi, H.2    Elaissari, A.3
  • 40
    • 20044396385 scopus 로고    scopus 로고
    • Reduction of drug toxicity using dendrimers based on melamine
    • Neerman MF, Chen HT, Parrish AR, Simanek EE,. 2004. Reduction of drug toxicity using dendrimers based on melamine. Mol Pharm 1: 390-393.
    • (2004) Mol Pharm , vol.1 , pp. 390-393
    • Neerman, M.F.1    Chen, H.T.2    Parrish, A.R.3    Simanek, E.E.4
  • 41
    • 11144357506 scopus 로고    scopus 로고
    • Reduced cardiotoxicity and comparable efficacy in a phase III trial of pegylated liposomal doxorubicin HCl (CAELYX/Doxil) versus conventional doxorubicin for first-line treatment of metastatic breast cancer
    • O'Brien ME, Wigler N, Inbar M, Rosso R, Grischke E, Santoro A, Catane R, Kieback DG, Tomczak P, Ackland SP, Orlandi F, Mellars L, Alland L, Tendler C, CAELYX Breast Cancer Study Group,. 2004. Reduced cardiotoxicity and comparable efficacy in a phase III trial of pegylated liposomal doxorubicin HCl (CAELYX/Doxil) versus conventional doxorubicin for first-line treatment of metastatic breast cancer. Ann Oncol 15: 440-449.
    • (2004) Ann Oncol , vol.15 , pp. 440-449
    • O'Brien, M.E.1    Wigler, N.2    Inbar, M.3    Rosso, R.4    Grischke, E.5    Santoro, A.6    Catane, R.7    Kieback, D.G.8    Tomczak, P.9    Ackland, S.P.10    Orlandi, F.11    Mellars, L.12    Alland, L.13    Tendler, C.14
  • 42
    • 0344109583 scopus 로고    scopus 로고
    • Efficacy of intravenous continuous infusion of fluorouracil compared with bolus administration in advanced colorectal cancer
    • Piedbois P,. 1998. Efficacy of intravenous continuous infusion of fluorouracil compared with bolus administration in advanced colorectal cancer. Meta-Anal Group Cancer Clin Oncol 16: 301-308.
    • (1998) Meta-Anal Group Cancer Clin Oncol , vol.16 , pp. 301-308
    • Piedbois, P.1
  • 43
    • 33746729726 scopus 로고    scopus 로고
    • Simultaneous sustained release of fludarabine monophosphate and Gd-DTPA from an interstitial liposome depot in rats: Potential for indirect monitoring of drug release by magnetic resonance imaging
    • Port RE, Schuster C, Port CR, Bachert P,. 2006. Simultaneous sustained release of fludarabine monophosphate and Gd-DTPA from an interstitial liposome depot in rats: potential for indirect monitoring of drug release by magnetic resonance imaging. Cancer Chemother Pharmacol 58: 607-617.
    • (2006) Cancer Chemother Pharmacol , vol.58 , pp. 607-617
    • Port, R.E.1    Schuster, C.2    Port, C.R.3    Bachert, P.4
  • 44
    • 14344252720 scopus 로고    scopus 로고
    • Therapy of chronic lymphocytic leukemia with purine analogs and monoclonal antibodies
    • DOI 10.1016/j.transci.2004.10.004
    • Robak T,. 2005. Therapy of chronic lymphocytic leukemia with purine analogs and monoclonal antibodies. Transfus Apher Sci 32: 33-44. (Pubitemid 40292815)
    • (2005) Transfusion and Apheresis Science , vol.32 , Issue.1 , pp. 33-44
    • Robak, T.1
  • 45
    • 70350502604 scopus 로고    scopus 로고
    • Recent progress towards development of effective systemic chemotherapy for the treatment of malignant brain tumors
    • Sarin H,. 2009. Recent progress towards development of effective systemic chemotherapy for the treatment of malignant brain tumors. J Transl Med 7: 77.
    • (2009) J Transl Med , vol.7 , pp. 77
    • Sarin, H.1
  • 47
    • 0030795298 scopus 로고    scopus 로고
    • Liposomes in drug delivery: Progress and limitations
    • Sharma A, Sharma US,. 1997. Liposomes in drug delivery: progress and limitations. Int J Pharm 154: 123-140.
    • (1997) Int J Pharm , vol.154 , pp. 123-140
    • Sharma, A.1    Sharma, U.S.2
  • 48
    • 34648825412 scopus 로고    scopus 로고
    • Encapsulation of gemcitabine lipophilic derivatives into polycyanoacrylate nanospheres and nanocapsules
    • Stella B, Arpicco S, Rocco F, Marsaud V, Renoir JM, Cattel L, Couvreur P,. 2007. Encapsulation of gemcitabine lipophilic derivatives into polycyanoacrylate nanospheres and nanocapsules. Int J Pharm 344: 71-77.
    • (2007) Int J Pharm , vol.344 , pp. 71-77
    • Stella, B.1    Arpicco, S.2    Rocco, F.3    Marsaud, V.4    Renoir, J.M.5    Cattel, L.6    Couvreur, P.7
  • 49
    • 60749099362 scopus 로고    scopus 로고
    • Dendrimers as versatile platform in drug delivery applications
    • Svenson S,. 2009. Dendrimers as versatile platform in drug delivery applications. Eur J Pharm Biopharm 71: 445-462.
