Epigenetic modifications in neurons are essential for formation and storage of behavioral memory

Neuropsychopharmacology

Volumn 36, Issue 1, 2011, Pages 357-358

  Day, Jeremy J ^a   Sweatt, J David ^a  

^a University of Alabama at Birmingham   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; DNA; HISTONE; PHOSPHOPROTEIN PHOSPHATASE 1; REELIN;

ACETYLATION; BEHAVIOR CHANGE; BEHAVIORAL MEMORY; BRAIN FUNCTION; DNA METHYLATION; EPIGENETICS; FEATHER; HUMAN; LEARNING; MEMORY; MEMORY CONSOLIDATION; MOLECULAR MECHANICS; NERVE CELL; NERVE CELL PLASTICITY; PRIORITY JOURNAL; SHORT SURVEY;

ACETYLATION; ANIMALS; BEHAVIOR; BRAIN CHEMISTRY; DNA METHYLATION; EPIGENESIS, GENETIC; GENE EXPRESSION REGULATION; HUMANS; LEARNING; MEMORY; NEURONAL PLASTICITY; NEURONS;

EID: 78649649142     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1038/npp.2010.125     Document Type: Short Survey

References (6)

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2. Levenson JM, O'Riordan KJ, Brown KD, Trinh MA, Molfese DL, Sweatt JD (2004). Regulation of histone acetylation during memory formation in the hippocampus. J Biol Chem 279: 40545-40559.
3. Lubin FD, Sweatt JD (2007). The IkappaB kinase regulates chromatin structure during reconsolida-tion of conditioned fear memories. Neuron 55: 942-957.
4. Miller CA, Sweatt JD (2007). Covalent modification of DNA regulates memory formation. Neuron 53: 857-869.
5. Miller CA, Gavin CF, White JA, Parrish RR, Honasoge A, Yancey CR et al (2010). Cortical DNA methylation maintains remote memory. Nat Neurosci 13: 664-666.
6. Peleg S, Sananbenesi F, Zovoilis A, Burkhardt S, Bahari-JaVan S, Agis-Balboa RC et al. (2010). Altered histone acetylation is associated with age-dependent memory impairment in mice. Science 328: 753-756.