-
1
-
-
40749151926
-
Efficacy and safety of varenicline for smoking cessation
-
Hays JT, Ebbert JO, Sood AS. Efficacy and safety of varenicline for smoking cessation. Am J Med. 2008;121(4 suppl 1):S32-S42.
-
(2008)
Am J Med
, vol.121
, Issue.4 SUPPL. 1
-
-
Hays, J.T.1
Ebbert, J.O.2
Sood, A.S.3
-
3
-
-
0033739654
-
Smoking and mental illness: A population based prevalence study
-
Lasser K, Boyd JW, Woolhandler S, Himmelstein DU, McCormick D, Bor DH. Smoking and mental illness: a population based prevalence study. JAMA. 2000;284(20):2606-2610.
-
(2000)
JAMA
, vol.284
, Issue.20
, pp. 2606-2610
-
-
Lasser, K.1
Boyd, J.W.2
Woolhandler, S.3
Himmelstein, D.U.4
McCormick, D.5
Bor, D.H.6
-
4
-
-
33745611449
-
Efficacy of varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, vs placebo or sustained-release bupropion for smoking cessation: A randomized controlled trial
-
Jorenby DE, Hays JT, Rigotti NA, et al. Efficacy of varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, vs placebo or sustained-release bupropion for smoking cessation: a randomized controlled trial. JAMA. 2006;296(1):56-63.
-
(2006)
JAMA
, vol.296
, Issue.1
, pp. 56-63
-
-
Jorenby, D.E.1
Hays, J.T.2
Rigotti, N.A.3
-
5
-
-
33745611449
-
Efficacy of varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, vs placebo or sustained-release bupropion for smoking cessation: A randomized controlled trial
-
Erratum in
-
Erratum in: JAMA. 2006;296(11):1355.
-
(2006)
JAMA
, vol.296
, Issue.11
, pp. 1355
-
-
Jorenby, D.E.1
Hays, J.T.2
Rigotti, N.A.3
-
6
-
-
33745599140
-
Effect of maintenance therapy with varenicline on smoking cessation: A randomized controlled trial
-
Tonstad S, Tonnesen P, Hajek P, et al. Effect of maintenance therapy with varenicline on smoking cessation: a randomized controlled trial. JAMA. 2006;296(1):64-71.
-
(2006)
JAMA
, vol.296
, Issue.1
, pp. 64-71
-
-
Tonstad, S.1
Tonnesen, P.2
Hajek, P.3
-
7
-
-
33747199571
-
Smoking cessation with varenicline, a selective α4β2 nicotinic receptor partial agonist: Results from a 7-week, randomized, placebo- and bupropion-controlled trial with 1-year follow-up
-
Nides M, Oncken C, Gonzales D, et al. Smoking cessation with varenicline, a selective α4β2 nicotinic receptor partial agonist: results from a 7-week, randomized, placebo- and bupropion-controlled trial with 1-year follow-up. Arch Intern Med. 2006;166(15):1561-1568.
-
(2006)
Arch Intern Med
, vol.166
, Issue.15
, pp. 1561-1568
-
-
Nides, M.1
Oncken, C.2
Gonzales, D.3
-
8
-
-
33747154992
-
Efficacy and safety of the novel selective nicotinic acetylcholine receptor partial agonist, varenicline, for smoking cessation
-
Oncken C, Gonzales D, Nides M, et al. Efficacy and safety of the novel selective nicotinic acetylcholine receptor partial agonist, varenicline, for smoking cessation. Arch Intern Med. 2006;166(15):1571-1577.
-
(2006)
Arch Intern Med
, vol.166
, Issue.15
, pp. 1571-1577
-
-
Oncken, C.1
Gonzales, D.2
Nides, M.3
-
9
-
-
33745614361
-
Varenicline, an α4β2 nicotinic acetylcholine receptor partial agonist, vs sustained-release buproprion and placebo for smoking cessation: A randomized controlled trial
-
Gonzales D, Rennard SI, Nides M, et al. Varenicline, an α4β2 nicotinic acetylcholine receptor partial agonist, vs sustained-release buproprion and placebo for smoking cessation: a randomized controlled trial. JAMA. 2006;296(1):47-55.