    • (2009) Eur J Pharm Biopharm , vol.71 , pp. 445-462
    • Svenson, S.1
  • 50
    • 14944365541 scopus 로고    scopus 로고
    • Gene-expression profiling reveals down-regulation of equilibrative nucleoside transporter 1 (ENT1) in Ara-C-resistant CCRF-CEM-derived cells
    • Takagaki K, Katsuma S, Kaminishi Y, Horio T, Nakagawa S, Tanaka T, Ohgi T, Yano J,. 2004. Gene-expression profiling reveals down-regulation of equilibrative nucleoside transporter 1 (ENT1) in Ara-C-resistant CCRF-CEM-derived cells. J Biochem 136: 733-740.
    • (2004) J Biochem , vol.136 , pp. 733-740
    • Takagaki, K.1    Katsuma, S.2    Kaminishi, Y.3    Horio, T.4    Nakagawa, S.5    Tanaka, T.6    Ohgi, T.7    Yano, J.8
  • 52
    • 72449212310 scopus 로고    scopus 로고
    • Cationic poly(amidoamine) dendrimer induces lysosomal apoptotic pathway at therapeutically relevant concentrations
    • Thomas TP, Majoros I, Kotlyar A, Mullen D, Holl MM, Baker JR,. 2009. Cationic poly(amidoamine) dendrimer induces lysosomal apoptotic pathway at therapeutically relevant concentrations. Biomacromolecules 10: 3207-3214.
    • (2009) Biomacromolecules , vol.10 , pp. 3207-3214
    • Thomas, T.P.1    Majoros, I.2    Kotlyar, A.3    Mullen, D.4    Holl, M.M.5    Baker, J.R.6
  • 53
    • 0025373701 scopus 로고
    • Starbust dendrimers: Molecular-level control of size shape surface chemistry topology and flexibility from atoms to macroscopic matter
    • Tomalia DA, Naylor AM, Goddard WA,. 1990. Starbust dendrimers: molecular-level control of size shape surface chemistry topology and flexibility from atoms to macroscopic matter. Angew Chem Int Ed 29: 138-175.
    • (1990) Angew Chem Int Ed , vol.29 , pp. 138-175
    • Tomalia, D.A.1    Naylor, A.M.2    Goddard, W.A.3
  • 54
    • 71449085975 scopus 로고    scopus 로고
    • Target molecular therapies: Methods to enhance and monitor tumor drug delivery
    • Viglianti BL,. 2009. Target molecular therapies: methods to enhance and monitor tumor drug delivery. Abdom Imag 34: 686-695.
    • (2009) Abdom Imag , vol.34 , pp. 686-695
    • Viglianti, B.L.1
  • 55
    • 24344467910 scopus 로고    scopus 로고
    • Polyplex Nanogel formulations for drug delivery of cytotoxic nucleoside analogs
    • Vinogradov SV, Zeman AD, Batrakova EV, Kabanov AV,. 2005. Polyplex Nanogel formulations for drug delivery of cytotoxic nucleoside analogs. J Control Rel 107: 143-157.
    • (2005) J Control Rel , vol.107 , pp. 143-157
    • Vinogradov, S.V.1    Zeman, A.D.2    Batrakova, E.V.3    Kabanov, A.V.4
  • 56
    • 0021953877 scopus 로고
    • Cytosine arabinoside transport and metabolism in acute leukemias and T cell lymphoblastic lymphoma
    • Wiley JS, Taupin J, Jamieson GP, Snook M, Sawyer WH, Finch LR,. 1985. Cytosine arabinoside transport and metabolism in acute leukemias and T cell lymphoblastic lymphoma. J Clin Invest 75: 632-642.
    • (1985) J Clin Invest , vol.75 , pp. 632-642
    • Wiley, J.S.1    Taupin, J.2    Jamieson, G.P.3    Snook, M.4    Sawyer, W.H.5    Finch, L.R.6
  • 57
    • 43449117468 scopus 로고    scopus 로고
    • Therapeutic and diagnostic applications of dendrimers for cancer treatment
    • Wolinsky JB, Grinstaff MW,. 2008. Therapeutic and diagnostic applications of dendrimers for cancer treatment. Adv Drug Deliv Rev 60: 1037-1055.
    • (2008) Adv Drug Deliv Rev , vol.60 , pp. 1037-1055
    • Wolinsky, J.B.1    Grinstaff, M.W.2
  • 58
    • 70349577793 scopus 로고    scopus 로고
    • Prestidge the encapsulation and release of guanosine from PEGylated liposomes
    • Yan Er, Barnes TJ, Fornasiero D, Clive A,. 2009. Prestidge the encapsulation and release of guanosine from PEGylated liposomes. J Liposome Res 19: 29-36.
    • (2009) J Liposome Res , vol.19 , pp. 29-36
    • Yan, E.1    Barnes, T.J.2    Fornasiero, D.3    Clive, A.4
  • 60
    • 43249116148 scopus 로고    scopus 로고
    • Liposomal coencapsulated fludarabine and mitoxantrone for lymphoproliferative disorder treatment
    • Zhao X, Wu J, Muthusamy N, Byrd JC, Lee RJ,. 2007. Liposomal coencapsulated fludarabine and mitoxantrone for lymphoproliferative disorder treatment. J Pharm Sci 97: 1508-1518.
    • (2007) J Pharm Sci , vol.97 , pp. 1508-1518
    • Zhao, X.1    Wu, J.2    Muthusamy, N.3    Byrd, J.C.4    Lee, R.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.