-
(2006)
JAMA
, vol.296
, Issue.1
, pp. 47-55
-
-
Gonzales, D.1
Rennard, S.I.2
Nides, M.3
-
10
-
-
47549112072
-
Treating Tobacco Use and Dependence: 2008 Update
-
Rockville, MD: U.S. Department of Health and Human Services. Public Health Service. May
-
Fiore MC, Jaén CR, Baker TB, et al. Treating Tobacco Use and Dependence: 2008 Update. Clinical Practice Guideline. Rockville, MD: U.S. Department of Health and Human Services. Public Health Service. May 2008.
-
(2008)
Clinical Practice Guideline
-
-
Fiore, M.C.1
Jaén, C.R.2
Baker, T.B.3
-
11
-
-
34548142181
-
Varenicline: A review of the literature and place in therapy
-
Whitley HP, Moorman KL. Varenicline: a review of the literature and place in therapy. Pharmacy Practice. 2007;5(2):51-58.
-
(2007)
Pharmacy Practice
, vol.5
, Issue.2
, pp. 51-58
-
-
Whitley, H.P.1
Moorman, K.L.2
-
12
-
-
43949124868
-
Cost-utility analysis of varenicline versus existing smoking cessation strategies using the BENESCO simulation model: Application to a population of US adult smokers
-
Howard P, Knight C, Boler A, Baker C. Cost-utility analysis of varenicline versus existing smoking cessation strategies using the BENESCO simulation model: application to a population of US adult smokers. Pharmacoeconomics. 2008;26(6):497-511.
-
(2008)
Pharmacoeconomics
, vol.26
, Issue.6
, pp. 497-511
-
-
Howard, P.1
Knight, C.2
Boler, A.3
Baker, C.4
-
13
-
-
77149151846
-
The cost effectiveness of an extended course (12 +12 weeks) of varenicline compared with other available smoking cessation strategies in the United States: An extension and update to the BENESCO model
-
Knight C, Howard P, Baker CL, Marton JP. The cost effectiveness of an extended course (12 +12 weeks) of varenicline compared with other available smoking cessation strategies in the United States: an extension and update to the BENESCO model. Value Health. 2010;13(2):209-214.
-
(2010)
Value Health
, vol.13
, Issue.2
, pp. 209-214
-
-
Knight, C.1
Howard, P.2
Baker, C.L.3
Marton, J.P.4
-
14
-
-
76349119987
-
-
New York, NY: Pfizer Labs
-
Chantix [package insert]. New York, NY: Pfizer Labs; 2009.
-
(2009)
Chantix [package Insert]
-
-
-
15
-
-
33750264137
-
Varenicline: A review of its use as an aid to smoking cessation therapy
-
Keating GM, Siddiqui MA. Varenicline: a review of its use as an aid to smoking cessation therapy. CNS Drugs. 2006;20(11):945-960.
-
(2006)
CNS Drugs
, vol.20
, Issue.11
, pp. 945-960
-
-
Keating, G.M.1
Siddiqui, M.A.2
-
17
-
-
84869280663
-
-
New York Times. May 22, 2008. Available at, Accessed August 4
-
Saul S. F.A.A. bans antismoking drug, citing side effects. New York Times. May 22, 2008. Available at: www.nytimes.com/2008/05/22/business/22drug.html. Accessed August 4, 2010.
-
(2010)
Bans Antismoking Drug, Citing Side Effects
-
-
Saul, S.F.A.A.1
-
19
-
-
78649675736
-
-
U.S. Food and Drug Administration, Available at, Accessed July 28
-
U.S. Food and Drug Administration. Early communication about an ongoing safety review: varenicline (marketed as chantix). Available at: www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInformationforPatientsandProviders/DrugSafetyInformationforHeathcareProfessionals/ucm070765.htm. Accessed July 28, 2010.
-
(2010)
Early Communication About An Ongoing Safety Review: Varenicline (marketed as Chantix)
-
-
-
21
-
-
67650504189
-
Chantix-induced mental status changes in a young healthy female
-
Kutscher EC, Stanley M, Oehlke K. Chantix-induced mental status changes in a young healthy female. S D Med. 2009;62(5):193,195.
-
(2009)
S D Med
, vol.62
, Issue.5
-
-
Kutscher, E.C.1
Stanley, M.2
Oehlke, K.3
-
22
-
-
66149167339
-
Hallucinations in the context of varenicline withdrawal
-
Laine P, Marttlia J, Lindeman S. Hallucinations in the context of varenicline withdrawal. Am J Psychiatry. 2009;166(5):619-620.
-
(2009)
Am J Psychiatry
, vol.166
, Issue.5
, pp. 619-620
-
-
Laine, P.1
Marttlia, J.2
Lindeman, S.3
-
23
-
-
66249112505
-
Safety and drug utilization profile of varenicline as used in general practice in England: Interim results from a prescription-event monitoring study
-
Kasliwal R, Wilton LV, Shakir SA. Safety and drug utilization profile of varenicline as used in general practice in England: interim results from a prescription-event monitoring study. Drug Saf. 2009;32(6):499-507.
-
(2009)
Drug Saf
, vol.32
, Issue.6
, pp. 499-507
-
-
Kasliwal, R.1
Wilton, L.V.2
Shakir, S.A.3
-
24
-
-
70449392796
-
Varenicline and suicidal behavior: A cohort study based on data from the General Practice Research Database
-
Gunnell D, Irvine D, Wise L, Davies C, Martin RM. Varenicline and suicidal behavior: a cohort study based on data from the General Practice Research Database. BMJ. 2009;339:b3805.
-
(2009)
BMJ
, vol.339
-
-
Gunnell, D.1
Irvine, D.2
Wise, L.3
Davies, C.4
Martin, R.M.5
-
25
-
-
46949099038
-
Varenicline-induced mixed mood and psychotic episode in a patient with a past history of depression
-
Pumariega AJ, Nelson R, Rotenberg L. Varenicline-induced mixed mood and psychotic episode in a patient with a past history of depression. CNS Spectr. 2008;13(6):511-514.
-
(2008)
CNS Spectr
, vol.13
, Issue.6
, pp. 511-514
-
-
Pumariega, A.J.1
Nelson, R.2
Rotenberg, L.3
-
26
-
-
51649123202
-
Neuropsychiatric disturbance after initiation of varenicline in a patient with a history of alcohol abuse and major depression
-
Pirmoradi P, Roshan S, Nadeem SS. Neuropsychiatric disturbance after initiation of varenicline in a patient with a history of alcohol abuse and major depression. Am J Health Syst Pharm. 2008;65(17):1624-1626.
-
(2008)
Am J Health Syst Pharm
, vol.65
, Issue.17
, pp. 1624-1626
-
-
Pirmoradi, P.1
Roshan, S.2
Nadeem, S.S.3
-
27
-
-
59049103876
-
Possible varenicline-induced paranoia and irritability in a patient with major depressive disorder, borderline personality disorder, and methamphetamine abuse in remission
-
Lyon GJ. Possible varenicline-induced paranoia and irritability in a patient with major depressive disorder, borderline personality disorder, and methamphetamine abuse in remission. J Clin Psychopharmacol. 2008;28(6):720-721.
-
(2008)
J Clin Psychopharmacol
, vol.28
, Issue.6
, pp. 720-721
-
-
Lyon, G.J.1
-
28
-
-
72449148717
-
Visual hallucinations associated with varenicline: A case report
-
Raidoo BM and Kutscher EC. Visual hallucinations associated with varenicline: a case report. J Med Case Reports. 2009;3:7560.
-
(2009)
J Med Case Reports
, vol.3
, pp. 7560
-
-
Raidoo, B.M.1
Kutscher, E.C.2
-
29
-
-
39049140884
-
Hypomania with agitation associated with varenicline use in bipolar II disorder
-
Morstad AE, Kutscher EC, Kennedy WK, Carnahan RM. Hypomania with agitation associated with varenicline use in bipolar II disorder. Ann Pharmacother. 2008;42(2):288-289.
-
(2008)
Ann Pharmacother
, vol.42
, Issue.2
, pp. 288-289
-
-
Morstad, A.E.1
Kutscher, E.C.2
Kennedy, W.K.3
Carnahan, R.M.4
-
30
-
-
34548073110
-
Varenicline-induced manic episode in a patient with bipolar disorder
-
Kohen I, Kremen N. Varenicline-induced manic episode in a patient with bipolar disorder. Am J Psychiatry. 2007;164(8):1269-1270.
-
(2007)
Am J Psychiatry
, vol.164
, Issue.8
, pp. 1269-1270
-
-
Kohen, I.1
Kremen, N.2
-
31
-
-
67650818286
-
Worsening psychosis induced by varenicline in a hospitalized psychiatric patient
-
DiPaula BA, Thomas MD. Worsening psychosis induced by varenicline in a hospitalized psychiatric patient. Pharmacotherapy. 2009;29(7):852-857.
-
(2009)
Pharmacotherapy
, vol.29
, Issue.7
, pp. 852-857
-
-
Dipaula, B.A.1
Thomas, M.D.2
-
32
-
-
67749142170
-
Varenicline-induced mania in a bipolar patient
-
Alhatem F, Black JE. Varenicline-induced mania in a bipolar patient. Clin Neuropharmacol. 2009;32(2):117-118.
-
(2009)
Clin Neuropharmacol
, vol.32
, Issue.2
, pp. 117-118
-
-
Alhatem, F.1
Black, J.E.2
-
33
-
-
70350441886
-
Varenicline-induced mixed mood and psychotic episode in a patient with schizoaffective disorder
-
Liu ME, Tsai SJ, Yang ST. Varenicline-induced mixed mood and psychotic episode in a patient with schizoaffective disorder. CNS Spectr. 2009;14(7):346.
-
(2009)
CNS Spectr
, vol.14
, Issue.7
, pp. 346
-
-
Liu, M.E.1
Tsai, S.J.2
Yang, S.T.3
-
34
-
-
34548071446
-
Exacerbation of schizophrenia by varenicline
-
Freedman R. Exacerbation of schizophrenia by varenicline. Am J Psychiatry. 2007;164(8):1269.
-
(2007)
Am J Psychiatry
, vol.164
, Issue.8
, pp. 1269
-
-
Freedman, R.1
-
35
-
-
65749117519
-
Safety and effectiveness of varenicline in a veteran population with a high prevalence of mental illness
-
Purvis TL, Mambourg SE, Balvanz TM, Magallon HE, Pham RH. Safety and effectiveness of varenicline in a veteran population with a high prevalence of mental illness. Ann Pharmacother. 2009;43(5):862-867.
-
(2009)
Ann Pharmacother
, vol.43
, Issue.5
, pp. 862-867
-
-
Purvis, T.L.1
Mambourg, S.E.2
Balvanz, T.M.3
Magallon, H.E.4
Pham, R.H.5
-
36
-
-
36849027596
-
Varenicline in the routine treatment of tobacco dependence: A pre-post comparison with nicotine replacement therapy and an evaluation in those with mental illness
-
Stapleton JA, Watson L, Spirling LI, et al. Varenicline in the routine treatment of tobacco dependence: a pre-post comparison with nicotine replacement therapy and an evaluation in those with mental illness. Addiction. 2008;103(1):146-154.
-
(2008)
Addiction
, vol.103
, Issue.1
, pp. 146-154
-
-
Stapleton, J.A.1
Watson, L.2
Spirling, L.I.3
-
37
-
-
46749109721
-
Varenicline treatment for smokers with schizophrenia: A case series
-
Evins AE, Goff DC. Varenicline treatment for smokers with schizophrenia: a case series. J Clin Psychiatry. 2008;69(6):1016.
-
(2008)
J Clin Psychiatry
, vol.69
, Issue.6
, pp. 1016
-
-
Evins, A.E.1
Goff, D.C.2
-
38
-
-
47249085518
-
Varenicline efficacy and safety in a subject with schizophrenia
-
Fatemi SH. Varenicline efficacy and safety in a subject with schizophrenia. Schizophrenia Res. 2008;103(1-3):328-329.
-
(2008)
Schizophrenia Res
, vol.103
, Issue.1-3
, pp. 328-329
-
-
Fatemi, S.H.1
-
39
-
-
65349104738
-
Varenicline reduced smoking behavior in a mentally ill person
-
Ochoa EL. Varenicline reduced smoking behavior in a mentally ill person. J Psychopharmacol. 2009;23(3):340-341.
-
(2009)
J Psychopharmacol
, vol.23
, Issue.3
, pp. 340-341
-
-
Ochoa, E.L.1
-
40
-
-
67349146819
-
Mood, side effects and smoking outcomes among persons with and without probable lifetime depression taking varenicline
-
McClure JB, Swan GE, Jack L, et al. Mood, side effects and smoking outcomes among persons with and without probable lifetime depression taking varenicline. J Gen Intern Med. 2009;24(5):563-569.
-
(2009)
J Gen Intern Med
, vol.24
, Issue.5
, pp. 563-569
-
-
McClure, J.B.1
Swan, G.E.2
Jack, L.3
-
41
-
-
68049135884
-
Varenicline augmentation in depressed smokers: An 8 week, open label study
-
Phillip NS, Carpenter LL, Tyrka AR, Whiteley LB, Price LH. Varenicline augmentation in depressed smokers: an 8 week, open label study. J Clin Psychiatry. 2009;70(7):1026-1031.
-
(2009)
J Clin Psychiatry
, vol.70
, Issue.7
, pp. 1026-1031
-
-
Phillip, N.S.1
Carpenter, L.L.2
Tyrka, A.R.3
Whiteley, L.B.4
Price, L.H.5
-
42
-
-
57849159726
-
Varenicline improves mood and cognition during smoking abstinence
-
Patterson F, Jepson C, Strasser AA, et al. Varenicline improves mood and cognition during smoking abstinence. Biol Psychiatry. 2009;65(2):144-149.
-
(2009)
Biol Psychiatry
, vol.65
, Issue.2
, pp. 144-149
-
-
Patterson, F.1
Jepson, C.2
Strasser, A.A.3
-
43
-
-
33747598710
-
Varenicline is a partial agonist at α4β2 and a full agonist at α7 neuronal nicotinic receptors
-
Mihalak KB, Carroll FI, Luetje CW. Varenicline is a partial agonist at α4β2 and a full agonist at α7 neuronal nicotinic receptors. Mol Pharmacol. 2006;70(3):801-805.
-
(2006)
Mol Pharmacol
, vol.70
, Issue.3
, pp. 801-805
-
-
Mihalak, K.B.1
Carroll, F.I.2
Luetje, C.W.3
-
44
-
-
68949180394
-
Schizophrenia
-
van Os J, Kapur S. Schizophrenia. Lancet. 2009;374(9690):635-645.
-
(2009)
Lancet
, vol.374
, Issue.9690
, pp. 635-645
-
-
van Os, J.1
Kapur, S.2
-
45
-
-
71049173312
-
The role of dopamine in bipolar disorder
-
Cousins DA, Butts K, Young AH. The role of dopamine in bipolar disorder. Bipolar Disord. 2009;11(8):787-806.
-
(2009)
Bipolar Disord
, vol.11
, Issue.8
, pp. 787-806
-
-
Cousins, D.A.1
Butts, K.2
Young, A.H.3
-
46
-
-
61449197838
-
Neurobiological mechanisms in major depressive disorder
-
aan het Rot M, Mathew SJ, Charney DS. Neurobiological mechanisms in major depressive disorder. CMAJ. 2009;180(3):305-313.
-
(2009)
CMAJ
, vol.180
, Issue.3
, pp. 305-313
-
-
aan het Rot, M.1
Mathew, S.J.2
Charney, D.S.3
-
47
-
-
60349101359
-
Varenicline has antidepressant-like activity in the forced swim test and augments sertraline's effect
-
Rollema H, Guanowsky V, Mineur YS, et al. Varenicline has antidepressant-like activity in the forced swim test and augments sertraline's effect. Eur J Pharmacol. 2009;605(1-3):114-116.
-
(2009)
Eur J Pharmacol
, vol.605
, Issue.1-3
, pp. 114-116
-
-
Rollema, H.1
Guanowsky, V.2
Mineur, Y.S.3
-
48
-
-
0034061482
-
Development of major depression after treatment for smoking cessation
-
Tsoh JY, Humfleet GL, Munoz RF, Reus VI, Hartz DT, Hall SM. Development of major depression after treatment for smoking cessation. Am J Psychiatry. 2000;157(3):368-374.
-
(2000)
Am J Psychiatry
, vol.157
, Issue.3
, pp. 368-374
-
-
Tsoh, J.Y.1
Humfleet, G.L.2
Munoz, R.F.3
Reus, V.I.4
Hartz, D.T.5
Hall, S.M.6
-
49
-
-
34948846642
-
Interference with smoking cessation effects of varenicline after administration of immediate release amphetamine-dextroamphetamine
-
Whitley HP, Moorman KL. Interference with smoking cessation effects of varenicline after administration of immediate release amphetamine-dextroamphetamine. Pharmacotherapy. 2007;27(10):1440-1445.
-
(2007)
Pharmacotherapy
, vol.27
, Issue.10
, pp. 1440-1445
-
-
Whitley, H.P.1
Moorman, K.L.2
-
50
-
-
60249086665
-
Deaths: Preliminary data for 2006
-
Available at, Accessed July 28, 2010
-
Heron MP, Hoyert DL, Xu JQ, Scott C, Tejada-Vera B. Deaths: preliminary data for 2006. Natl Vital Stat Rep. 2008;56(16). Available at: www.cdc.gov/nchs/data/nvsr/nvsr56/nvsr56_16.pdf. Accessed July 28, 2010.
-
(2008)
Natl Vital Stat Rep
, vol.56
, Issue.16
-
-
Heron, M.P.1
Hoyert, D.L.2
Xu, J.Q.3
Scott, C.4
Tejada-Vera, B.5
-
51
-
-
78649644263
-
Suicide
-
Centers for Disease Control and Prevention, Summer 2009. Available at, Accessed August 4
-
Centers for Disease Control and Prevention. Suicide. Facts at a Glance. Summer 2009. Available at: www.cdc.gov/violenceprevention/pdf/Suicide-DataSheet-a.pdf. Accessed August 4, 2010.
-
(2010)
Facts at a Glance
-
-
-
52
-
-
84877598164
-
-
U.S. Food and Drug Administration, Available at, Accessed July 28
-
U.S. Food and Drug Administration. Information for healthcare professionals: varenicline (marketed as chantix). Available at: www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInformationforPatientsandProviders/ucm124818.htm. Accessed July 28, 2010.
-
(2010)
Information for Healthcare Professionals: Varenicline (marketed as Chantix)
-
-
|